TW347389B - Taxoids, their preparation and pharmaceutical compositions containing them - Google Patents

Taxoids, their preparation and pharmaceutical compositions containing them

Info

Publication number
TW347389B
TW347389B TW085103805A TW85103805A TW347389B TW 347389 B TW347389 B TW 347389B TW 085103805 A TW085103805 A TW 085103805A TW 85103805 A TW85103805 A TW 85103805A TW 347389 B TW347389 B TW 347389B
Authority
TW
Taiwan
Prior art keywords
taxoids
preparation
pharmaceutical compositions
compositions containing
alkyl
Prior art date
Application number
TW085103805A
Other languages
English (en)
Inventor
Bouchard Herve
Bourzat Jean-Dominique
Commercon Alain
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of TW347389B publication Critical patent/TW347389B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
TW085103805A 1995-04-03 1996-04-01 Taxoids, their preparation and pharmaceutical compositions containing them TW347389B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9503868A FR2732342B1 (fr) 1995-04-03 1995-04-03 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
TW347389B true TW347389B (en) 1998-12-11

Family

ID=9477663

Family Applications (1)

Application Number Title Priority Date Filing Date
TW085103805A TW347389B (en) 1995-04-03 1996-04-01 Taxoids, their preparation and pharmaceutical compositions containing them

Country Status (32)

Country Link
US (1) US5959125A (zh)
EP (1) EP0821680B1 (zh)
JP (1) JPH11504004A (zh)
KR (1) KR19980703520A (zh)
CN (1) CN1073106C (zh)
AP (1) AP784A (zh)
AR (1) AR002730A1 (zh)
AT (1) ATE195940T1 (zh)
AU (1) AU703918B2 (zh)
BG (1) BG62964B1 (zh)
BR (1) BR9604799A (zh)
CA (1) CA2214322C (zh)
CZ (1) CZ287430B6 (zh)
DE (1) DE69610085T2 (zh)
DK (1) DK0821680T3 (zh)
EA (1) EA000726B1 (zh)
ES (1) ES2151155T3 (zh)
FR (1) FR2732342B1 (zh)
GE (1) GEP19991872B (zh)
GR (1) GR3034203T3 (zh)
HU (1) HUP9802042A3 (zh)
IL (1) IL117760A (zh)
MX (1) MX9707427A (zh)
NO (1) NO974563L (zh)
NZ (1) NZ305898A (zh)
PL (1) PL322581A1 (zh)
PT (1) PT821680E (zh)
RO (1) RO115879B1 (zh)
SK (1) SK282047B6 (zh)
TW (1) TW347389B (zh)
WO (1) WO1996031493A1 (zh)
ZA (1) ZA962633B (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
FR2764118B1 (fr) * 1997-05-30 2000-08-04 Thomson Csf Transistor bipolaire stabilise avec elements isolants electriques
US6156789A (en) * 1998-03-17 2000-12-05 Rhone-Poulenc Rorer S.A. Method for treating abnormal cell proliferation in the brain
EP1176957A1 (en) * 1999-05-03 2002-02-06 Aventis Pharma S.A. Method for treating abnormal cell proliferation in the brain
JP2003522171A (ja) 2000-02-02 2003-07-22 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 抗腫瘍剤としてのc10カーボネート置換タキサン
US6649632B2 (en) * 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
NZ514407A (en) * 2000-02-02 2004-12-24 Univ Florida State Res Found C10 carbamoyloxy substituted taxanes as antitumor agents
JP2004339475A (ja) * 2003-02-03 2004-12-02 Merck Patent Gmbh フッ化物、オキシフッ化物、フルオロ硫化物および/またはオキシフルオロ硫化物に基づく真珠光沢顔料
CA2526278A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
HN2005000054A (es) 2004-02-13 2009-02-18 Florida State University Foundation Inc Taxanos sustituidos con esteres de ciclopentilo en c10
AU2006214498A1 (en) * 2005-02-14 2006-08-24 Florida State University Research Foundation, Inc. C10 cyclopropyl ester substituted taxane compositions
JP2011517455A (ja) * 2008-03-31 2011-06-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド C(10)エチルエステルおよびc(10)シクロプロピルエステル置換タキサン

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302520B1 (no) * 1992-07-01 1998-03-16 Bristol Myers Squibb Co Fluortaxoler, mellomprodukt til fremstilling derav, samt farmasöytisk preparat inneholdende dem
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
IL107950A (en) * 1992-12-15 2001-04-30 Upjohn Co b 7, b 8 - Matano - Taxols, their preparation and pharmaceutical preparations against malignant tumors containing them

Also Published As

Publication number Publication date
AU5402896A (en) 1996-10-23
AP784A (en) 1999-11-22
DK0821680T3 (da) 2000-11-20
EP0821680B1 (fr) 2000-08-30
SK133397A3 (en) 1998-02-04
ZA962633B (en) 1996-10-07
CN1073106C (zh) 2001-10-17
NO974563D0 (no) 1997-10-02
BG62964B1 (bg) 2000-12-29
ATE195940T1 (de) 2000-09-15
BR9604799A (pt) 1999-04-06
CN1179777A (zh) 1998-04-22
EA000726B1 (ru) 2000-02-28
CZ310997A3 (cs) 1998-01-14
GEP19991872B (en) 1999-12-06
ES2151155T3 (es) 2000-12-16
CA2214322C (fr) 2007-01-30
FR2732342A1 (fr) 1996-10-04
HUP9802042A2 (hu) 2000-06-28
NO974563L (no) 1997-11-24
AU703918B2 (en) 1999-04-01
CZ287430B6 (en) 2000-11-15
PL322581A1 (en) 1998-02-02
BG101940A (en) 1998-11-30
AP9701094A0 (en) 1997-10-31
EP0821680A1 (fr) 1998-02-04
WO1996031493A1 (fr) 1996-10-10
DE69610085T2 (de) 2001-01-11
US5959125A (en) 1999-09-28
FR2732342B1 (fr) 1997-04-30
PT821680E (pt) 2000-12-29
AR002730A1 (es) 1998-04-29
SK282047B6 (sk) 2001-10-08
DE69610085D1 (de) 2000-10-05
JPH11504004A (ja) 1999-04-06
MX9707427A (es) 1998-02-28
HUP9802042A3 (en) 2001-02-28
IL117760A0 (en) 1996-08-04
EA199700288A1 (ru) 1998-04-30
KR19980703520A (ko) 1998-11-05
GR3034203T3 (en) 2000-11-30
CA2214322A1 (fr) 1996-10-10
NZ305898A (en) 1998-12-23
RO115879B1 (ro) 2000-07-28
IL117760A (en) 2001-11-25

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