ATE225787T1 - Arylsubstituierte heterocyclische verbindungen - Google Patents
Arylsubstituierte heterocyclische verbindungenInfo
- Publication number
- ATE225787T1 ATE225787T1 AT93610063T AT93610063T ATE225787T1 AT E225787 T1 ATE225787 T1 AT E225787T1 AT 93610063 T AT93610063 T AT 93610063T AT 93610063 T AT93610063 T AT 93610063T AT E225787 T1 ATE225787 T1 AT E225787T1
- Authority
- AT
- Austria
- Prior art keywords
- aryl
- substituted heterocyclic
- heterocyclic compounds
- compounds
- chem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK921541A DK154192D0 (da) | 1992-12-23 | 1992-12-23 | Heterocycliske forbindelser |
DK71893A DK71893D0 (da) | 1993-06-18 | 1993-06-18 | Heterocykliske forbindelser |
US08/093,184 US5554626A (en) | 1992-12-23 | 1993-07-16 | Substituted heterocyclic compounds as dopamine-reuptake inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE225787T1 true ATE225787T1 (de) | 2002-10-15 |
Family
ID=27220884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93610063T ATE225787T1 (de) | 1992-12-23 | 1993-12-20 | Arylsubstituierte heterocyclische verbindungen |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0604352B1 (de) |
JP (1) | JPH06293760A (de) |
AT (1) | ATE225787T1 (de) |
AU (1) | AU672644B2 (de) |
CA (1) | CA2112083C (de) |
DE (1) | DE69332366T2 (de) |
FI (1) | FI935799A (de) |
NO (1) | NO301227B1 (de) |
NZ (1) | NZ250514A (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6329520B1 (en) * | 1990-08-09 | 2001-12-11 | Research Triangle Institute | Cocaine receptor binding ligands |
DE69623799T2 (de) * | 1995-11-02 | 2003-01-30 | Neurosearch As Ballerup | Kondensierte tropanderivate als neurotransmitter-reuptake-inhibitoren |
ZA971525B (en) * | 1996-02-22 | 1997-10-21 | Neurosearch As | Tropane derivatives, their preparation and use. |
US6350758B1 (en) * | 1996-12-02 | 2002-02-26 | Georgetown University | Tropane derivatives and method for their synthesis |
GB9915617D0 (en) * | 1999-07-05 | 1999-09-01 | Knoll Ag | Therapeutic agents |
US7381733B2 (en) | 2001-11-30 | 2008-06-03 | Neurosearch A/S | Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases |
WO2005039580A1 (en) | 2003-10-16 | 2005-05-06 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an acetylcholinesterase inhibitor |
EP1779851A1 (de) | 2005-10-31 | 2007-05-02 | Boehringer Ingelheim Pharma GmbH & Co.KG | Behandlung von Diabetes |
US20100035914A1 (en) * | 2006-09-11 | 2010-02-11 | Barbara Bertani | Azabicyclic compounds as inhibitors of monoamines reuptake |
WO2010125033A1 (en) * | 2009-04-29 | 2010-11-04 | Glaxo Group Limited | Azabicyclo[4.1.0]heptane derivatives |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3813404A (en) * | 1972-11-15 | 1974-05-28 | Sterling Drug Inc | Tropane-2-carboxylates and derivatives |
FR2276823A1 (fr) * | 1974-07-04 | 1976-01-30 | Roussel Uclaf | Nouveaux derives de la dibenzo(b.e)thiepine et leurs sels, procede de preparation et application a titre de medicaments desdits produits |
NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
IL88156A (en) * | 1987-11-13 | 1997-02-18 | Novo Nordisk As | Azacyclic compounds their preparation and pharmaceutical compositions containing them |
NZ227684A (en) * | 1988-01-30 | 1991-07-26 | Merck Sharp & Dohme | Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions |
ES2098248T3 (es) * | 1989-05-17 | 1997-05-01 | Pfizer | Derivados de 2-piperidino-1-alcanoles como agentes antiisquemicos. |
DK198590D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
EP0644775B1 (de) * | 1991-11-15 | 1999-08-04 | Research Triangle Institute | Kokainrezeptor bindende Liganden |
US5262428A (en) * | 1992-03-13 | 1993-11-16 | Wake Forest University | Biologically active tropane derivatives |
US5268480A (en) * | 1992-09-22 | 1993-12-07 | Mayo Foundation For Medical Education And Research | Cocaine analogs |
AU671163B2 (en) * | 1992-12-23 | 1996-08-15 | Neurosearch A/S | Alkyl substituted heterocyclic compounds |
-
1993
- 1993-12-13 AU AU52363/93A patent/AU672644B2/en not_active Ceased
- 1993-12-20 EP EP93610063A patent/EP0604352B1/de not_active Expired - Lifetime
- 1993-12-20 DE DE69332366T patent/DE69332366T2/de not_active Expired - Lifetime
- 1993-12-20 AT AT93610063T patent/ATE225787T1/de not_active IP Right Cessation
- 1993-12-20 NZ NZ250514A patent/NZ250514A/en unknown
- 1993-12-21 CA CA002112083A patent/CA2112083C/en not_active Expired - Fee Related
- 1993-12-22 JP JP5324475A patent/JPH06293760A/ja not_active Ceased
- 1993-12-22 FI FI935799A patent/FI935799A/fi unknown
- 1993-12-22 NO NO934760A patent/NO301227B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69332366D1 (de) | 2002-11-14 |
FI935799A (fi) | 1994-06-24 |
EP0604352A3 (de) | 1995-02-08 |
NO301227B1 (no) | 1997-09-29 |
DE69332366T2 (de) | 2003-06-18 |
CA2112083C (en) | 2002-02-19 |
AU5236393A (en) | 1994-07-07 |
NZ250514A (en) | 1996-03-26 |
AU672644B2 (en) | 1996-10-10 |
FI935799A0 (fi) | 1993-12-22 |
NO934760L (no) | 1994-06-24 |
NO934760D0 (no) | 1993-12-22 |
EP0604352B1 (de) | 2002-10-09 |
EP0604352A2 (de) | 1994-06-29 |
JPH06293760A (ja) | 1994-10-21 |
CA2112083A1 (en) | 1994-06-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |