SK282020B6 - Substituované 2-naftoylguanidíny, spôsob ich výroby, ich použitie ako liečiva alebo diagnostika, ako aj liečivo, ktoré ich obsahuje - Google Patents
Substituované 2-naftoylguanidíny, spôsob ich výroby, ich použitie ako liečiva alebo diagnostika, ako aj liečivo, ktoré ich obsahuje Download PDFInfo
- Publication number
- SK282020B6 SK282020B6 SK670-97A SK67097A SK282020B6 SK 282020 B6 SK282020 B6 SK 282020B6 SK 67097 A SK67097 A SK 67097A SK 282020 B6 SK282020 B6 SK 282020B6
- Authority
- SK
- Slovakia
- Prior art keywords
- carbon atoms
- group
- hydrogen
- alkyl
- atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19621483A DE19621483A1 (de) | 1996-05-29 | 1996-05-29 | Substituierte 2-Naphthoylguanidine, Verfahren zur ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (2)
Publication Number | Publication Date |
---|---|
SK67097A3 SK67097A3 (en) | 1997-12-10 |
SK282020B6 true SK282020B6 (sk) | 2001-10-08 |
Family
ID=7795549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK670-97A SK282020B6 (sk) | 1996-05-29 | 1997-05-27 | Substituované 2-naftoylguanidíny, spôsob ich výroby, ich použitie ako liečiva alebo diagnostika, ako aj liečivo, ktoré ich obsahuje |
Country Status (29)
Country | Link |
---|---|
US (1) | US6087304A (no) |
EP (1) | EP0810206B1 (no) |
JP (1) | JP4039588B2 (no) |
KR (1) | KR970074776A (no) |
CN (1) | CN1167759A (no) |
AR (1) | AR008373A1 (no) |
AT (1) | ATE198320T1 (no) |
AU (1) | AU710065B2 (no) |
BR (1) | BR9703338A (no) |
CA (1) | CA2206366C (no) |
CZ (1) | CZ163097A3 (no) |
DE (2) | DE19621483A1 (no) |
DK (1) | DK0810206T3 (no) |
ES (1) | ES2154002T3 (no) |
GR (1) | GR3035126T3 (no) |
HR (1) | HRP970292B1 (no) |
HU (1) | HUP9700955A3 (no) |
ID (1) | ID16989A (no) |
IL (1) | IL120924A (no) |
NO (1) | NO308527B1 (no) |
NZ (1) | NZ314915A (no) |
PL (1) | PL185754B1 (no) |
PT (1) | PT810206E (no) |
RU (1) | RU2190600C2 (no) |
SI (1) | SI0810206T1 (no) |
SK (1) | SK282020B6 (no) |
TR (1) | TR199700428A2 (no) |
TW (1) | TW416944B (no) |
ZA (1) | ZA974665B (no) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19621482A1 (de) | 1996-05-29 | 1997-12-04 | Hoechst Ag | Substituierte 1-Naphthoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
WO2000051998A1 (en) | 1999-03-02 | 2000-09-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compounds useful as reversible inhibitors of cathepsin s |
US6420364B1 (en) | 1999-09-13 | 2002-07-16 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compound useful as reversible inhibitors of cysteine proteases |
PE20040167A1 (es) * | 2002-03-28 | 2004-05-26 | Novartis Ag | Amidas del acido sulfamico |
DK1755593T3 (da) * | 2004-06-02 | 2008-05-19 | Hoffmann La Roche | Naphtalenderivater der er nyttige som histamin-3-receptorligander |
TW200614995A (en) * | 2004-11-10 | 2006-05-16 | Nicholas Piramal India Ltd | Tricyclic guanidine derivatives as sodium-proton exchange inhibitors |
AU2013205388B2 (en) * | 2005-06-24 | 2016-05-05 | Biotron Limited | Antiviral compounds and methods |
KR20140072101A (ko) * | 2005-06-24 | 2014-06-12 | 바이오트론 리미티드 | 항바이러스 화합물 및 방법 |
ATE478847T1 (de) * | 2006-09-15 | 2010-09-15 | Pfizer | Substituierte pyridylmethylbicyclocarboxyamidverbindungen |
US20120041036A1 (en) * | 2009-02-09 | 2012-02-16 | Isao Kinoyama | Substituted acylguanidine derivatives (as amended) |
JPWO2010090304A1 (ja) * | 2009-02-09 | 2012-08-09 | アステラス製薬株式会社 | アシルグアニジン誘導体 |
TW201116281A (en) * | 2009-08-06 | 2011-05-16 | Astellas Pharma Inc | N atom containing ring acylguanidine derivatives |
PT2671869E (pt) | 2011-02-02 | 2016-01-11 | Astellas Pharma Inc | Derivado de tetra-hidroisoquinolina |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4251545A (en) * | 1979-09-19 | 1981-02-17 | Gaf Corporation | Fungicidal process using 1-(alkoxyaroyl)guanidines |
IT1238227B (it) * | 1989-12-01 | 1993-07-12 | Modulo di smistamento per impianti di convogliamento a nastro e simili | |
DE4035961A1 (de) * | 1990-11-02 | 1992-05-07 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
IL109570A0 (en) * | 1993-05-17 | 1994-08-26 | Fujisawa Pharmaceutical Co | Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
DE4415873A1 (de) * | 1994-05-05 | 1995-11-09 | Hoechst Ag | Substituierte bizyklische Heteroaroylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
JPH08225513A (ja) * | 1994-12-21 | 1996-09-03 | Kanebo Ltd | ナフトイルグアニジン誘導体 |
DE19621482A1 (de) * | 1996-05-29 | 1997-12-04 | Hoechst Ag | Substituierte 1-Naphthoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1996
- 1996-05-29 DE DE19621483A patent/DE19621483A1/de not_active Withdrawn
-
1997
- 1997-02-28 PL PL97318723A patent/PL185754B1/pl not_active IP Right Cessation
- 1997-05-16 US US08/857,631 patent/US6087304A/en not_active Expired - Lifetime
- 1997-05-16 SI SI9730102T patent/SI0810206T1/xx unknown
- 1997-05-16 EP EP97108013A patent/EP0810206B1/de not_active Expired - Lifetime
- 1997-05-16 DE DE59702802T patent/DE59702802D1/de not_active Expired - Lifetime
- 1997-05-16 DK DK97108013T patent/DK0810206T3/da active
- 1997-05-16 ES ES97108013T patent/ES2154002T3/es not_active Expired - Lifetime
- 1997-05-16 AT AT97108013T patent/ATE198320T1/de not_active IP Right Cessation
- 1997-05-16 PT PT97108013T patent/PT810206E/pt unknown
- 1997-05-27 IL IL12092497A patent/IL120924A/en not_active IP Right Cessation
- 1997-05-27 CZ CZ971630A patent/CZ163097A3/cs unknown
- 1997-05-27 HR HR970292A patent/HRP970292B1/xx not_active IP Right Cessation
- 1997-05-27 NZ NZ314915A patent/NZ314915A/en unknown
- 1997-05-27 TW TW086107120A patent/TW416944B/zh not_active IP Right Cessation
- 1997-05-27 AR ARP970102253A patent/AR008373A1/es unknown
- 1997-05-27 AU AU23645/97A patent/AU710065B2/en not_active Ceased
- 1997-05-27 HU HU9700955A patent/HUP9700955A3/hu unknown
- 1997-05-27 CN CN97113187A patent/CN1167759A/zh active Pending
- 1997-05-27 TR TR97/00428A patent/TR199700428A2/xx unknown
- 1997-05-27 SK SK670-97A patent/SK282020B6/sk unknown
- 1997-05-28 CA CA002206366A patent/CA2206366C/en not_active Expired - Fee Related
- 1997-05-28 NO NO972433A patent/NO308527B1/no not_active IP Right Cessation
- 1997-05-28 ZA ZA9704665A patent/ZA974665B/xx unknown
- 1997-05-28 RU RU97109003/04A patent/RU2190600C2/ru not_active IP Right Cessation
- 1997-05-28 ID IDP971814A patent/ID16989A/id unknown
- 1997-05-28 KR KR1019970021107A patent/KR970074776A/ko not_active Application Discontinuation
- 1997-05-28 JP JP13822797A patent/JP4039588B2/ja not_active Expired - Fee Related
- 1997-05-30 BR BR9703338A patent/BR9703338A/pt not_active IP Right Cessation
-
2000
- 2000-12-28 GR GR20000402772T patent/GR3035126T3/el not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4081159B2 (ja) | フェニル−置換されたアルケニルカルボン酸グアニジド、それらの製法、医薬または診断剤としてのそれらの使用およびそれらを含有する医薬 | |
SK282020B6 (sk) | Substituované 2-naftoylguanidíny, spôsob ich výroby, ich použitie ako liečiva alebo diagnostika, ako aj liečivo, ktoré ich obsahuje | |
SK80395A3 (en) | Guanidines of phenylsubstituted alkenylcarboxilic acid bearing perfluororalkyl groups, their preparation method, their use for drug preparation or diagnostic substance, as well as drug containing them | |
SK282018B6 (sk) | Substituované guanididy kyseliny škoricovej, spôsob ich výroby, ich použitie ako liečiva alebo diagnostika, ako aj liečivo, ktoré ich obsahuje | |
SK13196A3 (en) | Alkalicly substituted benzoylguanidines, manufacturing process thereof, their use as drug or diagnostic agent and drugs containing these compositions | |
RU2176638C2 (ru) | Замещенные инданилидинацетилгуанидины, способ их получения, применение в качестве лекарственных или диагностических средств и лекарственные средства, содержащие эти соединения | |
JP4039587B2 (ja) | 置換された1−ナフトイルグアニジン、その製法、医薬または診断剤としてのその使用およびそれを含有する医薬 | |
SK282351B6 (sk) | Orto-substituované benzoylguanidíny, spôsob ich výroby, ich použitie ako liečiva alebo diagnostického prostriedku a liečivo, ktoré ich obsahuje | |
MXPA97003922A (en) | 2-naftoilguanidinas substituted, procedure for preparation, its employment as a diagnostic occasive drug, as well as a medicinal product chelas conti | |
SK281753B6 (sk) | Orto-substituované benzoylguanidíny, spôsob ich výroby, ich použitie ako liečiva alebo diagnostika, ako aj liečivo, ktoré ich obsahuje | |
JPH09169719A (ja) | 置換されたベンゼンジカルボン酸ジグアニジド、それらの製法、医薬または診断剤としてのそれらの使用およびそれらを含有する医薬 | |
MXPA97003921A (en) | 1-naftoilguanidinas substitute, procedure for its preparation, its employment as a medicine or diagnostic agent, as well as a medication that the | |
MXPA97003871A (en) | Benzoilguanidinas bis-orto-replaced, procedure for its preparation, its employment as a diagnostic medicine or agent, as well as a medication that conti |