SK278736B6 - Perorálne aplikovateľná forma lieku na liečbu cent - Google Patents

Perorálne aplikovateľná forma lieku na liečbu cent Download PDF

Info

Publication number
SK278736B6
SK278736B6 SK3692-92A SK369292A SK278736B6 SK 278736 B6 SK278736 B6 SK 278736B6 SK 369292 A SK369292 A SK 369292A SK 278736 B6 SK278736 B6 SK 278736B6
Authority
SK
Slovakia
Prior art keywords
saponified polyvinyl
acetyl content
polyvinyl alcohol
residual acetyl
levodopa
Prior art date
Application number
SK3692-92A
Other languages
English (en)
Slovak (sk)
Other versions
SK369292A3 (en
Inventor
Udo Wenzel
G�Nther Weber
J�Rgen Metzner
Alfred D�Rr
Sabine Freitag
Frank-Ulrich Fl�ther
Frank-Michael Albert
Margit Haase
Edith Leistner
Original Assignee
Isis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Pharma Gmbh filed Critical Isis Pharma Gmbh
Publication of SK278736B6 publication Critical patent/SK278736B6/sk
Publication of SK369292A3 publication Critical patent/SK369292A3/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK3692-92A 1991-01-23 1992-01-23 Orally administerable drugs for the treatment of central dopamine deficiency conditions SK369292A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4101873A DE4101873C2 (de) 1991-01-23 1991-01-23 Peroral applizierbare Arzneiform zur Behandlung zentraler Dopaminmangelzustände
PCT/DE1992/000043 WO1992012710A1 (de) 1991-01-23 1992-01-23 Peroral applizierbare arzneiform zur behandlung zentraler dopaminmangelzustände

Publications (2)

Publication Number Publication Date
SK278736B6 true SK278736B6 (sk) 1998-02-04
SK369292A3 SK369292A3 (en) 1998-02-04

Family

ID=6423528

Family Applications (1)

Application Number Title Priority Date Filing Date
SK3692-92A SK369292A3 (en) 1991-01-23 1992-01-23 Orally administerable drugs for the treatment of central dopamine deficiency conditions

Country Status (22)

Country Link
US (1) US5532274A (ja)
EP (1) EP0568577B1 (ja)
JP (1) JP3382940B2 (ja)
AT (1) ATE147264T1 (ja)
AU (1) AU658171B2 (ja)
BG (1) BG61677B1 (ja)
CA (1) CA2101164C (ja)
CZ (1) CZ280847B6 (ja)
DE (2) DE4101873C2 (ja)
DK (1) DK0568577T3 (ja)
EE (1) EE03016B1 (ja)
ES (1) ES2098496T3 (ja)
FI (1) FI101040B (ja)
GR (1) GR3022993T3 (ja)
LT (1) LT3659B (ja)
LV (1) LV11103B (ja)
NO (1) NO304638B1 (ja)
RO (1) RO114737B1 (ja)
RU (1) RU2114619C1 (ja)
SK (1) SK369292A3 (ja)
UA (1) UA27848C2 (ja)
WO (1) WO1992012710A1 (ja)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6756056B2 (en) * 1997-04-08 2004-06-29 Alan A. Rubin Treatment of Parkinson's disease and related disorders by novel formulations of the combination carbidopa-levodopa
FI109453B (fi) * 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus
US6531153B2 (en) * 2001-05-29 2003-03-11 Drugtech Corporation Composition with sustained release of levodopa and carbidopa
CN1596100A (zh) * 2001-09-28 2005-03-16 麦克内尔-Ppc股份有限公司 可食用组合物及含可食用外壳的制剂
CA2501345A1 (en) * 2002-10-11 2004-04-22 Depomed Development, Ltd. Gastro-retentive levodopa delivery form
US8815950B2 (en) * 2003-08-29 2014-08-26 Janssen Biotech, Inc. Pharmaceutical compositions and method of using levodopa and carbidopa
ATE495739T1 (de) 2003-08-29 2011-02-15 Transform Pharmaceuticals Inc Pharmazeutische zusammensetzungen und verfahren zur verwendung von levodopa und carbidopa
ES2360759T3 (es) * 2003-08-29 2011-06-08 Centocor Ortho Biotech Inc. Composiciones farmacéuticas y procedimiento de utilización de la levodopa y de la carbidopa.
NZ560826A (en) * 2005-03-28 2009-06-26 Orexo Ab Composition comprising weak acid and particulate L-dopa useful in the treatment of parkinson's disease
WO2007002516A2 (en) * 2005-06-23 2007-01-04 Spherics, Inc. Improved dosage forms for movement disorder treatment
US20070275060A1 (en) * 2005-08-05 2007-11-29 Osmotica Costa Rica Sociedad Anonima Extended release solid pharmaceutical composition containing carbidopa and levodopa
US20080131492A1 (en) * 2006-06-23 2008-06-05 Spherics, Inc. Dosage forms for movement disorder treatment
WO2008079404A2 (en) * 2006-12-22 2008-07-03 Combinatorx, Incorporated Pharmaceutical compositions for treatment of parkinson's disease and related disorders
WO2009085306A1 (en) 2007-12-28 2009-07-09 Impax Laboratories, Inc. Controlled release formulations of levodopa and uses thereof
EP2233131A1 (en) * 2009-03-23 2010-09-29 Laboratorios Lesvi, S.L. Pharmaceutical composition containing levodopa, entacapone and carbidopa
KR20130009553A (ko) * 2011-07-15 2013-01-23 한미약품 주식회사 몬테루카스트 또는 이의 약학적으로 허용가능한 염 및 레보세티리진 또는 이의 약학적으로 허용가능한 염을 함유하는 캡슐 제제
EP3782614A1 (en) 2013-10-07 2021-02-24 Impax Laboratories, LLC Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
US10987313B2 (en) 2013-10-07 2021-04-27 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
JP7066351B2 (ja) * 2017-08-18 2022-05-13 大原薬品工業株式会社 良好な徐放性を有する、レボドパ含有小型化錠剤
JP6695013B1 (ja) * 2018-11-13 2020-05-20 日本酢ビ・ポバール株式会社 結合剤
EP3881839A4 (en) * 2018-11-13 2022-08-24 Japan Vam & Poval Co., Ltd. BINDER
US20210395507A1 (en) * 2018-11-13 2021-12-23 Japan Vam & Poval Co., Ltd. Binder
EP3881838A4 (en) * 2018-11-13 2022-08-17 Japan Vam & Poval Co., Ltd. ADHESIVE
WO2021205886A1 (ja) * 2020-04-10 2021-10-14 日本酢ビ・ポバール株式会社 結合剤
US11986449B2 (en) 2020-12-22 2024-05-21 Amneal Pharmaceuticals Llc Levodopa dosing regimen

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE631201C (de) * 1932-08-07 1936-06-16 Chemische Forschungs Gmbh Traegerstoff fuer Arzneimittel
DE748317C (de) * 1941-08-17 1944-12-19 Wacker Chemie Gmbh Verfahren zur Herstellung in Wasser zerfallender Faeden, Filme, Baender, Schlaeuche u. dgl. aus unvollstaendig verseiften Polyvinylalkoholen
US3584113A (en) * 1967-08-31 1971-06-08 Eisai Co Ltd Process for the production of medical preparations having sustained release of therapeutical effect
NL149372B (nl) * 1968-10-01 1976-05-17 Merck & Co Inc Werkwijze voor het bereiden van farmaceutische preparaten, alsmede de door toepassing daarvan verkregen gevormde voortbrengselen.
US3769424A (en) * 1970-10-01 1973-10-30 Merck & Co Inc Composition and method of treating dopamine deficiency in brain tissue
IE49522B1 (en) 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
DE3042916A1 (de) * 1979-06-01 1982-07-01 Joachim 7440 Nürtingen Dudzik Tablette
CA1218604A (en) * 1981-07-08 1987-03-03 Alec D. Keith Trinitroglycerol sustained release vehicles and preparations therefrom
US4424235A (en) * 1981-09-14 1984-01-03 Hoffmann-La Roche Inc. Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor
CH652025A5 (de) 1981-09-14 1985-10-31 Hoffmann La Roche Pharmazeutisches praeparat.
JPS5852219A (ja) * 1981-09-22 1983-03-28 Sumitomo Chem Co Ltd パ−キンソン病治療剤
EP0147780A3 (en) * 1984-01-03 1987-03-11 Merck & Co. Inc. Drug delivery device
US4927633A (en) * 1984-03-19 1990-05-22 Alza Corporation Dispenser for delivering drug to livestock
US4685918A (en) * 1985-02-01 1987-08-11 Merck & Co., Inc. Lipid osmotic pump
US4832957A (en) * 1987-12-11 1989-05-23 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
ZA889189B (en) * 1986-06-16 1989-08-30 Merck & Co Inc Controlled release combination of carbidopa/levodopa
US4983400A (en) * 1986-06-16 1991-01-08 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
NZ220599A (en) * 1986-06-16 1990-10-26 Merck & Co Inc Controlled release oral dosage formulation of carbidopa and levodopa
SE460947B (sv) * 1986-08-26 1989-12-11 Lejus Medical Ab En multiple-unit-dos komposition av l-dopa
US4940465A (en) * 1987-05-27 1990-07-10 Felix Theeuwes Dispenser comprising displaceable matrix with solid state properties
US4892778A (en) * 1987-05-27 1990-01-09 Alza Corporation Juxtaposed laminated arrangement
US4915949A (en) * 1987-07-13 1990-04-10 Alza Corporation Dispenser with movable matrix comprising a plurality of tiny pills
CA1331563C (en) * 1987-08-03 1994-08-23 Gaylen M. Zentner Device for the controlled release of drugs with donnan-like modulation by charged insoluble resins
AU608891B2 (en) * 1987-09-24 1991-04-18 Merck & Co., Inc. Solubility modulated drug delivery device
US4946686A (en) * 1987-09-24 1990-08-07 Merck & Co., Inc. Solubility modulated drug delivery system
DE3875716D1 (de) * 1987-12-31 1992-12-10 Asta Medica Ag Synergistische kombination von decarboxylasehemmern und l-dopa-pellets.
DE3841955A1 (de) * 1987-12-31 1989-07-13 Asta Pharma Ag Synergistische kombination von decarboxylasehemmern und l-dopa-pellets

Also Published As

Publication number Publication date
FI101040B (fi) 1998-04-15
RO114737B1 (ro) 1999-07-30
AU1186892A (en) 1992-08-27
NO932522D0 (no) 1993-07-09
DE4101873A1 (de) 1992-07-30
DE59207852D1 (de) 1997-02-20
LTIP555A (en) 1994-11-25
CA2101164C (fr) 2001-04-24
GR3022993T3 (en) 1997-07-30
ES2098496T3 (es) 1997-05-01
ATE147264T1 (de) 1997-01-15
BG61677B1 (bg) 1998-03-31
CA2101164A1 (fr) 1992-07-24
US5532274A (en) 1996-07-02
DE4101873C2 (de) 1993-12-09
EP0568577B1 (de) 1997-01-08
RU2114619C1 (ru) 1998-07-10
EE03016B1 (et) 1997-08-15
FI933304A (fi) 1993-07-22
UA27848C2 (uk) 2000-10-16
JPH06504543A (ja) 1994-05-26
EP0568577A1 (de) 1993-11-10
SK369292A3 (en) 1998-02-04
AU658171B2 (en) 1995-04-06
NO932522L (no) 1993-07-09
BG97894A (bg) 1994-04-29
WO1992012710A1 (de) 1992-08-06
NO304638B1 (no) 1999-01-25
FI933304A0 (fi) 1993-07-22
CZ280847B6 (cs) 1996-04-17
LT3659B (en) 1996-01-25
CZ369292A3 (en) 1993-09-15
JP3382940B2 (ja) 2003-03-04
DK0568577T3 (da) 1997-06-30
LV11103A (lv) 1996-04-20
LV11103B (en) 1996-06-20

Similar Documents

Publication Publication Date Title
SK278736B6 (sk) Perorálne aplikovateľná forma lieku na liečbu cent
KR101406767B1 (ko) 프라미펙솔 또는 약제학적으로 허용되는 이의 염을함유하는 연장 방출성 정제 제형, 이의 제조방법 및 이의용도
US6607750B2 (en) Directly compressible acetaminophen compositions
US7351429B1 (en) Oral solid preparation
EP2058010B1 (en) Pharmaceutical composition
EP2939662B1 (en) Pharmaceutical composition comprising temozolomide with improved stability and process for manufacturing the same
EP1810676B1 (en) Levetiracetam formulations and methods for their manufacture
US11413295B2 (en) Oral preparation of obeticholic acid
JPH10194969A (ja) 錠剤組成物
JPH02500747A (ja) 医薬組成物
JP6895779B2 (ja) アジルサルタン含有固形医薬組成物
SK282506B6 (sk) Tableta obsahujúca paracetamol a domperidon
US5624960A (en) Orally administrable drugs for the treatment of central dopamine deficiency conditions
KR20040006887A (ko) 아세트아미노펜을 함유하는 제어방출성의 경구용 제제
WO2006123213A1 (en) Modified release formulations of gliclazide
JP2007161706A (ja) 安中散含有錠剤
JP2022544167A (ja) ニトロキソリンを含む医薬組成物、ニトロキソリン経口固形錠剤、その調製方法、及びその使用
JP4063386B2 (ja) 速放性経口医薬品組成物
WO2022222886A1 (zh) 一种噁拉戈利钠组合物
CA1334933C (en) Pharmaceutical composition and process for its preparation
WO2000071117A1 (fr) Compositions medicinales a liberation immediate pour administration orale
CA3160779A1 (en) Pharmaceutical composition comprising eltrombopag bis(monoethanolamine)
WO2020122244A1 (ja) 錠剤及びその製造方法
KR20220006776A (ko) 다이아미노피리미딘 유도체 또는 이의 약학적으로 허용가능한 염을 포함하는 약학 조성물 및 이의 제조방법
WO2024121413A1 (en) Formulation comprising edoxaban and preparation thereof