SK278283B6 - Substituted piperidinecarboxamides, method of their manufacture, pharmaceutical drugs containing them and their application - Google Patents

Substituted piperidinecarboxamides, method of their manufacture, pharmaceutical drugs containing them and their application Download PDF

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Publication number
SK278283B6
SK278283B6 SK6581-90A SK658190A SK278283B6 SK 278283 B6 SK278283 B6 SK 278283B6 SK 658190 A SK658190 A SK 658190A SK 278283 B6 SK278283 B6 SK 278283B6
Authority
SK
Slovakia
Prior art keywords
formula
substituted
compounds
group
piperidinecarboxamide
Prior art date
Application number
SK6581-90A
Other languages
English (en)
Slovak (sk)
Other versions
SK658190A3 (en
Inventor
Anna-Lena Ask
Rune V Sandberg
Original Assignee
Anna-Lena Ask
Sandberg Rune V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anna-Lena Ask, Sandberg Rune V. filed Critical Anna-Lena Ask
Publication of SK658190A3 publication Critical patent/SK658190A3/sk
Publication of SK278283B6 publication Critical patent/SK278283B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cosmetics (AREA)
SK6581-90A 1989-12-21 1990-12-21 Substituted piperidinecarboxamides, method of their manufacture, pharmaceutical drugs containing them and their application SK278283B6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8904298A SE8904298D0 (sv) 1989-12-21 1989-12-21 New compounds

Publications (2)

Publication Number Publication Date
SK658190A3 SK658190A3 (en) 1996-08-07
SK278283B6 true SK278283B6 (en) 1996-08-07

Family

ID=20377821

Family Applications (1)

Application Number Title Priority Date Filing Date
SK6581-90A SK278283B6 (en) 1989-12-21 1990-12-21 Substituted piperidinecarboxamides, method of their manufacture, pharmaceutical drugs containing them and their application

Country Status (40)

Country Link
US (2) US5227389A (fr)
EP (1) EP0506778B1 (fr)
JP (1) JP2656152B2 (fr)
KR (1) KR0179382B1 (fr)
CN (1) CN1037841C (fr)
AT (1) ATE138650T1 (fr)
AU (1) AU647068B2 (fr)
BG (1) BG60912B1 (fr)
BR (1) BR1100379A (fr)
CA (1) CA2069608C (fr)
CZ (1) CZ278035B6 (fr)
DE (1) DE69027221T2 (fr)
DK (1) DK0506778T3 (fr)
DZ (1) DZ1468A1 (fr)
EG (1) EG19361A (fr)
ES (1) ES2087280T3 (fr)
FI (1) FI100881B (fr)
HK (1) HK22997A (fr)
HR (1) HRP920591B1 (fr)
HU (1) HU213110B (fr)
IE (1) IE74855B1 (fr)
IL (1) IL96636A (fr)
IS (1) IS1664B (fr)
LT (1) LT4005B (fr)
LV (2) LV10949B (fr)
NO (1) NO178858C (fr)
NZ (1) NZ236293A (fr)
PL (1) PL163591B1 (fr)
PT (1) PT96303B (fr)
RO (1) RO112864B1 (fr)
RU (1) RU2039043C1 (fr)
SA (1) SA91110209B1 (fr)
SE (1) SE8904298D0 (fr)
SG (1) SG46413A1 (fr)
SI (1) SI9012346B (fr)
SK (1) SK278283B6 (fr)
UA (1) UA26403A (fr)
WO (1) WO1991009845A1 (fr)
YU (1) YU48086B (fr)
ZA (1) ZA909903B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3916092B2 (ja) * 1993-09-17 2007-05-16 杏林製薬株式会社 イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬
SE9400447D0 (sv) * 1994-02-11 1994-02-11 Astra Ab New compounds
SE9404438D0 (sv) * 1994-12-21 1994-12-21 Astra Ab New process
US5931809A (en) 1995-07-14 1999-08-03 Depotech Corporation Epidural administration of therapeutic compounds with sustained rate of release
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
US20020102291A1 (en) * 1997-12-15 2002-08-01 Noven Pharmaceuticals, Inc. Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate
JP4280073B2 (ja) * 2001-04-12 2009-06-17 ファーマコペイア ドラッグ ディスカバリー， インコーポレイテッド Ｍｃｈアンタゴニストとして使用されるアリールピペリジンおよびビアリールピペリジン
JP2006511554A (ja) * 2002-12-13 2006-04-06 スミスクライン ビーチャム コーポレーション Ｃｃｒ５アンタゴニストとしてのピペリジン誘導体
WO2008045564A2 (fr) * 2006-10-12 2008-04-17 Epix Delaware, Inc. Composés de carboxamide et leur utilisation
RU2010128543A (ru) 2007-12-11 2012-01-20 Сайтопатфайндер, Инк. (Jp) Карбоксамидные соединения и их применение в качестве агонистов хемокиновых рецепторов
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
EP3914246A1 (fr) 2019-01-22 2021-12-01 ICM (Institut du Cerveau et de la Moelle Épinière) Anesthésique local pour le traitement de symptômes neurologiques résultant de dysfonctionnements cérébraux

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE96980C1 (fr)
US2486796A (en) * 1943-06-25 1949-11-01 Ciba Pharm Prod Inc Esters of 1-alkyl-4-hydroxyphenylpiperidyl-4-ketones
US3334106A (en) * 1964-10-20 1967-08-01 Aldrich Chem Co Inc N(aryl)n(hydrocarbyl)-omega-(4-phenyl-4-piperidinocarbonylheteroamine) alkanoamide
US3539580A (en) * 1967-06-26 1970-11-10 Janssen Pharm 4-aryl-4-aminoalkoxy-piperidines
CH501622A (de) * 1968-12-20 1971-01-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Piperidinderivaten
US3737538A (en) * 1968-12-30 1973-06-05 Ciba Geigy Corp Antitussive compositions and method with isonipecotic acid derivatives
FR2156470A2 (en) * 1971-10-21 1973-06-01 Synthelabo 1-(3,3-diphenyl-1-propyl)-4-aryl-piperidines - as analgesics spasmolytic and anti-tussive agents
ZA899436B (en) * 1988-12-12 1990-08-29 Ciba Geigy Piperidine derivatives
US5100903A (en) * 1989-05-12 1992-03-31 Anaquest, Inc. N-aryl-n-(1-substituted-3-alkoxy-4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds

Also Published As

Publication number Publication date
YU234690A (sh) 1993-10-20
DE69027221T2 (de) 1996-10-10
DE69027221D1 (de) 1996-07-04
FI922806A0 (fi) 1992-06-17
NO922380D0 (no) 1992-06-17
ES2087280T3 (es) 1996-07-16
HU9202044D0 (en) 1992-09-28
HK22997A (en) 1997-02-27
BG60912B1 (bg) 1996-06-28
FI922806A (fi) 1992-06-17
LV10949A (lv) 1995-12-20
IL96636A (en) 1994-11-28
CA2069608A1 (fr) 1991-06-22
SI9012346B (sl) 1999-08-31
PL163591B1 (pl) 1994-04-29
SE8904298D0 (sv) 1989-12-21
HRP920591A2 (en) 1997-08-31
US5360805A (en) 1994-11-01
ZA909903B (en) 1991-08-28
LV5766B4 (lv) 1997-06-20
LV5766A4 (lv) 1996-12-20
RU2039043C1 (ru) 1995-07-09
PT96303B (pt) 1998-07-31
HRP920591B1 (en) 1998-12-31
NO178858C (no) 1996-06-19
HU213110B (en) 1997-02-28
AU6978391A (en) 1991-07-24
YU48086B (sh) 1997-01-08
CZ278035B6 (en) 1993-07-14
BG96513A (bg) 1993-12-24
US5227389A (en) 1993-07-13
SK658190A3 (en) 1996-08-07
WO1991009845A1 (fr) 1991-07-11
NZ236293A (en) 1992-10-28
IL96636A0 (en) 1991-09-16
KR0179382B1 (ko) 1999-03-20
CN1053605A (zh) 1991-08-07
PL288409A1 (en) 1991-12-02
AU647068B2 (en) 1994-03-17
LT4005B (en) 1996-07-25
DK0506778T3 (da) 1996-10-07
KR927003531A (ko) 1992-12-18
SG46413A1 (en) 1998-02-20
IE74855B1 (en) 1997-08-13
RO112864B1 (ro) 1998-01-30
EP0506778A1 (fr) 1992-10-07
PT96303A (pt) 1991-09-30
CZ658190A3 (en) 1993-01-13
JPH05502869A (ja) 1993-05-20
IE904534A1 (en) 1991-07-03
CA2069608C (fr) 2001-07-10
SA91110209B1 (ar) 2004-05-08
JP2656152B2 (ja) 1997-09-24
NO178858B (no) 1996-03-11
DZ1468A1 (fr) 2004-09-13
IS3659A7 (is) 1991-06-22
SI9012346A (sl) 1998-08-31
BR1100379A (pt) 1999-12-07
FI100881B (fi) 1998-03-13
ATE138650T1 (de) 1996-06-15
HUT64518A (en) 1994-01-28
LTIP1731A (en) 1995-07-25
EG19361A (en) 1994-12-30
EP0506778B1 (fr) 1996-05-29
IS1664B (is) 1997-07-04
NO922380L (no) 1992-06-17
LV10949B (en) 1996-06-20
CN1037841C (zh) 1998-03-25
UA26403A (uk) 1999-08-30

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