SK15762001A3 - Rekombinantný doštičkový kolagénový receptor glykoproteínu VI a jeho farmaceutické použitie - Google Patents
Rekombinantný doštičkový kolagénový receptor glykoproteínu VI a jeho farmaceutické použitie Download PDFInfo
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- SK15762001A3 SK15762001A3 SK1576-2001A SK15762001A SK15762001A3 SK 15762001 A3 SK15762001 A3 SK 15762001A3 SK 15762001 A SK15762001 A SK 15762001A SK 15762001 A3 SK15762001 A3 SK 15762001A3
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- Prior art keywords
- gpvi
- platelet
- collagen
- sequence
- recombinant
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/018—Platelets
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
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- G01N2800/22—Haematology
- G01N2800/222—Platelet disorders
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
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- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
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- Hematology (AREA)
- Biophysics (AREA)
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- Biomedical Technology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99109094 | 1999-05-07 | ||
| PCT/EP2000/003683 WO2000068377A1 (en) | 1999-05-07 | 2000-04-25 | Recombinant platelet collagen receptor glycoprotein vi and its pharmaceutical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK15762001A3 true SK15762001A3 (sk) | 2002-04-04 |
Family
ID=8238132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1576-2001A SK15762001A3 (sk) | 1999-05-07 | 2000-04-25 | Rekombinantný doštičkový kolagénový receptor glykoproteínu VI a jeho farmaceutické použitie |
Country Status (26)
| Country | Link |
|---|---|
| US (5) | US7928066B1 (de) |
| EP (3) | EP1942186B1 (de) |
| JP (2) | JP5480457B2 (de) |
| KR (1) | KR100703592B1 (de) |
| CN (1) | CN1253569C (de) |
| AR (1) | AR023848A1 (de) |
| AT (1) | ATE393223T1 (de) |
| AU (1) | AU775952B2 (de) |
| BR (1) | BRPI0010325B1 (de) |
| CA (1) | CA2372515C (de) |
| CY (2) | CY1108190T1 (de) |
| CZ (1) | CZ302693B6 (de) |
| DE (1) | DE60038675T2 (de) |
| DK (2) | DK1177289T3 (de) |
| ES (2) | ES2534652T3 (de) |
| HK (1) | HK1045714B (de) |
| HU (1) | HUP0201049A2 (de) |
| MX (1) | MXPA01011274A (de) |
| NO (1) | NO333408B1 (de) |
| PL (1) | PL204449B1 (de) |
| PT (2) | PT2341141E (de) |
| RU (1) | RU2287580C2 (de) |
| SI (1) | SI1177289T1 (de) |
| SK (1) | SK15762001A3 (de) |
| WO (1) | WO2000068377A1 (de) |
| ZA (1) | ZA200110071B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK15762001A3 (sk) | 1999-05-07 | 2002-04-04 | Merck Patent Gmbh | Rekombinantný doštičkový kolagénový receptor glykoproteínu VI a jeho farmaceutické použitie |
| US7291714B1 (en) | 1999-06-30 | 2007-11-06 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
| US6245527B1 (en) | 1999-06-30 | 2001-06-12 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof |
| US20040001826A1 (en) | 1999-06-30 | 2004-01-01 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
| AU7097400A (en) * | 1999-09-01 | 2001-03-26 | Otsuka Pharmaceutical Co., Ltd. | Platelet membrane glycoprotein vi (gpvi) dna and protein sequences, and uses thereof |
| EP1224942A1 (de) * | 2001-01-23 | 2002-07-24 | Bernhard Dr. Nieswandt | Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases |
| EP1406929A2 (de) * | 2001-07-18 | 2004-04-14 | MERCK PATENT GmbH | Glycoprotein vi fusionproteine |
| US7531178B2 (en) | 2002-06-07 | 2009-05-12 | Trigen Gmbh | Immunoadhesin comprising a glycoprotein VI domain |
| EP1369128A1 (de) | 2002-06-07 | 2003-12-10 | Procorde GmbH | Glycoprotein VI Inhibitoren und deren therapeutische Verwendung |
| US20070071744A1 (en) | 2002-06-07 | 2007-03-29 | Gotz Munch | Agents which bind to epitopes of glycoprotein VI |
| DE102004017295A1 (de) * | 2004-04-05 | 2005-11-03 | Zlb Behring Gmbh | Verbindungen, welche die Entfernung von Rezeptoren von Zelllmembranen bewirken oder verhindern, und Verfahren zu ihrem Nachweis |
| CN1964990B (zh) | 2004-04-29 | 2012-12-12 | 大冢制药株式会社 | 糖蛋白ⅵ特异的抗体以及生产这些抗体的方法 |
| US7645592B2 (en) | 2004-04-29 | 2010-01-12 | Otsuka Pharmaceutical Co., Ltd. | Glycoprotein VI antibodies and methods of use thereof |
| WO2006117910A1 (ja) | 2005-04-28 | 2006-11-09 | Mochida Pharmaceutical Co., Ltd. | 抗血小板膜糖蛋白質ⅵモノクローナル抗体 |
| RU2010121878A (ru) * | 2007-10-31 | 2011-12-10 | Оцука Фармасьютикал Ко., Лтд. (Jp) | Применения ингибитора гликопротеина vi (gpvi) |
| EP2694709B1 (de) | 2011-04-08 | 2016-09-14 | Prognosys Biosciences, Inc. | Peptidkonstrukte und testsysteme dafür |
| EP3184544A1 (de) * | 2015-12-23 | 2017-06-28 | Julius-Maximilians-Universität Würzburg | Glycoprotein-v-inhibitoren zur verwendung als koagulansien |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT662088E (pt) | 1993-07-01 | 2002-06-28 | Merck Patent Gmbh | Inibidor da agregacao de plaquetas estimulada por colagenio |
| AU701576B2 (en) * | 1993-10-22 | 1999-02-04 | Trigen Limited | Platelet-derived growth factor analogues |
| AU5927398A (en) * | 1997-01-21 | 1998-08-07 | Human Genome Sciences, Inc. | Fc receptors and polypeptides |
| CA2250291A1 (en) * | 1997-01-29 | 1998-07-30 | Toray Industries Inc. | Chimeric proteins, their heterodimer complexes, and platelet substitutes |
| SK15762001A3 (sk) | 1999-05-07 | 2002-04-04 | Merck Patent Gmbh | Rekombinantný doštičkový kolagénový receptor glykoproteínu VI a jeho farmaceutické použitie |
| US7291714B1 (en) * | 1999-06-30 | 2007-11-06 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
| US20040001826A1 (en) | 1999-06-30 | 2004-01-01 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
| US6245527B1 (en) * | 1999-06-30 | 2001-06-12 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof |
| AU7097400A (en) * | 1999-09-01 | 2001-03-26 | Otsuka Pharmaceutical Co., Ltd. | Platelet membrane glycoprotein vi (gpvi) dna and protein sequences, and uses thereof |
| EP1406929A2 (de) | 2001-07-18 | 2004-04-14 | MERCK PATENT GmbH | Glycoprotein vi fusionproteine |
| EP1538165A1 (de) | 2003-12-03 | 2005-06-08 | Procorde GmbH | Glycoprotein VI Inhibitoren auf der Basis des monoklonalen Antikörpers hgp 5c4 |
-
2000
- 2000-04-25 SK SK1576-2001A patent/SK15762001A3/sk unknown
- 2000-04-25 DK DK00927035T patent/DK1177289T3/da active
- 2000-04-25 KR KR1020017014164A patent/KR100703592B1/ko not_active IP Right Cessation
- 2000-04-25 DK DK11001216T patent/DK2341141T3/en active
- 2000-04-25 US US09/959,802 patent/US7928066B1/en not_active Expired - Fee Related
- 2000-04-25 ES ES11001216.8T patent/ES2534652T3/es not_active Expired - Lifetime
- 2000-04-25 HU HU0201049A patent/HUP0201049A2/hu unknown
- 2000-04-25 EP EP08004264.1A patent/EP1942186B1/de not_active Expired - Lifetime
- 2000-04-25 CA CA2372515A patent/CA2372515C/en not_active Expired - Fee Related
- 2000-04-25 CZ CZ20013989A patent/CZ302693B6/cs not_active IP Right Cessation
- 2000-04-25 PL PL351437A patent/PL204449B1/pl unknown
- 2000-04-25 SI SI200030996T patent/SI1177289T1/sl unknown
- 2000-04-25 JP JP2000616343A patent/JP5480457B2/ja not_active Expired - Fee Related
- 2000-04-25 PT PT110012168T patent/PT2341141E/pt unknown
- 2000-04-25 EP EP11001216.8A patent/EP2341141B1/de not_active Expired - Lifetime
- 2000-04-25 PT PT00927035T patent/PT1177289E/pt unknown
- 2000-04-25 CN CNB008072922A patent/CN1253569C/zh not_active Expired - Fee Related
- 2000-04-25 MX MXPA01011274A patent/MXPA01011274A/es active IP Right Grant
- 2000-04-25 DE DE60038675T patent/DE60038675T2/de not_active Expired - Lifetime
- 2000-04-25 BR BRPI0010325A patent/BRPI0010325B1/pt not_active IP Right Cessation
- 2000-04-25 ES ES00927035T patent/ES2304347T3/es not_active Expired - Lifetime
- 2000-04-25 RU RU2001132140/13A patent/RU2287580C2/ru not_active IP Right Cessation
- 2000-04-25 AU AU45555/00A patent/AU775952B2/en not_active Ceased
- 2000-04-25 EP EP00927035A patent/EP1177289B1/de not_active Expired - Lifetime
- 2000-04-25 WO PCT/EP2000/003683 patent/WO2000068377A1/en active IP Right Grant
- 2000-04-25 AT AT00927035T patent/ATE393223T1/de active
- 2000-05-04 AR ARP000102136A patent/AR023848A1/es unknown
-
2001
- 2001-11-06 NO NO20015420A patent/NO333408B1/no not_active IP Right Cessation
- 2001-12-06 ZA ZA200110071A patent/ZA200110071B/xx unknown
-
2002
- 2002-09-26 HK HK02107061.7A patent/HK1045714B/zh not_active IP Right Cessation
-
2007
- 2007-03-21 US US11/689,392 patent/US20070172480A1/en not_active Abandoned
- 2007-03-21 US US11/689,385 patent/US8198030B2/en not_active Expired - Lifetime
-
2008
- 2008-07-11 CY CY20081100731T patent/CY1108190T1/el unknown
-
2010
- 2010-12-20 JP JP2010283409A patent/JP5554696B2/ja not_active Expired - Fee Related
-
2011
- 2011-03-11 US US13/046,210 patent/US8278430B2/en not_active Expired - Lifetime
-
2015
- 2015-04-09 CY CY20151100344T patent/CY1116336T1/el unknown
-
2016
- 2016-03-08 US US15/064,157 patent/US20160207976A1/en not_active Abandoned
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