SK135493A3 - Pharmacological effective compounds, the method of their preparation and pharmaceutical compositions, which these compounds contain - Google Patents

Pharmacological effective compounds, the method of their preparation and pharmaceutical compositions, which these compounds contain Download PDF

Info

Publication number
SK135493A3
SK135493A3 SK1354-93A SK135493A SK135493A3 SK 135493 A3 SK135493 A3 SK 135493A3 SK 135493 A SK135493 A SK 135493A SK 135493 A3 SK135493 A3 SK 135493A3
Authority
SK
Slovakia
Prior art keywords
group
compound
formula
configuration
hydroxy
Prior art date
Application number
SK1354-93A
Other languages
English (en)
Slovak (sk)
Inventor
Michael M Dreyfuss
Albert Leutwiler
Andrew R Mackenzie
Jorg Schnyder
Rene P Traber
Henri Mattes
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SK135493A3 publication Critical patent/SK135493A3/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Botany (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
SK1354-93A 1992-12-04 1993-12-02 Pharmacological effective compounds, the method of their preparation and pharmaceutical compositions, which these compounds contain SK135493A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929225396A GB9225396D0 (en) 1992-12-04 1992-12-04 Improvements in or relating to organic compounds

Publications (1)

Publication Number Publication Date
SK135493A3 true SK135493A3 (en) 1994-08-10

Family

ID=10726140

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1354-93A SK135493A3 (en) 1992-12-04 1993-12-02 Pharmacological effective compounds, the method of their preparation and pharmaceutical compositions, which these compounds contain

Country Status (18)

Country Link
EP (1) EP0606044A1 (enExample)
JP (1) JPH06228122A (enExample)
KR (1) KR940014377A (enExample)
CN (1) CN1095417A (enExample)
AU (1) AU5211293A (enExample)
CA (1) CA2110553A1 (enExample)
CZ (1) CZ261493A3 (enExample)
FI (1) FI935409A7 (enExample)
GB (1) GB9225396D0 (enExample)
HU (1) HUT65910A (enExample)
IL (1) IL107838A0 (enExample)
MX (1) MX9307608A (enExample)
NO (1) NO934372L (enExample)
NZ (1) NZ250344A (enExample)
PL (1) PL301281A1 (enExample)
SK (1) SK135493A3 (enExample)
TW (1) TW258736B (enExample)
ZA (1) ZA939088B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4228328C2 (de) * 1992-08-26 1999-02-11 Agie Sa Maschine und Verfahren zum funkenerosiven Drahtschneiden mit einer im Querschnitt verformten Drahtelektrode
US5795910A (en) * 1994-10-28 1998-08-18 Cor Therapeutics, Inc. Method and compositions for inhibiting protein kinases
US5731343A (en) * 1995-02-24 1998-03-24 The Scripps Research Institute Method of use of radicicol for treatment of immunopathological disorders
NZ311790A (en) * 1995-04-26 1999-04-29 Kyowa Hakko Kogyo Kk Radicicol derivatives
CA2356622A1 (en) * 1998-12-24 2000-07-06 Novation Pharmaceuticals Inc. Compounds which affect mrna stability and uses therefor
AU2001286768A1 (en) 2000-08-25 2002-03-04 Sloan-Kettering Institute For Cancer Research Novel macrocycles and uses thereof
JP2004292315A (ja) * 2000-12-14 2004-10-21 Chugai Pharmaceut Co Ltd Ｔａｋ１阻害剤
JP2004292314A (ja) * 2000-12-14 2004-10-21 Chugai Pharmaceut Co Ltd ケラチノサイト増殖抑制剤
GB0112522D0 (en) * 2001-05-23 2001-07-11 Ici Plc Catalytic process
ES2555307T3 (es) * 2002-03-08 2015-12-30 Eisai R&D Management Co., Ltd. Compuestos macrocíclicos útiles como agentes farmacéuticos
US7915306B2 (en) * 2002-03-08 2011-03-29 Eisai Co., Ltd. Macrocyclic compounds useful as pharmaceuticals
EP1498104A4 (en) * 2002-04-17 2006-05-03 Taisho Pharmaceutical Co Ltd TONIC PRODUCT FOR HAIR GROWTH
CA2581375A1 (en) * 2004-09-27 2006-04-06 Kosan Biosciences Incorporated Specific kinase inhibitors
US7601852B2 (en) 2006-05-11 2009-10-13 Kosan Biosciences Incorporated Macrocyclic kinase inhibitors
AU2008279027B8 (en) 2007-07-25 2014-03-06 Eisai R & D Management Co., Ltd. Multikinase inhibitors for use in the treatment of cancer
WO2009058908A2 (en) 2007-10-29 2009-05-07 Eisai R & D Management Co., Ltd. Methods for prognosing the ability of a zearalenone analog compound to treat cancer
CN101889006B (zh) 2007-12-07 2013-09-04 卫材R&D管理株式会社 用于制备玉米赤霉烯酮大环内酯类似物的中间物和方法
JP6265583B2 (ja) 2008-10-17 2018-01-24 ウィスコンシン アルムニ リサーチ ファンデイション 生理活性アルファベータペプチドを作製する方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3196019A (en) * 1964-04-06 1965-07-20 Purdue Research Foundation Anabolic and estrogenic compound and process of making

Also Published As

Publication number Publication date
AU5211293A (en) 1994-06-16
IL107838A0 (en) 1994-04-12
FI935409L (fi) 1994-06-05
FI935409A7 (fi) 1994-06-05
JPH06228122A (ja) 1994-08-16
NO934372D0 (no) 1993-12-02
PL301281A1 (en) 1994-06-13
KR940014377A (ko) 1994-07-18
HUT65910A (en) 1994-07-28
CA2110553A1 (en) 1994-06-05
ZA939088B (en) 1995-06-05
NO934372L (no) 1994-06-06
TW258736B (enExample) 1995-10-01
EP0606044A1 (en) 1994-07-13
CZ261493A3 (en) 1994-07-13
GB9225396D0 (en) 1993-01-27
FI935409A0 (fi) 1993-12-02
HU9303444D0 (en) 1994-04-28
MX9307608A (es) 1995-01-31
CN1095417A (zh) 1994-11-23
NZ250344A (en) 1995-10-26

Similar Documents

Publication Publication Date Title
SK135493A3 (en) Pharmacological effective compounds, the method of their preparation and pharmaceutical compositions, which these compounds contain
JP2003530391A (ja) ペルシキニン、その製造方法および医薬としてのその使用
HU182069B (en) Process for preparing monacoline k, a compound with antihypercholesteremic activity
EP0099692A1 (en) New furanone derivatives, process for the preparation thereof and use thereof
JPH04217986A (ja) 抗高コレステロール血症薬
RU1826970C (ru) Способ получени производных пептидов WS-9326 А
US5079263A (en) Manumycin derivatives and the use thereof
EP0804186B1 (en) Indole diterpene alkaloid compounds
US5712306A (en) Physiologically active substances PF1092A, PF1092B and PF1092C, and contraceptives and anticancer drugs containing the same as active ingredients
JP5038572B2 (ja) シクリポスチン類、その製造方法およびその使用方法
US5338758A (en) Bicyclic diterpene PAF antagonist compounds
US3701787A (en) Preparation of 5,6-dihydro-5-hydroxy-6-propenyl-2-pyrone by fermentation and derivatives thereof
EP0057724A1 (en) New metabolites, processes for their production and their use
EP0866801B1 (en) Cyclopeptolides
JPH0256423A (ja) ナフトピラン誘導体およびその用途
US6380257B1 (en) Aromatic di-keto derivatives, processes for their production and their use as a pharmaceutical
US3842092A (en) Sesquicillin
JPH02129199A (ja) エライオフイリンのエノールエーテル類およびその製法
JP2002518057A (ja) ムンバイスタチン、その製造法およびその医薬としての使用
SK11202003A3 (sk) Použitie tiolutín-dioxidu a jeho derivátov na prípravu liečiva, spôsob jeho prípravy pomocou mikroorganizmu a mikroorganizmus Nocardiopsis species ST 100692, DSM 13834
US4956383A (en) Antifungal triacetylenic dioxolone from Microbispora sp. SCC 1438, ATCC 53620
US5143832A (en) ATCC 53620 production of a triacetylenic dioxolone with Microbispora sp. SCC 1438
KR100322240B1 (ko) 페니실리움 속(Ｐｅｎｉｃｉｌｌｉｕｍ ｓｐ.)Ｆ70614(ＫＣＴＣ 8918Ｐ)와 α-글루코시다제 저해제
KR0130473B1 (ko) 새로운 항생물질, 베나노마이신 a와 b 및 덱실오실베나노마이신 b와 이들의 제조 방법과 용도
EP1080220A1 (en) New biotechnological process for preparing hydroxylated ml-236b derivatives, known as m-4 and m-4', and analogues thereof