JPH06228122A - 有機化合物に関する改良 - Google Patents

有機化合物に関する改良

Info

Publication number
JPH06228122A
JPH06228122A JP5303866A JP30386693A JPH06228122A JP H06228122 A JPH06228122 A JP H06228122A JP 5303866 A JP5303866 A JP 5303866A JP 30386693 A JP30386693 A JP 30386693A JP H06228122 A JPH06228122 A JP H06228122A
Authority
JP
Japan
Prior art keywords
formula
compound
cis
trans
choh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5303866A
Other languages
English (en)
Japanese (ja)
Inventor
Michael Morris Dreyfuss
マイケル・モリス・ドレイフユス
Albert Leutwiler
アルベルト・ロイトヴィラー
Andrew Roland Mackenzie
アンドリュー・ローランド・マッケンジー
Joerg Schnyder
イェルク・シュナイダー
Rene Paul Traber
レネ・パウル・トラーバー
Henri Mattes
アンリ・マット
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of JPH06228122A publication Critical patent/JPH06228122A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
JP5303866A 1992-12-04 1993-12-03 有機化合物に関する改良 Pending JPH06228122A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929225396A GB9225396D0 (en) 1992-12-04 1992-12-04 Improvements in or relating to organic compounds
GB9225396 1992-12-04

Publications (1)

Publication Number Publication Date
JPH06228122A true JPH06228122A (ja) 1994-08-16

Family

ID=10726140

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5303866A Pending JPH06228122A (ja) 1992-12-04 1993-12-03 有機化合物に関する改良

Country Status (18)

Country Link
EP (1) EP0606044A1 (enExample)
JP (1) JPH06228122A (enExample)
KR (1) KR940014377A (enExample)
CN (1) CN1095417A (enExample)
AU (1) AU5211293A (enExample)
CA (1) CA2110553A1 (enExample)
CZ (1) CZ261493A3 (enExample)
FI (1) FI935409A7 (enExample)
GB (1) GB9225396D0 (enExample)
HU (1) HUT65910A (enExample)
IL (1) IL107838A0 (enExample)
MX (1) MX9307608A (enExample)
NO (1) NO934372L (enExample)
NZ (1) NZ250344A (enExample)
PL (1) PL301281A1 (enExample)
SK (1) SK135493A3 (enExample)
TW (1) TW258736B (enExample)
ZA (1) ZA939088B (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4228328A1 (de) * 1992-08-26 1994-03-10 Agie Ag Ind Elektronik Elektroerosions-Schneidvorrichtung, Elektroerosions-Schneidverfahren und Erodierdraht
JP2005519954A (ja) * 2002-03-08 2005-07-07 エーザイ株式会社 医薬として有用な大環状化合物
JP2008514635A (ja) * 2004-09-27 2008-05-08 コーザン バイオサイエンシス インコーポレイテッド 特異的キナーゼ阻害剤
US7915306B2 (en) 2002-03-08 2011-03-29 Eisai Co., Ltd. Macrocyclic compounds useful as pharmaceuticals
US8609640B2 (en) 2007-07-25 2013-12-17 Eisai, Inc. Multikinase inhibitors for use in the treatment of cancer

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795910A (en) * 1994-10-28 1998-08-18 Cor Therapeutics, Inc. Method and compositions for inhibiting protein kinases
US5731343A (en) * 1995-02-24 1998-03-24 The Scripps Research Institute Method of use of radicicol for treatment of immunopathological disorders
JP3938936B2 (ja) * 1995-04-26 2007-06-27 協和醗酵工業株式会社 ラディシコール誘導体
JP2002533389A (ja) * 1998-12-24 2002-10-08 ノーベーション ファーマシューティカルズ インコーポレーテッド ｍＲＮＡ安定性に影響する化合物およびそのための使用
EP1315732B1 (en) 2000-08-25 2006-06-07 Sloan-Kettering Institute For Cancer Research Radicicol and monocillin and their analogues and uses thereof
JP2004292315A (ja) * 2000-12-14 2004-10-21 Chugai Pharmaceut Co Ltd Ｔａｋ１阻害剤
JP2004292314A (ja) * 2000-12-14 2004-10-21 Chugai Pharmaceut Co Ltd ケラチノサイト増殖抑制剤
GB0112522D0 (en) * 2001-05-23 2001-07-11 Ici Plc Catalytic process
CN1652743A (zh) * 2002-04-17 2005-08-10 大正制药株式会社 毛发生长补剂
US7601852B2 (en) 2006-05-11 2009-10-13 Kosan Biosciences Incorporated Macrocyclic kinase inhibitors
JP5564431B2 (ja) 2007-10-29 2014-07-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 ゼアラレノンアナログ化合物ががんを処置する能力を予測する方法
RU2478630C2 (ru) 2007-12-07 2013-04-10 ЭЙСАН Ар ЭНД Ди МЕНЕДЖМЕНТ КО., ЛТД. Промежуточные соединения и способы получения зеараленоновых макролидных аналогов
CA2740873C (en) 2008-10-17 2019-09-10 Wisconsin Alumni Research Foundation Method of making biologically active alpha-beta peptides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3196019A (en) * 1964-04-06 1965-07-20 Purdue Research Foundation Anabolic and estrogenic compound and process of making

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4228328A1 (de) * 1992-08-26 1994-03-10 Agie Ag Ind Elektronik Elektroerosions-Schneidvorrichtung, Elektroerosions-Schneidverfahren und Erodierdraht
DE4228328C2 (de) * 1992-08-26 1999-02-11 Agie Sa Maschine und Verfahren zum funkenerosiven Drahtschneiden mit einer im Querschnitt verformten Drahtelektrode
JP2005519954A (ja) * 2002-03-08 2005-07-07 エーザイ株式会社 医薬として有用な大環状化合物
JP2008297317A (ja) * 2002-03-08 2008-12-11 Eisai R & D Management Co Ltd 医薬として有用な大環状化合物
US7799827B2 (en) 2002-03-08 2010-09-21 Eisai Co., Ltd. Macrocyclic compounds useful as pharmaceuticals
US7915306B2 (en) 2002-03-08 2011-03-29 Eisai Co., Ltd. Macrocyclic compounds useful as pharmaceuticals
JP2012193183A (ja) * 2002-03-08 2012-10-11 Eisai R & D Management Co Ltd 医薬として有用な大環状化合物
US8329742B2 (en) 2002-03-08 2012-12-11 Eisai Co., Ltd. Macrocyclic compounds useful as pharmaceuticals
JP2008514635A (ja) * 2004-09-27 2008-05-08 コーザン バイオサイエンシス インコーポレイテッド 特異的キナーゼ阻害剤
US8609640B2 (en) 2007-07-25 2013-12-17 Eisai, Inc. Multikinase inhibitors for use in the treatment of cancer
US8937056B2 (en) 2007-07-25 2015-01-20 Eisai R&D Management Co., Ltd. Multikinase inhibitors for use in the treatment of cancer

Also Published As

Publication number Publication date
NO934372D0 (no) 1993-12-02
CA2110553A1 (en) 1994-06-05
MX9307608A (es) 1995-01-31
AU5211293A (en) 1994-06-16
FI935409L (fi) 1994-06-05
NO934372L (no) 1994-06-06
IL107838A0 (en) 1994-04-12
ZA939088B (en) 1995-06-05
KR940014377A (ko) 1994-07-18
CZ261493A3 (en) 1994-07-13
HU9303444D0 (en) 1994-04-28
GB9225396D0 (en) 1993-01-27
EP0606044A1 (en) 1994-07-13
HUT65910A (en) 1994-07-28
PL301281A1 (en) 1994-06-13
FI935409A0 (fi) 1993-12-02
FI935409A7 (fi) 1994-06-05
TW258736B (enExample) 1995-10-01
NZ250344A (en) 1995-10-26
SK135493A3 (en) 1994-08-10
CN1095417A (zh) 1994-11-23

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