SK134398A3 - Aqueous solution of the pyridoxylated polymerized hemoglobin and method for preparing the same - Google Patents

Aqueous solution of the pyridoxylated polymerized hemoglobin and method for preparing the same Download PDF

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Publication number
SK134398A3
SK134398A3 SK1343-98A SK134398A SK134398A3 SK 134398 A3 SK134398 A3 SK 134398A3 SK 134398 A SK134398 A SK 134398A SK 134398 A3 SK134398 A3 SK 134398A3
Authority
SK
Slovakia
Prior art keywords
solution
hemoglobin
pyridoxylated
polymerized
less
Prior art date
Application number
SK1343-98A
Other languages
English (en)
Slovak (sk)
Inventor
Richard E Dewoskin
Marc D Doubleday
Original Assignee
Northfield Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Northfield Lab filed Critical Northfield Lab
Publication of SK134398A3 publication Critical patent/SK134398A3/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SK1343-98A 1996-03-28 1997-03-27 Aqueous solution of the pyridoxylated polymerized hemoglobin and method for preparing the same SK134398A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1438996P 1996-03-28 1996-03-28
PCT/US1997/005088 WO1997035883A1 (en) 1996-03-28 1997-03-27 Method and apparatus for preparing an acellular red blood cell substitute

Publications (1)

Publication Number Publication Date
SK134398A3 true SK134398A3 (en) 2001-01-18

Family

ID=21765191

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1343-98A SK134398A3 (en) 1996-03-28 1997-03-27 Aqueous solution of the pyridoxylated polymerized hemoglobin and method for preparing the same

Country Status (26)

Country Link
US (5) US6498141B2 (no)
EP (1) EP0928294B1 (no)
JP (1) JP2000507947A (no)
CN (1) CN1129608C (no)
AP (1) AP1028A (no)
AT (1) ATE241646T1 (no)
AU (1) AU740210B2 (no)
BG (1) BG63919B1 (no)
BR (1) BR9708388A (no)
CA (1) CA2250274C (no)
CZ (1) CZ299357B6 (no)
DE (1) DE69722422T2 (no)
DK (1) DK0928294T3 (no)
ES (1) ES2200177T3 (no)
IL (1) IL126376A (no)
IS (1) IS4854A (no)
NO (1) NO324121B1 (no)
NZ (2) NZ332067A (no)
OA (1) OA10884A (no)
PL (1) PL187923B1 (no)
PT (1) PT928294E (no)
RO (1) RO121089B1 (no)
RU (1) RU2203087C2 (no)
SK (1) SK134398A3 (no)
UA (1) UA64710C2 (no)
WO (1) WO1997035883A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000507947A (ja) * 1996-03-28 2000-06-27 ノースフイールド ラボラトリーズ インコーポレイテツド 無細胞性赤血球代用物を製造する方法及び装置
CA2444590C (en) 2001-04-18 2009-12-01 Robert L. Mcginnis Stabilized hemoglobin solutions
DE10220992A1 (de) * 2002-05-11 2003-12-04 Sanguibiotech Ag Verwendung eines oder mehrerer Sauerstoffträger, ausgewählt aus Hämoglobin, Myoglobin und Derivaten hiervon zur Behandlung einer Organfunktionsstörung infolge eines akuten Versorgungsmangels und zur Behandlung/Vermeidung einer Gewebeschädigung infolge einer solchen Störung
EP1553968A4 (en) * 2002-10-03 2009-06-24 Northfield Lab METHOD FOR TREATING PATIENTS WITH MASSIVE BLOOD LOSS
EP1592437A4 (en) * 2003-01-29 2007-12-26 Northfield Lab POLYMERIZED HEMOGLOBIN SOLUTIONS WITH REDUCED TETRAMER QUANTITY AND MANUFACTURING METHOD
SE0501462L (sv) * 2005-06-23 2006-09-26 Proliff Ab Förfarande för framställning av blodplättslysat
US20090004159A1 (en) * 2006-01-24 2009-01-01 The Board Of Trustees Of The University Of Illinoi Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
US20070196810A1 (en) * 2006-01-24 2007-08-23 Northfield Laboratories Inc. Polymerized Hemoglobin Media and its Use in Isolation and Transplantation of Islet Cells
RU2340354C1 (ru) * 2007-06-05 2008-12-10 Общество с ограниченной ответственностью "Геленпол" Кровезаменитель с функцией переноса кислорода
RU2361608C1 (ru) 2008-03-18 2009-07-20 Общество С Ограниченной Ответственностью "Научно-Производственная Компания "Медбиофарм" Кровезаменитель с функцией переноса кислорода, фармацевтическая композиция (варианты)
AU2018304174A1 (en) 2017-07-18 2020-02-06 VirTech Bio, Inc. Blood substitutes comprising hemoglobin and methods of making

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826811A (en) * 1986-06-20 1989-05-02 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5194590A (en) * 1986-06-20 1993-03-16 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5464814A (en) * 1986-06-20 1995-11-07 Northfield Laboratories, Inc. Acellular red blood cell substitute
IL87708A (en) * 1988-09-08 1994-04-12 Technion Inst For Research And Hemoglobin-based blood substitute possessing a colloid oncotic pressure substantially similar to human blood and method for the preparation thereof
SE9001378D0 (sv) * 1990-04-18 1990-04-18 Kabivitrum Ab A method for the preparation of pyridoxylated hemoglobin
TW381022B (en) * 1993-08-16 2000-02-01 Hsia Jen Chang Compositions and methods utilizing nitroxides to avoid oxygen toxicity, particularly in stabilized, polymerized, conjugated, or encapsulated hemoglobin used as a red cell substitute
JP2000507947A (ja) * 1996-03-28 2000-06-27 ノースフイールド ラボラトリーズ インコーポレイテツド 無細胞性赤血球代用物を製造する方法及び装置
US5998361A (en) * 1996-10-18 1999-12-07 University Of Maryland At Baltimore Polymerized hemoglobin

Also Published As

Publication number Publication date
IS4854A (is) 1998-09-28
DK0928294T3 (da) 2003-09-22
OA10884A (en) 2001-10-11
PT928294E (pt) 2003-10-31
BG63919B1 (bg) 2003-06-30
AP1028A (en) 2001-11-30
CN1219939A (zh) 1999-06-16
IL126376A0 (en) 1999-05-09
CA2250274C (en) 2003-09-16
US20100197566A1 (en) 2010-08-05
NO324121B1 (no) 2007-08-27
DE69722422T2 (de) 2004-05-06
ES2200177T3 (es) 2004-03-01
US20030191050A1 (en) 2003-10-09
EP0928294B1 (en) 2003-05-28
AU740210B2 (en) 2001-11-01
PL329108A1 (en) 1999-03-15
WO1997035883A1 (en) 1997-10-02
JP2000507947A (ja) 2000-06-27
US6498141B2 (en) 2002-12-24
AU2425397A (en) 1997-10-17
RO121089B1 (ro) 2006-12-29
CZ310098A3 (cs) 1999-09-15
US20050065067A1 (en) 2005-03-24
CN1129608C (zh) 2003-12-03
DE69722422D1 (de) 2003-07-03
IL126376A (en) 2009-09-22
NO984473L (no) 1998-11-25
US20020025343A1 (en) 2002-02-28
US7521417B2 (en) 2009-04-21
NZ332067A (en) 2001-03-30
NO984473D0 (no) 1998-09-25
CA2250274A1 (en) 1997-10-02
US20080108555A1 (en) 2008-05-08
AP9801353A0 (en) 1998-09-30
ATE241646T1 (de) 2003-06-15
EP0928294A1 (en) 1999-07-14
NZ538045A (en) 2006-11-30
PL187923B1 (pl) 2004-11-30
UA64710C2 (en) 2004-03-15
BR9708388A (pt) 2000-01-04
CZ299357B6 (cs) 2008-07-02
BG102810A (en) 1999-09-30
RU2203087C2 (ru) 2003-04-27

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