SK12222003A3 - Beta-karbolínové deriváty, spôsob ich prípravy, farmaceutická kompozícia s ich obsahom a ich použitia proti depresii a úzkosti - Google Patents
Beta-karbolínové deriváty, spôsob ich prípravy, farmaceutická kompozícia s ich obsahom a ich použitia proti depresii a úzkosti Download PDFInfo
- Publication number
- SK12222003A3 SK12222003A3 SK1222-2003A SK12222003A SK12222003A3 SK 12222003 A3 SK12222003 A3 SK 12222003A3 SK 12222003 A SK12222003 A SK 12222003A SK 12222003 A3 SK12222003 A3 SK 12222003A3
- Authority
- SK
- Slovakia
- Prior art keywords
- compound
- free base
- addition salt
- acid addition
- anxiety
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0108337.7A GB0108337D0 (en) | 2001-04-03 | 2001-04-03 | Organic compounds |
| PCT/EP2002/003624 WO2002081471A1 (fr) | 2001-04-03 | 2002-04-02 | Derives de beta-carboline et leur utilisation pharmaceutique contre la depression et l'anxiete |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK12222003A3 true SK12222003A3 (sk) | 2004-06-08 |
Family
ID=9912165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1222-2003A SK12222003A3 (sk) | 2001-04-03 | 2002-04-02 | Beta-karbolínové deriváty, spôsob ich prípravy, farmaceutická kompozícia s ich obsahom a ich použitia proti depresii a úzkosti |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6861430B2 (fr) |
| EP (1) | EP1377578B1 (fr) |
| JP (1) | JP4405732B2 (fr) |
| KR (1) | KR100564840B1 (fr) |
| CN (1) | CN1309721C (fr) |
| AR (1) | AR035451A1 (fr) |
| AT (1) | ATE517104T1 (fr) |
| AU (1) | AU2002316828B2 (fr) |
| BR (1) | BR0208566B1 (fr) |
| CA (1) | CA2440014C (fr) |
| CZ (1) | CZ295992B6 (fr) |
| EC (1) | ECSP034754A (fr) |
| ES (1) | ES2368389T3 (fr) |
| GB (1) | GB0108337D0 (fr) |
| HU (1) | HUP0400317A3 (fr) |
| IL (1) | IL157545A0 (fr) |
| MX (1) | MXPA03009057A (fr) |
| MY (1) | MY134026A (fr) |
| NO (1) | NO20034413L (fr) |
| NZ (1) | NZ528370A (fr) |
| PE (1) | PE20021018A1 (fr) |
| PL (1) | PL210861B1 (fr) |
| PT (1) | PT1377578E (fr) |
| RU (1) | RU2003130644A (fr) |
| SK (1) | SK12222003A3 (fr) |
| WO (1) | WO2002081471A1 (fr) |
| ZA (1) | ZA200306108B (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
| US7872133B2 (en) | 2003-06-23 | 2011-01-18 | Ono Pharmaceutical Co., Ltd. | Tricyclic heterocycle compound |
| AR051780A1 (es) * | 2004-11-29 | 2007-02-07 | Japan Tobacco Inc | Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos |
| PT1829874E (pt) | 2004-12-22 | 2014-04-10 | Ono Pharmaceutical Co | Composto tricíclico e sua utilização |
| US7879859B2 (en) * | 2005-11-21 | 2011-02-01 | Merck Sharp & Dohme Corp. | Diagnosis and treatment of type 2 diabetes and other disorders |
| WO2007062175A2 (fr) * | 2005-11-21 | 2007-05-31 | Amgen Inc. | Antagonistes cxcr3 |
| EP2178537A4 (fr) * | 2007-07-19 | 2011-08-17 | Merck Sharp & Dohme | Dérivés de bêta-carboline en tant que composés antidiabétiques |
| WO2009016329A1 (fr) * | 2007-07-31 | 2009-02-05 | Cambridge Enterprise Limited | Utilisation d'antagonistes du récepteur gabaa pour traiter un trouble cognitif dans des patients avec des états psychiatriques |
| WO2009155388A1 (fr) | 2008-06-20 | 2009-12-23 | Bristol-Myers Squibb Company | Composés d'imidazopyridine et d'imidazopyrazine utilisés comme inhibiteurs de kinase |
| ES2541528T3 (es) | 2008-11-19 | 2015-07-21 | Forum Pharmaceuticals Inc. | Tratamiento de trastornos cognitivos con (R)-7-cloro-N-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida y sales farmacéuticamente aceptables de la misma |
| TW201028414A (en) | 2009-01-16 | 2010-08-01 | Merck Sharp & Dohme | Oxadiazole beta carboline derivatives as antidiabetic compounds |
| CA2785790A1 (fr) | 2010-01-15 | 2011-07-21 | Merck Sharp & Dohme Corp. | Derives oxadiazole beta-carboline comme composes antidiabetiques |
| CN103221411B (zh) | 2010-05-17 | 2016-05-11 | 富瑞姆制药公司 | (R)-7-氯-N-(奎宁环-3-基)苯并[b]噻吩-2-甲酰胺盐酸盐单水合物的晶型 |
| AU2013259871A1 (en) | 2012-05-08 | 2014-11-20 | Forum Pharmaceuticals Inc. | Methods of maintaining, treating or improving cognitive function |
| CN111349096B (zh) * | 2020-04-14 | 2021-03-09 | 石河子大学 | 一种吲哚类化合物及其制备方法、应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4118741A1 (de) * | 1991-06-05 | 1992-12-10 | Schering Ag | Neue hetaryloxy-(beta)-carboline, deren herstellung und verwendung in arzneimitteln |
| US6057340A (en) * | 1998-02-03 | 2000-05-02 | American Home Products Corporation | Oxazole derivatives as serotonin-1A receptor agonists |
| NZ508765A (en) | 1998-06-12 | 2003-10-31 | Sod Conseils Rech Applic | Beta-carboline derivatives and pharmaceuticals thereof that selectively bind somatostatin receptor subtypes |
-
2001
- 2001-04-03 GB GBGB0108337.7A patent/GB0108337D0/en not_active Ceased
-
2002
- 2002-03-27 AR ARP020101141A patent/AR035451A1/es not_active Application Discontinuation
- 2002-04-02 SK SK1222-2003A patent/SK12222003A3/sk not_active Application Discontinuation
- 2002-04-02 NZ NZ528370A patent/NZ528370A/en not_active IP Right Cessation
- 2002-04-02 AU AU2002316828A patent/AU2002316828B2/en not_active Ceased
- 2002-04-02 RU RU2003130644/04A patent/RU2003130644A/ru not_active Application Discontinuation
- 2002-04-02 WO PCT/EP2002/003624 patent/WO2002081471A1/fr active IP Right Grant
- 2002-04-02 US US10/472,630 patent/US6861430B2/en not_active Expired - Fee Related
- 2002-04-02 IL IL15754502A patent/IL157545A0/xx unknown
- 2002-04-02 CA CA2440014A patent/CA2440014C/fr not_active Expired - Fee Related
- 2002-04-02 CZ CZ20032655A patent/CZ295992B6/cs not_active IP Right Cessation
- 2002-04-02 CN CNB028077814A patent/CN1309721C/zh not_active Expired - Fee Related
- 2002-04-02 PT PT02745204T patent/PT1377578E/pt unknown
- 2002-04-02 HU HU0400317A patent/HUP0400317A3/hu unknown
- 2002-04-02 EP EP02745204A patent/EP1377578B1/fr not_active Expired - Lifetime
- 2002-04-02 KR KR1020037012933A patent/KR100564840B1/ko not_active IP Right Cessation
- 2002-04-02 AT AT02745204T patent/ATE517104T1/de active
- 2002-04-02 JP JP2002579459A patent/JP4405732B2/ja not_active Expired - Fee Related
- 2002-04-02 PL PL362571A patent/PL210861B1/pl not_active IP Right Cessation
- 2002-04-02 ES ES02745204T patent/ES2368389T3/es not_active Expired - Lifetime
- 2002-04-02 PE PE2002000264A patent/PE20021018A1/es not_active Application Discontinuation
- 2002-04-02 MY MYPI20021189A patent/MY134026A/en unknown
- 2002-04-02 BR BRPI0208566-6B1A patent/BR0208566B1/pt not_active IP Right Cessation
- 2002-04-02 MX MXPA03009057A patent/MXPA03009057A/es active IP Right Grant
-
2003
- 2003-08-07 ZA ZA200306108A patent/ZA200306108B/en unknown
- 2003-08-27 EC EC2003004754A patent/ECSP034754A/es unknown
- 2003-10-02 NO NO20034413A patent/NO20034413L/no not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5972964B2 (ja) | 抗腫瘍剤としての三環式および四環式ピラゾロ［３，４−ｂ］ピリジン化合物 | |
| JP5524071B2 (ja) | 複素環フェニルアミドｔ型カルシウムチャネルアンタゴニスト | |
| US9045428B2 (en) | Substituted heterocyclic compounds | |
| JP2011500808A (ja) | 複素環アミドｔ型カルシウムチャネルアンタゴニスト | |
| SK12222003A3 (sk) | Beta-karbolínové deriváty, spôsob ich prípravy, farmaceutická kompozícia s ich obsahom a ich použitia proti depresii a úzkosti | |
| AU2007311983B2 (en) | An Alzheimer' s disease progression inhibitor containing heterocyclic compound | |
| JPH11501925A (ja) | 置換Ｎ−アリールメチルおよびヘテロシクリルメチル−１Ｈ−ピラゾロ〔３，４−ｂ〕キノリン−４−アミン並びにそれらを含有する組成物 | |
| AU2011288876A1 (en) | Phthalazinone ketone derivative, preparation method thereof, and pharmaceutical use thereof | |
| JP2008537741A (ja) | Ｐ２ｘ７調節因子としてのビシクロヘテロアリール化合物およびそれらの使用 | |
| WO2017162007A1 (fr) | Dérivé d'amide aromatique et procédé de préparation et application médicale correspondants | |
| EP2354139A1 (fr) | Pyrrolopyridines en tant qu'inhibiteurs de kinase | |
| JP2016520118A (ja) | Ｂｅｔ阻害剤としてのピラゾロ−ピロリジン−４−オン誘導体および疾患の処置におけるその使用 | |
| JP2011500807A (ja) | ピラジニルアミドｔ型カルシウムチャネルアンタゴニスト | |
| HU205354B (en) | Process for producing new tricyclic benzimidazoles and pharmaceutical compositions comprising same | |
| JP2008519818A (ja) | Ｃｎｓ障害の治療のためのアザベンゾオキサゾール | |
| US20090181986A1 (en) | Substituted heterocyclic compounds | |
| AU2002316828A1 (en) | Beta-carboline derivatives and its pharmaceutical use against depression and anxiety | |
| JP4285994B2 (ja) | 複素環化合物及びそれを有効成分とする脳機能改善剤 | |
| KR100820006B1 (ko) | 헤테로사이클릭 ｇａｂａ-ａ 아형 선택적 수용체 조절제 | |
| JP5898815B2 (ja) | 新規なピラゾロピリミジン | |
| TW200924772A (en) | Heterobicyclic-substituted quinolones useful as nitric oxide synthase inhibitors | |
| WO2022028556A1 (fr) | Inhibiteur de cdk9 et son utilisation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC9A | Refused patent application |