SI9300663B - Nove selektivne spojine, ki inhibirajo aromatazo - Google Patents
Nove selektivne spojine, ki inhibirajo aromatazo Download PDFInfo
- Publication number
- SI9300663B SI9300663B SI9300663A SI9300663A SI9300663B SI 9300663 B SI9300663 B SI 9300663B SI 9300663 A SI9300663 A SI 9300663A SI 9300663 A SI9300663 A SI 9300663A SI 9300663 B SI9300663 B SI 9300663B
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- SI
- Slovenia
- Prior art keywords
- choh
- compound according
- pharmaceutically acceptable
- sign
- acid addition
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 16
- 102000014654 Aromatase Human genes 0.000 title claims abstract 3
- 108010078554 Aromatase Proteins 0.000 title claims abstract 3
- 230000002401 inhibitory effect Effects 0.000 title abstract 3
- 239000002253 acid Substances 0.000 claims abstract 8
- 231100000252 nontoxic Toxicity 0.000 claims abstract 8
- 230000003000 nontoxic effect Effects 0.000 claims abstract 8
- 150000003839 salts Chemical class 0.000 claims abstract 8
- IYABWNGZIDDRAK-UHFFFAOYSA-N allene Chemical group C=C=C IYABWNGZIDDRAK-UHFFFAOYSA-N 0.000 claims abstract 2
- 229910052736 halogen Inorganic materials 0.000 claims abstract 2
- 150000002367 halogens Chemical class 0.000 claims abstract 2
- 125000001425 triazolyl group Chemical group 0.000 claims abstract 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 3
- 239000005977 Ethylene Substances 0.000 claims 3
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 claims 3
- UAPNUNDZDVNTDQ-UHFFFAOYSA-N 4,5-diphenyl-1,2,3-triazole Chemical class C1=CC=CC=C1C1=NNN=C1C1=CC=CC=C1 UAPNUNDZDVNTDQ-UHFFFAOYSA-N 0.000 claims 1
- GSNCTVZHKAPYCM-UHFFFAOYSA-N 4-[3-(4-fluorophenyl)-1-(1,2,4-triazol-1-yl)prop-1-enyl]benzonitrile Chemical compound C1=CC(F)=CC=C1CC=C(N1N=CN=C1)C1=CC=C(C#N)C=C1 GSNCTVZHKAPYCM-UHFFFAOYSA-N 0.000 claims 1
- SLJZVZKQYSKYNV-UHFFFAOYSA-N 4-[3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile Chemical compound C=1C=C(C#N)C=CC=1C(N1N=CN=C1)C(O)CC1=CC=C(F)C=C1 SLJZVZKQYSKYNV-UHFFFAOYSA-N 0.000 claims 1
- MMRJZAQWNKAGLS-UHFFFAOYSA-N 4-[3-(4-fluorophenyl)-3-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile Chemical compound C=1C=C(F)C=CC=1C(O)CC(N1N=CN=C1)C1=CC=C(C#N)C=C1 MMRJZAQWNKAGLS-UHFFFAOYSA-N 0.000 claims 1
- YYVLEXMHDNXBHZ-UHFFFAOYSA-N 4-[4-(4-fluorophenyl)-1-(1,2,4-triazol-1-yl)but-1-enyl]benzonitrile Chemical compound C1=CC(F)=CC=C1CCC=C(N1N=CN=C1)C1=CC=C(C#N)C=C1 YYVLEXMHDNXBHZ-UHFFFAOYSA-N 0.000 claims 1
- XGZOVOHKZLWBOH-UHFFFAOYSA-N 4-[4-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)butyl]benzonitrile Chemical compound C=1C=C(C#N)C=CC=1C(N1N=CN=C1)C(O)CCC1=CC=C(F)C=C1 XGZOVOHKZLWBOH-UHFFFAOYSA-N 0.000 claims 1
- UCARAIZDOHWRTD-UHFFFAOYSA-N 4-[4-(4-fluorophenyl)-2-oxo-1-(1,2,4-triazol-1-yl)butyl]benzonitrile Chemical compound C1=CC(F)=CC=C1CCC(=O)C(N1N=CN=C1)C1=CC=C(C#N)C=C1 UCARAIZDOHWRTD-UHFFFAOYSA-N 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 2
- 208000004403 Prostatic Hyperplasia Diseases 0.000 abstract 2
- -1 heterocyclyl radical Chemical class 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- JNCMHMUGTWEVOZ-UHFFFAOYSA-N F[CH]F Chemical compound F[CH]F JNCMHMUGTWEVOZ-UHFFFAOYSA-N 0.000 abstract 1
- 108010081348 HRT1 protein Hairy Proteins 0.000 abstract 1
- 102100021881 Hairy/enhancer-of-split related with YRPW motif protein 1 Human genes 0.000 abstract 1
- 102000004317 Lyases Human genes 0.000 abstract 1
- 108090000856 Lyases Proteins 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940011871 estrogen Drugs 0.000 abstract 1
- 239000000262 estrogen Substances 0.000 abstract 1
- VUWZPRWSIVNGKG-UHFFFAOYSA-N fluoromethane Chemical compound F[CH2] VUWZPRWSIVNGKG-UHFFFAOYSA-N 0.000 abstract 1
- 125000001786 isothiazolyl group Chemical group 0.000 abstract 1
- 125000000842 isoxazolyl group Chemical group 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002971 oxazolyl group Chemical group 0.000 abstract 1
- 125000003226 pyrazolyl group Chemical group 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
- 125000000335 thiazolyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/61—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Pyridine Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9226209A GB2273704B (en) | 1992-12-16 | 1992-12-16 | Triazolyl diaryl selective aromatase inhibiting compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SI9300663A SI9300663A (en) | 1994-09-30 |
| SI9300663B true SI9300663B (sl) | 2002-02-28 |
Family
ID=10726697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9300663A SI9300663B (sl) | 1992-12-16 | 1993-12-16 | Nove selektivne spojine, ki inhibirajo aromatazo |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US5703109A (cs) |
| EP (1) | EP0674626B1 (cs) |
| JP (1) | JP3186771B2 (cs) |
| KR (1) | KR100347639B1 (cs) |
| CN (1) | CN1056835C (cs) |
| AT (1) | ATE194833T1 (cs) |
| AU (1) | AU682332B2 (cs) |
| BG (1) | BG62930B1 (cs) |
| CA (1) | CA2150904A1 (cs) |
| CZ (1) | CZ283043B6 (cs) |
| DE (1) | DE69329072T2 (cs) |
| DK (1) | DK0674626T3 (cs) |
| EE (1) | EE03155B1 (cs) |
| ES (1) | ES2148312T3 (cs) |
| FI (1) | FI952867A7 (cs) |
| GB (1) | GB2273704B (cs) |
| GR (1) | GR3034618T3 (cs) |
| HR (1) | HRP931494B1 (cs) |
| IL (1) | IL107714A (cs) |
| LT (1) | LT3151B (cs) |
| NO (1) | NO310237B1 (cs) |
| NZ (1) | NZ258588A (cs) |
| PL (1) | PL176413B1 (cs) |
| PT (1) | PT674626E (cs) |
| RO (1) | RO113986B1 (cs) |
| RU (1) | RU2131418C1 (cs) |
| SI (1) | SI9300663B (cs) |
| SK (1) | SK281667B6 (cs) |
| TW (1) | TW327169B (cs) |
| WO (1) | WO1994013645A1 (cs) |
| ZA (1) | ZA938717B (cs) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6063930A (en) * | 1996-04-03 | 2000-05-16 | Merck & Co., Inc. | Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors |
| US6080870A (en) * | 1996-04-03 | 2000-06-27 | Merck & Co., Inc. | Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors |
| AU715658B2 (en) * | 1996-04-03 | 2000-02-10 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| US5972921A (en) * | 1997-12-12 | 1999-10-26 | Hormos Medical Oy Ltd. | Use of an aromatase inhibitor in the treatment of decreased androgen to estrogen ratio and detrusor urethral sphincter dyssynergia in men |
| WO2002009703A1 (en) * | 2000-07-10 | 2002-02-07 | Hormos Medical Corporation | Method for treating cryptorchidism |
| EP2762140B1 (en) * | 2001-02-19 | 2017-03-22 | Novartis AG | Treatment of solid brain tumours with a rapamycin derivative |
| FI20010905A0 (fi) * | 2001-05-02 | 2001-05-02 | Vetcare Oy | Uusi eläinlääke |
| WO2003050093A1 (en) * | 2001-12-11 | 2003-06-19 | Emory University | Bis(cyanophenyl)methyl-triazole for use in prevention of breast cancer |
| RU2222326C1 (ru) * | 2002-10-09 | 2004-01-27 | Российский онкологический научный центр им. Н.Н.Блохина РАМН | Способ лечения саркомы юинга |
| JP2004196795A (ja) * | 2002-12-16 | 2004-07-15 | Wyeth | 外部寄生虫駆除剤としてのｎ−フェニル−３−シクロプロピルピラゾール−４−カルボニトリル |
| EP1431292A1 (en) * | 2002-12-16 | 2004-06-23 | Laboratoire Theramex | 1-N-phenylamino-1H-imidazole derivatives as aromatase inhibitors |
| US7345073B2 (en) | 2003-02-07 | 2008-03-18 | Hormos Medical Ltd. | Method for treating cryptorchidism |
| US20040248989A1 (en) | 2003-06-05 | 2004-12-09 | Risto Santti | Method for the treatment or prevention of lower urinary tract symptoms |
| JP4834557B2 (ja) * | 2003-12-15 | 2011-12-14 | ラボラトワール テラメックス | １−ｎ−フェニルアミノ−１ｈ−イミダゾール誘導体及びこれを含む医薬組成物 |
| CA2652783C (en) * | 2006-05-22 | 2015-07-14 | Hormos Medical Ltd. | Selective estrogen receptor modulators or aromatase inhibitors for treating chronic nonbacterial prostatitis |
| GB0914767D0 (en) * | 2009-08-24 | 2009-09-30 | Sterix Ltd | Compound |
| CN102884072A (zh) | 2010-04-08 | 2013-01-16 | 爱默蕾大学 | 被取代的雄甾-4-烯二酮 |
| AR083626A1 (es) * | 2010-05-27 | 2013-03-13 | Bayer Cropscience Ag | Derivados de alcanoles heterociclicos |
| KR101583521B1 (ko) | 2015-07-31 | 2016-01-08 | (주) 엘림비엠에스 | 내오염, 내마모 성능과 시공 작업성 및 광도 성능이 개선된 피브이씨 타일 바닥의 코팅방법 |
| US10905253B2 (en) | 2018-04-19 | 2021-02-02 | Wonderland Switzerland Ag | Child carrier |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1580535A (en) | 1976-08-27 | 1980-12-03 | Ici Ltd | Substituted ketones and their use as herbicides |
| US4978672A (en) | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
| US4749713A (en) * | 1986-03-07 | 1988-06-07 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US4937250A (en) | 1988-03-07 | 1990-06-26 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US5071861A (en) | 1986-03-07 | 1991-12-10 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US5112845A (en) * | 1986-03-07 | 1992-05-12 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| JPH032168A (ja) | 1989-03-30 | 1991-01-08 | Farmos Yhtymae Oy | アロマターゼ阻害活性を有する新規な４（５）―イミダゾール |
| ES2084687T3 (es) | 1989-07-14 | 1996-05-16 | Ciba Geigy Ag | Benzonitrilos substituidos. |
| US5077374A (en) * | 1990-04-20 | 1991-12-31 | Phillips Petroleum Company | Aromatic sulfide polymers and method of preparation |
| DE4039559A1 (de) * | 1990-12-07 | 1992-06-11 | Schering Ag | Funktionalisierte vinylazole, verfahren zu deren herstellung, pharmazeutische praeparate die diese vinylazole enthalten sowie deren verwendung zur herstellung von arzneimitteln |
| GB9125924D0 (en) * | 1991-06-18 | 1992-02-05 | Orion Yhtymae Oy | Stereoisomers of an imidazole derivative |
-
1992
- 1992-12-16 GB GB9226209A patent/GB2273704B/en not_active Expired - Fee Related
-
1993
- 1993-11-22 ZA ZA938717A patent/ZA938717B/xx unknown
- 1993-11-23 IL IL10771493A patent/IL107714A/xx not_active IP Right Cessation
- 1993-12-03 LT LTIP1524A patent/LT3151B/lt not_active IP Right Cessation
- 1993-12-14 PT PT94901975T patent/PT674626E/pt unknown
- 1993-12-14 KR KR1019950702444A patent/KR100347639B1/ko not_active Expired - Fee Related
- 1993-12-14 DK DK94901975T patent/DK0674626T3/da active
- 1993-12-14 WO PCT/FI1993/000539 patent/WO1994013645A1/en active IP Right Grant
- 1993-12-14 JP JP51384094A patent/JP3186771B2/ja not_active Expired - Fee Related
- 1993-12-14 CA CA002150904A patent/CA2150904A1/en not_active Abandoned
- 1993-12-14 US US08/436,389 patent/US5703109A/en not_active Expired - Fee Related
- 1993-12-14 SK SK778-95A patent/SK281667B6/sk unknown
- 1993-12-14 RO RO95-01149A patent/RO113986B1/ro unknown
- 1993-12-14 AT AT94901975T patent/ATE194833T1/de not_active IP Right Cessation
- 1993-12-14 RU RU95114360/04A patent/RU2131418C1/ru not_active IP Right Cessation
- 1993-12-14 AU AU56523/94A patent/AU682332B2/en not_active Ceased
- 1993-12-14 TW TW082110583A patent/TW327169B/zh active
- 1993-12-14 DE DE69329072T patent/DE69329072T2/de not_active Expired - Fee Related
- 1993-12-14 FI FI952867A patent/FI952867A7/fi unknown
- 1993-12-14 PL PL93309350A patent/PL176413B1/pl unknown
- 1993-12-14 ES ES94901975T patent/ES2148312T3/es not_active Expired - Lifetime
- 1993-12-14 NZ NZ258588A patent/NZ258588A/en unknown
- 1993-12-14 CZ CZ951532A patent/CZ283043B6/cs not_active IP Right Cessation
- 1993-12-14 EP EP94901975A patent/EP0674626B1/en not_active Expired - Lifetime
- 1993-12-15 HR HR931494A patent/HRP931494B1/xx not_active IP Right Cessation
- 1993-12-15 CN CN93120844A patent/CN1056835C/zh not_active Expired - Fee Related
- 1993-12-16 SI SI9300663A patent/SI9300663B/sl unknown
-
1994
- 1994-11-22 EE EE9400434A patent/EE03155B1/xx not_active IP Right Cessation
-
1995
- 1995-06-05 BG BG99699A patent/BG62930B1/bg unknown
- 1995-06-15 NO NO19952365A patent/NO310237B1/no unknown
-
1997
- 1997-09-15 US US08/929,424 patent/US5962495A/en not_active Expired - Fee Related
-
2000
- 2000-10-13 GR GR20000402303T patent/GR3034618T3/el not_active IP Right Cessation
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