SI2854841T1 - Glikozilacijske izooblike humanega tkivnega kalikreina-1 - Google Patents

Glikozilacijske izooblike humanega tkivnega kalikreina-1

Info

Publication number
SI2854841T1
SI2854841T1 SI201330639A SI201330639A SI2854841T1 SI 2854841 T1 SI2854841 T1 SI 2854841T1 SI 201330639 A SI201330639 A SI 201330639A SI 201330639 A SI201330639 A SI 201330639A SI 2854841 T1 SI2854841 T1 SI 2854841T1
Authority
SI
Slovenia
Prior art keywords
human tissue
tissue kallikrein
glycosylation isoforms
isoforms
glycosylation
Prior art date
Application number
SI201330639A
Other languages
English (en)
Inventor
Matthew Charles
Tadeusz Kolodka
Mark Williams
Original Assignee
Diamedica Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diamedica Inc. filed Critical Diamedica Inc.
Publication of SI2854841T1 publication Critical patent/SI2854841T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4853—Kallikrein (3.4.21.34 or 3.4.21.35)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21035—Tissue kallikrein (3.4.21.35)
SI201330639A 2012-06-04 2013-06-04 Glikozilacijske izooblike humanega tkivnega kalikreina-1 SI2854841T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261655388P 2012-06-04 2012-06-04
US201361789978P 2013-03-15 2013-03-15
PCT/CA2013/050425 WO2013181755A1 (en) 2012-06-04 2013-06-04 Human tissue kallikrein 1 glycosylation isoforms

Publications (1)

Publication Number Publication Date
SI2854841T1 true SI2854841T1 (sl) 2017-06-30

Family

ID=49670526

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201330639A SI2854841T1 (sl) 2012-06-04 2013-06-04 Glikozilacijske izooblike humanega tkivnega kalikreina-1

Country Status (13)

Country Link
US (3) US20130323222A1 (sl)
EP (1) EP2854841B1 (sl)
CA (1) CA2880085C (sl)
CY (1) CY1119073T1 (sl)
DK (1) DK2854841T3 (sl)
ES (1) ES2625548T3 (sl)
HR (1) HRP20170673T1 (sl)
HU (1) HUE032613T2 (sl)
LT (1) LT2854841T (sl)
PL (1) PL2854841T3 (sl)
PT (1) PT2854841T (sl)
SI (1) SI2854841T1 (sl)
WO (1) WO2013181755A1 (sl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130315891A1 (en) 2012-05-25 2013-11-28 Matthew Charles Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
DK2854841T3 (en) 2012-06-04 2017-05-22 Diamedica Inc Kallikrein-1-glycosylation isoforms of human tissue
CN110446501A (zh) * 2017-03-09 2019-11-12 代阿麦迪卡股份有限公司 组织激肽释放酶1的剂型
CN116135973A (zh) * 2021-11-16 2023-05-19 江苏众红生物工程创药研究院有限公司 低糖基化修饰的激肽原酶及其聚乙二醇修饰物和应用

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PT2854841T (pt) 2017-05-15
US20170119862A1 (en) 2017-05-04
CA2880085C (en) 2021-09-07
WO2013181755A1 (en) 2013-12-12
US20130323222A1 (en) 2013-12-05
PL2854841T3 (pl) 2017-08-31
CA2880085A1 (en) 2013-12-12
ES2625548T3 (es) 2017-07-19
US9364521B2 (en) 2016-06-14
EP2854841A4 (en) 2016-03-09
EP2854841B1 (en) 2017-02-22
HRP20170673T1 (hr) 2017-07-14
CY1119073T1 (el) 2018-01-10
US20150196624A1 (en) 2015-07-16
HUE032613T2 (en) 2017-10-30
LT2854841T (lt) 2017-06-12

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