SI1497019T1 - Pirolo-triazin anilin spojine uporabne kot inhibitorji kinaze - Google Patents

Pirolo-triazin anilin spojine uporabne kot inhibitorji kinaze

Info

Publication number
SI1497019T1
SI1497019T1 SI200332435T SI200332435T SI1497019T1 SI 1497019 T1 SI1497019 T1 SI 1497019T1 SI 200332435 T SI200332435 T SI 200332435T SI 200332435 T SI200332435 T SI 200332435T SI 1497019 T1 SI1497019 T1 SI 1497019T1
Authority
SI
Slovenia
Prior art keywords
pyrrolo
kinase inhibitors
compounds useful
aniline compounds
triazine
Prior art date
Application number
SI200332435T
Other languages
English (en)
Inventor
Alaric Dyckman
John Hynes
Katerina Leftheris
Chunjian Liu
Stephen T. Wrobleski
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of SI1497019T1 publication Critical patent/SI1497019T1/sl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
    • C07D253/10—Condensed 1,2,4-triazines; Hydrogenated condensed 1,2,4-triazines

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SI200332435T 2002-04-23 2003-04-15 Pirolo-triazin anilin spojine uporabne kot inhibitorji kinaze SI1497019T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37493802P 2002-04-23 2002-04-23
EP20030724157 EP1497019B1 (en) 2002-04-23 2003-04-15 Pyrrolo-triazine aniline compounds useful as kinase inhibitors
PCT/US2003/012426 WO2003090912A1 (en) 2002-04-23 2003-04-15 Pyrrolo-triazine aniline compounds useful as kinase inhibitors

Publications (1)

Publication Number Publication Date
SI1497019T1 true SI1497019T1 (sl) 2015-08-31

Family

ID=29270573

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200332435T SI1497019T1 (sl) 2002-04-23 2003-04-15 Pirolo-triazin anilin spojine uporabne kot inhibitorji kinaze

Country Status (30)

Country Link
US (5) US7160883B2 (sl)
EP (2) EP2289894A3 (sl)
JP (2) JP4669225B2 (sl)
KR (1) KR101025675B1 (sl)
CN (2) CN102093363B (sl)
AR (1) AR039649A1 (sl)
AU (1) AU2003231034B2 (sl)
BR (1) BR0309669A (sl)
CA (1) CA2483164C (sl)
DK (1) DK1497019T3 (sl)
ES (1) ES2543711T3 (sl)
GE (1) GEP20074148B (sl)
HR (1) HRP20040988A2 (sl)
HU (1) HUE025353T2 (sl)
IL (2) IL164573A (sl)
IS (1) IS7505A (sl)
MX (1) MXPA04010379A (sl)
MY (1) MY132094A (sl)
NO (1) NO329503B1 (sl)
NZ (1) NZ536014A (sl)
PE (1) PE20040590A1 (sl)
PL (1) PL219736B1 (sl)
PT (1) PT1497019E (sl)
RS (1) RS92004A (sl)
RU (1) RU2375363C2 (sl)
SI (1) SI1497019T1 (sl)
TW (1) TWI312782B (sl)
UA (1) UA78562C2 (sl)
WO (1) WO2003090912A1 (sl)
ZA (1) ZA200408541B (sl)

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US6670357B2 (en) * 2000-11-17 2003-12-30 Bristol-Myers Squibb Company Methods of treating p38 kinase-associated conditions and pyrrolotriazine compounds useful as kinase inhibitors
PL219736B1 (pl) * 2002-04-23 2015-07-31 Bristol Myers Squibb Co Pochodna pirolotriazynoaniliny, kompozycja farmaceutyczna i jej zastosowanie
TW200400034A (en) 2002-05-20 2004-01-01 Bristol Myers Squibb Co Pyrazolo-pyrimidine aniline compounds useful as kinase inhibitors
TW200401638A (en) * 2002-06-20 2004-02-01 Bristol Myers Squibb Co Heterocyclic inhibitors of kinases
TWI329112B (en) * 2002-07-19 2010-08-21 Bristol Myers Squibb Co Novel inhibitors of kinases
WO2004013145A1 (en) * 2002-08-02 2004-02-12 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
TW200420565A (en) * 2002-12-13 2004-10-16 Bristol Myers Squibb Co C-6 modified indazolylpyrrolotriazines
JP2006516653A (ja) 2003-02-05 2006-07-06 ブリストル−マイヤーズ　スクイブ　カンパニー キナーゼ阻害剤ピロロトリアジンの製造方法
JP2007506741A (ja) * 2003-09-23 2007-03-22 メルク　エンド　カムパニー　インコーポレーテッド 向代謝性グルタミン酸受容体のピラゾール系調節剤
US7419978B2 (en) * 2003-10-22 2008-09-02 Bristol-Myers Squibb Company Phenyl-aniline substituted bicyclic compounds useful as kinase inhibitors
US7309708B2 (en) * 2003-11-20 2007-12-18 Birstol-Myers Squibb Company Hepatitis C virus inhibitors
EP1692110A1 (en) * 2003-12-10 2006-08-23 MERCK PATENT GmbH Diacylhydrazine derivatives
US7102001B2 (en) 2003-12-12 2006-09-05 Bristol-Myers Squibb Company Process for preparing pyrrolotriazine
RU2006126791A (ru) * 2003-12-23 2008-01-27 Новартис АГ (CH) Бициклические гетероциклические ингибиторы р-38 киназы
US7064203B2 (en) 2003-12-29 2006-06-20 Bristol Myers Squibb Company Di-substituted pyrrolotriazine compounds
MY145634A (en) 2003-12-29 2012-03-15 Bristol Myers Squibb Co Pyrrolotriazine compounds as kinase inhibitors
US7459562B2 (en) * 2004-04-23 2008-12-02 Bristol-Myers Squibb Company Monocyclic heterocycles as kinase inhibitors
TW200538453A (en) * 2004-04-26 2005-12-01 Bristol Myers Squibb Co Bicyclic heterocycles as kinase inhibitors
US7102002B2 (en) * 2004-06-16 2006-09-05 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
US7173031B2 (en) * 2004-06-28 2007-02-06 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
US7439246B2 (en) * 2004-06-28 2008-10-21 Bristol-Myers Squibb Company Fused heterocyclic kinase inhibitors
US7432373B2 (en) * 2004-06-28 2008-10-07 Bristol-Meyers Squibb Company Processes and intermediates useful for preparing fused heterocyclic kinase inhibitors
TW200600513A (en) 2004-06-30 2006-01-01 Bristol Myers Squibb Co A method for preparing pyrrolotriazine compounds
US7253167B2 (en) 2004-06-30 2007-08-07 Bristol-Myers Squibb Company Tricyclic-heteroaryl compounds useful as kinase inhibitors
US7102003B2 (en) 2004-07-01 2006-09-05 Bristol-Myers Squibb Company Pyrrolotriazine compounds
US7504521B2 (en) 2004-08-05 2009-03-17 Bristol-Myers Squibb Co. Methods for the preparation of pyrrolotriazine compounds
PE20060421A1 (es) * 2004-08-12 2006-06-01 Bristol Myers Squibb Co Procedimiento para preparar un compuesto de pirrolotriazina anilina como inhibidores de cinasa
US7151176B2 (en) 2004-10-21 2006-12-19 Bristol-Myers Squibb Company Pyrrolotriazine compounds
CN101035791B (zh) * 2004-10-26 2010-12-08 诺瓦提斯公司 作为c-JUN N末端激酶（JNK）和P-38激酶的抑制剂的吡咯并[1,2-D][1,2,4]三嗪
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