SI1480985T1 - Salt of benzosulfonic acid containing clopidogrel and use thereof for the production of pharmaceutical formulations - Google Patents
Salt of benzosulfonic acid containing clopidogrel and use thereof for the production of pharmaceutical formulationsInfo
- Publication number
- SI1480985T1 SI1480985T1 SI200430001T SI200430001T SI1480985T1 SI 1480985 T1 SI1480985 T1 SI 1480985T1 SI 200430001 T SI200430001 T SI 200430001T SI 200430001 T SI200430001 T SI 200430001T SI 1480985 T1 SI1480985 T1 SI 1480985T1
- Authority
- SI
- Slovenia
- Prior art keywords
- clopidogrel
- salt
- production
- pharmaceutical formulations
- acid containing
- Prior art date
Links
- GKTWGGQPFAXNFI-HNNXBMFYSA-N clopidogrel Chemical compound C1([C@H](N2CC=3C=CSC=3CC2)C(=O)OC)=CC=CC=C1Cl GKTWGGQPFAXNFI-HNNXBMFYSA-N 0.000 title abstract 7
- 239000005552 B01AC04 - Clopidogrel Substances 0.000 title abstract 6
- 229960003009 clopidogrel Drugs 0.000 title abstract 6
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 239000002253 acid Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 6
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 2
- 239000003463 adsorbent Substances 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 238000001556 precipitation Methods 0.000 abstract 2
- 101000783577 Dendroaspis angusticeps Thrombostatin Proteins 0.000 abstract 1
- 101000783578 Dendroaspis jamesoni kaimosae Dendroaspin Proteins 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 229940127219 anticoagulant drug Drugs 0.000 abstract 1
- 229940127218 antiplatelet drug Drugs 0.000 abstract 1
- 230000001966 cerebroprotective effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 239000000106 platelet aggregation inhibitor Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4743—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/29—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10305984A DE10305984A1 (de) | 2003-02-13 | 2003-02-13 | Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen |
| EP04700011A EP1480985B1 (de) | 2003-02-13 | 2004-02-13 | Salz der benzolsulfonsäure mit clopidogrel und dessen verwendung zur herstellung pharmazeutischer formulierungen |
| PCT/EP2004/001369 WO2004072084A1 (de) | 2003-02-13 | 2004-02-13 | Salz der benzolsulfonsäure mit clopidogrel und dessen verwendung zur herstellung pharmazeutischer formulierungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1480985T1 true SI1480985T1 (en) | 2005-06-30 |
Family
ID=32797377
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200430001T SI1480985T1 (en) | 2003-02-13 | 2004-02-13 | Salt of benzosulfonic acid containing clopidogrel and use thereof for the production of pharmaceutical formulations |
| SI200430313T SI1592694T1 (sl) | 2003-02-13 | 2004-02-13 | Delci aktivne snovi s klopidogrelom ali njegovo farmacevtsko prenosljivo soljo |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200430313T SI1592694T1 (sl) | 2003-02-13 | 2004-02-13 | Delci aktivne snovi s klopidogrelom ali njegovo farmacevtsko prenosljivo soljo |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20050256152A1 (xx) |
| EP (4) | EP1586575A3 (xx) |
| JP (1) | JP2006515338A (xx) |
| KR (3) | KR100805176B1 (xx) |
| AT (3) | ATE290535T1 (xx) |
| BR (1) | BRPI0407430A (xx) |
| CA (2) | CA2468089A1 (xx) |
| DE (5) | DE10305984A1 (xx) |
| DK (2) | DK1592694T3 (xx) |
| ES (2) | ES2236679T3 (xx) |
| MX (1) | MXPA05007557A (xx) |
| PL (2) | PL373512A1 (xx) |
| PT (2) | PT1480985E (xx) |
| SI (2) | SI1480985T1 (xx) |
| WO (2) | WO2004072085A2 (xx) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002051412A1 (fr) * | 2000-12-25 | 2002-07-04 | Sankyo Company, Limited | Compositions medicales contenant de l'aspirine |
| DE10305984A1 (de) | 2003-02-13 | 2004-09-02 | Helm Ag | Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen |
| DE04770646T1 (de) | 2003-04-25 | 2011-12-08 | Cadila Healthcare Ltd. | Salze von clopidogrel und herstellungsverfahren |
| CA2676121A1 (en) * | 2003-11-03 | 2005-07-14 | Cadila Healthcare Limited | Processes for preparing different forms of (s)-(+)-clopidogrel bisulfate |
| CN1922188A (zh) * | 2004-02-24 | 2007-02-28 | 齐格弗里德通用国际股份公司 | 氯吡格雷之药学可接受的盐 |
| NZ551153A (en) * | 2004-04-09 | 2009-10-30 | Hanmi Pharm Ind Co Ltd | Crystalline clopidogrel naphthalenesulfonate or hydrate thereof, method for preparing same and pharmaceutical composition containing same |
| KR100563455B1 (ko) * | 2004-04-09 | 2006-03-23 | 한미약품 주식회사 | 결정성 클로피도그렐 나프탈렌술폰산염 또는 이의 수화물,이의 제조방법 및 이를 함유하는 약학적 조성물 |
| EP1756116A1 (en) * | 2004-04-20 | 2007-02-28 | Sanofi-Aventis | Polymorphic forms of methyl(+)-(s)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4h) acetate hydrobromide, clopidrogel hydrobromide |
| UA84335C2 (ru) * | 2004-04-20 | 2008-10-10 | Санофи Авентис | Клопидогрель и его полиморфные формы |
| WO2006044548A2 (en) * | 2004-10-14 | 2006-04-27 | Dr. Reddy's Laboratories Ltd. | Clopidogrel compositions |
| TWI358407B (en) * | 2005-06-22 | 2012-02-21 | Lundbeck & Co As H | Crystalline base of escitalopram and orodispersibl |
| ES2391410T3 (es) * | 2005-09-05 | 2012-11-26 | Cadila Healthcare Limited | Procedimientos para la preparación de diferentes formas de (s)-(+)-clopidogrel besilato |
| WO2007054968A2 (en) * | 2005-09-20 | 2007-05-18 | Torrent Pahrmaceuticals Limited | Novel pharmaceutical compositions of clopidogrel mesylate |
| CN101253179B (zh) * | 2005-09-21 | 2010-12-29 | 株式会社钟根堂 | S-氯吡格雷的树脂酸盐复合物及其制备方法 |
| KR100791687B1 (ko) * | 2006-02-27 | 2008-01-03 | 채종근 | 결정성 클로피도그렐 설포살리실산 염을 포함하는 제제 |
| KR100945062B1 (ko) * | 2006-03-22 | 2010-03-05 | 한미약품 주식회사 | 클로피도그렐 1,5-나프탈렌디술폰산염 및 이의 수화물의제조방법 |
| KR100834967B1 (ko) * | 2006-08-11 | 2008-06-03 | 에스케이케미칼주식회사 | 여액의 라세미화 반응에 의한 ｓ-(＋)-클로피도그렐의고수율 제조방법 |
| EP1900358A1 (en) * | 2006-09-16 | 2008-03-19 | Cimex Pharma AG | Pharmaceutical formulations comprising clopidogrel |
| ATE498626T1 (de) * | 2006-09-25 | 2011-03-15 | Adamed Sp Zoo | Neues clopidogrel-salz und seine kristallinen formen |
| CN100400035C (zh) * | 2006-10-18 | 2008-07-09 | 深圳信立泰药业股份有限公司 | 氯吡格雷硫酸盐的固体制剂及其制备方法 |
| US20100062066A1 (en) * | 2006-11-14 | 2010-03-11 | Acusphere, Inc | Formulations of Tetrahydropyridine Antiplatelet Agents for Parenteral or Oral Administration |
| EP2089396B1 (en) | 2006-11-24 | 2011-06-22 | Cadila Healthcare Limited | A process for preparing (s)-(+)-clopidogrel base and its salts |
| WO2008081473A2 (en) * | 2006-12-29 | 2008-07-10 | Cadila Healthcare Limited | Process for preparing clopidogrel |
| DK2152078T3 (da) | 2007-04-27 | 2021-02-08 | Cydex Pharmaceuticals Inc | Formuleringer indeholdende clopidogrel og sulfoalkylethercyclodextrin og anvendelsesfremgangsmåder |
| KR20090022616A (ko) * | 2007-08-31 | 2009-03-04 | 한올제약주식회사 | 베실산클로피도그렐 함유 경구투여용 약제 |
| KR100920932B1 (ko) * | 2007-12-05 | 2009-10-20 | 한림제약(주) | 결정형의 클로피도그렐 벤젠술폰산염의 제조방법 |
| EP2107061A1 (en) | 2008-04-02 | 2009-10-07 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of optically enriched clopidogrel |
| CN102625658B (zh) | 2009-05-13 | 2015-01-28 | 锡德克斯药物公司 | 包含普拉格雷和环糊精衍生物的药物组合物及其制备和使用方法 |
| WO2012123958A1 (en) | 2011-02-14 | 2012-09-20 | Cadila Healthcare Limited | Highly pure salts of clopidogrel free of genotoxic impurities |
| CN102199161B (zh) * | 2011-03-30 | 2013-07-03 | 天津红日药业股份有限公司 | 一种苯磺酸氯吡格雷晶型ⅰ及其制备方法和用途 |
| CN102285996A (zh) * | 2011-03-30 | 2011-12-21 | 天津红日药业股份有限公司 | 一种苯磺酸氯吡格雷晶型ⅱ及其制备方法和用途 |
| HUP1400294A2 (hu) | 2014-06-13 | 2015-12-28 | Skillpharm Kft | Clopidogrel új alkalmazása |
| CN104193762B (zh) * | 2014-08-04 | 2017-02-15 | 浙江车头制药股份有限公司 | 一种制备苯磺酸氯吡格雷晶型ⅲ的方法 |
| CN115327005B (zh) * | 2022-08-12 | 2024-01-26 | 成都施贝康生物医药科技有限公司 | 一种氧化氯吡格雷有关物质的检测方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2530247B1 (fr) * | 1982-07-13 | 1986-05-16 | Sanofi Sa | Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique |
| FR2623810B2 (fr) * | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
| FR2740686B1 (fr) * | 1995-11-03 | 1998-01-16 | Sanofi Sa | Formulation pharmaceutique lyophilisee stable |
| US6509348B1 (en) * | 1998-11-03 | 2003-01-21 | Bristol-Myers Squibb Company | Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination |
| WO2000054811A1 (fr) * | 1999-03-17 | 2000-09-21 | Daiichi Pharmaceutical Co., Ltd. | Compositions medicamenteuses |
| DE10109763A1 (de) * | 2001-02-28 | 2002-09-05 | Gruenenthal Gmbh | Pharmazeutische Salze |
| DE10153078A1 (de) * | 2001-10-30 | 2003-05-22 | Degussa | Verwendung von Granulaten auf Basis von pyrogen hergestelltem Siliciumdioxid in pharmazeutischen Zusammensetzungen |
| IL166593A0 (en) * | 2002-08-02 | 2006-01-15 | Racemization and enantiomer separation of clopidogrel | |
| DE10305984A1 (de) | 2003-02-13 | 2004-09-02 | Helm Ag | Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen |
| DE04770646T1 (de) * | 2003-04-25 | 2011-12-08 | Cadila Healthcare Ltd. | Salze von clopidogrel und herstellungsverfahren |
-
2003
- 2003-02-13 DE DE10305984A patent/DE10305984A1/de not_active Withdrawn
-
2004
- 2004-02-13 ES ES04700011T patent/ES2236679T3/es not_active Expired - Lifetime
- 2004-02-13 EP EP05009789A patent/EP1586575A3/de not_active Withdrawn
- 2004-02-13 DK DK04710847T patent/DK1592694T3/da active
- 2004-02-13 DE DE202004021381U patent/DE202004021381U1/de not_active Ceased
- 2004-02-13 JP JP2006500030A patent/JP2006515338A/ja active Pending
- 2004-02-13 WO PCT/EP2004/001370 patent/WO2004072085A2/de active IP Right Grant
- 2004-02-13 KR KR1020047016562A patent/KR100805176B1/ko active IP Right Grant
- 2004-02-13 AT AT04700011T patent/ATE290535T1/de not_active IP Right Cessation
- 2004-02-13 SI SI200430001T patent/SI1480985T1/xx unknown
- 2004-02-13 DE DE502004003680T patent/DE502004003680D1/de not_active Expired - Lifetime
- 2004-02-13 PT PT04700011T patent/PT1480985E/pt unknown
- 2004-02-13 DE DE502004000002T patent/DE502004000002D1/de not_active Revoked
- 2004-02-13 PL PL04373512A patent/PL373512A1/xx not_active Application Discontinuation
- 2004-02-13 MX MXPA05007557A patent/MXPA05007557A/es active IP Right Grant
- 2004-02-13 SI SI200430313T patent/SI1592694T1/sl unknown
- 2004-02-13 BR BR0407430-0A patent/BRPI0407430A/pt not_active IP Right Cessation
- 2004-02-13 DE DE202004021399U patent/DE202004021399U1/de not_active Expired - Lifetime
- 2004-02-13 AT AT05009790T patent/ATE512153T1/de active
- 2004-02-13 PL PL378572A patent/PL378572A1/pl not_active Application Discontinuation
- 2004-02-13 KR KR10-2004-7016868A patent/KR20050008692A/ko not_active Application Discontinuation
- 2004-02-13 EP EP05009790A patent/EP1595884B1/de not_active Expired - Lifetime
- 2004-02-13 PT PT04710847T patent/PT1592694E/pt unknown
- 2004-02-13 WO PCT/EP2004/001369 patent/WO2004072084A1/de active Application Filing
- 2004-02-13 AT AT04710847T patent/ATE361305T1/de active
- 2004-02-13 KR KR1020067018596A patent/KR20060103472A/ko not_active Application Discontinuation
- 2004-02-13 DK DK04700011T patent/DK1480985T3/da active
- 2004-02-13 CA CA002468089A patent/CA2468089A1/en not_active Abandoned
- 2004-02-13 EP EP04710847A patent/EP1592694B1/de not_active Revoked
- 2004-02-13 EP EP04700011A patent/EP1480985B1/de not_active Revoked
- 2004-02-13 ES ES04710847T patent/ES2282848T3/es not_active Expired - Lifetime
- 2004-02-13 CA CA002481848A patent/CA2481848C/en not_active Expired - Fee Related
- 2004-02-13 US US10/510,578 patent/US20050256152A1/en not_active Abandoned
-
2005
- 2005-04-25 US US11/113,467 patent/US20050203122A1/en not_active Abandoned
Also Published As
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