MXPA05010104A - Polvo cristalino de trihidrato de amoxicilina. - Google Patents

Polvo cristalino de trihidrato de amoxicilina.

Info

Publication number
MXPA05010104A
MXPA05010104A MXPA05010104A MXPA05010104A MXPA05010104A MX PA05010104 A MXPA05010104 A MX PA05010104A MX PA05010104 A MXPA05010104 A MX PA05010104A MX PA05010104 A MXPA05010104 A MX PA05010104A MX PA05010104 A MXPA05010104 A MX PA05010104A
Authority
MX
Mexico
Prior art keywords
amoxicillin trihydrate
crystalline
powder
trihydrate powder
crystalline amoxicillin
Prior art date
Application number
MXPA05010104A
Other languages
English (en)
Inventor
Johannus Anthonius M Everardus
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45007138&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA05010104(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of MXPA05010104A publication Critical patent/MXPA05010104A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Abstract

La invencion se refiere a un polvo cristalino de trihidrato de amoxicilina con una densidad aparente mayor de 0.45g/ml. La invencion se refiere tambien a un proceso para preparar polvo cristalino de trihidrato de amoxicilina, donde dicho proceso comprende: cristalizar el trihidrato de amoxicilina desde una solucion que contiene amoxicilina disuelta; separar los cristales de dicha solucion; y secar los cristales separados, para dar un polvo cristalino con una densidad aparente mayor de 0.45g/ml.
MXPA05010104A 2003-03-21 2004-03-19 Polvo cristalino de trihidrato de amoxicilina. MXPA05010104A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US45618703P 2003-03-21 2003-03-21
US45618803P 2003-03-21 2003-03-21
EP03100731 2003-03-21
EP03100732 2003-03-21
PCT/EP2004/002989 WO2004082661A1 (en) 2003-03-21 2004-03-19 Crystalline amoxicillin trihydrate powder

Publications (1)

Publication Number Publication Date
MXPA05010104A true MXPA05010104A (es) 2005-11-23

Family

ID=45007138

Family Applications (2)

Application Number Title Priority Date Filing Date
MXPA05010104A MXPA05010104A (es) 2003-03-21 2004-03-19 Polvo cristalino de trihidrato de amoxicilina.
MXPA05010102A MXPA05010102A (es) 2003-03-21 2004-03-19 Trihidrato de amoxicilina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MXPA05010102A MXPA05010102A (es) 2003-03-21 2004-03-19 Trihidrato de amoxicilina.

Country Status (14)

Country Link
US (1) US20060172987A1 (es)
EP (2) EP1808166A1 (es)
JP (2) JP4949827B2 (es)
CN (2) CN102260278B (es)
AT (1) ATE362359T1 (es)
BR (2) BRPI0408568A (es)
CY (1) CY1106809T1 (es)
DE (1) DE602004006507T2 (es)
ES (1) ES2286627T3 (es)
MX (2) MXPA05010104A (es)
PL (1) PL1610766T3 (es)
PT (1) PT1610766E (es)
SI (1) SI1610766T1 (es)
WO (3) WO2004082661A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7534781B2 (en) * 2003-03-21 2009-05-19 Dsm Ip Assets B.V. Crystalline amoxicillin trihydrate powder
WO2004082661A1 (en) * 2003-03-21 2004-09-30 Dsm Ip Assets B.V. Crystalline amoxicillin trihydrate powder
CN101965187B (zh) * 2007-05-21 2012-11-21 东丽株式会社 结晶性微粉化粒子
US7985791B1 (en) 2008-02-22 2011-07-26 Lords Additives LLC Incorporation of SBP and ulexite into composites
EP2778171A1 (en) * 2013-03-15 2014-09-17 Synbias Pharma Ltd. Crystalline monohydrate of epirubicin hydrochloride
CN103145733B (zh) * 2013-03-20 2014-02-26 四川省惠达药业有限公司 一种阿莫西林化合物及该化合物和克拉维酸钾的药物组合物
US9820943B2 (en) * 2013-09-03 2017-11-21 Dsm Sinochem Pharmaceuticals Netherlands B.V. Micronized amoxicillin
CN104059086B (zh) * 2014-06-19 2016-04-13 河南牧翔动物药业有限公司 一种阿莫西林晶体及其制备方法
CN104099396B (zh) * 2014-07-22 2016-03-23 石药集团中诺药业（石家庄）有限公司 一种直通法制备阿莫西林的工艺
WO2017186864A1 (en) 2016-04-27 2017-11-02 Sandoz Ag Enzymatic process for the production of beta-lactam antibiotics in the presence of particulate inoculum
CN109867687B (zh) * 2017-12-05 2021-08-17 上海朝瑞化工有限公司 一种高水溶性阿莫西林及其制备方法
CN111518119B (zh) * 2020-05-26 2021-12-21 联邦制药(内蒙古)有限公司 一种阿莫西林连续结晶工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1532672A (en) * 1976-07-20 1978-11-15 Bristol Myers Co Process for the preparation of amoxicillin trihydrate
JPS5583789A (en) * 1978-12-18 1980-06-24 Bristol Myers Co Preparation of penicillin
JPS6052751B2 (ja) * 1981-04-21 1985-11-21 富山化学工業株式会社 新規な結晶形を有するセフアレキシン１水和物
WO1994017800A1 (en) * 1993-02-15 1994-08-18 Gist-Brocades B.V. AN IMPROVED β-LACTAM ANTIBIOTIC COMPOSITION
GB9423459D0 (en) * 1994-11-21 1995-01-11 Biochemie Gmbh Silylation process
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
TR200000529T2 (tr) * 1997-08-29 2000-08-21 Dsm N.V. İçinde eksipiyan olmayan granüller
US20020137926A1 (en) * 1998-06-01 2002-09-26 Smithkline Beecham Corporation Process for preparing crystalline salts of amoxycillin
ES2215628T5 (es) * 1999-04-01 2011-11-28 Dsm Ip Assets B.V. Aglomerados obtenidos por cristalización.
AT412213B (de) * 2000-05-30 2004-11-25 Sandoz Ag Verfahren zur trocknung von amoxicillin oder amoxicillin-hältigen, oralen, festen pharmazeutischen zusammensetzungen unter verwendung eines gases mit einer definierten gasfeuchte
WO2004082661A1 (en) * 2003-03-21 2004-09-30 Dsm Ip Assets B.V. Crystalline amoxicillin trihydrate powder

Also Published As

Publication number Publication date
WO2004082661A1 (en) 2004-09-30
WO2004082663A1 (en) 2004-09-30
CN102260278A (zh) 2011-11-30
SI1610766T1 (sl) 2007-10-31
JP4949826B2 (ja) 2012-06-13
EP1808166A1 (en) 2007-07-18
DE602004006507T2 (de) 2008-01-31
PT1610766E (pt) 2007-08-01
EP1610766A1 (en) 2006-01-04
ATE362359T1 (de) 2007-06-15
JP2006523188A (ja) 2006-10-12
PL1610766T3 (pl) 2007-08-31
DE602004006507D1 (en) 2007-06-28
CN102260278B (zh) 2015-05-06
CN1761457A (zh) 2006-04-19
BRPI0408403A (pt) 2006-03-21
WO2004082662A1 (en) 2004-09-30
EP1610766B1 (en) 2007-05-16
CN1761457B (zh) 2010-05-12
CY1106809T1 (el) 2012-05-23
JP2006520765A (ja) 2006-09-14
US20060172987A1 (en) 2006-08-03
ES2286627T3 (es) 2007-12-01
MXPA05010102A (es) 2005-11-23
BRPI0408568A (pt) 2006-03-21
JP4949827B2 (ja) 2012-06-13

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