HK1090042A1 - Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the of the same as medicaments, and medicament containing such compounds - Google Patents
Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the of the same as medicaments, and medicament containing such compoundsInfo
- Publication number
- HK1090042A1 HK1090042A1 HK06110512A HK06110512A HK1090042A1 HK 1090042 A1 HK1090042 A1 HK 1090042A1 HK 06110512 A HK06110512 A HK 06110512A HK 06110512 A HK06110512 A HK 06110512A HK 1090042 A1 HK1090042 A1 HK 1090042A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- phenyltetrahydroisoquinolines
- medicaments
- substituted
- compounds
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10312963A DE10312963A1 (en) | 2003-03-24 | 2003-03-24 | Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, their use as medicament, and medicament containing them |
| PCT/EP2004/002497 WO2004085404A1 (en) | 2003-03-24 | 2004-03-11 | Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the use of the same as medicaments, and medicament containing such compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1090042A1 true HK1090042A1 (en) | 2006-12-15 |
Family
ID=32946086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK06110512A HK1090042A1 (en) | 2003-03-24 | 2006-09-21 | Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the of the same as medicaments, and medicament containing such compounds |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1613600B1 (en) |
| JP (1) | JP2006521306A (en) |
| KR (1) | KR20050115304A (en) |
| CN (1) | CN100364978C (en) |
| AR (1) | AR043741A1 (en) |
| AU (1) | AU2004224242B2 (en) |
| BR (1) | BRPI0408744A (en) |
| CA (1) | CA2519658A1 (en) |
| DE (1) | DE10312963A1 (en) |
| HK (1) | HK1090042A1 (en) |
| HR (1) | HRP20050843A2 (en) |
| MA (1) | MA27751A1 (en) |
| ME (1) | MEP42908A (en) |
| MX (1) | MXPA05010003A (en) |
| MY (1) | MY139498A (en) |
| NO (1) | NO20054876L (en) |
| NZ (1) | NZ542608A (en) |
| PE (1) | PE20050311A1 (en) |
| RS (1) | RS20050713A (en) |
| RU (1) | RU2343147C2 (en) |
| TW (1) | TW200510321A (en) |
| WO (1) | WO2004085404A1 (en) |
| ZA (1) | ZA200506422B (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004046492A1 (en) * | 2004-09-23 | 2006-03-30 | Sanofi-Aventis Deutschland Gmbh | Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, their use as medicament, and medicament containing them |
| DE102005001411A1 (en) * | 2005-01-12 | 2006-07-27 | Sanofi-Aventis Deutschland Gmbh | Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, their use as medicament, and medicament containing them |
| DE102005033100B3 (en) * | 2005-07-15 | 2007-01-25 | Sanofi-Aventis Deutschland Gmbh | Novel 1,4-benzothiazepine-1,1-dioxide derivative with improved properties, drugs containing this compound and methods for their preparation |
| DE102005044817A1 (en) * | 2005-09-20 | 2007-03-22 | Sanofi-Aventis Deutschland Gmbh | Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, their use as medicament, and medicament containing them |
| DE102006012544A1 (en) * | 2006-03-18 | 2007-09-27 | Sanofi-Aventis | Substituted 1-amino-4-phenyl-dihydroisoquinolines, process for their preparation, their use as medicament, and medicament containing them |
| AU2007263809B2 (en) * | 2006-06-29 | 2013-07-18 | F. Hoffmann-La Roche Ag | Tetrazole-substituted arylamides |
| JPWO2008004610A1 (en) * | 2006-07-05 | 2009-12-03 | 国立大学法人 東京大学 | Methods for treating nonsense mutation hereditary diseases |
| MX2010012242A (en) * | 2008-05-19 | 2010-12-06 | Actelion Pharmaceuticals Ltd | Tetrahydroisoquinolines as antimalarial agents. |
| WO2018129556A1 (en) * | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| WO2010078449A2 (en) | 2008-12-31 | 2010-07-08 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| US10543207B2 (en) | 2008-12-31 | 2020-01-28 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| LT2748147T (en) * | 2011-08-25 | 2017-10-25 | St. Jude Children`S Research Hospital | Substituted 2-alkyl-1-oxo-n-phenyl-3-heteroaryl-1,2,3,4-tetrahydroisoquinoline-4-carboxamides for antimalarial therapies |
| SI2983667T1 (en) | 2013-04-12 | 2019-09-30 | Ardelyx, Inc. | Nhe3-binding compounds and methods for inhibiting phosphate transport |
| RU2538085C2 (en) * | 2013-05-08 | 2015-01-10 | Любовь Демьяновна Шаманская | Agent for control of exo-parasites of animals |
| ME03311B (en) * | 2014-07-25 | 2019-10-20 | Taisho Pharmaceutical Co Ltd | Phenyl tetrahydroisoquinoline compound substituted with heteroaryl |
| JP2020505333A (en) | 2017-01-09 | 2020-02-20 | アルデリックス， インコーポレイテッド | Inhibitors of NHE-mediated antiport |
| EP3565808A1 (en) | 2017-01-09 | 2019-11-13 | Ardelyx, Inc. | Compounds useful for treating gastrointestinal tract disorders |
| US10357493B2 (en) | 2017-03-10 | 2019-07-23 | Selenity Therapeutics (Bermuda), Ltd. | Metalloenzyme inhibitor compounds |
| MX2021013771A (en) * | 2019-05-16 | 2021-12-10 | Lilly Co Eli | Sodium-hydrogen exchanger 3 inhibitor compounds. |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3666763A (en) * | 1970-01-06 | 1972-05-30 | Hoffmann La Roche | 4-phenyl isoquinolines and process for preparing same |
| JPH06256311A (en) * | 1993-02-26 | 1994-09-13 | Nippon Shinyaku Co Ltd | Isoquinolinol derivative and medicine |
| DE19951702A1 (en) * | 1999-10-27 | 2001-05-03 | Aventis Pharma Gmbh | Use of 2-amino-3,4-dihydroquinazolines for the manufacture of a medicament for the treatment or prophylaxis of diseases caused by ischemic conditions |
| RU2293728C2 (en) * | 1999-11-03 | 2007-02-20 | Эймр Текнолоджи, Инк. | Derivatives of tetrahydroisoquinoline, pharmaceutical composition containing thereof, method for inhibition of synaptic uptake of dopamine and treatment method |
| ES2304984T3 (en) * | 1999-11-03 | 2008-11-01 | Amr Technology, Inc. | TETRA-HYDROISOQUINOLINAS OF ARILICA AND HETEROARILICA SUBSTITUTION AND ITS USE TO BLOCK THE RECOVERY OF NOREPINEFRINE, DOPAMINE AND SEROTONINE. |
| EP1113007A1 (en) * | 1999-12-24 | 2001-07-04 | Pfizer Inc. | Tetrahydroisoquinoline compounds as estrogen agonists/antagonists |
| ATE425968T1 (en) * | 2001-12-05 | 2009-04-15 | Sanofi Aventis Deutschland | SUBSTITUTED 4-PHENYLTETRAHYDROISOCINOLINES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICATION, AND MEDICINE CONTAINING THEM |
| DE10161767A1 (en) * | 2001-12-15 | 2003-06-26 | Merck Patent Gmbh | New 2-guanidino-4-heterocyclyl-quinazoline derivatives, useful as sodium-proton antiporter subtype III inhibitors for treating e.g. respiratory, renal, ischemic or lipid metabolism disorders |
| DE10163914A1 (en) * | 2001-12-22 | 2003-07-03 | Aventis Pharma Gmbh | Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as medicament, and medicament containing them |
| DE10163992A1 (en) * | 2001-12-24 | 2003-07-03 | Merck Patent Gmbh | 4-aryl-quinazolines |
-
2003
- 2003-03-24 DE DE10312963A patent/DE10312963A1/en not_active Withdrawn
-
2004
- 2004-03-10 PE PE2004000261A patent/PE20050311A1/en not_active Application Discontinuation
- 2004-03-11 KR KR1020057017892A patent/KR20050115304A/en not_active Application Discontinuation
- 2004-03-11 JP JP2006504636A patent/JP2006521306A/en active Pending
- 2004-03-11 EP EP04719379.2A patent/EP1613600B1/en not_active Expired - Lifetime
- 2004-03-11 RS YUP-2005/0713A patent/RS20050713A/en unknown
- 2004-03-11 RU RU2006127170/04A patent/RU2343147C2/en not_active IP Right Cessation
- 2004-03-11 NZ NZ542608A patent/NZ542608A/en unknown
- 2004-03-11 MX MXPA05010003A patent/MXPA05010003A/en active IP Right Grant
- 2004-03-11 BR BRPI0408744-5A patent/BRPI0408744A/en not_active IP Right Cessation
- 2004-03-11 WO PCT/EP2004/002497 patent/WO2004085404A1/en active Application Filing
- 2004-03-11 AU AU2004224242A patent/AU2004224242B2/en not_active Ceased
- 2004-03-11 ME MEP-429/08A patent/MEP42908A/en unknown
- 2004-03-11 CN CNB2004800078710A patent/CN100364978C/en not_active Expired - Fee Related
- 2004-03-11 CA CA002519658A patent/CA2519658A1/en not_active Abandoned
- 2004-03-22 TW TW093107600A patent/TW200510321A/en unknown
- 2004-03-22 AR ARP040100940A patent/AR043741A1/en unknown
- 2004-03-23 MY MYPI20041021A patent/MY139498A/en unknown
-
2005
- 2005-08-11 ZA ZA200506422A patent/ZA200506422B/en unknown
- 2005-09-23 HR HR20050843A patent/HRP20050843A2/en not_active Application Discontinuation
- 2005-09-23 MA MA28514A patent/MA27751A1/en unknown
- 2005-10-21 NO NO20054876A patent/NO20054876L/en unknown
-
2006
- 2006-09-21 HK HK06110512A patent/HK1090042A1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050115304A (en) | 2005-12-07 |
| CA2519658A1 (en) | 2004-10-07 |
| BRPI0408744A (en) | 2006-04-18 |
| RU2343147C2 (en) | 2009-01-10 |
| AU2004224242B2 (en) | 2010-03-18 |
| JP2006521306A (en) | 2006-09-21 |
| DE10312963A1 (en) | 2004-10-07 |
| AR043741A1 (en) | 2005-08-10 |
| NO20054876L (en) | 2005-12-06 |
| HRP20050843A2 (en) | 2006-09-30 |
| MY139498A (en) | 2009-10-30 |
| ZA200506422B (en) | 2007-02-28 |
| CN100364978C (en) | 2008-01-30 |
| MXPA05010003A (en) | 2005-11-17 |
| MA27751A1 (en) | 2006-02-01 |
| CN1798737A (en) | 2006-07-05 |
| EP1613600B1 (en) | 2015-12-23 |
| PE20050311A1 (en) | 2005-06-06 |
| AU2004224242A1 (en) | 2004-10-07 |
| MEP42908A (en) | 2011-02-10 |
| TW200510321A (en) | 2005-03-16 |
| RU2006127170A (en) | 2008-02-10 |
| NO20054876D0 (en) | 2005-10-21 |
| RS20050713A (en) | 2007-11-15 |
| NZ542608A (en) | 2009-07-31 |
| EP1613600A1 (en) | 2006-01-11 |
| WO2004085404A1 (en) | 2004-10-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1090042A1 (en) | Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the of the same as medicaments, and medicament containing such compounds | |
| IL173204A0 (en) | Novel cyanopyrrolidides, methods for the production thereof, and use of the same as medicaments | |
| ZA200500086B (en) | Novel carboxamide compounds having an MCH-antagonistic effect, medicaments containing said compounds, and method for the production thereof | |
| PL378065A1 (en) | Substituted n-arylheterocycles, method for production and use thereof as medicaments | |
| IL191926A0 (en) | Novel thiophenylglycoside derivatives, methods for production thereof, medicaments comprising said compounds and use thereof | |
| IL163831A0 (en) | Derivatives of aminoindazoles, method of preparation and intermediates of the method as drugs pharmaceutical compounds containing | |
| HK1100409A1 (en) | Substituted tetrahydro-2h-isoquinolin-1-one derivatives, method for the production thereof, and use of the same as medicaments | |
| HK1081965A1 (en) | Pyridopyrimidinone compounds, method for production thereof and medicaments comprising the same | |
| IL179757A (en) | Fluoroglycoside derivatives of pyrazoles, medicaments containing these compounds, process for preparing such medicaments and the use thereof | |
| HUP0401329A2 (en) | Aminoalkyl-substituted aromatic bicyclic compounds, method for the production thereof and their use as medicaments | |
| AU2003282094A1 (en) | Novel dihydroxy-methylphenyl derivatives, method for the production and use thereof as medicaments | |
| AU2003257465A1 (en) | Substituted diaryl heterocycles, method for the production and use thereof as medicaments | |
| IL175127A0 (en) | Novel tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same | |
| HK1076095A1 (en) | Pentafluorosulfanyl-benzoylguanidine, method for the production thereof and its utilization as medicament or diagnostic agent and medicament containing same | |
| HRP20041203A2 (en) | Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof | |
| AU2003226806A1 (en) | Bicyclic heterocycles, medicaments containing these compounds, their use, and method for the production thereof | |
| PL377741A1 (en) | Diarylcycloalkyl derivatives, method for their production and their use as medicaments | |
| AU2003255612A8 (en) | Novel multimeric molecules, the preparation method thereof and use of same for the preparation of medicaments | |
| AU2003231920A8 (en) | Antiinfectve compounds, process for their preparation and pharmaceutical compositions containing them | |
| IL173918A0 (en) | Substituted thienoimidazoles, method for production and use thereof as medicament or diagnostic and medicaments comprising the same | |
| WO2004022542A3 (en) | Substituted 1,2,3,4-tetrahydroquinoline derivatives | |
| AU2003294952A8 (en) | 3,3-dimethyl-8-oxoisoquinolines for medical purposes, methods for the production thereof, medicaments containing said compounds and the use of the same | |
| HUP0302440A3 (en) | Aminoquinoline derivatives, process for producing them and pharmaceutical compositions containing them | |
| PL366975A1 (en) | Pharmaceutical composition containing oxalyplatinum as well as method for its manufacture | |
| AU2003232684A8 (en) | Pyrazole-3-one derivative, method for preparing the same, and pharmaceutical composition containing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20120311 |