SI1220856T1 - Pyrazolo(4,3-d)pyrimidine derivatives - Google Patents

Pyrazolo(4,3-d)pyrimidine derivatives

Info

Publication number
SI1220856T1
SI1220856T1 SI200030593T SI200030593T SI1220856T1 SI 1220856 T1 SI1220856 T1 SI 1220856T1 SI 200030593 T SI200030593 T SI 200030593T SI 200030593 T SI200030593 T SI 200030593T SI 1220856 T1 SI1220856 T1 SI 1220856T1
Authority
SI
Slovenia
Prior art keywords
pyrazolo
pyrimidine derivatives
pyrimidine
derivatives
Prior art date
Application number
SI200030593T
Other languages
English (en)
Slovenian (sl)
Inventor
Mark Edward Bunnage
Keith Michael Devries
Laurence James Harris
Philip Charles Levett
John Paul Mathias
Joanna Teresa Negri
Stephen Derek Albert Street
Albert Shaw Wood
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9924063.2A external-priority patent/GB9924063D0/en
Priority claimed from GB0018656A external-priority patent/GB0018656D0/en
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of SI1220856T1 publication Critical patent/SI1220856T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI200030593T 1999-10-11 2000-10-11 Pyrazolo(4,3-d)pyrimidine derivatives SI1220856T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9924063.2A GB9924063D0 (en) 1999-10-11 1999-10-11 Pharmaceutically active compounds
GB0018656A GB0018656D0 (en) 2000-07-28 2000-07-28 Pharmaceutically active compounds
EP00966347A EP1220856B1 (en) 1999-10-11 2000-10-11 Pyrazolo[4,3-d]pyrimidine derivatives
PCT/IB2000/001457 WO2001027113A2 (en) 1999-10-11 2000-10-11 PYRAZOLO `4,3-d! PYRIMIDINE DERIVATIVES

Publications (1)

Publication Number Publication Date
SI1220856T1 true SI1220856T1 (en) 2005-06-30

Family

ID=26244757

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030593T SI1220856T1 (en) 1999-10-11 2000-10-11 Pyrazolo(4,3-d)pyrimidine derivatives

Country Status (49)

Country Link
US (4) US6677335B1 (pt)
EP (1) EP1220856B1 (pt)
JP (1) JP3834236B2 (pt)
KR (1) KR100549152B1 (pt)
CN (3) CN100383141C (pt)
AP (1) AP1238A (pt)
AT (1) ATE284404T1 (pt)
AU (1) AU779065B2 (pt)
BG (1) BG106678A (pt)
BR (1) BR0014698A (pt)
CA (1) CA2387357C (pt)
CO (1) CO5251477A1 (pt)
CR (2) CR6617A (pt)
CU (1) CU23198A3 (pt)
CZ (1) CZ20021158A3 (pt)
DE (1) DE60016615T2 (pt)
DK (1) DK1220856T3 (pt)
DZ (1) DZ3220A1 (pt)
EA (1) EA004982B1 (pt)
EE (1) EE05181B1 (pt)
EG (1) EG24411A (pt)
ES (1) ES2232502T3 (pt)
GE (2) GEP20033142B (pt)
GT (1) GT200000171A (pt)
HK (3) HK1050367A1 (pt)
HR (1) HRP20020317B1 (pt)
HU (1) HUP0203450A3 (pt)
IL (2) IL149026A0 (pt)
IN (4) IN2002MU00385A (pt)
IS (1) IS2181B (pt)
MA (1) MA26825A1 (pt)
MX (1) MX228340B (pt)
MY (1) MY130319A (pt)
NO (1) NO322856B1 (pt)
NZ (1) NZ518078A (pt)
OA (1) OA12061A (pt)
PA (1) PA8504501A1 (pt)
PE (1) PE20010737A1 (pt)
PH (1) PH12000002783B1 (pt)
PL (1) PL357536A1 (pt)
PT (1) PT1220856E (pt)
RS (1) RS50476B (pt)
SI (1) SI1220856T1 (pt)
SK (1) SK4602002A3 (pt)
SV (1) SV2002000195A (pt)
TN (1) TNSN00199A1 (pt)
TR (1) TR200200989T2 (pt)
TW (1) TWI265925B (pt)
WO (1) WO2001027113A2 (pt)

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GB0000561D0 (en) * 2000-01-11 2000-03-01 Pfizer Ltd Treatment of diabetic ulcers
CA2406947A1 (en) * 2000-04-19 2001-10-25 Johns Hopkins University Methods for prevention and treatment of gastrointestinal disorders
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