SI1105409T1 - Zascita endogenih peptidov pred peptidazno ucinkovitostjo s konjugacijo na krvne komponente - Google Patents
Zascita endogenih peptidov pred peptidazno ucinkovitostjo s konjugacijo na krvne komponenteInfo
- Publication number
- SI1105409T1 SI1105409T1 SI200030836T SI200030836T SI1105409T1 SI 1105409 T1 SI1105409 T1 SI 1105409T1 SI 200030836 T SI200030836 T SI 200030836T SI 200030836 T SI200030836 T SI 200030836T SI 1105409 T1 SI1105409 T1 SI 1105409T1
- Authority
- SI
- Slovenia
- Prior art keywords
- peptide
- terminus
- peptidase activity
- amino acid
- protection
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/645—Secretins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57545—Neuropeptide Y
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13440699P | 1999-05-17 | 1999-05-17 | |
US15340699P | 1999-09-10 | 1999-09-10 | |
US15978399P | 1999-10-15 | 1999-10-15 | |
PCT/US2000/013576 WO2000069900A2 (en) | 1999-05-17 | 2000-05-17 | Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components |
EP00936023A EP1105409B1 (en) | 1999-05-17 | 2000-05-17 | Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1105409T1 true SI1105409T1 (sl) | 2006-06-30 |
Family
ID=27384581
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200030836T SI1105409T1 (sl) | 1999-05-17 | 2000-05-17 | Zascita endogenih peptidov pred peptidazno ucinkovitostjo s konjugacijo na krvne komponente |
Country Status (11)
Country | Link |
---|---|
EP (5) | EP1105409B1 (sl) |
JP (6) | JP4217004B2 (sl) |
AT (1) | ATE318835T1 (sl) |
AU (1) | AU765753B2 (sl) |
CA (4) | CA2499211A1 (sl) |
DE (1) | DE60026300T2 (sl) |
DK (1) | DK1105409T3 (sl) |
ES (1) | ES2257298T3 (sl) |
PT (1) | PT1105409E (sl) |
SI (1) | SI1105409T1 (sl) |
WO (1) | WO2000069900A2 (sl) |
Families Citing this family (108)
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US6887470B1 (en) | 1999-09-10 | 2005-05-03 | Conjuchem, Inc. | Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components |
US7601691B2 (en) | 1999-05-17 | 2009-10-13 | Conjuchem Biotechnologies Inc. | Anti-obesity agents |
DE60006100T2 (de) | 1999-05-17 | 2004-07-01 | Conjuchem, Inc., Montreal | Lang wirkende insulinotrope peptide |
AU2002239414A1 (en) * | 2000-11-02 | 2002-05-27 | Bristol-Myers Squibb Company | Modified plasminogen related peptide fragments and their use as angiogenesis inhibitors |
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PT1360202E (pt) * | 2001-02-16 | 2008-09-01 | Conjuchem Biotechnologies Inc | Peptídeo do tipo glucagon 2 (glp-2) de longa duração para o tratamento de doenças e distúrbios gastrointestinais |
US7736654B2 (en) | 2001-04-10 | 2010-06-15 | Agensys, Inc. | Nucleic acids and corresponding proteins useful in the detection and treatment of various cancers |
CA2444530A1 (en) * | 2001-04-18 | 2002-10-24 | The Open University | Polypeptides, derivatives and uses thereof |
US7491702B2 (en) | 2001-04-18 | 2009-02-17 | The Open University | Polypeptides related to amyloid precursor protein, pharmaceutical compositions thereof, and methods of treatment using the same |
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US20050026165A1 (en) * | 2001-05-31 | 2005-02-03 | Cindy Orser | Detection of conformationally altered proteins and prions |
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2000
- 2000-05-17 CA CA002499211A patent/CA2499211A1/en not_active Abandoned
- 2000-05-17 DK DK00936023T patent/DK1105409T3/da active
- 2000-05-17 AT AT00936023T patent/ATE318835T1/de active
- 2000-05-17 CA CA002505617A patent/CA2505617A1/en not_active Abandoned
- 2000-05-17 WO PCT/US2000/013576 patent/WO2000069900A2/en active IP Right Grant
- 2000-05-17 EP EP00936023A patent/EP1105409B1/en not_active Expired - Lifetime
- 2000-05-17 ES ES00936023T patent/ES2257298T3/es not_active Expired - Lifetime
- 2000-05-17 JP JP2000618316A patent/JP4217004B2/ja not_active Expired - Fee Related
- 2000-05-17 SI SI200030836T patent/SI1105409T1/sl unknown
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- 2000-05-17 CA CA002623458A patent/CA2623458A1/en not_active Abandoned
- 2000-05-17 PT PT00936023T patent/PT1105409E/pt unknown
- 2000-05-17 EP EP08158878A patent/EP2100901A1/en active Pending
- 2000-05-17 DE DE60026300T patent/DE60026300T2/de not_active Expired - Lifetime
- 2000-05-17 EP EP05108328A patent/EP1623994A3/en not_active Withdrawn
- 2000-05-17 AU AU51393/00A patent/AU765753B2/en not_active Ceased
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DK1105409T3 (da) | 2006-07-03 |
JP2005239736A (ja) | 2005-09-08 |
ATE318835T1 (de) | 2006-03-15 |
EP1598365A1 (en) | 2005-11-23 |
EP1623994A3 (en) | 2008-07-16 |
JP2008150384A (ja) | 2008-07-03 |
WO2000069900A9 (en) | 2002-07-04 |
DE60026300D1 (de) | 2006-04-27 |
WO2000069900A2 (en) | 2000-11-23 |
EP1105409A2 (en) | 2001-06-13 |
PT1105409E (pt) | 2006-07-31 |
CA2499211A1 (en) | 2000-11-23 |
EP2100901A1 (en) | 2009-09-16 |
CA2373680C (en) | 2008-07-29 |
JP2009079048A (ja) | 2009-04-16 |
EP1591453A1 (en) | 2005-11-02 |
DE60026300T2 (de) | 2006-11-16 |
JP4221392B2 (ja) | 2009-02-12 |
EP1623994A2 (en) | 2006-02-08 |
AU5139300A (en) | 2000-12-05 |
JP4217004B2 (ja) | 2009-01-28 |
ES2257298T3 (es) | 2006-08-01 |
JP2010168384A (ja) | 2010-08-05 |
CA2505617A1 (en) | 2000-11-23 |
CA2373680A1 (en) | 2000-11-23 |
JP2003508350A (ja) | 2003-03-04 |
EP1105409B1 (en) | 2006-03-01 |
JP2005263807A (ja) | 2005-09-29 |
AU765753B2 (en) | 2003-09-25 |
WO2000069900A3 (en) | 2001-02-15 |
CA2623458A1 (en) | 2000-11-23 |
JP4219339B2 (ja) | 2009-02-04 |
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