WO2001005420A8 - SMALL PEPTIDES AND METHODS FOR DOWNREGULATION OF IgE - Google Patents

SMALL PEPTIDES AND METHODS FOR DOWNREGULATION OF IgE

Info

Publication number
WO2001005420A8
WO2001005420A8 PCT/US2000/019496 US0019496W WO0105420A8 WO 2001005420 A8 WO2001005420 A8 WO 2001005420A8 US 0019496 W US0019496 W US 0019496W WO 0105420 A8 WO0105420 A8 WO 0105420A8
Authority
WO
WIPO (PCT)
Prior art keywords
ige
downregulation
methods
phe
small peptides
Prior art date
Application number
PCT/US2000/019496
Other languages
French (fr)
Other versions
WO2001005420A1 (en
Inventor
James Clargett
Original Assignee
Histatek Llc
James Clargett
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA002379323A priority Critical patent/CA2379323A1/en
Priority to AU63515/00A priority patent/AU6351500A/en
Priority to IL14752500A priority patent/IL147525A0/en
Priority to EA200200169A priority patent/EA200200169A1/en
Priority to KR1020027000605A priority patent/KR20020040750A/en
Priority to EP00950404A priority patent/EP1303290A4/en
Application filed by Histatek Llc, James Clargett filed Critical Histatek Llc
Priority to BR0012495-8A priority patent/BR0012495A/en
Priority to JP2001510474A priority patent/JP2003504412A/en
Priority to MXPA02000531A priority patent/MXPA02000531A/en
Publication of WO2001005420A1 publication Critical patent/WO2001005420A1/en
Publication of WO2001005420A8 publication Critical patent/WO2001005420A8/en
Priority to NO20020224A priority patent/NO20020224L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

A method for downregulating IgE levels is described. The method involves administering to a patient an IgE downregulating effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
PCT/US2000/019496 1999-07-16 2000-07-14 Small peptides and methods for downregulation of ige WO2001005420A1 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
AU63515/00A AU6351500A (en) 1999-07-16 2000-07-14 Small peptides and methods for downregulation of ige
IL14752500A IL147525A0 (en) 1999-07-16 2000-07-14 SMALL PEPTIDES AND METHODS FOR DOWNREGULATION OF IgE
EA200200169A EA200200169A1 (en) 1999-07-16 2000-07-14 SMALL PEPTIDES AND METHODS OF DECREASING IgE REGULATION
KR1020027000605A KR20020040750A (en) 1999-07-16 2000-07-14 Small peptides and methods for downregulation of IgE
EP00950404A EP1303290A4 (en) 1999-07-16 2000-07-14 Small peptides and methods for downregulation of ige
CA002379323A CA2379323A1 (en) 1999-07-16 2000-07-14 Small peptides and methods for downregulation of ige
BR0012495-8A BR0012495A (en) 1999-07-16 2000-07-14 Methods for the treatment of an indication resulting from an ige-mediated response in a mammal, for the downward regulation of an ige receptor and cd40 ligand, and for the inhibition of ige secretion by plasma cells
JP2001510474A JP2003504412A (en) 1999-07-16 2000-07-14 Small peptides and methods for down-regulating IgE
MXPA02000531A MXPA02000531A (en) 1999-07-16 2000-07-14 Small peptides and methods for downregulation of ige.
NO20020224A NO20020224L (en) 1999-07-16 2002-01-15 Small peptides and methods for down-regulation of IgE

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14453999P 1999-07-16 1999-07-16
US60/144,539 1999-07-16

Publications (2)

Publication Number Publication Date
WO2001005420A1 WO2001005420A1 (en) 2001-01-25
WO2001005420A8 true WO2001005420A8 (en) 2001-04-12

Family

ID=22509041

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/019496 WO2001005420A1 (en) 1999-07-16 2000-07-14 Small peptides and methods for downregulation of ige

Country Status (13)

Country Link
EP (1) EP1303290A4 (en)
JP (1) JP2003504412A (en)
KR (1) KR20020040750A (en)
CN (1) CN1367700A (en)
AU (1) AU6351500A (en)
BR (1) BR0012495A (en)
CA (1) CA2379323A1 (en)
EA (1) EA200200169A1 (en)
IL (1) IL147525A0 (en)
MX (1) MXPA02000531A (en)
NO (1) NO20020224L (en)
PL (1) PL352837A1 (en)
WO (1) WO2001005420A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749685A (en) * 1986-08-01 1988-06-07 Dnax Research Institute Of Molecular And Cellular Biology, Inc. Immunosuppressive peptides
CN1282253A (en) * 1997-11-13 2001-01-31 海斯塔泰克有限责任公司 Small peptides and method for treatment of asthma and inflammation
CN1341026A (en) * 1998-12-03 2002-03-20 海斯塔泰克有限责任公司 Small peptides and methods for treatment of asthma and inflammation
ES2316359T3 (en) * 1999-03-22 2009-04-16 Mowycal Lending, Llc TREATMENT WITH SMALL PEPTIDES TO INDUCE AN ANTIFIBROTIC ACTIVITY.

Also Published As

Publication number Publication date
EA200200169A1 (en) 2002-06-27
KR20020040750A (en) 2002-05-30
BR0012495A (en) 2002-06-11
PL352837A1 (en) 2003-09-08
EP1303290A1 (en) 2003-04-23
JP2003504412A (en) 2003-02-04
IL147525A0 (en) 2002-08-14
WO2001005420A1 (en) 2001-01-25
MXPA02000531A (en) 2002-07-02
NO20020224L (en) 2002-03-04
CA2379323A1 (en) 2001-01-25
NO20020224D0 (en) 2002-01-15
CN1367700A (en) 2002-09-04
AU6351500A (en) 2001-02-05
EP1303290A4 (en) 2004-12-08

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