SG92294G - Unsaturated amino-acids - Google Patents

Unsaturated amino-acids

Info

Publication number
SG92294G
SG92294G SG92294A SG92294A SG92294G SG 92294 G SG92294 G SG 92294G SG 92294 A SG92294 A SG 92294A SG 92294 A SG92294 A SG 92294A SG 92294 G SG92294 G SG 92294G
Authority
SG
Singapore
Prior art keywords
alkyl
amino
hydroxy
phosphono
pentenoic acid
Prior art date
Application number
SG92294A
Other languages
English (en)
Inventor
Christof Dr Angst
Derek Edward Dr Brundish
John Grey Dr Dingwall
Graham Eric Dr Fagg
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Priority to SG92294A priority Critical patent/SG92294G/en
Publication of SG92294G publication Critical patent/SG92294G/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3826Acyclic unsaturated acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/302Acyclic unsaturated acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32Esters thereof
    • C07F9/3205Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3217Esters of acyclic unsaturated acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4015Esters of acyclic unsaturated acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
SG92294A 1986-02-13 1994-07-11 Unsaturated amino-acids SG92294G (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG92294A SG92294G (en) 1986-02-13 1994-07-11 Unsaturated amino-acids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH57886 1986-02-13
SG92294A SG92294G (en) 1986-02-13 1994-07-11 Unsaturated amino-acids

Publications (1)

Publication Number Publication Date
SG92294G true SG92294G (en) 1995-04-28

Family

ID=4190244

Family Applications (1)

Application Number Title Priority Date Filing Date
SG92294A SG92294G (en) 1986-02-13 1994-07-11 Unsaturated amino-acids

Country Status (23)

Country Link
EP (1) EP0233154B1 (hu)
JP (2) JPH0717665B2 (hu)
KR (1) KR900003533B1 (hu)
AT (1) ATE70535T1 (hu)
AU (1) AU610493B2 (hu)
CA (1) CA1331625C (hu)
CY (1) CY1821A (hu)
DD (1) DD263775A5 (hu)
DE (1) DE3775229D1 (hu)
DK (1) DK169341B1 (hu)
ES (1) ES2038690T3 (hu)
FI (1) FI85144C (hu)
GR (1) GR3003526T3 (hu)
HK (1) HK95594A (hu)
HU (1) HU204532B (hu)
IE (1) IE59417B1 (hu)
IL (1) IL81543A0 (hu)
NO (1) NO170938C (hu)
NZ (1) NZ219255A (hu)
PH (1) PH23762A (hu)
PT (1) PT84270B (hu)
SG (1) SG92294G (hu)
ZA (1) ZA871022B (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175344A (en) * 1986-02-13 1992-12-29 Ciba-Geigy Corporation Unsaturated amino acids
PT85874B (pt) * 1986-10-09 1990-07-31 Ciba Geigy Ag Processo para a preparacao de oligo-peptidos com accao antibiotica
EP0302826A3 (de) * 1987-08-04 1991-04-03 Ciba-Geigy Ag Verfahren zur Herstellung neuer ungesättigter Aminosäureverbindungen
US5175153A (en) * 1987-11-30 1992-12-29 Warner-Lambert Company Substituted alpha-amino acids having pharmaceutical activity
US5179085A (en) * 1989-03-15 1993-01-12 Warner-Lambert Company N-substituted α-amino acids and derivatives thereof having pharmaceutical activity
ATE112282T1 (de) * 1989-04-07 1994-10-15 Ciba Geigy Ag Ungesättigte aminodicarbonsäurederivate.
US5500419A (en) * 1989-09-19 1996-03-19 Merrell Dow Pharmaceuticals Inc. NMDA antagonists
US5294734A (en) * 1989-09-26 1994-03-15 Ciba-Geigy Corp. 4-substituted 2-aminoalk-3-enoic acids
US5488140A (en) * 1989-09-26 1996-01-30 Ciba-Geigy Corporation 4-substituted 2-aminoalk-3-enoic
EP0420806B1 (de) * 1989-09-26 1995-07-05 Ciba-Geigy Ag Phosphonsäure, Verfahren zur Herstellung und Verwendung als Arzneimittelwirkstoff
US5238958A (en) * 1990-02-26 1993-08-24 Warner-Lambert Company Substituted α-amino acids having selected acidic moieties for use as excitatory amino acid antagonists in pharmaceuticals
JPH07505908A (ja) * 1992-09-28 1995-06-29 マックセチーニ、マリア ルイザ Nmda受容体のアロステリックモジュレーター
JP2009511624A (ja) * 2005-10-18 2009-03-19 サーントゥル ナシオナル ドゥ ラ ルシェルシュ シャーンティフィク (セ エン エール エス) 次亜リン酸誘導体及びその治療的用途
DE102007032669A1 (de) * 2007-07-13 2009-01-15 Clariant International Limited Alkylphosphonigsäuren, -salze und -ester, Verfahren zu deren Herstellung und ihre Verwendung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5387314A (en) * 1977-01-07 1978-08-01 Heiichi Sakai Nn14099substance
GB2104079B (en) * 1981-08-14 1985-08-21 London Polytech New aminoacid isomers, their production and their medicinal use
US4477391A (en) 1981-08-14 1984-10-16 Collins James F Amino acid isomers, their production and their medicinal use

Also Published As

Publication number Publication date
FI870558A (fi) 1987-08-14
IE870365L (en) 1987-08-13
EP0233154A2 (de) 1987-08-19
HU204532B (en) 1992-01-28
DD263775A5 (de) 1989-01-11
ATE70535T1 (de) 1992-01-15
CA1331625C (en) 1994-08-23
HK95594A (en) 1994-09-16
PT84270A (en) 1987-03-01
JPS62246586A (ja) 1987-10-27
KR900003533B1 (ko) 1990-05-21
FI85144B (fi) 1991-11-29
JPH0717665B2 (ja) 1995-03-01
ZA871022B (en) 1987-09-30
PH23762A (en) 1989-11-03
EP0233154A3 (en) 1989-06-14
JP2509465B2 (ja) 1996-06-19
IE59417B1 (en) 1994-02-23
NZ219255A (en) 1989-08-29
HUT43863A (en) 1987-12-28
DK70787D0 (da) 1987-02-12
EP0233154B1 (de) 1991-12-18
NO870577D0 (no) 1987-02-13
AU610493B2 (en) 1991-05-23
NO870577L (no) 1987-08-14
DE3775229D1 (de) 1992-01-30
DK70787A (da) 1987-08-14
NO170938B (no) 1992-09-21
FI870558A0 (fi) 1987-02-11
PT84270B (pt) 1989-09-14
ES2038690T3 (es) 1993-08-01
AU6872687A (en) 1987-08-20
FI85144C (fi) 1992-03-10
GR3003526T3 (hu) 1993-03-16
NO170938C (no) 1992-12-30
CY1821A (en) 1995-10-20
JPH07206683A (ja) 1995-08-08
IL81543A0 (en) 1987-09-16
KR870007942A (ko) 1987-09-23
DK169341B1 (da) 1994-10-10

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