SG65790G - Indole derivatives - Google Patents
Indole derivativesInfo
- Publication number
- SG65790G SG65790G SG65790A SG65790A SG65790G SG 65790 G SG65790 G SG 65790G SG 65790 A SG65790 A SG 65790A SG 65790 A SG65790 A SG 65790A SG 65790 G SG65790 G SG 65790G
- Authority
- SG
- Singapore
- Prior art keywords
- indole derivatives
- indole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/44—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838332435A GB8332435D0 (en) | 1983-12-06 | 1983-12-06 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SG65790G true SG65790G (en) | 1990-10-26 |
Family
ID=10552845
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG65790A SG65790G (en) | 1983-12-06 | 1990-08-06 | Indole derivatives |
Country Status (27)
Country | Link |
---|---|
US (1) | US4994483A (fi) |
JP (2) | JPH062733B2 (fi) |
KR (1) | KR850004459A (fi) |
CN (2) | CN85104233A (fi) |
AT (1) | AT381934B (fi) |
AU (1) | AU575365B2 (fi) |
BE (1) | BE901224A (fi) |
CA (1) | CA1233183A (fi) |
CH (1) | CH663411A5 (fi) |
CY (1) | CY1562A (fi) |
DE (1) | DE3444572C2 (fi) |
DK (2) | DK583684A (fi) |
ES (2) | ES8607234A1 (fi) |
FI (1) | FI80260C (fi) |
FR (1) | FR2555987B1 (fi) |
GB (2) | GB8332435D0 (fi) |
HK (1) | HK85690A (fi) |
HU (2) | HU196752B (fi) |
IL (1) | IL73756A (fi) |
IT (1) | IT1178268B (fi) |
NL (1) | NL8403719A (fi) |
NO (1) | NO162764C (fi) |
NZ (1) | NZ210469A (fi) |
PT (1) | PT80572B (fi) |
SE (1) | SE458446B (fi) |
SG (1) | SG65790G (fi) |
ZA (1) | ZA849498B (fi) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8332437D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
GB8430624D0 (en) * | 1984-12-04 | 1985-01-09 | Glaxo Group Ltd | Chemical compounds |
IT1181741B (it) * | 1984-12-04 | 1987-09-30 | Glaxo Group Ltd | Derivati di indolo,procedimento per prepararli e composizioni farmaceutiche che li contengono |
GB8600397D0 (en) * | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
US5270333A (en) * | 1986-01-28 | 1993-12-14 | Glaxo Group Limited | Indole derivatives |
GB8601959D0 (en) * | 1986-01-28 | 1986-03-05 | Glaxo Group Ltd | Indole derivatives |
GB8719167D0 (en) * | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
DK172696B1 (da) * | 1987-08-13 | 1999-05-31 | Glaxo Group Ltd | Indolderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende forbindelserne |
US5225431A (en) * | 1987-10-23 | 1993-07-06 | Burroughs Wellcome Co. | Therapeutic substituted indole compounds and compositions thereof |
JPH01312506A (ja) * | 1988-06-13 | 1989-12-18 | Mitsui Petrochem Ind Ltd | カラーフィルター |
MC2210A1 (fr) * | 1990-06-07 | 1992-11-26 | Wellcome Found | Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer |
GB9209882D0 (en) * | 1992-05-07 | 1992-06-24 | Glaxo Lab Sa | Compositions |
GB9211277D0 (en) | 1992-05-28 | 1992-07-15 | Glaxo Group Inc | Pharmaceutical compositions |
ES2055651B1 (es) * | 1992-07-20 | 1995-03-01 | Vita Invest Sa | Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles. |
IT1264813B1 (it) * | 1993-07-28 | 1996-10-10 | Oxon Italia Spa | Procedimento per la preparazione di alcansolfonammidi |
EP0875513A1 (en) * | 1997-04-14 | 1998-11-04 | Eli Lilly And Company | Substituted heteroaromatic 5-HT 1F agonists |
US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
GB9926250D0 (en) * | 1999-11-06 | 2000-01-12 | Knoll Ag | Chemical process |
US20030198669A1 (en) * | 2001-07-05 | 2003-10-23 | R.T. Alamo Ventures I, Llc | Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine |
US6685951B2 (en) | 2001-07-05 | 2004-02-03 | R. T. Alamo Ventures I, Inc. | Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine |
US20030017175A1 (en) * | 2001-07-05 | 2003-01-23 | R.T. Alamo Ventures I, Inc. | Sublingual administration of dihydroergotamine for the treatment of migraine |
CA2508290C (en) * | 2002-12-20 | 2017-02-28 | Ciba Specialty Chemicals Holding Inc. | Synthesis of amines and intermediates for the synthesis thereof |
WO2004099141A1 (en) * | 2003-05-12 | 2004-11-18 | Ramesh Babu Potluri | A novel process for preparation of indole derivatives |
CA2569964A1 (en) * | 2004-06-10 | 2005-12-29 | Duramed Pharmaceuticals, Inc. | Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same |
JP5833804B2 (ja) * | 2005-04-13 | 2015-12-16 | ニューラクソン,インコーポレーテッド | Nos阻害活性を有する置換インドール化合物 |
CN101466709B (zh) * | 2006-04-13 | 2013-03-20 | 轴突公司 | 具有nos抑制活性的1,5和3,6-取代的吲哚化合物 |
WO2008056378A2 (en) * | 2006-11-09 | 2008-05-15 | Natco Pharma Limited | Novel process for the preparation of naratriptan hydrochloride |
PL2425820T3 (pl) | 2007-02-11 | 2015-08-31 | Map Pharmaceuticals Inc | Sposób terapeutycznego stosowania dhe w celu umożliwienia szybkiego złagodzenia migreny przy jednoczesnym zminimalizowaniu profilu działań niepożądanych |
WO2009064505A1 (en) * | 2007-11-16 | 2009-05-22 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods for treating visceral pain |
EP2220074A4 (en) * | 2007-11-16 | 2012-01-04 | Neuraxon Inc | 3,5-SUBSTITUTED INDOL COMPOUNDS WITH NOS AND NOREPINEPHRINE RECOVERY-HEMDERING EFFECT |
BRPI0820632A2 (pt) | 2007-11-16 | 2015-06-16 | Neuraxon Inc | Compostos de indol e métodos para tratamento de dor visceral |
US20110171141A1 (en) * | 2009-06-26 | 2011-07-14 | Kellerman Donald J | Administration of dihydroergotamine mesylate particles using a metered dose inhaler |
US11337962B2 (en) | 2009-09-25 | 2022-05-24 | Upsher-Smith Laboratories, Llc | Formulations comprising triptan compounds |
NZ599344A (en) | 2009-09-25 | 2015-02-27 | Reddy’S Lab Ltd Dr | Formulations comprising triptan compounds |
EP2716626A4 (en) * | 2011-05-27 | 2014-05-07 | Univ Tokushima | benzylamine |
ES2751388T3 (es) | 2011-07-22 | 2020-03-31 | Univ Chicago | IGF-1 para su uso en el tratamiento de la jaqueca |
CN102827062A (zh) * | 2012-09-17 | 2012-12-19 | 扬子江药业集团四川海蓉药业有限公司 | 苹果酸阿莫曲坦的制备方法 |
CA2895816C (en) | 2012-12-21 | 2021-02-23 | Map Pharmaceuticals, Inc. | 8'-hydroxy-dihydroergotamine compounds and compositions |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3322787A (en) * | 1964-09-25 | 1967-05-30 | Merck & Co Inc | Alpha-hydrazino-beta-(3-indolyl) alkanoic acid derivatives |
US3472870A (en) * | 1966-08-29 | 1969-10-14 | Mead Johnson & Co | Sulfonamidotryptamines |
US3468882A (en) * | 1966-10-07 | 1969-09-23 | Sterling Drug Inc | Phenylhydrazone derivatives as intermediates for preparing indoles |
IT1036004B (it) * | 1968-05-21 | 1979-10-30 | Abc Ist Biolog Chem Spa | Acidt 3 indolil adetoidrossamici |
US3730723A (en) * | 1971-06-17 | 1973-05-01 | Eastman Kodak Co | Direct positive processes utilizing silver halide surface image emulsions containing desensitizers |
US4283410A (en) * | 1978-06-15 | 1981-08-11 | Miles Laboratories, Inc. | 3-Amino or amido-2-(1H-indol-3-yl) propanoic acid derivatives |
ZA795239B (en) * | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
DE3131728A1 (de) * | 1980-08-12 | 1982-03-11 | Glaxo Group Ltd., London | Indolverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
ZW19381A1 (en) * | 1980-08-12 | 1983-03-09 | Glaxo Group Ltd | Heterocyclic compounds |
ES504694A0 (es) * | 1980-08-12 | 1982-11-01 | Glaxo Group Ltd | Procedimiento para la preparacion de derivados del indol. |
IT1170387B (it) * | 1982-06-07 | 1987-06-03 | Glaxo Group Ltd | Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono |
GB8332437D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
IT1181741B (it) * | 1984-12-04 | 1987-09-30 | Glaxo Group Ltd | Derivati di indolo,procedimento per prepararli e composizioni farmaceutiche che li contengono |
-
1983
- 1983-12-06 GB GB838332435A patent/GB8332435D0/en active Pending
- 1983-12-06 HU HU834168A patent/HU196752B/hu unknown
-
1984
- 1984-12-05 FI FI844789A patent/FI80260C/fi not_active IP Right Cessation
- 1984-12-06 CH CH5810/84A patent/CH663411A5/fr not_active IP Right Cessation
- 1984-12-06 JP JP59258409A patent/JPH062733B2/ja not_active Expired - Lifetime
- 1984-12-06 FR FR8418618A patent/FR2555987B1/fr not_active Expired
- 1984-12-06 ES ES538336A patent/ES8607234A1/es not_active Expired
- 1984-12-06 CA CA000469528A patent/CA1233183A/en not_active Expired
- 1984-12-06 SE SE8406200A patent/SE458446B/sv not_active IP Right Cessation
- 1984-12-06 NO NO84844879A patent/NO162764C/no unknown
- 1984-12-06 NZ NZ210469A patent/NZ210469A/xx unknown
- 1984-12-06 AT AT0387384A patent/AT381934B/de not_active IP Right Cessation
- 1984-12-06 KR KR1019840007709A patent/KR850004459A/ko not_active Application Discontinuation
- 1984-12-06 DK DK583684A patent/DK583684A/da not_active Application Discontinuation
- 1984-12-06 IT IT49265/84A patent/IT1178268B/it active
- 1984-12-06 IL IL73756A patent/IL73756A/xx unknown
- 1984-12-06 BE BE0/214125A patent/BE901224A/fr not_active IP Right Cessation
- 1984-12-06 NL NL8403719A patent/NL8403719A/nl not_active Application Discontinuation
- 1984-12-06 GB GB08430810A patent/GB2150932B/en not_active Expired
- 1984-12-06 AU AU36367/84A patent/AU575365B2/en not_active Ceased
- 1984-12-06 DE DE3444572A patent/DE3444572C2/de not_active Expired - Fee Related
- 1984-12-06 ZA ZA849498A patent/ZA849498B/xx unknown
-
1985
- 1985-05-30 HU HU852083A patent/HUT40624A/hu unknown
- 1985-05-31 PT PT80572A patent/PT80572B/pt not_active IP Right Cessation
- 1985-06-03 CN CN198585104233A patent/CN85104233A/zh active Pending
- 1985-08-19 CN CN85106225A patent/CN1015055B/zh not_active Expired
- 1985-09-02 ES ES546631A patent/ES8800150A1/es not_active Expired
-
1989
- 1989-11-30 US US07/443,874 patent/US4994483A/en not_active Expired - Fee Related
-
1990
- 1990-08-06 SG SG65790A patent/SG65790G/en unknown
- 1990-09-06 DK DK214090A patent/DK214090D0/da not_active Application Discontinuation
- 1990-10-18 HK HK856/90A patent/HK85690A/xx not_active IP Right Cessation
- 1990-11-29 JP JP2326200A patent/JPH03184958A/ja active Pending
-
1991
- 1991-05-17 CY CY1562A patent/CY1562A/xx unknown
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