SG166743A1 - Dye conjugates and methods of use - Google Patents

Dye conjugates and methods of use

Info

Publication number
SG166743A1
SG166743A1 SG201003378-5A SG2010033785A SG166743A1 SG 166743 A1 SG166743 A1 SG 166743A1 SG 2010033785 A SG2010033785 A SG 2010033785A SG 166743 A1 SG166743 A1 SG 166743A1
Authority
SG
Singapore
Prior art keywords
cyanines
disclosed
methods
articles
compositions
Prior art date
Application number
SG201003378-5A
Other languages
English (en)
Inventor
Ali Dehghani
Kamala Tyagarajan
Original Assignee
Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millipore Corp filed Critical Millipore Corp
Publication of SG166743A1 publication Critical patent/SG166743A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/06—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups three >CH- groups, e.g. carbocyanines
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/083—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines five >CH- groups
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/086—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines more than five >CH- groups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
SG201003378-5A 2009-05-15 2010-05-13 Dye conjugates and methods of use SG166743A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17887009P 2009-05-15 2009-05-15

Publications (1)

Publication Number Publication Date
SG166743A1 true SG166743A1 (en) 2010-12-29

Family

ID=42771999

Family Applications (1)

Application Number Title Priority Date Filing Date
SG201003378-5A SG166743A1 (en) 2009-05-15 2010-05-13 Dye conjugates and methods of use

Country Status (5)

Country Link
US (1) US20100291706A1 (https=)
EP (1) EP2251380A3 (https=)
JP (1) JP2010280888A (https=)
CN (1) CN101885761A (https=)
SG (1) SG166743A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012048063A2 (en) * 2010-10-06 2012-04-12 Emd Millipore Corporation Cyanine compounds, conjugates and method of use
EP2758475B1 (en) 2011-09-23 2017-04-26 Illumina Cambridge Limited Dyes for labelling molecular ligands
US8809551B1 (en) 2013-03-08 2014-08-19 Illumina Cambridge Limited Polymethine compounds and their use as fluorescent labels
GB201408077D0 (en) 2014-05-07 2014-06-18 Illumina Cambridge Ltd Polymethine compounds and their use as fluorescent labels
GB201508858D0 (en) 2015-05-22 2015-07-01 Illumina Cambridge Ltd Polymethine compounds with long stokes shifts and their use as fluorescent labels
KR102502117B1 (ko) * 2015-07-16 2023-02-22 에스에프씨 주식회사 염료 화합물
GB201516987D0 (en) 2015-09-25 2015-11-11 Illumina Cambridge Ltd Polymethine compounds and their use as fluorescent labels
CN115109435A (zh) * 2021-03-19 2022-09-27 湖北华大基因研究院 水溶性荧光染料偶联物的纯化方法

Family Cites Families (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55116259A (en) * 1979-03-01 1980-09-06 Fuji Photo Film Co Ltd Microimmunoassay method
DE3210596A1 (de) * 1982-03-23 1983-10-06 Bayer Ag Verfahren zur herstellung von kationischen methinfarbstoffen
DE3213966A1 (de) * 1982-04-16 1983-10-27 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von kationischen methinfarbstoffen
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4929524A (en) * 1986-09-12 1990-05-29 Canon Kabushiki Kaisha Organic photo conductive medium
JPS63208525A (ja) * 1987-02-25 1988-08-30 Kikkoman Corp 心不全治療剤
JPH0769583B2 (ja) * 1987-10-26 1995-07-31 富士写真フイルム株式会社 ハロゲン化銀写真感光材料
EP0367540A2 (en) * 1988-11-01 1990-05-09 Konica Corporation Silver halide photographic material
JPH02129628A (ja) * 1988-11-09 1990-05-17 Fuji Photo Film Co Ltd ハロゲン化銀カラー写真感光材料
JPH0778611B2 (ja) * 1988-11-15 1995-08-23 富士写真フイルム株式会社 ハロゲン化銀写真乳剤
JP2571115B2 (ja) * 1989-01-17 1997-01-16 富士写真フイルム株式会社 感光性組成物の増感方法及び増感された感光性組成物
JP2632052B2 (ja) * 1989-10-06 1997-07-16 富士写真フイルム株式会社 ハロゲン化銀写真感光材料
US5135845A (en) * 1990-04-10 1992-08-04 Eastman Kodak Company Sensitizing dye for photographic materials
DE69128809T2 (de) * 1990-04-16 1998-05-14 Fuji Photo Film Co Ltd Durch Erwärmung entwickelbares farbempfindliches Material
US5230995A (en) * 1990-04-26 1993-07-27 Fuji Photo Film Co., Ltd. Method of manufacturing silver halide emulsion and a color photographic material having the emulsion manufactured by the method
EP0786469B1 (en) 1990-06-11 2006-03-01 Gilead Sciences, Inc. Methods of use of nucleic acid ligands
GB2276169A (en) 1990-07-05 1994-09-21 Celltech Ltd Antibodies specific for carcinoembryonic antigen
EP0549692A4 (en) 1990-09-21 1993-08-25 Fred Hutchinson Cancer Research Center Protein sequence-specific oligonucleotide sequences
EP0491176A1 (en) * 1990-11-21 1992-06-24 Konica Corporation Silver halide photographic light-sensitive material improved in anti-jamming property
CA2104698A1 (en) 1991-02-21 1992-08-22 John J. Toole Aptamers specific for biomolecules and methods of making
DE69230387T2 (de) * 1991-04-22 2000-06-29 Fuji Photo Film Co., Ltd. Photographische Silberhalogenidmaterialien und Verfahren zu ihrer Verarbeitung
JP2663067B2 (ja) * 1991-07-17 1997-10-15 富士写真フイルム株式会社 直接ポジ用ハロゲン化銀感光材料の現像処理方法
JP2691095B2 (ja) * 1991-09-18 1997-12-17 富士写真フイルム株式会社 ハロゲン化銀写真感光材料
JP2987823B2 (ja) * 1991-09-19 1999-12-06 コニカ株式会社 ネガ型ハロゲン化銀乳剤の製造方法
JP2787630B2 (ja) * 1992-02-06 1998-08-20 富士写真フイルム株式会社 ハロゲン化銀感光材料
DE69325605T2 (de) * 1992-04-09 1999-11-04 Fuji Photo Film Co., Ltd. Photographisches lichtempfindliches Silberhalogenidmaterial
JPH06110149A (ja) * 1992-09-30 1994-04-22 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料
JP3354975B2 (ja) * 1992-10-06 2002-12-09 イビデン株式会社 蛍光標識試薬および蛍光免疫測定法
JPH06175289A (ja) * 1992-12-03 1994-06-24 Fuji Photo Film Co Ltd ハロゲン化銀カラー写真感光材料
JP3110915B2 (ja) * 1992-12-24 2000-11-20 富士写真フイルム株式会社 ハロゲン化銀写真感光材料およびそれを用いた画像形成方法
JPH06258759A (ja) * 1993-03-03 1994-09-16 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料
US5426015A (en) * 1993-10-18 1995-06-20 Eastman Kodak Company Metallized azo dianion with two cationic dye counter ions for optical information recording medium
KR100310223B1 (ko) * 1994-02-28 2001-12-28 윤종용 유기광기록매체및그의재기록방지방법
JPH07266705A (ja) * 1994-03-31 1995-10-17 Tdk Corp 光記録ディスク
DE4426892A1 (de) * 1994-07-29 1996-02-15 Riedel De Haen Ag Verwendung von Indolenincyanindisulfonsäure-Derivaten
DE69501861T2 (de) * 1994-08-17 1998-07-23 Fuji Photo Film Co Ltd Photographisches Silberhalogenidmaterial enthaltend einen pyrasolon-pentamethin oxonol Farbstoff
US5681702A (en) 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
US6008373A (en) * 1995-06-07 1999-12-28 Carnegie Mellon University Fluorescent labeling complexes with large stokes shift formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer
US5786123A (en) * 1996-03-19 1998-07-28 Eastman Kodak Company Optical recording elements comprising a polymeric dye
US5645910A (en) * 1995-06-19 1997-07-08 Eastman Kodak Company Formazan-cyanine copolymers dyes for optical recording layers and elements
JP3292007B2 (ja) * 1995-11-09 2002-06-17 松下電器産業株式会社 色素標識タンパク質複合体及びその作製方法
US5667860A (en) * 1995-11-14 1997-09-16 Eastman Kodak Company Optical recording elements having recording layers exhibiting reduced bubble formation
DE19605451A1 (de) * 1996-02-15 1997-08-21 Bayer Ag Elektrochromes System
DE19631728A1 (de) * 1996-08-06 1998-02-12 Bayer Ag Elektrochrome Anzeigevorrichtung
DE19631729A1 (de) * 1996-08-06 1998-02-12 Bayer Ag Elektrochromes System
JPH10123664A (ja) * 1996-10-15 1998-05-15 Fuji Photo Film Co Ltd 熱現像感光材料
US5876821A (en) * 1996-10-16 1999-03-02 Eastman Kodak Company Tetra dye mixed with another dye or dyes for optical recording elements
US6361922B1 (en) * 1996-10-16 2002-03-26 Eastman Kodak Company Thicker optical recording layers comprising a tetra dye having a metallized azo dianionic dye with cationic dye counterions
TW354785B (en) * 1996-12-12 1999-03-21 Ind Tech Res Inst Preparation of novel cyanine dyes for optical disk
DE19735733A1 (de) * 1997-08-18 1999-02-25 Bayer Ag Elektrochromes System mit gekoppeltem RED-OX-System und speziellen Anionen
DE19735732A1 (de) * 1997-08-18 1999-02-25 Bayer Ag UV-geschützte elektrochrome Lösung
JPH11208118A (ja) * 1997-11-20 1999-08-03 Taiyo Yuden Co Ltd 光情報記録媒体
US6251577B1 (en) * 1998-03-12 2001-06-26 Fuji Photo Film Co., Ltd. Method of manufacturing silver halide photographic emulsion, silver halide photographic emulsion manufactured by the method, and method of inhibiting aggregation of the emulsion
DE19834745A1 (de) * 1998-08-01 2000-02-03 Agfa Gevaert Ag Strahlungsempfindliches Gemisch mit IR-absorbierenden, anionischen Cyaninfarbstoffen und damit hergestelltes Aufzeichnungsmaterial
DE19906655A1 (de) * 1999-02-18 2000-11-16 Bayer Ag Elektrochrome Vorrichtung mit verbesserter Lichtechtheit
US6114350A (en) * 1999-04-19 2000-09-05 Nen Life Science Products, Inc. Cyanine dyes and synthesis methods thereof
JP3673963B2 (ja) * 1999-12-01 2005-07-20 太陽誘電株式会社 光情報記録媒体
US6716994B1 (en) * 2000-01-04 2004-04-06 Applera Corporation Mobility-Modifying Cyanine Dyes
TW460544B (en) * 2000-01-28 2001-10-21 Ind Tech Res Inst Preparation of cyanine dye for high density optical recording disk
US20020001784A1 (en) * 2000-03-23 2002-01-03 Masashi Shirata Silver halide photographic emulsion
US6506539B2 (en) * 2000-04-06 2003-01-14 Fuji Photo Film Co., Ltd. Dye complex and optical information recording medium
US20090081401A1 (en) * 2000-08-25 2009-03-26 Kabushiki Kaisha, Hayashibara, Seibutsu, Kagaku Kenky Optical recording media
US20020037474A1 (en) * 2000-09-20 2002-03-28 Wen-Yih Liao Memory Layer of high-density recordable optical recording
US6706468B2 (en) * 2000-09-28 2004-03-16 Fuji Photo Film Co., Ltd. Silver halide photographic emulsion and silver halide color photographic material using the same
US6727054B2 (en) * 2000-09-28 2004-04-27 Fuji Photo Film Co., Ltd. Silver halide photographic emulsion and silver halide color photographic material using the same
US6902878B1 (en) * 2000-09-28 2005-06-07 Fuji Photo Film Co., Ltd. Silver halide photographic emulsion and silver halide color photographic material using the same
US6607876B2 (en) * 2000-12-21 2003-08-19 Agfa-Gevaert Radiographic film material and intensifying screen-film combination
JP3517210B2 (ja) * 2000-12-28 2004-04-12 日清紡績株式会社 近赤外線吸収材料
JP2003020416A (ja) * 2001-07-06 2003-01-24 Fuji Photo Film Co Ltd テトラシアノキノジメタン化合物を対アニオンとした特定構造のシアニン色素化合物及び該シアニン色素化合物を含む光情報記録媒体
WO2003059929A1 (en) * 2001-12-21 2003-07-24 Applera Corporation Heteroconfigurational polynucleotide and methods of use
US8229548B2 (en) * 2002-03-12 2012-07-24 Beth Israel Deaconess Medical Center Medical imaging systems
US20040018458A1 (en) * 2002-05-17 2004-01-29 Hajime Nakagawa Photothermographic material
WO2004003510A2 (en) * 2002-07-01 2004-01-08 Guava Technologies, Inc. Fluorescent dyes, energy transfer couples and methods
US6716509B2 (en) * 2002-08-20 2004-04-06 Cmc Magnetics Corporation Optical recording medium
JP4085006B2 (ja) * 2003-01-14 2008-04-30 富士フイルム株式会社 平版印刷版用原版
US7087359B2 (en) * 2003-01-27 2006-08-08 Agfa-Gevaert Heat-sensitive lithographic printing plate precursor
US7172907B2 (en) * 2003-03-21 2007-02-06 Ge Healthcare Bio-Sciences Corp. Cyanine dye labelling reagents with meso-substitution
US7736631B2 (en) * 2003-04-01 2010-06-15 L'oreal S.A. Cosmetic dye composition with a lightening effect for human keratin materials, comprising at least one fluorescent dye and at least one aminosilicone, and process of dyeing
GB0317123D0 (en) * 2003-07-22 2003-08-27 Xzillion Gmbh & Co Kg Characterising polypeptides
JP2005049608A (ja) * 2003-07-29 2005-02-24 Fuji Photo Film Co Ltd 体積型ホログラム記録用感光性組成物及びそれを用いた体積型ホログラム記録媒体
JP4943156B2 (ja) * 2003-10-31 2012-05-30 ジーイー・ヘルスケア・ユーケイ・リミテッド シアニン色素標識用試薬
WO2005067383A2 (en) * 2004-01-13 2005-07-28 Spectrum Dynamics Llc Multi-dimensional image reconstruction
US8571881B2 (en) * 2004-11-09 2013-10-29 Spectrum Dynamics, Llc Radiopharmaceutical dispensing, administration, and imaging
WO2007054935A2 (en) * 2005-11-09 2007-05-18 Spectrum Dynamics Llc Dynamic spect camera
DE102004005657A1 (de) * 2004-02-04 2005-08-25 Basf Ag Fließfähige Polyesterformmassen
JP5280683B2 (ja) * 2004-06-16 2013-09-04 ジーイー・ヘルスケア・アクスイェ・セルスカプ ペプチド系化合物
US20060162098A1 (en) * 2004-06-23 2006-07-27 Alain Lagrange Use of polycationic compounds for dyeing keratin fibres
JP4725516B2 (ja) * 2004-06-25 2011-07-13 旭硝子株式会社 重合性液晶化合物、液晶組成物、および光学異方性材料
US7532326B2 (en) * 2004-07-07 2009-05-12 Corcoran Timothy C Multiple-label fluorescence imaging using excitation-emission matrices
KR101318713B1 (ko) * 2004-08-27 2013-10-16 각고호우징 게이오기주크 세포내 미토콘드리아를 지표로 이용하는 심근 세포의 선별방법
JP4436737B2 (ja) * 2004-09-10 2010-03-24 富士フイルム株式会社 ２光子吸収消色材料、２光子吸収屈折率変調材料、２光子吸収重合材料、２光子吸収重合方法、及び３次元光記録材料
WO2006123807A1 (ja) * 2005-05-17 2006-11-23 Mitsui Chemicals, Inc. トリメチン二量体化合物及びこれを用いた光記録媒体
JP5004506B2 (ja) * 2005-06-24 2012-08-22 株式会社Ａｄｅｋａ 光学フィルター
KR100705927B1 (ko) * 2005-10-26 2007-04-12 제일모직주식회사 근적외선 흡수 및 색보정 점착제 조성물 및 이를 이용한필름
WO2007100392A2 (en) * 2005-11-30 2007-09-07 Biotium, Inc. Enzyme substrate comprising a functional dye and associated technology and methods
DE102006029454A1 (de) * 2005-12-05 2007-06-06 Dyomics Gmbh Hydrophile Marker auf Basis von diasteromeren
US7402813B2 (en) * 2005-12-13 2008-07-22 Spectrum Dynamics Llc Lens system for nuclear medicine gamma ray camera
FR2895904B1 (fr) * 2006-01-12 2008-02-29 Oreal Utilisation pour la coloration avec effet eclaircissant des matieres keratiniques d'une composition comprenant un colorant fluorescent de type cyanine
JP4982695B2 (ja) * 2006-03-16 2012-07-25 株式会社リコー 光記録媒体
TW200815537A (en) * 2006-09-22 2008-04-01 Sumitomo Seika Chemicals Light-absorbing pigment composition
US20080096193A1 (en) * 2006-10-24 2008-04-24 Charles Robert Bupp Methods and compositions for detecting polynucleotides
WO2008067445A2 (en) * 2006-11-29 2008-06-05 Sun Chemical Corporation Poly(oxyalkylene)ated colorants and their use as fluorescent security taggants
GB0624462D0 (en) * 2006-12-07 2007-01-17 Ge Healthcare Ltd Method for determining gentoxicity
KR20100017102A (ko) * 2007-05-16 2010-02-16 지이 헬스케어 에이에스 광학 조영제
WO2010117420A2 (en) * 2009-03-30 2010-10-14 Pacific Biosciences Of California, Inc. Fret-labeled compounds and uses therefor

Also Published As

Publication number Publication date
EP2251380A2 (en) 2010-11-17
EP2251380A3 (en) 2011-01-05
CN101885761A (zh) 2010-11-17
US20100291706A1 (en) 2010-11-18
JP2010280888A (ja) 2010-12-16

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