SG148823A1 - Pharmaceutical compositions of fibrinolytic agent - Google Patents

Pharmaceutical compositions of fibrinolytic agent

Info

Publication number
SG148823A1
SG148823A1 SG200400542-7A SG2004005427A SG148823A1 SG 148823 A1 SG148823 A1 SG 148823A1 SG 2004005427 A SG2004005427 A SG 2004005427A SG 148823 A1 SG148823 A1 SG 148823A1
Authority
SG
Singapore
Prior art keywords
fibrinolytic agent
pharmaceutical compositions
lyophilized
compositions
lyophilized composition
Prior art date
Application number
SG200400542-7A
Other languages
English (en)
Inventor
Brent S Kendrick
Brian Peterson
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SG148823A1 publication Critical patent/SG148823A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG200400542-7A 1999-10-01 2000-09-29 Pharmaceutical compositions of fibrinolytic agent SG148823A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/411,335 US6440414B1 (en) 1999-10-01 1999-10-01 Pharmaceutical compositions of fibrinolytic agent

Publications (1)

Publication Number Publication Date
SG148823A1 true SG148823A1 (en) 2009-01-29

Family

ID=23628514

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200400542-7A SG148823A1 (en) 1999-10-01 2000-09-29 Pharmaceutical compositions of fibrinolytic agent

Country Status (28)

Country Link
US (4) US6440414B1 (bg)
EP (2) EP1438967A3 (bg)
JP (1) JP2003510369A (bg)
KR (1) KR100717435B1 (bg)
CN (2) CN101209347A (bg)
AT (1) ATE262923T1 (bg)
AU (1) AU769313B2 (bg)
BG (1) BG106578A (bg)
BR (1) BR0014420A (bg)
CA (1) CA2385966A1 (bg)
CZ (1) CZ20021033A3 (bg)
DE (2) DE04007657T1 (bg)
DK (1) DK1220685T3 (bg)
EA (2) EA006600B1 (bg)
ES (2) ES2218228T3 (bg)
HK (1) HK1049112B (bg)
HU (1) HUP0202654A3 (bg)
IL (1) IL148842A0 (bg)
MX (1) MXPA02003197A (bg)
NO (1) NO20021500L (bg)
NZ (4) NZ540967A (bg)
PL (1) PL355016A1 (bg)
PT (1) PT1220685E (bg)
SG (1) SG148823A1 (bg)
SK (1) SK4242002A3 (bg)
WO (1) WO2001024817A2 (bg)
YU (1) YU23302A (bg)
ZA (1) ZA200202400B (bg)

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RU2244556C2 (ru) 1999-02-22 2005-01-20 Юниверсити Оф Коннектикут Новые не содержащие альбумин составы фактора viii
US6440414B1 (en) 1999-10-01 2002-08-27 Amgen Inc. Pharmaceutical compositions of fibrinolytic agent
US6261820B1 (en) 1999-10-01 2001-07-17 Amgen Inc. Fibronolytically active polypeptide
US7033776B2 (en) 1999-12-17 2006-04-25 Amgen Inc. Method for treatment of indwelling catheter occlusion using fibrinolytic metalloproteinases
US6455269B1 (en) 1999-12-17 2002-09-24 Amgen, Inc. Method for localized administration of fibrinolytic metalloproteinases
DE10149030A1 (de) * 2001-10-05 2003-04-10 Viscum Ag Stabile galenische gefriergetrocknete Arzneimittelzubereitung von rViscumin
ATE326985T1 (de) * 2002-02-01 2006-06-15 Shimoda Biotech Pty Ltd Lyophilisierte pharmazeutische zusammensetzung von propofol
CA2472956A1 (en) * 2002-02-14 2003-08-21 Bayer Pharmaceuticals Corporation Formulation strategies in stabilizing peptides in organic solvents and in dried states
US6803046B2 (en) * 2002-08-16 2004-10-12 Bracco International B.V. Sincalide formulations
CN101084008B (zh) * 2004-12-15 2013-04-10 比奥维特罗姆股份公开公司 角质形成细胞生长因子的治疗制剂
CA2628047A1 (en) * 2005-11-18 2007-05-24 Eisai R & D Management Co., Ltd. Process for production of cinnamide derivative
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
WO2008056840A1 (en) * 2006-11-08 2008-05-15 Silla University Industry Academic Cooperation Foundation Fibrinolytic metalloprotease and composition comprising the same
EP1958618A1 (de) 2007-02-15 2008-08-20 Octapharma AG Verfahren zur Gefriertrocknung mit optimierter Rekonstitution von Biopolymeren
JP5779780B2 (ja) 2008-11-07 2015-09-16 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 第viii因子製剤
JP5819293B2 (ja) 2009-07-10 2015-11-24 スロンボジェニックス・ナムローゼ・フェンノートシャップThromboGenics NV プラスミノーゲンおよびプラスミンの変異体
CN102000022A (zh) * 2010-11-23 2011-04-06 郑州大学 注射用重组双功能纤溶酶冻干制剂及其制备方法
WO2012093132A1 (en) 2011-01-05 2012-07-12 Thrombogenics Nv Plasminogen and plasmin variants
AU2012296884B2 (en) 2011-08-12 2015-02-05 Thrombogenics N.V. Plasminogen and plasmin variants
US20140212405A1 (en) 2013-01-28 2014-07-31 2294719 Ontario Limited Fibrinolytic/Proteolytic Treatment of Myofacial and Neuropathic Pain and Related Conditions
WO2016073668A1 (en) * 2014-11-06 2016-05-12 The Regents Of The University Of Colorado Identification of novel disease states using viscoelastic analysis in the presence of a thrombolytic agent
EP3906014A1 (en) * 2019-01-06 2021-11-10 Endo Global Aesthetics Limited Collagenase formulations and methods of producing the same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0323722A1 (en) * 1987-12-18 1989-07-12 Chiron Corporation Compositions and method for recombinant production of crotalidus venom fibrolase
EP0689843A1 (en) * 1993-12-17 1996-01-03 Mochida Pharmaceutical Co., Ltd. Composition containing soluble thrombomodulins

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AU7293381A (en) * 1980-06-27 1982-02-02 Movement Techniques Ltd. Movement measuring apparatus and landmarks for use therewith
US4447236A (en) * 1982-02-05 1984-05-08 Cordis Corporation Infusion catheter system
US4610879A (en) 1984-01-06 1986-09-09 University Of Southern California Fibrinolytic enzyme from snake vernom
CA1237482A (en) * 1984-03-09 1988-05-31 Frank B. Stiles Catheter for effecting removal of obstructions from a biological duct
US4755167A (en) * 1984-04-10 1988-07-05 Research Corporation In vivo method for distribution and stirring of therapeutic agents
US4885242A (en) * 1984-10-30 1989-12-05 Phillips Petroleum Company Genes from pichia histidine pathway and uses thereof
US4837148A (en) * 1984-10-30 1989-06-06 Phillips Petroleum Company Autonomous replication sequences for yeast strains of the genus pichia
US4855231A (en) * 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
US4818700A (en) * 1985-10-25 1989-04-04 Phillips Petroleum Company Pichia pastoris argininosuccinate lyase gene and uses thereof
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US5000185A (en) * 1986-02-28 1991-03-19 Cardiovascular Imaging Systems, Inc. Method for intravascular two-dimensional ultrasonography and recanalization
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ATE220721T1 (de) 1990-01-16 2002-08-15 Ct Ingenieria Genetica Biotech Verfahren zur expression heterologischer gene in der hefe pichia pastoris, expressionsvektoren und transformierte mikroorganismen
US5709676A (en) * 1990-02-14 1998-01-20 Alt; Eckhard Synergistic treatment of stenosed blood vessels using shock waves and dissolving medication
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US5951981A (en) 1996-12-02 1999-09-14 Diatide, Inc. Thrombolytic agents with antithrombotic activity
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US6261820B1 (en) 1999-10-01 2001-07-17 Amgen Inc. Fibronolytically active polypeptide
US6440414B1 (en) 1999-10-01 2002-08-27 Amgen Inc. Pharmaceutical compositions of fibrinolytic agent
US6455269B1 (en) * 1999-12-17 2002-09-24 Amgen, Inc. Method for localized administration of fibrinolytic metalloproteinases
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Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
EP0323722A1 (en) * 1987-12-18 1989-07-12 Chiron Corporation Compositions and method for recombinant production of crotalidus venom fibrolase
EP0689843A1 (en) * 1993-12-17 1996-01-03 Mochida Pharmaceutical Co., Ltd. Composition containing soluble thrombomodulins

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* Cited by examiner, † Cited by third party
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STABILIZATION VS. DEGRADATION OF STAPHYLOCOCCUS AUREUS METALLOPROTEINASE *

Also Published As

Publication number Publication date
NO20021500D0 (no) 2002-03-26
WO2001024817A3 (en) 2001-10-18
YU23302A (sh) 2005-06-10
WO2001024817A2 (en) 2001-04-12
ZA200202400B (en) 2003-05-28
CN1402641A (zh) 2003-03-12
ES2224917T1 (es) 2005-03-16
PT1220685E (pt) 2004-08-31
DE04007657T1 (de) 2005-01-13
DE60009529D1 (de) 2004-05-06
US20060263347A1 (en) 2006-11-23
EP1438967A3 (en) 2005-01-26
EA200200396A1 (ru) 2002-10-31
KR100717435B1 (ko) 2007-05-14
PL355016A1 (en) 2004-03-22
HUP0202654A3 (en) 2003-11-28
EP1438967A2 (en) 2004-07-21
MXPA02003197A (es) 2002-09-30
DE60009529T2 (de) 2005-04-14
CZ20021033A3 (cs) 2003-06-18
AU769313B2 (en) 2004-01-22
KR20020053065A (ko) 2002-07-04
US6440414B1 (en) 2002-08-27
EP1220685A2 (en) 2002-07-10
SK4242002A3 (en) 2003-08-05
JP2003510369A (ja) 2003-03-18
BR0014420A (pt) 2002-06-11
NZ530959A (en) 2005-08-26
IL148842A0 (en) 2002-09-12
HK1049112B (zh) 2005-01-21
NO20021500L (no) 2002-05-27
EA006600B1 (ru) 2006-02-24
EA200400182A1 (ru) 2004-08-26
EA004627B1 (ru) 2004-06-24
ES2218228T3 (es) 2004-11-16
NZ540967A (en) 2007-02-23
CN100353999C (zh) 2007-12-12
AU7743000A (en) 2001-05-10
US7311908B2 (en) 2007-12-25
BG106578A (bg) 2003-04-30
ATE262923T1 (de) 2004-04-15
HK1049112A1 (en) 2003-05-02
US20060246053A1 (en) 2006-11-02
NZ550200A (en) 2008-04-30
US20020192207A1 (en) 2002-12-19
EP1220685B1 (en) 2004-03-31
US7244426B2 (en) 2007-07-17
CN101209347A (zh) 2008-07-02
CA2385966A1 (en) 2001-04-12
DK1220685T3 (da) 2004-08-02
NZ518007A (en) 2004-03-26
US7138114B2 (en) 2006-11-21
HUP0202654A2 (hu) 2002-12-28

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