PT1220685E - Composicoes farmaceuticas de um agente fibrinolitico - Google Patents

Composicoes farmaceuticas de um agente fibrinolitico

Info

Publication number
PT1220685E
PT1220685E PT00967197T PT00967197T PT1220685E PT 1220685 E PT1220685 E PT 1220685E PT 00967197 T PT00967197 T PT 00967197T PT 00967197 T PT00967197 T PT 00967197T PT 1220685 E PT1220685 E PT 1220685E
Authority
PT
Portugal
Prior art keywords
agent
fibrinolitic
pharmaceutical compositions
lyophilized
lyophilized composition
Prior art date
Application number
PT00967197T
Other languages
English (en)
Inventor
Brent S Kendrick
Brian Peterson
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of PT1220685E publication Critical patent/PT1220685E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
PT00967197T 1999-10-01 2000-09-29 Composicoes farmaceuticas de um agente fibrinolitico PT1220685E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/411,335 US6440414B1 (en) 1999-10-01 1999-10-01 Pharmaceutical compositions of fibrinolytic agent

Publications (1)

Publication Number Publication Date
PT1220685E true PT1220685E (pt) 2004-08-31

Family

ID=23628514

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00967197T PT1220685E (pt) 1999-10-01 2000-09-29 Composicoes farmaceuticas de um agente fibrinolitico

Country Status (28)

Country Link
US (4) US6440414B1 (pt)
EP (2) EP1438967A3 (pt)
JP (1) JP2003510369A (pt)
KR (1) KR100717435B1 (pt)
CN (2) CN101209347A (pt)
AT (1) ATE262923T1 (pt)
AU (1) AU769313B2 (pt)
BG (1) BG106578A (pt)
BR (1) BR0014420A (pt)
CA (1) CA2385966A1 (pt)
CZ (1) CZ20021033A3 (pt)
DE (2) DE04007657T1 (pt)
DK (1) DK1220685T3 (pt)
EA (2) EA006600B1 (pt)
ES (2) ES2218228T3 (pt)
HK (1) HK1049112B (pt)
HU (1) HUP0202654A3 (pt)
IL (1) IL148842A0 (pt)
MX (1) MXPA02003197A (pt)
NO (1) NO20021500L (pt)
NZ (4) NZ540967A (pt)
PL (1) PL355016A1 (pt)
PT (1) PT1220685E (pt)
SG (1) SG148823A1 (pt)
SK (1) SK4242002A3 (pt)
WO (1) WO2001024817A2 (pt)
YU (1) YU23302A (pt)
ZA (1) ZA200202400B (pt)

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PT2130554E (pt) 1999-02-22 2012-11-19 Univ Connecticut Formulações de factor viii isentas de albumina
US6261820B1 (en) 1999-10-01 2001-07-17 Amgen Inc. Fibronolytically active polypeptide
US6440414B1 (en) 1999-10-01 2002-08-27 Amgen Inc. Pharmaceutical compositions of fibrinolytic agent
US6455269B1 (en) * 1999-12-17 2002-09-24 Amgen, Inc. Method for localized administration of fibrinolytic metalloproteinases
US7033776B2 (en) 1999-12-17 2006-04-25 Amgen Inc. Method for treatment of indwelling catheter occlusion using fibrinolytic metalloproteinases
DE10149030A1 (de) * 2001-10-05 2003-04-10 Viscum Ag Stabile galenische gefriergetrocknete Arzneimittelzubereitung von rViscumin
ATE326985T1 (de) * 2002-02-01 2006-06-15 Shimoda Biotech Pty Ltd Lyophilisierte pharmazeutische zusammensetzung von propofol
EP1476178A4 (en) * 2002-02-14 2009-08-26 Bayer Pharmaceuticals Corp FORMULATION STRATEGIES IN STABILIZING PEPTIDES IN ORGANIC SOLVENTS AND DRY CONDITIONS
US6803046B2 (en) * 2002-08-16 2004-10-12 Bracco International B.V. Sincalide formulations
PT1827483E (pt) * 2004-12-15 2014-09-25 Swedish Orphan Biovitrum Ab Publ Formulações terapêuticas do fator de crescimento de queratinócitos
WO2007058305A1 (ja) * 2005-11-18 2007-05-24 Eisai R & D Management Co., Ltd. シンナミド誘導体の製造方法
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
WO2008056840A1 (en) * 2006-11-08 2008-05-15 Silla University Industry Academic Cooperation Foundation Fibrinolytic metalloprotease and composition comprising the same
EP1958618A1 (de) 2007-02-15 2008-08-20 Octapharma AG Verfahren zur Gefriertrocknung mit optimierter Rekonstitution von Biopolymeren
US20100168018A1 (en) * 2008-11-07 2010-07-01 Baxter International Inc. Factor viii formulations
RU2564131C2 (ru) * 2009-07-10 2015-09-27 ТромбоДженикс НВ Варианты плазминогена и плазмина
CN102000022A (zh) * 2010-11-23 2011-04-06 郑州大学 注射用重组双功能纤溶酶冻干制剂及其制备方法
BR112013017172A2 (pt) 2011-01-05 2016-10-11 Thrombogenics Nv variantes de plasminogênio e plasmina
WO2013024074A1 (en) 2011-08-12 2013-02-21 Thrombogenics N.V. Plasminogen and plasmin variants
US20140212405A1 (en) 2013-01-28 2014-07-31 2294719 Ontario Limited Fibrinolytic/Proteolytic Treatment of Myofacial and Neuropathic Pain and Related Conditions
EP3215634B1 (en) * 2014-11-06 2021-08-04 The Regents of the University of Colorado Identification of novel disease states using viscoelastic analysis in the presence of a thrombolytic agent
BR112021012675A2 (pt) * 2019-01-06 2021-09-28 Endo Global Aesthetics Limited Formulação, formulação liofilizada, formulação reconstituída e kit

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CA1237482A (en) * 1984-03-09 1988-05-31 Frank B. Stiles Catheter for effecting removal of obstructions from a biological duct
US4755167A (en) * 1984-04-10 1988-07-05 Research Corporation In vivo method for distribution and stirring of therapeutic agents
US4855231A (en) * 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
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US5951981A (en) * 1996-12-02 1999-09-14 Diatide, Inc. Thrombolytic agents with antithrombotic activity
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US6440414B1 (en) 1999-10-01 2002-08-27 Amgen Inc. Pharmaceutical compositions of fibrinolytic agent
US6261820B1 (en) 1999-10-01 2001-07-17 Amgen Inc. Fibronolytically active polypeptide
US6455269B1 (en) * 1999-12-17 2002-09-24 Amgen, Inc. Method for localized administration of fibrinolytic metalloproteinases
WO2002012283A2 (en) 2000-08-03 2002-02-14 Zymogenetics, Inc. Disintegrin homologs, zsnk10, zsnk11, and zsnk12

Also Published As

Publication number Publication date
CN101209347A (zh) 2008-07-02
NZ550200A (en) 2008-04-30
EP1438967A2 (en) 2004-07-21
SG148823A1 (en) 2009-01-29
NZ518007A (en) 2004-03-26
EA200200396A1 (ru) 2002-10-31
DE04007657T1 (de) 2005-01-13
DE60009529D1 (de) 2004-05-06
US7138114B2 (en) 2006-11-21
DK1220685T3 (da) 2004-08-02
US20060263347A1 (en) 2006-11-23
AU7743000A (en) 2001-05-10
ES2224917T1 (es) 2005-03-16
ATE262923T1 (de) 2004-04-15
YU23302A (sh) 2005-06-10
SK4242002A3 (en) 2003-08-05
EP1438967A3 (en) 2005-01-26
MXPA02003197A (es) 2002-09-30
WO2001024817A2 (en) 2001-04-12
WO2001024817A3 (en) 2001-10-18
KR20020053065A (ko) 2002-07-04
HK1049112B (zh) 2005-01-21
US6440414B1 (en) 2002-08-27
IL148842A0 (en) 2002-09-12
CA2385966A1 (en) 2001-04-12
DE60009529T2 (de) 2005-04-14
EA200400182A1 (ru) 2004-08-26
HUP0202654A2 (hu) 2002-12-28
CN100353999C (zh) 2007-12-12
PL355016A1 (en) 2004-03-22
US20060246053A1 (en) 2006-11-02
NO20021500L (no) 2002-05-27
AU769313B2 (en) 2004-01-22
BR0014420A (pt) 2002-06-11
BG106578A (bg) 2003-04-30
CN1402641A (zh) 2003-03-12
HUP0202654A3 (en) 2003-11-28
US20020192207A1 (en) 2002-12-19
ZA200202400B (en) 2003-05-28
JP2003510369A (ja) 2003-03-18
ES2218228T3 (es) 2004-11-16
EP1220685A2 (en) 2002-07-10
US7311908B2 (en) 2007-12-25
NZ530959A (en) 2005-08-26
CZ20021033A3 (cs) 2003-06-18
US7244426B2 (en) 2007-07-17
NZ540967A (en) 2007-02-23
HK1049112A1 (en) 2003-05-02
EA004627B1 (ru) 2004-06-24
EA006600B1 (ru) 2006-02-24
EP1220685B1 (en) 2004-03-31
KR100717435B1 (ko) 2007-05-14
NO20021500D0 (no) 2002-03-26

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