PT1066304E - Antagonistas macrolidos de lhrh - Google Patents

Antagonistas macrolidos de lhrh

Info

Publication number
PT1066304E
PT1066304E PT99912259T PT99912259T PT1066304E PT 1066304 E PT1066304 E PT 1066304E PT 99912259 T PT99912259 T PT 99912259T PT 99912259 T PT99912259 T PT 99912259T PT 1066304 E PT1066304 E PT 1066304E
Authority
PT
Portugal
Prior art keywords
lhrh
antagonists
macrolid
compounds
disclosed
Prior art date
Application number
PT99912259T
Other languages
English (en)
Inventor
Christopher R Dalton
Daryl R Sauer
Haviv Fortuna
Randolph John
Nicholas A Mort
Bruncko Milan
Michele A Kaminski
Bradley W Crawford
Frey Lisa Marie
Greer Jonathon
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of PT1066304E publication Critical patent/PT1066304E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT99912259T 1998-03-27 1999-03-11 Antagonistas macrolidos de lhrh PT1066304E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/049,963 US5955440A (en) 1998-03-27 1998-03-27 Macrolide LHRH antagonists

Publications (1)

Publication Number Publication Date
PT1066304E true PT1066304E (pt) 2005-06-30

Family

ID=21962689

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99912259T PT1066304E (pt) 1998-03-27 1999-03-11 Antagonistas macrolidos de lhrh

Country Status (21)

Country Link
US (1) US5955440A (pt)
EP (1) EP1066304B1 (pt)
JP (1) JP2002509937A (pt)
KR (1) KR20010034694A (pt)
CN (1) CN1307584A (pt)
AT (1) ATE289609T1 (pt)
AU (1) AU3067499A (pt)
BG (1) BG104844A (pt)
BR (1) BR9909080A (pt)
CA (1) CA2325521A1 (pt)
DE (1) DE69923835T2 (pt)
ES (1) ES2238828T3 (pt)
HK (1) HK1036284A1 (pt)
HU (1) HUP0102011A3 (pt)
IL (1) IL138219A0 (pt)
NO (1) NO20004860L (pt)
PL (1) PL348242A1 (pt)
PT (1) PT1066304E (pt)
SK (1) SK13972000A3 (pt)
TR (1) TR200002767T2 (pt)
WO (1) WO1999050275A2 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387885B1 (en) * 1998-08-26 2002-05-14 Abbott Laboratories 3′,3′-N-bis-desmethyl-3′-N-cycloalkyl erythromycin derivatives as LHRH antagonists
DE60138876D1 (de) * 2000-03-28 2009-07-16 Sandoz Ag Geschmackmaskierte granulierte teilchen
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
TW200420573A (en) * 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
CN1780846A (zh) * 2003-03-05 2006-05-31 Rib－X医药品有限公司 双官能杂环化合物及其制备和使用方法
WO2005042554A1 (en) * 2003-10-30 2005-05-12 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same
JP2007512256A (ja) * 2003-11-18 2007-05-17 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法
US8202843B2 (en) 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
EP2233493A1 (en) * 2004-12-21 2010-09-29 Pfizer Products Inc. Macrolides
US8865662B2 (en) * 2009-08-13 2014-10-21 Basilea Pharmaceutica Ag Macrolides and their use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6187625A (ja) * 1984-10-05 1986-05-06 Satoshi Omura 消化管収縮運動促進剤
EP0215355B1 (en) * 1985-08-31 1994-04-06 Kitasato Kenkyusho Erythromycin derivative and process for preparing the same
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
DE69127457T2 (de) * 1990-11-28 1998-01-22 Taisho Pharmaceutical Co., Ltd., Tokio/Tokyo 6-0-methylerythromycin a-derivat
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
PL327146A1 (en) * 1995-12-14 1998-11-23 Merck & Co Inc Antagonists of the gonadotrophin liberating hormone
CZ351898A3 (cs) * 1996-05-07 1999-04-14 Abbott Laboratories 6-0-substituované erythromycinové sloučeniny a způsob jejich přípravy

Also Published As

Publication number Publication date
WO1999050275A3 (en) 2001-02-22
US5955440A (en) 1999-09-21
BG104844A (en) 2001-07-31
DE69923835T2 (de) 2006-04-06
TR200002767T2 (tr) 2001-05-21
KR20010034694A (ko) 2001-04-25
IL138219A0 (en) 2001-10-31
JP2002509937A (ja) 2002-04-02
ATE289609T1 (de) 2005-03-15
BR9909080A (pt) 2000-12-12
AU3067499A (en) 1999-10-18
EP1066304A1 (en) 2001-01-10
HK1036284A1 (en) 2001-12-28
HUP0102011A2 (hu) 2001-11-28
SK13972000A3 (sk) 2001-07-10
WO1999050275A2 (en) 1999-10-07
DE69923835D1 (de) 2005-03-31
PL348242A1 (en) 2002-05-20
CN1307584A (zh) 2001-08-08
CA2325521A1 (en) 1999-10-07
NO20004860D0 (no) 2000-09-27
ES2238828T3 (es) 2005-09-01
EP1066304B1 (en) 2005-02-23
NO20004860L (no) 2000-11-24
HUP0102011A3 (en) 2003-07-28

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