HK1036284A1 - Macrolide lhrh antagonists. - Google Patents

Macrolide lhrh antagonists.

Info

Publication number
HK1036284A1
HK1036284A1 HK01104717A HK01104717A HK1036284A1 HK 1036284 A1 HK1036284 A1 HK 1036284A1 HK 01104717 A HK01104717 A HK 01104717A HK 01104717 A HK01104717 A HK 01104717A HK 1036284 A1 HK1036284 A1 HK 1036284A1
Authority
HK
Hong Kong
Prior art keywords
lhrh antagonists
macrolide
compounds
disclosed
antagonists
Prior art date
Application number
HK01104717A
Other languages
English (en)
Inventor
Daryl R Sauer
Fortuna Haviv
John Randolph
Nicholas A Mort
Christopher R Dalton
Milan Bruncko
Michele A Kaminski
Bradley W Crawford
Lisa Marie Frey
Jonathon Greer
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of HK1036284A1 publication Critical patent/HK1036284A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK01104717A 1998-03-27 2001-07-09 Macrolide lhrh antagonists. HK1036284A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/049,963 US5955440A (en) 1998-03-27 1998-03-27 Macrolide LHRH antagonists
PCT/US1999/004658 WO1999050275A2 (en) 1998-03-27 1999-03-11 Macrolide lhrh antagonists

Publications (1)

Publication Number Publication Date
HK1036284A1 true HK1036284A1 (en) 2001-12-28

Family

ID=21962689

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01104717A HK1036284A1 (en) 1998-03-27 2001-07-09 Macrolide lhrh antagonists.

Country Status (21)

Country Link
US (1) US5955440A (xx)
EP (1) EP1066304B1 (xx)
JP (1) JP2002509937A (xx)
KR (1) KR20010034694A (xx)
CN (1) CN1307584A (xx)
AT (1) ATE289609T1 (xx)
AU (1) AU3067499A (xx)
BG (1) BG104844A (xx)
BR (1) BR9909080A (xx)
CA (1) CA2325521A1 (xx)
DE (1) DE69923835T2 (xx)
ES (1) ES2238828T3 (xx)
HK (1) HK1036284A1 (xx)
HU (1) HUP0102011A3 (xx)
IL (1) IL138219A0 (xx)
NO (1) NO20004860L (xx)
PL (1) PL348242A1 (xx)
PT (1) PT1066304E (xx)
SK (1) SK13972000A3 (xx)
TR (1) TR200002767T2 (xx)
WO (1) WO1999050275A2 (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387885B1 (en) * 1998-08-26 2002-05-14 Abbott Laboratories 3′,3′-N-bis-desmethyl-3′-N-cycloalkyl erythromycin derivatives as LHRH antagonists
KR20030011797A (ko) * 2000-03-28 2003-02-11 바이오케미 게젤샤프트 엠베하 맛이 차폐된 과립형 입자
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
TW200420573A (en) * 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
JP2006523229A (ja) * 2003-03-05 2006-10-12 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性複素環式化合物ならびにその製造および使用方法
EP1682563A1 (en) * 2003-10-30 2006-07-26 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and mehtods of making and using the same
JP2007512256A (ja) * 2003-11-18 2007-05-17 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法
JP5383037B2 (ja) * 2004-02-27 2014-01-08 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 大環状化合物およびそれらを製造し使用する方法
EP1836211B1 (en) * 2004-12-21 2010-03-03 Pfizer Products Inc. Macrolides
EP2464651B1 (en) * 2009-08-13 2016-04-20 Basilea Pharmaceutica AG New macrolides and their use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6187625A (ja) * 1984-10-05 1986-05-06 Satoshi Omura 消化管収縮運動促進剤
DE3689758T2 (de) * 1985-08-31 1994-08-18 Kitasato Inst Erythromycinderivat und Verfahren zu dessen Herstellung.
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
EP0559896B1 (en) * 1990-11-28 1997-08-27 Taisho Pharmaceutical Co. Ltd 6-o-methylerythromycin a derivative
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
IL124459A0 (en) * 1995-12-14 1998-12-06 Merck & Co Inc Antagonists of gonadotropin releasing hormone
IL126625A0 (en) * 1996-05-07 1999-08-17 Abbott Lab 6-o-substituted erythromycin compounds and method for making same

Also Published As

Publication number Publication date
EP1066304A1 (en) 2001-01-10
BG104844A (en) 2001-07-31
HUP0102011A2 (hu) 2001-11-28
CA2325521A1 (en) 1999-10-07
BR9909080A (pt) 2000-12-12
HUP0102011A3 (en) 2003-07-28
SK13972000A3 (sk) 2001-07-10
EP1066304B1 (en) 2005-02-23
CN1307584A (zh) 2001-08-08
JP2002509937A (ja) 2002-04-02
IL138219A0 (en) 2001-10-31
KR20010034694A (ko) 2001-04-25
AU3067499A (en) 1999-10-18
DE69923835D1 (de) 2005-03-31
WO1999050275A2 (en) 1999-10-07
ATE289609T1 (de) 2005-03-15
US5955440A (en) 1999-09-21
WO1999050275A3 (en) 2001-02-22
PL348242A1 (en) 2002-05-20
ES2238828T3 (es) 2005-09-01
NO20004860L (no) 2000-11-24
TR200002767T2 (tr) 2001-05-21
DE69923835T2 (de) 2006-04-06
NO20004860D0 (no) 2000-09-27
PT1066304E (pt) 2005-06-30

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090311