YU23302A - Farmaceutski preparati fibrinolitičkog agensa - Google Patents

Farmaceutski preparati fibrinolitičkog agensa

Info

Publication number
YU23302A
YU23302A YU23302A YUP23302A YU23302A YU 23302 A YU23302 A YU 23302A YU 23302 A YU23302 A YU 23302A YU P23302 A YUP23302 A YU P23302A YU 23302 A YU23302 A YU 23302A
Authority
YU
Yugoslavia
Prior art keywords
fibrinolytic agent
pharmaceutical preparations
lyophilized
agent
lyophilized composition
Prior art date
Application number
YU23302A
Other languages
English (en)
Inventor
Brent Kendrick
Brian Peterson
Original Assignee
Amgen Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc. filed Critical Amgen Inc.
Publication of YU23302A publication Critical patent/YU23302A/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Farmaceutski preparati koji sadrže fibrolazu ili novo delujući trombolitik i cink stabilizatore u farmaceutski prihvatljivim puferima za primenu u lizi fibrinoznih ugrušaka.[Frozen and lyophilized compositions for a metalloproteinase fibrinolytic agent (fibrolase or NAT), a method for preparing the lyophilized composition, and a kit and method for reconstituting the lyophilized composition are described herein.
YU23302A 1999-10-01 2000-09-29 Farmaceutski preparati fibrinolitičkog agensa YU23302A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/411,335 US6440414B1 (en) 1999-10-01 1999-10-01 Pharmaceutical compositions of fibrinolytic agent

Publications (1)

Publication Number Publication Date
YU23302A true YU23302A (sh) 2005-06-10

Family

ID=23628514

Family Applications (1)

Application Number Title Priority Date Filing Date
YU23302A YU23302A (sh) 1999-10-01 2000-09-29 Farmaceutski preparati fibrinolitičkog agensa

Country Status (28)

Country Link
US (4) US6440414B1 (sh)
EP (2) EP1438967A3 (sh)
JP (1) JP2003510369A (sh)
KR (1) KR100717435B1 (sh)
CN (2) CN101209347A (sh)
AT (1) ATE262923T1 (sh)
AU (1) AU769313B2 (sh)
BG (1) BG106578A (sh)
BR (1) BR0014420A (sh)
CA (1) CA2385966A1 (sh)
CZ (1) CZ20021033A3 (sh)
DE (2) DE60009529T2 (sh)
DK (1) DK1220685T3 (sh)
EA (2) EA004627B1 (sh)
ES (2) ES2224917T1 (sh)
HK (1) HK1049112B (sh)
HU (1) HUP0202654A3 (sh)
IL (1) IL148842A0 (sh)
MX (1) MXPA02003197A (sh)
NO (1) NO20021500L (sh)
NZ (4) NZ540967A (sh)
PL (1) PL355016A1 (sh)
PT (1) PT1220685E (sh)
SG (1) SG148823A1 (sh)
SK (1) SK4242002A3 (sh)
WO (1) WO2001024817A2 (sh)
YU (1) YU23302A (sh)
ZA (1) ZA200202400B (sh)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5149470B2 (ja) 1999-02-22 2013-02-20 バクスター・インターナショナル・インコーポレイテッド 新規のアルブミンを含有していない第ｖｉｉｉ因子処方物
US6261820B1 (en) 1999-10-01 2001-07-17 Amgen Inc. Fibronolytically active polypeptide
US6440414B1 (en) 1999-10-01 2002-08-27 Amgen Inc. Pharmaceutical compositions of fibrinolytic agent
US6455269B1 (en) * 1999-12-17 2002-09-24 Amgen, Inc. Method for localized administration of fibrinolytic metalloproteinases
US7033776B2 (en) 1999-12-17 2006-04-25 Amgen Inc. Method for treatment of indwelling catheter occlusion using fibrinolytic metalloproteinases
DE10149030A1 (de) * 2001-10-05 2003-04-10 Viscum Ag Stabile galenische gefriergetrocknete Arzneimittelzubereitung von rViscumin
US20050239746A1 (en) * 2002-02-01 2005-10-27 Penkler Lawrence J Pharmaceutical composition
WO2003068805A2 (en) * 2002-02-14 2003-08-21 Bayer Pharmaceuticals Corporation Formulation strategies in stabilizing peptides in organic solvents and in dried states
US6803046B2 (en) * 2002-08-16 2004-10-12 Bracco International B.V. Sincalide formulations
JP5201992B2 (ja) * 2004-12-15 2013-06-05 バイオビトラム・アクテイエボラーグ（パブリツク） ケラチノサイト増殖因子の治療用製剤
KR20080076907A (ko) * 2005-11-18 2008-08-20 에자이 알앤드디 매니지먼트 가부시키가이샤 신나미드 유도체의 제조 방법
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
KR100807692B1 (ko) * 2006-11-08 2008-02-28 신라대학교 산학협력단 혈전용해성 메탈로프로테아제 및 이를 포함하는 조성물
EP1958618A1 (de) 2007-02-15 2008-08-20 Octapharma AG Verfahren zur Gefriertrocknung mit optimierter Rekonstitution von Biopolymeren
CA2742328C (en) 2008-11-07 2019-02-26 Baxter International Inc. Factor viii formulations
KR20120050442A (ko) * 2009-07-10 2012-05-18 쓰롬보제닉스 엔.브이. 플라스미노겐 및 플라스민의 변이체
CN102000022A (zh) * 2010-11-23 2011-04-06 郑州大学 注射用重组双功能纤溶酶冻干制剂及其制备方法
CA2823491A1 (en) 2011-01-05 2012-07-12 Thrombogenics Nv Plasminogen and plasmin variants
US9644196B2 (en) 2011-08-12 2017-05-09 Thrombogenics Nv Plasminogen and plasmin variants
US20140212405A1 (en) 2013-01-28 2014-07-31 2294719 Ontario Limited Fibrinolytic/Proteolytic Treatment of Myofacial and Neuropathic Pain and Related Conditions
US11137409B2 (en) * 2014-11-06 2021-10-05 The Regents Of The University Of Colorado, A Body Corporate Identification of novel disease states using viscoelastic analysis in the presence of a thrombolytic agent
CN113382714A (zh) * 2019-01-06 2021-09-10 恩多全球美学有限公司 胶原酶制剂及其制备方法

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Also Published As

Publication number Publication date
HUP0202654A3 (en) 2003-11-28
EP1220685A2 (en) 2002-07-10
EP1220685B1 (en) 2004-03-31
EP1438967A3 (en) 2005-01-26
ES2224917T1 (es) 2005-03-16
NZ518007A (en) 2004-03-26
JP2003510369A (ja) 2003-03-18
EA004627B1 (ru) 2004-06-24
CA2385966A1 (en) 2001-04-12
US20060246053A1 (en) 2006-11-02
CZ20021033A3 (cs) 2003-06-18
US6440414B1 (en) 2002-08-27
KR20020053065A (ko) 2002-07-04
HUP0202654A2 (hu) 2002-12-28
EA006600B1 (ru) 2006-02-24
AU769313B2 (en) 2004-01-22
HK1049112A1 (en) 2003-05-02
EA200400182A1 (ru) 2004-08-26
BG106578A (bg) 2003-04-30
CN100353999C (zh) 2007-12-12
HK1049112B (zh) 2005-01-21
ATE262923T1 (de) 2004-04-15
DE04007657T1 (de) 2005-01-13
AU7743000A (en) 2001-05-10
CN1402641A (zh) 2003-03-12
BR0014420A (pt) 2002-06-11
IL148842A0 (en) 2002-09-12
NO20021500D0 (no) 2002-03-26
US7244426B2 (en) 2007-07-17
NZ540967A (en) 2007-02-23
DE60009529D1 (de) 2004-05-06
SG148823A1 (en) 2009-01-29
US7138114B2 (en) 2006-11-21
ZA200202400B (en) 2003-05-28
DK1220685T3 (da) 2004-08-02
US7311908B2 (en) 2007-12-25
NZ530959A (en) 2005-08-26
US20020192207A1 (en) 2002-12-19
WO2001024817A2 (en) 2001-04-12
EA200200396A1 (ru) 2002-10-31
US20060263347A1 (en) 2006-11-23
MXPA02003197A (es) 2002-09-30
EP1438967A2 (en) 2004-07-21
NZ550200A (en) 2008-04-30
DE60009529T2 (de) 2005-04-14
PT1220685E (pt) 2004-08-31
CN101209347A (zh) 2008-07-02
SK4242002A3 (en) 2003-08-05
WO2001024817A3 (en) 2001-10-18
NO20021500L (no) 2002-05-27
PL355016A1 (en) 2004-03-22
ES2218228T3 (es) 2004-11-16
KR100717435B1 (ko) 2007-05-14

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