IL98478A0 - Hybrid fibrinolytic enzyme,its preparation and pharmaceutical compositions containing it - Google Patents
Hybrid fibrinolytic enzyme,its preparation and pharmaceutical compositions containing itInfo
- Publication number
- IL98478A0 IL98478A0 IL98478A IL9847891A IL98478A0 IL 98478 A0 IL98478 A0 IL 98478A0 IL 98478 A IL98478 A IL 98478A IL 9847891 A IL9847891 A IL 9847891A IL 98478 A0 IL98478 A0 IL 98478A0
- Authority
- IL
- Israel
- Prior art keywords
- hybrid
- preparation
- pharmaceutical compositions
- compositions containing
- fibrinolytic enzyme
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909013345A GB9013345D0 (en) | 1990-06-14 | 1990-06-14 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
IL98478A0 true IL98478A0 (en) | 1992-07-15 |
Family
ID=10677652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL98478A IL98478A0 (en) | 1990-06-14 | 1991-06-13 | Hybrid fibrinolytic enzyme,its preparation and pharmaceutical compositions containing it |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0535037A1 (en) |
JP (1) | JPH05506363A (en) |
KR (1) | KR930701607A (en) |
AU (1) | AU648567B2 (en) |
CA (1) | CA2085224A1 (en) |
GB (1) | GB9013345D0 (en) |
IE (1) | IE911999A1 (en) |
IL (1) | IL98478A0 (en) |
NZ (1) | NZ238506A (en) |
PT (1) | PT97983A (en) |
WO (1) | WO1991019793A2 (en) |
ZA (1) | ZA914520B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3888099A (en) * | 1998-12-02 | 2000-06-19 | Oklahoma Medical Research Foundation | Human plasminogen activator |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ191320A (en) * | 1978-09-07 | 1982-09-14 | Beecham Group Ltd | In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions |
GB8334498D0 (en) * | 1983-12-24 | 1984-02-01 | Beecham Group Plc | Compounds |
DK359888A (en) * | 1987-07-01 | 1989-01-02 | Beecham Group Plc | FIBRINOLYTIC ENZYM |
GB9019120D0 (en) * | 1990-09-01 | 1990-10-17 | Beecham Group Plc | Novel compounds |
-
1990
- 1990-06-14 GB GB909013345A patent/GB9013345D0/en active Pending
-
1991
- 1991-06-12 CA CA002085224A patent/CA2085224A1/en not_active Abandoned
- 1991-06-12 EP EP91910869A patent/EP0535037A1/en not_active Withdrawn
- 1991-06-12 WO PCT/GB1991/000945 patent/WO1991019793A2/en not_active Application Discontinuation
- 1991-06-12 AU AU80681/91A patent/AU648567B2/en not_active Ceased
- 1991-06-12 KR KR1019920703217A patent/KR930701607A/en not_active Application Discontinuation
- 1991-06-12 ZA ZA914520A patent/ZA914520B/en unknown
- 1991-06-12 NZ NZ238506A patent/NZ238506A/en unknown
- 1991-06-12 IE IE199991A patent/IE911999A1/en unknown
- 1991-06-12 JP JP91510746A patent/JPH05506363A/en active Pending
- 1991-06-13 IL IL98478A patent/IL98478A0/en unknown
- 1991-06-14 PT PT97983A patent/PT97983A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NZ238506A (en) | 1993-07-27 |
KR930701607A (en) | 1993-06-12 |
ZA914520B (en) | 1992-12-30 |
IE911999A1 (en) | 1991-12-18 |
GB9013345D0 (en) | 1990-08-08 |
PT97983A (en) | 1992-04-30 |
WO1991019793A3 (en) | 1992-01-23 |
JPH05506363A (en) | 1993-09-22 |
AU648567B2 (en) | 1994-04-28 |
EP0535037A1 (en) | 1993-04-07 |
AU8068191A (en) | 1992-01-07 |
CA2085224A1 (en) | 1991-12-15 |
WO1991019793A2 (en) | 1991-12-26 |
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