SG127738A1 - Heterocyclic compounds based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, pharmaceutical preparations containing these compounds - Google Patents
Heterocyclic compounds based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, pharmaceutical preparations containing these compoundsInfo
- Publication number
- SG127738A1 SG127738A1 SG200405059A SG200405059A SG127738A1 SG 127738 A1 SG127738 A1 SG 127738A1 SG 200405059 A SG200405059 A SG 200405059A SG 200405059 A SG200405059 A SG 200405059A SG 127738 A1 SG127738 A1 SG 127738A1
- Authority
- SG
- Singapore
- Prior art keywords
- preparation
- drugs
- methods
- compounds
- pharmaceutical preparations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physical Education & Sports Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CZ20012818A CZ294535B6 (cs) | 2001-08-02 | 2001-08-02 | Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující |
Publications (1)
Publication Number | Publication Date |
---|---|
SG127738A1 true SG127738A1 (en) | 2006-12-29 |
Family
ID=5473504
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG200405059A SG127738A1 (en) | 2001-08-02 | 2002-08-01 | Heterocyclic compounds based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, pharmaceutical preparations containing these compounds |
SG200403857A SG119228A1 (en) | 2001-08-02 | 2002-08-01 | See under remarks |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG200403857A SG119228A1 (en) | 2001-08-02 | 2002-08-01 | See under remarks |
Country Status (20)
Country | Link |
---|---|
US (2) | US7279482B2 (ru) |
EP (1) | EP1419157B1 (ru) |
JP (1) | JP2005508386A (ru) |
KR (1) | KR100939147B1 (ru) |
CN (1) | CN1556808B (ru) |
AU (3) | AU2002363362B2 (ru) |
BR (1) | BR0211597A (ru) |
CA (1) | CA2455972C (ru) |
CZ (1) | CZ294535B6 (ru) |
HU (1) | HUP0401407A3 (ru) |
IL (1) | IL160136A0 (ru) |
MX (1) | MXPA04000936A (ru) |
NO (1) | NO329434B1 (ru) |
NZ (1) | NZ531086A (ru) |
PL (1) | PL368299A1 (ru) |
RS (1) | RS52389B (ru) |
RU (1) | RU2302421C2 (ru) |
SG (2) | SG127738A1 (ru) |
WO (1) | WO2003040144A2 (ru) |
ZA (1) | ZA200401461B (ru) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1244668B1 (en) * | 2000-01-07 | 2006-04-05 | Universitaire Instelling Antwerpen | Purine derivatives, process for their preparation and use thereof |
FR2818642B1 (fr) * | 2000-12-26 | 2005-07-15 | Hoechst Marion Roussel Inc | Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilistion |
CZ294535B6 (cs) * | 2001-08-02 | 2005-01-12 | Ústav Experimentální Botaniky Avčr | Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující |
TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
US7273864B2 (en) * | 2002-10-15 | 2007-09-25 | The Scripps Research Institute | Compositions and methods for inducing osteogenesis |
SG145748A1 (en) * | 2003-08-15 | 2008-09-29 | Irm Llc | 6-substituted anilino purines as rtk inhibitors |
AU2011213790B2 (en) * | 2003-10-03 | 2013-05-02 | The General Hospital Corporation | Methods for altering mRNA splicing and treating familial dysautonomia and other mechanistically related disorders |
US7737110B2 (en) | 2003-10-03 | 2010-06-15 | The General Hospital Corporation | Methods for altering mRNA splicing and treating familial dysautonomia and other mechanistically related disorders |
JP2010516774A (ja) * | 2007-01-26 | 2010-05-20 | アイアールエム・リミテッド・ライアビリティ・カンパニー | マラリア原虫関連疾患を処置するためのキナーゼ阻害剤としてのプリン化合物および組成物 |
NZ579248A (en) * | 2007-03-28 | 2011-08-26 | Neurosearch As | Purinyl derivatives and their use as potassium channel modulators |
CZ302225B6 (cs) * | 2007-07-04 | 2010-12-29 | Univerzita Palackého v Olomouci | Substituované 6-anilinopurinové deriváty jako inhibitory cytokinin oxidasy a prípravky obsahující tyto slouceniny |
CZ300774B6 (cs) * | 2007-10-05 | 2009-08-05 | Univerzita Palackého | Substituované 6-(alkylbenzylamino)purinové deriváty pro použití jako antagonisté cytokininových receptoru a prípravky obsahující tyto slouceniny |
EA019869B1 (ru) | 2007-11-28 | 2014-06-30 | Дана Фарбер Кансер Инститьют, Инк. | Низкомолекулярные миристатные ингибиторы тирозинкиназы bcr-abl и способы их применения |
CZ302623B6 (cs) | 2009-04-22 | 2011-08-03 | Univerzita Palackého | Oxalátokomplexy platiny s deriváty N6-benzyladeninu, zpusob jejich prípravy a použití techto komplexu jako léciv v protinádorové terapii |
KR101763656B1 (ko) | 2009-06-29 | 2017-08-01 | 인사이트 홀딩스 코포레이션 | Pi3k 저해물질로서의 피리미디논 |
CZ302618B6 (cs) | 2009-09-10 | 2011-08-03 | Univerzita Palackého | Cyklobutan-1,1-dikarboxylátokomplexy platiny s deriváty N6-benzyladeninu, zpusoby jejich prípravy a použití techto komplexu jako léciv v protinádorové terapii |
US9238653B2 (en) * | 2009-09-29 | 2016-01-19 | Board Of Regents, The University Of Texas System | Antimalarial agents that are inhibitors of dihydroorotate dehydrogenase |
TW201130842A (en) * | 2009-12-18 | 2011-09-16 | Incyte Corp | Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors |
WO2011075643A1 (en) * | 2009-12-18 | 2011-06-23 | Incyte Corporation | Substituted heteroaryl fused derivatives as pi3k inhibitors |
JP5816678B2 (ja) | 2010-04-14 | 2015-11-18 | インサイト・コーポレイションIncyte Corporation | PI3Kδ阻害剤としての縮合誘導体 |
WO2011163195A1 (en) | 2010-06-21 | 2011-12-29 | Incyte Corporation | Fused pyrrole derivatives as pi3k inhibitors |
CZ2010670A3 (cs) | 2010-09-07 | 2012-03-14 | Univerzita Palackého v Olomouci | Použití 6-substituovaných 9-halogenalkyl purinu pro regulaci rustu a vývoje rostlin, rostlinných orgánu a bunek, nové 6-substituované 9-halogenalkyl puriny |
JP5961187B2 (ja) | 2010-12-20 | 2016-08-02 | インサイト・ホールディングス・コーポレイションIncyte Holdings Corporation | Pi3k阻害剤としてのn−(1−(置換フェニル)エチル)−9h−プリン−6−アミン |
WO2012125629A1 (en) | 2011-03-14 | 2012-09-20 | Incyte Corporation | Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors |
US9126948B2 (en) | 2011-03-25 | 2015-09-08 | Incyte Holdings Corporation | Pyrimidine-4,6-diamine derivatives as PI3K inhibitors |
WO2012142029A2 (en) | 2011-04-10 | 2012-10-18 | Florida A&M University | Serms for the treatment of estrogen receptor-mediated disorders |
WO2013033569A1 (en) | 2011-09-02 | 2013-03-07 | Incyte Corporation | Heterocyclylamines as pi3k inhibitors |
AR090548A1 (es) | 2012-04-02 | 2014-11-19 | Incyte Corp | Azaheterociclobencilaminas biciclicas como inhibidores de pi3k |
CN104755695B (zh) | 2012-10-26 | 2018-07-03 | 埃克森美孚上游研究公司 | 用于流量控制的井下接头组件以及用于完成井筒的方法 |
CZ306894B6 (cs) | 2013-02-08 | 2017-08-30 | Univerzita PalackĂ©ho v Olomouci | 2-Substituované-6-biarylmethylamino-9-cyklopentyl-9H-purinové deriváty, jejich použití jako léčiva a farmaceutické přípravky tyto sloučeniny obsahující |
US9938279B2 (en) * | 2013-04-09 | 2018-04-10 | Energenesis Biomedical Co., Ltd | Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) |
RU2529817C1 (ru) * | 2013-07-08 | 2014-09-27 | Владимир Иванович Петров | 9-[2-(4-изопропилфенокси)этил]аденин, обладающий антидепрессантным и противострессорным действием |
US9816361B2 (en) | 2013-09-16 | 2017-11-14 | Exxonmobil Upstream Research Company | Downhole sand control assembly with flow control, and method for completing a wellbore |
CN116492347A (zh) * | 2013-09-18 | 2023-07-28 | 华安医学股份有限公司 | 一种活化ampk的化合物及其用途 |
WO2015191677A1 (en) | 2014-06-11 | 2015-12-17 | Incyte Corporation | Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors |
CZ306984B6 (cs) | 2014-12-15 | 2017-11-01 | Ústav experimentální botaniky AV ČR, v. v. i. | 6,8-Disubstituované-9-(heterocyklyl)puriny, přípravky obsahující tyto deriváty a jejich použití v kosmetických a medicínských aplikacích |
ES2928714T3 (es) | 2015-01-16 | 2022-11-22 | Massachusetts Gen Hospital | Compuestos para mejorar el empalme del ARNm |
NZ734993A (en) | 2015-02-27 | 2024-03-22 | Incyte Holdings Corp | Salts of pi3k inhibitor and processes for their preparation |
US9988401B2 (en) | 2015-05-11 | 2018-06-05 | Incyte Corporation | Crystalline forms of a PI3K inhibitor |
US9732097B2 (en) | 2015-05-11 | 2017-08-15 | Incyte Corporation | Process for the synthesis of a phosphoinositide 3-kinase inhibitor |
US10647713B2 (en) * | 2016-10-21 | 2020-05-12 | Nimbus Lakshmi, Inc. | TYK2 inhibitors and uses thereof |
CN106632339B (zh) * | 2016-12-16 | 2018-11-27 | 温州医科大学 | 一种6-取代-9h-嘌呤类衍生物及其制备方法和应用 |
CN106632338B (zh) * | 2016-12-16 | 2018-11-27 | 温州医科大学 | 一种9-取代-n-(2-氯苄基)嘌呤-6-胺类衍生物及其制备方法和应用 |
AU2018246138A1 (en) * | 2017-03-27 | 2019-08-29 | The Regents Of The University Of California | Compositions and method of treating cancer |
CZ307868B6 (cs) * | 2017-04-28 | 2019-07-10 | Univerzita PalackĂ©ho v Olomouci | Deriváty 9-(2-oxacykloalkyl)-9H-purin-2,6-diaminu, přípravky obsahující tyto deriváty a jejich použití |
JP6510621B2 (ja) * | 2017-11-29 | 2019-05-08 | 華安醫學股分有限公司Energenesis Biomedical Co., Ltd. | 活性化ampkの化合物及びその使用 |
CN107903274A (zh) * | 2017-12-28 | 2018-04-13 | 窦玉玲 | 一种胺类化合物及其在抗肿瘤药物中的应用 |
JP6877479B2 (ja) * | 2019-04-04 | 2021-05-26 | 華安醫學股分有限公司Energenesis Biomedical Co., Ltd. | 活性化ampkの化合物及びその使用 |
CZ308865B6 (cs) * | 2020-05-17 | 2021-07-21 | Ústav experimentální botaniky AV ČR, v. v. i. | Mesylátová sůl para-topolinu, přípravky ji obsahující, a její použití |
CN111777612B (zh) * | 2020-06-05 | 2022-04-19 | 广东达元绿洲食品安全科技股份有限公司 | 一种6-苄基腺嘌呤半抗原、人工抗原及其在免疫检测中的应用 |
EP4178959A1 (en) | 2020-07-13 | 2023-05-17 | Univerzita Palackého v Olomouci | Nitrogen heterocyclic cytokinin derivatives, compositions containing these derivatives and use thereof |
CN112656800A (zh) * | 2021-02-09 | 2021-04-16 | 中国科学院昆明动物研究所 | 巯嘌呤及其衍生物在制备解除恶性肿瘤免疫抑制药物中的用途 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996040142A1 (en) * | 1995-06-07 | 1996-12-19 | Pfizer Inc. | Heterocyclic ring-fused pyrimidine derivatives |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3041340A (en) * | 1962-06-26 | Method of preparing substituted | ||
US2956998A (en) * | 1960-10-18 | Adenine derivatives and process | ||
US3213095A (en) * | 1963-04-04 | 1965-10-19 | American Cyanamid Co | N-benzylation of adenine |
US3321293A (en) * | 1964-04-29 | 1967-05-23 | Union Carbide Corp | Method of defoliating cotton plants |
JPH0690429B2 (ja) * | 1986-05-26 | 1994-11-14 | コニカ株式会社 | 直接ポジ型ハロゲン化銀写真感光材料 |
US5371089A (en) * | 1987-02-26 | 1994-12-06 | Senetek, Plc | Method and composition for ameliorating the adverse effects of aging |
US5164394A (en) * | 1989-06-08 | 1992-11-17 | Senetek, Plc | Method for treating hyperproliferative skin diseases |
BR9107307A (pt) * | 1991-05-16 | 1994-06-14 | Senetek Plc | Processo e composiçao para atenuar os efeitos adversos do envelhecimento em células de mamiferos |
AU659861B2 (en) * | 1991-09-10 | 1995-06-01 | Sansho Seiyaku Co., Ltd. | Preparation for promoting hair growth |
JP2636118B2 (ja) * | 1991-09-10 | 1997-07-30 | 三省製薬株式会社 | 育毛剤 |
JPH07233037A (ja) * | 1993-12-29 | 1995-09-05 | Sansho Seiyaku Co Ltd | 皮膚化粧料 |
US6498163B1 (en) * | 1997-02-05 | 2002-12-24 | Warner-Lambert Company | Pyrido[2,3-D]pyrimidines and 4-aminopyrimidines as inhibitors of cellular proliferation |
EP1244668B1 (en) * | 2000-01-07 | 2006-04-05 | Universitaire Instelling Antwerpen | Purine derivatives, process for their preparation and use thereof |
CZ294535B6 (cs) * | 2001-08-02 | 2005-01-12 | Ústav Experimentální Botaniky Avčr | Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující |
AU2003247667A1 (en) * | 2002-07-01 | 2004-01-19 | University Of Rochester Medical Center | Method for determination of likelihood of occurrence of preterm labor in pregnant females |
-
2001
- 2001-08-02 CZ CZ20012818A patent/CZ294535B6/cs not_active IP Right Cessation
-
2002
- 2002-08-01 AU AU2002363362A patent/AU2002363362B2/en not_active Ceased
- 2002-08-01 PL PL02368299A patent/PL368299A1/xx not_active IP Right Cessation
- 2002-08-01 KR KR1020047001539A patent/KR100939147B1/ko not_active IP Right Cessation
- 2002-08-01 IL IL16013602A patent/IL160136A0/xx unknown
- 2002-08-01 US US10/485,091 patent/US7279482B2/en not_active Expired - Fee Related
- 2002-08-01 CA CA2455972A patent/CA2455972C/en not_active Expired - Fee Related
- 2002-08-01 SG SG200405059A patent/SG127738A1/en unknown
- 2002-08-01 NZ NZ531086A patent/NZ531086A/en not_active IP Right Cessation
- 2002-08-01 CN CN028185528A patent/CN1556808B/zh not_active Expired - Fee Related
- 2002-08-01 MX MXPA04000936A patent/MXPA04000936A/es active IP Right Grant
- 2002-08-01 EP EP02750769.8A patent/EP1419157B1/en not_active Expired - Lifetime
- 2002-08-01 SG SG200403857A patent/SG119228A1/en unknown
- 2002-08-01 BR BR0211597-2A patent/BR0211597A/pt not_active IP Right Cessation
- 2002-08-01 RU RU2004105843/04A patent/RU2302421C2/ru not_active IP Right Cessation
- 2002-08-01 WO PCT/CZ2002/000045 patent/WO2003040144A2/en active IP Right Grant
- 2002-08-01 JP JP2003542190A patent/JP2005508386A/ja active Pending
- 2002-08-01 RS YU8904A patent/RS52389B/en unknown
- 2002-08-01 HU HU0401407A patent/HUP0401407A3/hu unknown
-
2004
- 2004-02-02 NO NO20040469A patent/NO329434B1/no not_active IP Right Cessation
- 2004-02-23 ZA ZA2004/01461A patent/ZA200401461B/en unknown
-
2007
- 2007-07-18 US US11/779,828 patent/US8552013B2/en not_active Expired - Fee Related
-
2008
- 2008-08-12 AU AU2008203837A patent/AU2008203837A1/en not_active Abandoned
- 2008-08-12 AU AU2008203838A patent/AU2008203838B2/en not_active Ceased
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996040142A1 (en) * | 1995-06-07 | 1996-12-19 | Pfizer Inc. | Heterocyclic ring-fused pyrimidine derivatives |
Non-Patent Citations (3)
Title |
---|
PHOSPHORUS PENTOXIDE IN ORGANIC SYNTHESIS.XXXVII.SYNTHESIS OF 2-AMINO-6- ARYLAMINOPURINES * |
STUDIES ON HETEROCYCLIC COMPOUNDS.III, RING CLOSURE REA * |
THE MASS SPECTROMETRY OF 2-AMINO-6-ARYL-AMINOPURINES * |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG127738A1 (en) | Heterocyclic compounds based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, pharmaceutical preparations containing these compounds | |
DE60038183D1 (de) | Verbindungen und zusammensetzungen zur abgabe aktiver wirkstoffe | |
BG103417A (en) | Condensed pyrimidine bicyclic derivatives | |
YU49202A (sh) | Benzazolski derivati i njihova upotreba kao modulatora jnk | |
TR200100894T2 (tr) | Aril ikameli propanolamin türevleri, imalat yöntemleri, ilaç maddeleri, kullanımları. | |
BR0315547A (pt) | Derivados de quinolina como antagonistas de crth2 | |
GEP20033025B (en) | 4,4-Biarylpiperidine Derivatives with Opioid Receptor Activity | |
ATE316083T1 (de) | Adamantanderivate | |
AU2001296865A1 (en) | (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents | |
MXPA04004601A (es) | Derivados de sulfonamidas, su preparacion y su aplicacion como medicamentos. | |
NO20021859D0 (no) | Nye digosakkarider, deres fremstilling samt farmasöytiske preparater | |
TW200510392A (en) | Chemical compounds | |
SE0302573D0 (sv) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
SE0300908D0 (sv) | Azaindole derivatives, preparations thereof, uses thereof and compositions containing them | |
SE9903997D0 (sv) | New compounds | |
TW200504029A (en) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
MY129437A (en) | Drug formulation having controlled release of active compound | |
MXPA05013050A (es) | Derivados de bencimidazol, composiciones que los contienen preparacion de los mismos y usos de los mismos. | |
EP0321968A3 (en) | Compounds active on the cardiovascular system | |
SE0302570D0 (sv) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
SE0302572D0 (sv) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
TW200740440A (en) | Novel combinations of medicaments for the treatment of respiratory diseases containing long-acting beta-agonists and at least one additional active ingredient | |
ATE241624T1 (de) | Benzo(f)naphthyridinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammenstzungen | |
WO2000058328A3 (de) | Avermectinderivate | |
SE9803107D0 (sv) | Novel Compunds |