SG11201808783XA - Cd80 variant immunomodulatory proteins and uses thereof - Google Patents
Cd80 variant immunomodulatory proteins and uses thereofInfo
- Publication number
- SG11201808783XA SG11201808783XA SG11201808783XA SG11201808783XA SG11201808783XA SG 11201808783X A SG11201808783X A SG 11201808783XA SG 11201808783X A SG11201808783X A SG 11201808783XA SG 11201808783X A SG11201808783X A SG 11201808783XA SG 11201808783X A SG11201808783X A SG 11201808783XA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- suite
- proteins
- variant
- elliott
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 230000002519 immonomodulatory effect Effects 0.000 title abstract 4
- 101000914484 Homo sapiens T-lymphocyte activation antigen CD80 Proteins 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102100027222 T-lymphocyte activation antigen CD80 Human genes 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000000771 oncological effect Effects 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70532—B7 molecules, e.g. CD80, CD86
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662323595P | 2016-04-15 | 2016-04-15 | |
US201662394743P | 2016-09-14 | 2016-09-14 | |
US201662410844P | 2016-10-20 | 2016-10-20 | |
US201762472570P | 2017-03-16 | 2017-03-16 | |
US201762475201P | 2017-03-22 | 2017-03-22 | |
PCT/US2017/027817 WO2017181152A2 (en) | 2016-04-15 | 2017-04-14 | Cd80 variant immunomodulatory proteins and uses thereof |
Publications (1)
Publication Number | Publication Date |
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SG11201808783XA true SG11201808783XA (en) | 2018-11-29 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201808783XA SG11201808783XA (en) | 2016-04-15 | 2017-04-14 | Cd80 variant immunomodulatory proteins and uses thereof |
Country Status (12)
Country | Link |
---|---|
US (5) | US11078282B2 (ja) |
EP (1) | EP3443000A2 (ja) |
JP (2) | JP2019521643A (ja) |
KR (2) | KR20230101931A (ja) |
CN (1) | CN109715657A (ja) |
AU (2) | AU2017248830B2 (ja) |
CA (1) | CA3019202A1 (ja) |
IL (2) | IL310729A (ja) |
MA (1) | MA43552A (ja) |
NZ (1) | NZ746934A (ja) |
SG (1) | SG11201808783XA (ja) |
WO (1) | WO2017181152A2 (ja) |
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KR20190006495A (ko) | 2019-01-18 |
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NZ746934A (en) | 2023-11-24 |
JP2022109915A (ja) | 2022-07-28 |
MA43552A (fr) | 2018-11-07 |
WO2017181152A2 (en) | 2017-10-19 |
US11359022B2 (en) | 2022-06-14 |
EP3443000A2 (en) | 2019-02-20 |
US20220162319A1 (en) | 2022-05-26 |
AU2017248830A1 (en) | 2018-10-25 |
IL262366B1 (en) | 2024-03-01 |
WO2017181152A3 (en) | 2018-02-15 |
CN109715657A (zh) | 2019-05-03 |
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