SG11201806685VA - Method for preparing pyrrolo[3,2-d]pyrimidine compound, and intermediates thereof - Google Patents

Method for preparing pyrrolo[3,2-d]pyrimidine compound, and intermediates thereof

Info

Publication number
SG11201806685VA
SG11201806685VA SG11201806685VA SG11201806685VA SG11201806685VA SG 11201806685V A SG11201806685V A SG 11201806685VA SG 11201806685V A SG11201806685V A SG 11201806685VA SG 11201806685V A SG11201806685V A SG 11201806685VA SG 11201806685V A SG11201806685V A SG 11201806685VA
Authority
SG
Singapore
Prior art keywords
intermediates
pyrimidine compound
pyrrolo
preparing
preparing pyrrolo
Prior art date
Application number
SG11201806685VA
Other languages
English (en)
Inventor
Zhaozhong Ding
Fei Sun
Yinghu Hu
Yilong Zhou
Rui Zhao
Ling Yang
Original Assignee
Chia Tai Tianqing Pharmaceutical Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chia Tai Tianqing Pharmaceutical Group Co Ltd filed Critical Chia Tai Tianqing Pharmaceutical Group Co Ltd
Publication of SG11201806685VA publication Critical patent/SG11201806685VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
SG11201806685VA 2016-02-05 2017-02-04 Method for preparing pyrrolo[3,2-d]pyrimidine compound, and intermediates thereof SG11201806685VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201610082028.3A CN107043378A (zh) 2016-02-05 2016-02-05 一种吡咯并[3,2-d]嘧啶类化合物的制备方法及其中间体
PCT/CN2017/072893 WO2017133686A1 (zh) 2016-02-05 2017-02-04 一种吡咯并[3,2-d]嘧啶类化合物的制备方法及其中间体

Publications (1)

Publication Number Publication Date
SG11201806685VA true SG11201806685VA (en) 2018-09-27

Family

ID=59500148

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201806685VA SG11201806685VA (en) 2016-02-05 2017-02-04 Method for preparing pyrrolo[3,2-d]pyrimidine compound, and intermediates thereof

Country Status (29)

Country Link
US (2) US10654856B2 (pt)
EP (1) EP3412673B1 (pt)
JP (1) JP6877449B2 (pt)
KR (1) KR102371500B1 (pt)
CN (2) CN107043378A (pt)
AR (1) AR107549A1 (pt)
AU (1) AU2017214134B2 (pt)
BR (1) BR112018015879B1 (pt)
CA (1) CA3013520C (pt)
CL (1) CL2018002094A1 (pt)
DK (1) DK3412673T3 (pt)
EA (1) EA034581B1 (pt)
ES (1) ES2852323T3 (pt)
HK (1) HK1259183A1 (pt)
HR (1) HRP20210103T1 (pt)
HU (1) HUE053455T2 (pt)
IL (1) IL260999B (pt)
LT (1) LT3412673T (pt)
MX (1) MX2018009502A (pt)
MY (1) MY190551A (pt)
NZ (1) NZ744885A (pt)
PH (1) PH12018501642A1 (pt)
PL (1) PL3412673T3 (pt)
PT (1) PT3412673T (pt)
SG (1) SG11201806685VA (pt)
SI (1) SI3412673T1 (pt)
TW (1) TW201728590A (pt)
UA (1) UA124100C2 (pt)
WO (1) WO2017133686A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107043380A (zh) * 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种tlr7激动剂的马来酸盐、其晶型c、晶型d、晶型e、制备方法和用途
MX2021009496A (es) 2019-02-08 2021-09-08 Progeneer Inc Complejo de colesterol-agonista del receptor 7 u 8 tipo larga distancia, y uso del mismo.
AU2021231160A1 (en) 2020-03-02 2022-09-22 Progeneer Inc. Live-pathogen-mimetic nanoparticles based on pathogen cell wall skeleton, and production method thereof
CN116056725A (zh) 2020-08-04 2023-05-02 蛋白科技先鋒 活性位点暂时灭活的功能性药物与Toll样受体7或8激动剂的缀合物及其用途
US20230346924A1 (en) 2020-08-04 2023-11-02 Progeneer Inc. Mrna vaccine comprising adjuvant capable of kinetic control
US20230355750A1 (en) 2020-08-04 2023-11-09 Progeneer Inc. Kinetically acting adjuvant ensemble
WO2023137035A1 (en) 2022-01-12 2023-07-20 Denali Therapeutics Inc. Crystalline forms of (s)-5-benzyl-n-(5-methyl-4-oxo-2, 3,4,5- tetrahydropyrido [3,2-b] [l,4]oxazepin-3-yl)-4h-l,2,4-triazole-3-carboxamide

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009082247A1 (en) * 2007-12-21 2009-07-02 Industrial Research Limited Process for preparing immucillins having a methylene link
PT2364314E (pt) 2008-12-09 2014-06-09 Gilead Sciences Inc Moduladores de recetores toll-like
LT2906563T (lt) * 2012-10-10 2018-06-11 Janssen Sciences Ireland Uc Pirolo[3,2-d]pirimidino dariniai virusinių infekcijų ir kitų ligų gydymui
BR112015011447A2 (pt) 2012-11-20 2017-07-11 Glaxosmithkline Llc composto da fórmula i, composição farmacêutica e de vacina, e, uso de um composto
CA2892218A1 (en) * 2012-11-20 2014-05-30 Glaxosmithkline Llc Novel compounds
EP3137470B1 (en) * 2014-05-01 2021-04-07 Novartis AG Compounds and compositions as toll-like receptor 7 agonists
WO2016023511A1 (zh) * 2014-08-15 2016-02-18 正大天晴药业集团股份有限公司 作为tlr7激动剂的吡咯并嘧啶化合物
CN105367576A (zh) 2014-08-15 2016-03-02 正大天晴药业集团股份有限公司 作为tlr7激动剂的吡咯并嘧啶化合物
BR112018008880B1 (pt) 2015-11-05 2023-01-17 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 7-(tiazol-5-il) pirrolopirimidina, seu uso, e composição farmacêutica
CN107043380A (zh) * 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种tlr7激动剂的马来酸盐、其晶型c、晶型d、晶型e、制备方法和用途
CN107043377A (zh) * 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种tlr7激动剂的三氟乙酸盐、晶型b及其制备方法、药物组合物和用途
CN107043379A (zh) * 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种tlr7激动剂的晶型a、其制备方法和医药用途

Also Published As

Publication number Publication date
HK1259183A1 (zh) 2019-11-29
PT3412673T (pt) 2021-02-15
UA124100C2 (uk) 2021-07-21
LT3412673T (lt) 2021-03-10
WO2017133686A1 (zh) 2017-08-10
JP6877449B2 (ja) 2021-05-26
US10654856B2 (en) 2020-05-19
EP3412673A1 (en) 2018-12-12
AU2017214134B2 (en) 2020-08-27
EA034581B1 (ru) 2020-02-21
CN107043378A (zh) 2017-08-15
PH12018501642B1 (en) 2019-06-03
CL2018002094A1 (es) 2018-12-07
BR112018015879A2 (pt) 2018-12-26
MY190551A (en) 2022-04-27
KR102371500B1 (ko) 2022-03-07
IL260999B (en) 2021-02-28
CA3013520A1 (en) 2017-08-10
JP2019505531A (ja) 2019-02-28
KR20180104724A (ko) 2018-09-21
CN108602832A (zh) 2018-09-28
EP3412673A4 (en) 2019-07-03
NZ744885A (en) 2022-07-01
TW201728590A (zh) 2017-08-16
PH12018501642A1 (en) 2019-06-03
AR107549A1 (es) 2018-05-09
EA201891769A1 (ru) 2019-04-30
BR112018015879B1 (pt) 2024-02-15
MX2018009502A (es) 2018-12-11
AU2017214134A1 (en) 2018-08-23
DK3412673T3 (da) 2021-01-18
EP3412673B1 (en) 2020-11-25
US20190040072A1 (en) 2019-02-07
ES2852323T3 (es) 2021-09-13
SI3412673T1 (sl) 2021-04-30
HUE053455T2 (hu) 2021-06-28
US20200239484A1 (en) 2020-07-30
CA3013520C (en) 2022-07-19
HRP20210103T1 (hr) 2021-03-05
CN108602832B (zh) 2020-10-09
PL3412673T3 (pl) 2021-07-26

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