ATE64618T1
(de)
|
1982-03-15 |
1991-07-15 |
Schering Corp |
Hybride dns, damit hergestellte bindungszusammensetzung und verfahren dafuer.
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US5869620A
(en)
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
US5091513A
(en)
|
1987-05-21 |
1992-02-25 |
Creative Biomolecules, Inc. |
Biosynthetic antibody binding sites
|
WO1991001752A1
(fr)
|
1989-07-27 |
1991-02-21 |
Fred Hutchinson Cancer Research Center |
Anticorps monoclonaux immunosuppresseurs, hybridomes et procedes de transplantation
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US5811267A
(en)
|
1990-10-29 |
1998-09-22 |
Chiron Corporation |
Isolated nucleic acid molecules encoding antigen binding sites of antibody molecules specific for cancer antigens
|
DE4118120A1
(de)
|
1991-06-03 |
1992-12-10 |
Behringwerke Ag |
Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
|
US6129914A
(en)
|
1992-03-27 |
2000-10-10 |
Protein Design Labs, Inc. |
Bispecific antibody effective to treat B-cell lymphoma and cell line
|
WO1994007921A1
(fr)
|
1992-09-25 |
1994-04-14 |
Commonwealth Scientific And Industrial Research Organisation |
Polypeptide se fixant a une cible
|
AU5670194A
(en)
|
1992-11-20 |
1994-06-22 |
Enzon, Inc. |
Linker for linked fusion polypeptides
|
ATE199392T1
(de)
|
1992-12-04 |
2001-03-15 |
Medical Res Council |
Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
|
SG55079A1
(en)
|
1992-12-11 |
1998-12-21 |
Dow Chemical Co |
Multivalent single chain antibodies
|
ATE241642T1
(de)
|
1993-02-04 |
2003-06-15 |
Denzyme Aps |
Verbessertes verfahren zur rückfaltung der proteine
|
US5747654A
(en)
|
1993-06-14 |
1998-05-05 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant disulfide-stabilized polypeptide fragments having binding specificity
|
US6476198B1
(en)
|
1993-07-13 |
2002-11-05 |
The Scripps Research Institute |
Multispecific and multivalent antigen-binding polypeptide molecules
|
WO1995009917A1
(fr)
|
1993-10-07 |
1995-04-13 |
The Regents Of The University Of California |
Anticorps bispecifiques et tetravalents, obtenus par genie genetique
|
IT1271461B
(it)
|
1993-12-01 |
1997-05-28 |
Menarini Ricerche Sud Spa |
Anticorpo monoclonale bispecifico anti-cd3/anti-egfr,processo per la produzione e suo uso.
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
BR9606706A
(pt)
|
1995-10-16 |
1999-04-06 |
Unilever Nv |
Análogo de fragmento de anticorpo biespecífico ou bivalente uso processo para produzir o mesmo
|
CA2259966A1
(fr)
|
1996-07-12 |
1998-01-22 |
Mcgill University |
Composes et procedes pour la modulation de l'adherence cellulaire
|
WO1998002462A1
(fr)
|
1996-07-16 |
1998-01-22 |
Morphosys Gesellschaft Für Proteinoptimierung Mbh |
Domaines de la superfamille des immunoglobulines et fragments presentant une solubilite accrue
|
WO1998041613A1
(fr)
|
1997-03-14 |
1998-09-24 |
Otten Gillis R |
Cytolyse ciblee de cellules cancereuses
|
US7951917B1
(en)
|
1997-05-02 |
2011-05-31 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
CN1203178C
(zh)
|
1997-10-27 |
2005-05-25 |
尤尼利弗公司 |
多价抗原结合蛋白
|
US6485910B1
(en)
|
1998-02-09 |
2002-11-26 |
Incyte Genomics, Inc. |
Ras association domain containing protein
|
WO1999042077A2
(fr)
|
1998-02-19 |
1999-08-26 |
Xcyte Therapies, Inc. |
Compositions et procedes de regulation de l'activation des lymphocytes
|
US6783961B1
(en)
|
1999-02-26 |
2004-08-31 |
Genset S.A. |
Expressed sequence tags and encoded human proteins
|
CZ121599A3
(cs)
|
1998-04-09 |
1999-10-13 |
Aventis Pharma Deutschland Gmbh |
Jednořetězcová molekula vázající několik antigenů, způsob její přípravy a léčivo obsahující tuto molekulu
|
IL138857A0
(en)
|
1998-04-21 |
2001-10-31 |
Micromet Ges For Biomedizinisc |
Cd19xcd3 specific polypeptides and uses thereof
|
DE19819846B4
(de)
|
1998-05-05 |
2016-11-24 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Multivalente Antikörper-Konstrukte
|
GB9812545D0
(en)
|
1998-06-10 |
1998-08-05 |
Celltech Therapeutics Ltd |
Biological products
|
DK1100830T3
(da)
|
1998-07-28 |
2004-01-19 |
Micromet Ag |
Heterominiantistoffer
|
ATE370967T1
(de)
|
1998-10-21 |
2007-09-15 |
Altor Bioscience Corp |
Polyspezifische bindemoleküle und deren verwendung
|
WO2001057188A2
(fr)
|
2000-02-03 |
2001-08-09 |
Hyseq, Inc. |
Nouveaux acides nucleiques et polypeptides
|
US20020142000A1
(en)
|
1999-01-15 |
2002-10-03 |
Digan Mary Ellen |
Anti-CD3 immunotoxins and therapeutic uses therefor
|
DE19905048A1
(de)
|
1999-02-08 |
2000-08-10 |
Gsf Forschungszentrum Umwelt |
Verwendung depletorisch oder mitogen wirkender Antikörper in der Immuntherapie
|
AU2001247616B2
(en)
|
2000-04-11 |
2007-06-14 |
Genentech, Inc. |
Multivalent antibodies and uses therefor
|
US20040180046A1
(en)
|
2000-04-26 |
2004-09-16 |
Jeff Himawan |
Bispecific molecules and uses thereof
|
US20040047854A1
(en)
|
2001-07-27 |
2004-03-11 |
Black Roy A. |
Human disintegrin protein
|
GB0025307D0
(en)
|
2000-10-16 |
2000-11-29 |
Celltech Chiroscience Ltd |
Biological products
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
US7319139B2
(en)
|
2001-01-29 |
2008-01-15 |
Biogen Idec, Inc. |
TAG-72 specific CH2 domain deleted antibodies
|
US20040053245A1
(en)
|
2001-02-05 |
2004-03-18 |
Tang Y. Tom |
Novel nucleic acids and polypeptides
|
EP1455820A2
(fr)
|
2001-03-09 |
2004-09-15 |
William Herman |
Ligands cibles
|
AU2002247826A1
(en)
|
2001-03-13 |
2002-09-24 |
University College London |
Specific binding members
|
WO2002097395A2
(fr)
|
2001-05-31 |
2002-12-05 |
Chiron Corporation |
Utilisation de p-cadherine comme cible dans la therapie anticancereuse
|
US7189507B2
(en)
|
2001-06-18 |
2007-03-13 |
Pdl Biopharma, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
DK1399484T3
(da)
|
2001-06-28 |
2010-11-08 |
Domantis Ltd |
Dobbelt-specifik ligand og anvendelse af denne
|
WO2003022987A2
(fr)
|
2001-07-26 |
2003-03-20 |
Eos Biotechnology, Inc. |
Procedes de diagnostic de l'infection par l'hepatite c, compositions et procedes de criblage de modulateurs de l'infection par l'hepatite c
|
US6833441B2
(en)
|
2001-08-01 |
2004-12-21 |
Abmaxis, Inc. |
Compositions and methods for generating chimeric heteromultimers
|
US20040142325A1
(en)
|
2001-09-14 |
2004-07-22 |
Liat Mintz |
Methods and systems for annotating biomolecular sequences
|
ES2276735T3
(es)
|
2001-09-14 |
2007-07-01 |
Affimed Therapeutics Ag |
Anticuerpos fv multimericos de cadena sencilla en tandem.
|
EP2075256A2
(fr)
|
2002-01-14 |
2009-07-01 |
William Herman |
Ligands ciblés
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
AU2003227504A1
(en)
|
2002-04-15 |
2003-10-27 |
Chugai Seiyaku Kabushiki Kaisha |
METHOD OF CONSTRUCTING scDb LIBRARY
|
EP1354600A1
(fr)
|
2002-04-19 |
2003-10-22 |
Affimed Therapeutics AG |
Combinaison d'anticorps utilisable pour la thérapie de tumeurs
|
US20040018493A1
(en)
|
2002-07-12 |
2004-01-29 |
Anastasio Alison E. |
Haplotypes of the CD3E gene
|
JP4330532B2
(ja)
|
2002-07-18 |
2009-09-16 |
株式会社セルフリーサイエンス |
単鎖抗体およびその利用
|
CA2495389A1
(fr)
|
2002-08-19 |
2004-02-26 |
Genentech, Inc. |
Compositions et methodes de diagnostic et de traitement des tumeurs
|
US7820166B2
(en)
|
2002-10-11 |
2010-10-26 |
Micromet Ag |
Potent T cell modulating molecules
|
US9701754B1
(en)
|
2002-10-23 |
2017-07-11 |
City Of Hope |
Covalent disulfide-linked diabodies and uses thereof
|
AU2003304203A1
(en)
|
2002-10-29 |
2005-01-04 |
Pharmacia Corporation |
Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the same
|
AU2003283155A1
(en)
|
2002-11-14 |
2004-06-03 |
Adherex Technologies Inc. |
Compounds and methods for modulating functions of classical cadherins
|
EP1572116A4
(fr)
|
2002-11-26 |
2007-12-12 |
Genentech Inc |
Compositions et procedes destines au traitement de maladies de nature immune
|
JP2006524991A
(ja)
|
2003-05-08 |
2006-11-09 |
エクサイト セラピーズ インコーポレーティッド |
抗原特異的t細胞の作製および単離の方法
|
AU2004242845B2
(en)
|
2003-05-31 |
2011-06-02 |
Amgen Research (Munich) Gmbh |
Human-anti-human CD3 binding molecules
|
WO2004106381A1
(fr)
|
2003-05-31 |
2004-12-09 |
Micromet Ag |
Compositions pharmaceutiques comprenant des constructions d'anticorps anti-cd3, anti-cd19 bispecifiques pour le traitement de troubles associes aux lymphocytes b
|
JP2007537710A
(ja)
|
2003-06-11 |
2007-12-27 |
ワイス |
血小板糖タンパク質IBα改変体融合ポリペプチドおよびその使用法
|
US20050163782A1
(en)
|
2003-06-27 |
2005-07-28 |
Biogen Idec Ma Inc. |
Modified binding molecules comprising connecting peptides
|
JP5087274B2
(ja)
|
2003-06-30 |
2012-12-05 |
ドマンティス リミテッド |
ポリペプチド
|
US7754209B2
(en)
|
2003-07-26 |
2010-07-13 |
Trubion Pharmaceuticals |
Binding constructs and methods for use thereof
|
US20070037204A1
(en)
|
2003-08-08 |
2007-02-15 |
Hiroyuki ABURANTAI |
Gene overexpressed in cancer
|
WO2005019258A2
(fr)
|
2003-08-11 |
2005-03-03 |
Genentech, Inc. |
Compositions et methodes de traitement de maladies relatives au systeme immunitaire
|
WO2005028507A1
(fr)
|
2003-09-24 |
2005-03-31 |
Monash University |
Structure cristalline d'un complexe de cd3$g(e)$g(g)/okt3
|
US7235641B2
(en)
|
2003-12-22 |
2007-06-26 |
Micromet Ag |
Bispecific antibodies
|
ATE435238T1
(de)
|
2004-05-05 |
2009-07-15 |
Micromet Ag |
Herstellung eines einkettigen fv antikörperfragments
|
BRPI0511782B8
(pt)
|
2004-06-03 |
2021-05-25 |
Novimmune Sa |
anticorpos anti-cd3, uso e método de produção dos mesmos, composição farmacêutica, molécula de ácido nucleico isolada e vetor
|
JP2008512352A
(ja)
|
2004-07-17 |
2008-04-24 |
イムクローン システムズ インコーポレイティド |
新規な四価の二重特異性抗体
|
JP2008511337A
(ja)
|
2004-09-02 |
2008-04-17 |
ジェネンテック・インコーポレーテッド |
ヘテロ多量体分子
|
DE602006003695D1
(de)
|
2005-01-05 |
2009-01-02 |
F Star Biotech Forsch & Entw |
Synthetische Immunoglobulindomänen mit in Regionen des Moleküls, die sich von den die Komplementarität bestimmenden Bereichen unterscheiden, modifizierten Bindeeigenschaften
|
EP2295601A1
(fr)
|
2005-02-10 |
2011-03-16 |
Oncotherapy Science, Inc. |
Procédé de diagnostic de cancer de la vessie
|
US20120237442A1
(en)
|
2005-04-06 |
2012-09-20 |
Ibc Pharmaceuticals, Inc. |
Design and Construction of Novel Multivalent Antibodies
|
EP1868650B1
(fr)
|
2005-04-15 |
2018-10-03 |
MacroGenics, Inc. |
Di-anticorps covalents et leurs utilisations
|
US9284375B2
(en)
|
2005-04-15 |
2016-03-15 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
US9963510B2
(en)
|
2005-04-15 |
2018-05-08 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
GEP20115226B
(en)
|
2005-04-26 |
2011-06-10 |
Pfizer |
P-cadherin antibodies
|
WO2006116737A2
(fr)
|
2005-04-28 |
2006-11-02 |
Mcgill University |
Composes et methodes permettant de moduler les processus medies par la cadherine
|
CN101262885B
(zh)
|
2005-06-10 |
2015-04-01 |
中外制药株式会社 |
含有sc(Fv)2的药物组合物
|
JP2006345852A
(ja)
|
2005-06-16 |
2006-12-28 |
Virxsys Corp |
抗体複合体
|
UA92505C2
(ru)
|
2005-09-12 |
2010-11-10 |
Новиммюн С.А. |
Композиции на основе антитела против cd3
|
AU2006301492B2
(en)
|
2005-10-11 |
2011-06-09 |
Amgen Research (Munich) Gmbh |
Compositions comprising cross-species-specific antibodies and uses thereof
|
US8394926B2
(en)
|
2005-12-21 |
2013-03-12 |
Micromet Ag |
Pharmaceutical compositions with resistance to soluble CEA
|
WO2007075672A2
(fr)
|
2005-12-23 |
2007-07-05 |
Lankenau Institute For Medical Research |
Marqueurs pour le pronostic du cancer
|
CN101432303A
(zh)
|
2006-02-28 |
2009-05-13 |
肿瘤疗法科学股份有限公司 |
利用抗cdh3抗体的效应物功能来损伤细胞的方法
|
WO2007106507A2
(fr)
|
2006-03-14 |
2007-09-20 |
Petrie Howard T |
Détection de l'expression génique dans un échantillon ou un tissu mixte
|
NZ591252A
(en)
|
2006-03-17 |
2012-06-29 |
Biogen Idec Inc |
Methods of designing antibody or antigen binding fragments thereof with substituted non-covarying amino acids
|
PT1999154E
(pt)
|
2006-03-24 |
2013-01-24 |
Merck Patent Gmbh |
Domínios proteicos heterodiméricos modificados
|
US8535677B2
(en)
|
2006-06-06 |
2013-09-17 |
Oxford Biotherapeutics, Ltd. |
Antibody drug conjugate treatment of colorectal cancer
|
TWI610939B
(zh)
|
2007-02-21 |
2018-01-11 |
腫瘤療法 科學股份有限公司 |
表現腫瘤相關抗原之癌症的胜肽疫苗
|
PT2520590T
(pt)
|
2007-04-03 |
2018-11-14 |
Amgen Res Munich Gmbh |
Domínio de ligação específico de espécies cruzadas
|
RS53008B2
(sr)
*
|
2007-04-03 |
2022-12-30 |
Amgen Res Munich Gmbh |
Interspecijski specifičan cd3-epsilon vezujući domen
|
WO2008124858A2
(fr)
|
2007-04-11 |
2008-10-23 |
F-Star Biotechnologische Forschungs- Und Entwicklungsges. M.B.H. |
Récepteur ciblé
|
US8263064B2
(en)
|
2007-06-04 |
2012-09-11 |
Rappaport Family Institute For Research In The Medical Sciences |
Method of suppressing disease severity of multiple sclerosis using chemokine CXC11
|
CN101952312A
(zh)
|
2007-07-31 |
2011-01-19 |
米迪缪尼有限公司 |
多特异性表位结合蛋白及其应用
|
EP2178914A2
(fr)
|
2007-08-15 |
2010-04-28 |
Bayer Schering Pharma Aktiengesellschaft |
Anticorps monospécifiques et multispécifiques, et procédés d'utilisation
|
CN104356225B
(zh)
|
2007-08-20 |
2018-02-13 |
肿瘤疗法科学股份有限公司 |
Cdh3 肽以及含有cdh3 肽的药剂
|
ES2622460T3
(es)
|
2007-09-26 |
2017-07-06 |
Ucb Biopharma Sprl |
Fusiones de anticuerpos con doble especificidad
|
US20100310451A1
(en)
|
2007-11-01 |
2010-12-09 |
The Royal Institution For The Advancement Of Learn |
Altered n-cadherin processing in tumor cells by furin and proprotein convertase 5a (pc5a)
|
KR101710472B1
(ko)
|
2007-11-30 |
2017-02-27 |
글락소 그룹 리미티드 |
항원-결합 작제물
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
US8227577B2
(en)
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
EP2080812A1
(fr)
|
2008-01-18 |
2009-07-22 |
Transmedi SA |
Compositions et procédés pour détecter des peptides post-stop
|
US9029508B2
(en)
|
2008-04-29 |
2015-05-12 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
WO2010001585A1
(fr)
|
2008-06-30 |
2010-01-07 |
Oncotherapy Science, Inc. |
Anticorps anti-cdh3 marqués par un marqueur radioisotopique, et leurs utilisations
|
TW201008574A
(en)
|
2008-08-19 |
2010-03-01 |
Oncotherapy Science Inc |
INHBB epitope peptides and vaccines containing the same
|
EP2352763B2
(fr)
|
2008-10-01 |
2022-09-21 |
Amgen Research (Munich) GmbH |
Anticorps monocaténaires bispécifiques spécifiques d'antigènes cibles de masse moléculaire élevée
|
EP2352765B1
(fr)
|
2008-10-01 |
2018-01-03 |
Amgen Research (Munich) GmbH |
Anticorps monocaténaire bispécifique à domaine unique, spécifique d'espèces croisées
|
EP2370467B1
(fr)
|
2008-10-01 |
2016-09-07 |
Amgen Research (Munich) GmbH |
Anticorps monocaténaire bispécifique pscaxcd3 (cd19xcd3, c-metxcd3, endosialinxcd3, epcamxc d3, igf-1rxcd3 ou fapalpha xcd3), spécifique d'espèces croisées
|
CA2738565C
(fr)
|
2008-10-01 |
2023-10-10 |
Micromet Ag |
Anticorps monocatenaire bispecifique psmaxcd3, specifique d'especes croisees
|
WO2010040545A1
(fr)
|
2008-10-06 |
2010-04-15 |
Novoplant Gmbh |
Formats d’anticorps stables à la protéolyse
|
SG172754A1
(en)
|
2008-10-10 |
2011-08-29 |
Trubion Pharmaceuticals Inc |
Tcr complex immunotherapeutics
|
US20110020221A1
(en)
|
2009-04-09 |
2011-01-27 |
The Johns Hopkins University |
Cancer stem cell expression patterns and compounds to target cancer stem cells
|
KR20120051603A
(ko)
|
2009-05-01 |
2012-05-22 |
고쿠리츠다이가쿠호징 도쿄다이가쿠 |
항카드헤린 항체
|
EP2435473B1
(fr)
|
2009-05-27 |
2013-10-02 |
F.Hoffmann-La Roche Ag |
Anticorps tri ou tétra-spécifiques
|
US8703132B2
(en)
|
2009-06-18 |
2014-04-22 |
Hoffmann-La Roche, Inc. |
Bispecific, tetravalent antigen binding proteins
|
NZ598929A
(en)
|
2009-09-01 |
2014-05-30 |
Abbvie Inc |
Dual variable domain immunoglobulins and uses thereof
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
WO2011031833A2
(fr)
|
2009-09-09 |
2011-03-17 |
Theraclone Sciences, Inc. |
Anticorps anticancéreux pour humains
|
ES2667258T3
(es)
|
2009-09-10 |
2018-05-10 |
Ucb Biopharma Sprl |
Anticuerpos multivalentes
|
US9885711B2
(en)
|
2009-09-25 |
2018-02-06 |
Xoma Technology Ltd. |
Screening methods
|
JP2013508392A
(ja)
|
2009-10-20 |
2013-03-07 |
グラクソ グループ リミテッド |
自己免疫疾患における抗cd3抗体の投薬
|
US20120316071A1
(en)
|
2009-11-04 |
2012-12-13 |
Vaughn Smider |
Methods for affinity maturation-based antibody optimization
|
GB0920127D0
(en)
|
2009-11-17 |
2009-12-30 |
Ucb Pharma Sa |
Antibodies
|
WO2011071541A2
(fr)
|
2009-12-11 |
2011-06-16 |
The Scripps Research Institute |
Agents modulateurs de cadhérines
|
WO2011076781A1
(fr)
|
2009-12-22 |
2011-06-30 |
Novartis Ag |
Protéine hybride tétravalente à région constante d'anticorps anti-cd-47 à utiliser en thérapie
|
US20110165161A1
(en)
|
2009-12-23 |
2011-07-07 |
Shih-Yao Lin |
Anti-epcam antibodies that induce apoptosis of cancer cells and methods using same
|
EP3450459B1
(fr)
|
2009-12-28 |
2021-05-26 |
OncoTherapy Science, Inc. |
Anticorps anti-cdh3 et leurs utilisations
|
CN102014475B
(zh)
|
2010-01-08 |
2012-01-04 |
华为技术有限公司 |
资源映射、码分复用方法及装置
|
WO2011085178A1
(fr)
|
2010-01-11 |
2011-07-14 |
Trustees Of Dartmouth College |
Protéine de fusion monomérique bispécifique
|
JP5380553B2
(ja)
|
2010-02-10 |
2014-01-08 |
富士フイルムRiファーマ株式会社 |
放射性金属標識抗カドヘリン抗体
|
PT2361936T
(pt)
|
2010-02-25 |
2016-07-15 |
Affimed Gmbh |
Molécula que se liga a antigénio e utilizações desta
|
WO2011109588A1
(fr)
|
2010-03-03 |
2011-09-09 |
Health Research Inc. |
Nouveaux immunogènes et anticorps cd3 epsilon
|
TWI653333B
(zh)
|
2010-04-01 |
2019-03-11 |
安進研究(慕尼黑)有限責任公司 |
跨物種專一性之PSMAxCD3雙專一性單鏈抗體
|
PE20130460A1
(es)
|
2010-05-03 |
2013-04-26 |
Genentech Inc |
Composiciones y metodos para el diagnostico y tratamiento de tumores
|
MX339622B
(es)
*
|
2010-08-02 |
2016-06-02 |
Macrogenics Inc |
Diacuerpos covalentes y sus usos.
|
JP2013535508A
(ja)
|
2010-08-13 |
2013-09-12 |
ベイラー リサーチ インスティテュート |
抗体付きアジュバントを抗原提示細胞に直接的に標的化することをベースにした新規ワクチンアジュバント
|
MX358739B
(es)
|
2010-08-14 |
2018-09-03 |
Abbvie Inc Star |
Proteinas de union a amiloide beta.
|
PT2606064E
(pt)
|
2010-08-16 |
2015-06-08 |
Novimmune Sa |
Processos para a geração de anticorpos poliespecíficos e polivalentes
|
AU2011312106B8
(en)
|
2010-10-08 |
2017-09-14 |
City Of Hope |
A monoclonal antibody framework binding interface for meditopes, meditope delivery systems and methods for their use
|
JP2014015396A
(ja)
|
2010-10-29 |
2014-01-30 |
Perseus Proteomics Inc |
高い親和性を有する抗cdh3抗体
|
EP3708586A1
(fr)
|
2010-10-29 |
2020-09-16 |
Perseus Proteomics Inc. |
Anticorps anti-cdh3 ayant une forte capacité d'internalisation
|
CN103429737B
(zh)
|
2010-11-30 |
2020-07-14 |
中外制药株式会社 |
细胞毒诱导治疗剂
|
WO2012088290A2
(fr)
|
2010-12-22 |
2012-06-28 |
Abbott Laboratories |
Protéines de liaison à trois domaines variables et leurs utilisations
|
WO2012088302A2
(fr)
|
2010-12-22 |
2012-06-28 |
Abbott Laboratories |
Protéines de liaison à une demi-immunoglobuline et leurs utilisations
|
US10689447B2
(en)
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
TW201247706A
(en)
|
2011-03-08 |
2012-12-01 |
Baylor Res Inst |
Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells
|
WO2012122528A1
(fr)
|
2011-03-10 |
2012-09-13 |
Hco Antibody, Inc. |
Molécules de type anticorps tricaténaires bispécifiques
|
CA2830254C
(fr)
|
2011-03-16 |
2019-09-10 |
Amgen Inc. |
Variants de fc
|
EP3138581B1
(fr)
|
2011-03-17 |
2019-01-02 |
The University of Birmingham |
Immunothérapie redirigée
|
MX342135B
(es)
|
2011-03-17 |
2016-09-14 |
Ramot At Tel-Aviv Univ Ltd |
Anticuerpos asimetricos, biespecificos y monoespecificos, y metodos para generar los mismos.
|
CA2830987A1
(fr)
|
2011-03-22 |
2012-09-27 |
Baylor Research Institute |
Ciblage de cellules dendritiques (cd) pour le vaccin de la tuberculose (tb)
|
US20120301465A1
(en)
|
2011-03-25 |
2012-11-29 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Compositions and methods to immunize against hepatitis c virus
|
TWI588156B
(zh)
|
2011-03-28 |
2017-06-21 |
賽諾菲公司 |
具有交叉結合區定向之雙重可變區類抗體結合蛋白
|
EP3536708A1
(fr)
|
2011-04-19 |
2019-09-11 |
Pfizer Inc |
Combinaisons d'anticorps anti-4-1bb et d'anticorps induisant une cytotoxicité à médiation cellulaire dépendante d'un anticorps (adcc) pour le traitement du cancer
|
US20140161800A1
(en)
|
2011-04-22 |
2014-06-12 |
John W. Blankenship |
Prostate-Specific Membrane Antigen Binding Proteins and Related Compositions and Methods
|
CN103842383B
(zh)
|
2011-05-16 |
2017-11-03 |
健能隆医药技术(上海)有限公司 |
多特异性fab融合蛋白及其使用方法
|
JP6145088B2
(ja)
|
2011-05-21 |
2017-06-07 |
マクロジェニクス,インコーポレーテッド |
脱免疫化血清結合ドメイン及び血清半減期を延長するためのその使用
|
ME03440B
(fr)
|
2011-05-21 |
2020-01-20 |
Macrogenics Inc |
Molécules de liaison des cd3 capables de se lier aux cd3 humaines et non humaines
|
CN106432506A
(zh)
|
2011-05-24 |
2017-02-22 |
泽恩格尼亚股份有限公司 |
多价和单价多特异性复合物及其用途
|
WO2012162583A1
(fr)
|
2011-05-26 |
2012-11-29 |
Ibc Pharmaceuticals, Inc. |
Conception et construction de nouveaux anticorps multivalents
|
JP2014516542A
(ja)
|
2011-05-27 |
2014-07-17 |
デュタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング |
二重標的化
|
BR112013031762A2
(pt)
|
2011-06-16 |
2016-09-13 |
Novartis Ag |
proteínas solúveis para utilização como terapêuticos
|
JPWO2012176765A1
(ja)
|
2011-06-24 |
2015-02-23 |
株式会社ペルセウスプロテオミクス |
抗ヒトp−カドへリン(cdh3)遺伝子組み換え抗体
|
WO2013012414A1
(fr)
|
2011-07-18 |
2013-01-24 |
Medimmune, Llc |
Régimes posologiques pour le traitement cancers exprimant cea
|
JP5938473B2
(ja)
|
2011-07-22 |
2016-06-22 |
アフィメート テラポイティクス アーゲー |
多価抗原結合Fv分子
|
PL2748202T3
(pl)
|
2011-08-23 |
2018-12-31 |
Roche Glycart Ag |
Dwuswoiste cząsteczki wiążące antygen
|
CN107586340B
(zh)
|
2011-08-23 |
2022-01-21 |
罗切格利卡特公司 |
对t细胞活化性抗原和肿瘤抗原特异性的双特异性抗体及使用方法
|
CA2837975C
(fr)
|
2011-08-23 |
2022-04-05 |
Roche Glycart Ag |
Molecules bispecifiques de liaison a l'antigene activant les lymphocytes t.
|
BR112014004166A2
(pt)
|
2011-08-23 |
2018-05-29 |
Roche Glycart Ag |
anticorpo biespecífico compreendendo pelo menos dois fragmentos fab, célula hospedeira procariótica ou eucariótica, metodo de produção de um anticorpo, imunoconjugado e invenção
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
WO2013041865A1
(fr)
|
2011-09-22 |
2013-03-28 |
Immunocore Limited |
Récepteurs de lymphocytes t
|
EP2758438A1
(fr)
|
2011-09-23 |
2014-07-30 |
Amgen Research (Munich) GmbH |
Molécules de liaison bispécifiques pour 5t4 et cd3
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
CN104203981A
(zh)
|
2011-12-19 |
2014-12-10 |
合成免疫股份有限公司 |
双特异性抗体分子
|
GB201203442D0
(en)
|
2012-02-28 |
2012-04-11 |
Univ Birmingham |
Immunotherapeutic molecules and uses
|
WO2013128027A1
(fr)
|
2012-03-01 |
2013-09-06 |
Amgen Research (Munich) Gmbh |
Molécules de liaison à un polypeptide à longue durée de vie
|
CN104220595A
(zh)
|
2012-04-04 |
2014-12-17 |
株式会社英仙蛋白质科学 |
抗cdh3(p-钙粘着蛋白)抗体的药剂偶联物
|
CA2870545A1
(fr)
|
2012-04-20 |
2013-10-24 |
Emergent Product Development Seattle, Llc |
Polypeptides se liant a cd3
|
EA039663B1
(ru)
*
|
2012-05-03 |
2022-02-24 |
Амген Инк. |
Применение антитела против pcsk9 для снижения сывороточного холестерина лпнп и лечения связанных с холестерином расстройств
|
US10647756B2
(en)
*
|
2015-05-18 |
2020-05-12 |
Pfizer Inc. |
Humanized antibodies
|