SG11201507275TA - Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions - Google Patents
Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditionsInfo
- Publication number
- SG11201507275TA SG11201507275TA SG11201507275TA SG11201507275TA SG11201507275TA SG 11201507275T A SG11201507275T A SG 11201507275TA SG 11201507275T A SG11201507275T A SG 11201507275TA SG 11201507275T A SG11201507275T A SG 11201507275TA SG 11201507275T A SG11201507275T A SG 11201507275TA
- Authority
- SG
- Singapore
- Prior art keywords
- materials
- methods
- stem cells
- pluripotent stem
- cells under
- Prior art date
Links
- 230000004069 differentiation Effects 0.000 title 1
- 210000001778 pluripotent stem cell Anatomy 0.000 title 1
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0056—Xeno-free medium
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
- C12N5/0695—Stem cells; Progenitor cells; Precursor cells
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/02—Atmosphere, e.g. low oxygen conditions
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/165—Vascular endothelial growth factor [VEGF]
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1394—Bone marrow stromal cells; whole marrow
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Developmental Biology & Embryology (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361779564P | 2013-03-13 | 2013-03-13 | |
PCT/US2014/024518 WO2014165131A1 (en) | 2013-03-13 | 2014-03-12 | Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions |
Publications (1)
Publication Number | Publication Date |
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SG11201507275TA true SG11201507275TA (en) | 2015-10-29 |
Family
ID=50678273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507275TA SG11201507275TA (en) | 2013-03-13 | 2014-03-12 | Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions |
Country Status (19)
Country | Link |
---|---|
US (3) | US9938499B2 (zh) |
EP (1) | EP2970912B1 (zh) |
JP (1) | JP6677631B2 (zh) |
KR (1) | KR102151210B1 (zh) |
CN (1) | CN105209609B (zh) |
AU (1) | AU2014248651B2 (zh) |
BR (1) | BR112015022770B1 (zh) |
CA (2) | CA2905786C (zh) |
DK (1) | DK2970912T3 (zh) |
ES (1) | ES2720196T3 (zh) |
HK (1) | HK1218927A1 (zh) |
HU (1) | HUE043785T2 (zh) |
IL (1) | IL241286B (zh) |
MX (1) | MX366900B (zh) |
PL (1) | PL2970912T3 (zh) |
PT (1) | PT2970912T (zh) |
SG (1) | SG11201507275TA (zh) |
TR (1) | TR201904270T4 (zh) |
WO (1) | WO2014165131A1 (zh) |
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WO2011140441A2 (en) | 2010-05-06 | 2011-11-10 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
US9868939B2 (en) | 2013-06-12 | 2018-01-16 | Wisconsin Alumni Research Foundation | Generating vasculogenic cell populations |
AU2015267148B2 (en) | 2014-05-28 | 2021-07-29 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
AU2015331848B2 (en) | 2014-10-17 | 2022-03-03 | Children's Hospital Medical Center, D/B/A Cincinnati Children's Hospital Medical Center | In vivo model of human small intestine using pluripotent stem cells and methods of making and using same |
US11220672B2 (en) * | 2014-12-31 | 2022-01-11 | Wisconsin Alumni Research Foundation | Human pluripotent stem cell-based system for generating endothelial cells |
JP6800859B2 (ja) * | 2015-01-26 | 2020-12-16 | フェイト セラピューティクス,インコーポレイテッド | 造血細胞分化を誘導するための方法および組成物 |
SG11201706706XA (en) | 2015-02-20 | 2017-09-28 | Wisconsin Alumni Res Found | Generating arterial endothelial cell populations |
WO2016141084A1 (en) * | 2015-03-03 | 2016-09-09 | The Board Of Trustees Of The Leland Stanford Junior University | Producing mesodermal cell types and methods of using the same |
CN104660703B (zh) * | 2015-03-05 | 2017-12-15 | 国家电网公司 | 多网络融合用电信息采集系统及最优通信网络的选择方法 |
US10836997B2 (en) * | 2015-03-09 | 2020-11-17 | Keio University | Method for differentiating pluripotent stem cells into desired cell type |
EP3313434A4 (en) * | 2015-06-29 | 2019-03-27 | Northeastern University | GENERATOR OF DENDRITIC CELLS |
JP6646311B2 (ja) * | 2015-07-17 | 2020-02-14 | 国立大学法人京都大学 | 多能性幹細胞から中胚葉前駆細胞および血液血管前駆細胞への分化誘導法 |
JP6976939B2 (ja) * | 2015-10-20 | 2021-12-08 | フジフィルム セルラー ダイナミクス,インコーポレイテッド | 遺伝的プログラミングによる多系統造血前駆細胞の作製 |
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BRPI0912517A2 (pt) * | 2008-05-06 | 2019-09-24 | Advanced Cell Tech Inc | métodos para a produção de células eritroides anucleadas dericadas de células-tronco pluripotentes |
WO2010099539A1 (en) | 2009-02-27 | 2010-09-02 | Cellular Dynamics International, Inc. | Differentiation of pluripotent cells |
JPWO2010143529A1 (ja) * | 2009-06-09 | 2012-11-22 | 国立大学法人名古屋大学 | 多能性幹細胞を胸腺上皮へ分化誘導する方法 |
US9234170B2 (en) * | 2010-04-25 | 2016-01-12 | Mount Sinai School Of Medicine | Generation of anterior foregut endoderm from pluripotent cells |
US9279107B2 (en) | 2010-08-05 | 2016-03-08 | Wisconsin Alumni Research Foundation | Simplified basic media for human pluripotent cell culture |
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2014
- 2014-03-12 AU AU2014248651A patent/AU2014248651B2/en active Active
- 2014-03-12 DK DK14722013.1T patent/DK2970912T3/en active
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JP2016512031A (ja) | 2016-04-25 |
IL241286A0 (en) | 2015-11-30 |
CA2905786A1 (en) | 2014-10-09 |
TR201904270T4 (tr) | 2019-05-21 |
US20220228118A1 (en) | 2022-07-21 |
BR112015022770B1 (pt) | 2022-11-16 |
KR102151210B1 (ko) | 2020-09-02 |
PL2970912T3 (pl) | 2019-08-30 |
CN105209609B (zh) | 2020-08-21 |
IL241286B (en) | 2020-03-31 |
US9938499B2 (en) | 2018-04-10 |
AU2014248651A1 (en) | 2015-10-01 |
ES2720196T3 (es) | 2019-07-18 |
HK1218927A1 (zh) | 2017-03-17 |
WO2014165131A1 (en) | 2014-10-09 |
MX366900B (es) | 2019-07-30 |
US20180258398A1 (en) | 2018-09-13 |
KR20150126943A (ko) | 2015-11-13 |
BR112015022770A8 (pt) | 2019-11-26 |
MX2015012202A (es) | 2015-11-30 |
HUE043785T2 (hu) | 2019-09-30 |
PT2970912T (pt) | 2019-05-31 |
US20140273211A1 (en) | 2014-09-18 |
JP6677631B2 (ja) | 2020-04-08 |
AU2014248651B2 (en) | 2019-01-17 |
CA3141731A1 (en) | 2014-10-09 |
CA2905786C (en) | 2022-01-25 |
EP2970912A1 (en) | 2016-01-20 |
DK2970912T3 (en) | 2019-04-23 |
EP2970912B1 (en) | 2019-03-06 |
BR112015022770A2 (pt) | 2017-07-18 |
CN105209609A (zh) | 2015-12-30 |
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