SG11201502795VA - Novel process for making compounds for use in the treatment of cancer - Google Patents

Novel process for making compounds for use in the treatment of cancer

Info

Publication number
SG11201502795VA
SG11201502795VA SG11201502795VA SG11201502795VA SG11201502795VA SG 11201502795V A SG11201502795V A SG 11201502795VA SG 11201502795V A SG11201502795V A SG 11201502795VA SG 11201502795V A SG11201502795V A SG 11201502795VA SG 11201502795V A SG11201502795V A SG 11201502795VA
Authority
SG
Singapore
Prior art keywords
cancer
treatment
novel process
making compounds
compounds
Prior art date
Application number
SG11201502795VA
Other languages
English (en)
Inventor
Sriram Naganathan
Nathan Guz
Matthew Pfeiffer
C Gregory Sowell
Tracy Bostick
Jason Yang
Amit Srivastava
Original Assignee
Exelixis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exelixis Inc filed Critical Exelixis Inc
Publication of SG11201502795VA publication Critical patent/SG11201502795VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
SG11201502795VA 2012-10-12 2013-10-14 Novel process for making compounds for use in the treatment of cancer SG11201502795VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261713104P 2012-10-12 2012-10-12
PCT/US2013/064866 WO2014059422A1 (en) 2012-10-12 2013-10-14 Novel process for making compounds for use in the treatment of cancer

Publications (1)

Publication Number Publication Date
SG11201502795VA true SG11201502795VA (en) 2015-05-28

Family

ID=49474740

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201502795VA SG11201502795VA (en) 2012-10-12 2013-10-14 Novel process for making compounds for use in the treatment of cancer

Country Status (31)

Country Link
US (4) US9771347B2 (enrdf_load_stackoverflow)
EP (1) EP2909188B1 (enrdf_load_stackoverflow)
JP (2) JP6300042B2 (enrdf_load_stackoverflow)
KR (1) KR102204520B1 (enrdf_load_stackoverflow)
CN (2) CN104837826B (enrdf_load_stackoverflow)
AU (1) AU2013328929B2 (enrdf_load_stackoverflow)
BR (1) BR112015008113B1 (enrdf_load_stackoverflow)
CA (1) CA2889466C (enrdf_load_stackoverflow)
CL (1) CL2015000926A1 (enrdf_load_stackoverflow)
CR (2) CR20200237A (enrdf_load_stackoverflow)
EA (1) EA030613B1 (enrdf_load_stackoverflow)
ES (1) ES2671502T3 (enrdf_load_stackoverflow)
GE (1) GEP201706690B (enrdf_load_stackoverflow)
HK (1) HK1213567A1 (enrdf_load_stackoverflow)
HR (1) HRP20180670T1 (enrdf_load_stackoverflow)
IL (1) IL238116B (enrdf_load_stackoverflow)
IN (1) IN2015DN03928A (enrdf_load_stackoverflow)
MA (1) MA38085B1 (enrdf_load_stackoverflow)
MX (2) MX372708B (enrdf_load_stackoverflow)
MY (1) MY186549A (enrdf_load_stackoverflow)
NZ (1) NZ706723A (enrdf_load_stackoverflow)
PE (3) PE20151494A1 (enrdf_load_stackoverflow)
PH (1) PH12015500785A1 (enrdf_load_stackoverflow)
PL (1) PL2909188T3 (enrdf_load_stackoverflow)
SA (1) SA515360271B1 (enrdf_load_stackoverflow)
SG (1) SG11201502795VA (enrdf_load_stackoverflow)
SI (1) SI2909188T1 (enrdf_load_stackoverflow)
TR (1) TR201807861T4 (enrdf_load_stackoverflow)
UA (1) UA115455C2 (enrdf_load_stackoverflow)
WO (1) WO2014059422A1 (enrdf_load_stackoverflow)
ZA (1) ZA201502349B (enrdf_load_stackoverflow)

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CN105330643B (zh) * 2015-12-09 2017-12-05 苏州明锐医药科技有限公司 卡比替尼的制备方法
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BR112019002036A2 (pt) 2016-08-12 2019-05-14 Genentech Inc métodos de tratamento de um sujeito com câncer colorretal, kit para tratamento do câncer colorretal em um sujeito humano e combinação de fármacos para a terapia do câncer colorretal
JP2019534251A (ja) 2016-09-29 2019-11-28 ジェネンテック, インコーポレイテッド Mek阻害剤、pd−1軸阻害剤、及びタキサンを用いた併用療法
WO2020187674A1 (en) 2019-03-15 2020-09-24 Sandoz Ag Crystalline (s)-[3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl][3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl]methanone hemisuccinate
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EP4319749A1 (en) 2021-04-06 2024-02-14 Genentech, Inc. Combination therapy with belvarafenib and cobimetinib or with belvarafenib, cobimetinib, and atezolizumab

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Also Published As

Publication number Publication date
JP2018052973A (ja) 2018-04-05
PE20200387A1 (es) 2020-02-24
US11414396B2 (en) 2022-08-16
EP2909188B1 (en) 2018-03-07
US10239858B2 (en) 2019-03-26
SI2909188T1 (en) 2018-07-31
EA030613B1 (ru) 2018-08-31
BR112015008113B1 (pt) 2022-05-24
MX2020005533A (es) 2020-10-12
CN104837826B (zh) 2018-07-27
JP6300042B2 (ja) 2018-03-28
US20200392104A1 (en) 2020-12-17
PE20151494A1 (es) 2015-11-06
WO2014059422A1 (en) 2014-04-17
IN2015DN03928A (enrdf_load_stackoverflow) 2015-10-02
PH12015500785B1 (en) 2015-06-15
US9771347B2 (en) 2017-09-26
PH12015500785A1 (en) 2015-06-15
EP2909188A1 (en) 2015-08-26
JP2015533175A (ja) 2015-11-19
US10793541B2 (en) 2020-10-06
BR112015008113A2 (pt) 2017-07-04
MX372708B (es) 2020-05-29
KR20150067339A (ko) 2015-06-17
SA515360271B1 (ar) 2016-05-19
CN108948043A (zh) 2018-12-07
MA38085A1 (fr) 2018-08-31
PE20191818A1 (es) 2019-12-27
CR20150245A (es) 2015-11-19
ZA201502349B (en) 2019-12-18
AU2013328929A1 (en) 2015-04-30
ES2671502T3 (es) 2018-06-06
KR102204520B1 (ko) 2021-01-20
CA2889466C (en) 2021-09-14
US20190185447A1 (en) 2019-06-20
MX2015004660A (es) 2015-08-07
US20170349569A1 (en) 2017-12-07
GEP201706690B (en) 2017-06-26
CL2015000926A1 (es) 2015-08-28
TR201807861T4 (tr) 2018-06-21
CR20200237A (es) 2020-07-26
MA38085B1 (fr) 2018-11-30
UA115455C2 (uk) 2017-11-10
HK1213878A1 (en) 2016-07-15
HRP20180670T1 (hr) 2018-07-13
MY186549A (en) 2021-07-26
CN104837826A (zh) 2015-08-12
AU2013328929B2 (en) 2018-01-04
US20150210668A1 (en) 2015-07-30
IL238116B (en) 2018-06-28
EA201590700A1 (ru) 2015-09-30
CN108948043B (zh) 2021-05-04
HK1213567A1 (zh) 2016-07-08
CA2889466A1 (en) 2014-04-17
NZ706723A (en) 2018-07-27
PL2909188T3 (pl) 2018-08-31

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