PL2855475T3 - Alfa-karboliny do leczenia nowotworu - Google Patents

Alfa-karboliny do leczenia nowotworu

Info

Publication number
PL2855475T3
PL2855475T3 PL13726442T PL13726442T PL2855475T3 PL 2855475 T3 PL2855475 T3 PL 2855475T3 PL 13726442 T PL13726442 T PL 13726442T PL 13726442 T PL13726442 T PL 13726442T PL 2855475 T3 PL2855475 T3 PL 2855475T3
Authority
PL
Poland
Prior art keywords
carbolines
cancer
alpha
treatment
Prior art date
Application number
PL13726442T
Other languages
English (en)
Inventor
Carlo Gambacorti-Passerini
Luca Mologni
Leonardo Scapozza
William Bisson
Shaheen Ahmed
Peter Goekjian
Sébastien Tardy
Alexandre Orsato
David Gueyrard
Joseph Benoit
Original Assignee
Università Degli Studi Di Milano - Bicocca
Université De Genève
Université Claude Bernard Lyon 1
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Università Degli Studi Di Milano - Bicocca, Université De Genève, Université Claude Bernard Lyon 1 filed Critical Università Degli Studi Di Milano - Bicocca
Publication of PL2855475T3 publication Critical patent/PL2855475T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL13726442T 2012-05-11 2013-05-10 Alfa-karboliny do leczenia nowotworu PL2855475T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20120167755 EP2662372A1 (en) 2012-05-11 2012-05-11 Alpha-carbolines for the treatment of cancer
EP13726442.0A EP2855475B1 (en) 2012-05-11 2013-05-10 Alpha-carbolines for the treatment of cancer
PCT/EP2013/059721 WO2013167730A1 (en) 2012-05-11 2013-05-10 Alpha-carbolines for the treatment of cancer

Publications (1)

Publication Number Publication Date
PL2855475T3 true PL2855475T3 (pl) 2018-02-28

Family

ID=48570067

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13726442T PL2855475T3 (pl) 2012-05-11 2013-05-10 Alfa-karboliny do leczenia nowotworu

Country Status (7)

Country Link
US (1) US9428500B2 (pl)
EP (2) EP2662372A1 (pl)
CN (1) CN104540823B (pl)
CA (1) CA2872948A1 (pl)
ES (1) ES2641816T3 (pl)
PL (1) PL2855475T3 (pl)
WO (1) WO2013167730A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013010603A1 (de) * 2013-06-26 2014-12-31 Martin-Luther-Universität Halle-Wittenberg, Körperschaft des öffentlichen Rechts Brustkrebszellwachstum-hemmende Enzyminhibitoren, Verfahren zu ihrer Herstellung sowie deren Verwendung
WO2019016071A1 (en) 2017-07-18 2019-01-24 Bayer Pharma Aktiengesellschaft SUBSTITUTED PYRROLOPYRIDINE DERIVATIVES
CN112574176B (zh) * 2019-09-27 2024-03-15 隆泰申医药科技(南京)有限公司 一种杂芳基类化合物及其应用
WO2021119834A1 (en) * 2019-12-18 2021-06-24 Universite De Montreal Modulators of cullin 3 adaptor kbtbd4 as anti-cancer compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2876377B1 (fr) * 2004-10-11 2007-03-16 Univ Claude Bernard Lyon Nouveaux derives de 9h-pyrido[2,3-b]indole, leur procede de preparation, ainsi que les compositions pharmaceutiques contenant de tels composes
CA2610347A1 (en) * 2005-06-09 2006-06-08 Boehringer Ingelheim International Gmbh Alpha-carbolines as cdk-1 inhibitors
EP2161271A1 (en) 2008-09-08 2010-03-10 Università Degli Studi Di Milano - Bicocca Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl

Also Published As

Publication number Publication date
CA2872948A1 (en) 2013-11-14
US20150105554A1 (en) 2015-04-16
US9428500B2 (en) 2016-08-30
EP2855475A1 (en) 2015-04-08
WO2013167730A1 (en) 2013-11-14
ES2641816T3 (es) 2017-11-14
CN104540823A (zh) 2015-04-22
CN104540823B (zh) 2017-02-22
EP2855475B1 (en) 2017-06-28
EP2662372A1 (en) 2013-11-13

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