SG11201500234YA - Process for making isoquinoline compounds - Google Patents

Process for making isoquinoline compounds

Info

Publication number
SG11201500234YA
SG11201500234YA SG11201500234YA SG11201500234YA SG11201500234YA SG 11201500234Y A SG11201500234Y A SG 11201500234YA SG 11201500234Y A SG11201500234Y A SG 11201500234YA SG 11201500234Y A SG11201500234Y A SG 11201500234YA SG 11201500234Y A SG11201500234Y A SG 11201500234YA
Authority
SG
Singapore
Prior art keywords
isoquinoline compounds
making
making isoquinoline
compounds
isoquinoline
Prior art date
Application number
SG11201500234YA
Other languages
English (en)
Inventor
Michael D Thompson
Jung Min Park
Michael P Arend
Original Assignee
Fibrogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fibrogen Inc filed Critical Fibrogen Inc
Publication of SG11201500234YA publication Critical patent/SG11201500234YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epidemiology (AREA)
SG11201500234YA 2012-07-16 2013-07-15 Process for making isoquinoline compounds SG11201500234YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261672191P 2012-07-16 2012-07-16
PCT/US2013/050538 WO2014014834A1 (en) 2012-07-16 2013-07-15 Process for making isoquinoline compounds

Publications (1)

Publication Number Publication Date
SG11201500234YA true SG11201500234YA (en) 2015-02-27

Family

ID=48857024

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201500234YA SG11201500234YA (en) 2012-07-16 2013-07-15 Process for making isoquinoline compounds

Country Status (22)

Country Link
US (2) US9340511B2 (enrdf_load_stackoverflow)
EP (2) EP3219706A1 (enrdf_load_stackoverflow)
JP (1) JP6196671B2 (enrdf_load_stackoverflow)
KR (1) KR102145272B1 (enrdf_load_stackoverflow)
CN (2) CN106083719B (enrdf_load_stackoverflow)
AU (1) AU2013290437B2 (enrdf_load_stackoverflow)
BR (1) BR112015001106B1 (enrdf_load_stackoverflow)
CA (1) CA2879238C (enrdf_load_stackoverflow)
CY (1) CY2022018I1 (enrdf_load_stackoverflow)
DK (1) DK2872487T3 (enrdf_load_stackoverflow)
ES (1) ES2631655T3 (enrdf_load_stackoverflow)
HU (2) HUE034409T2 (enrdf_load_stackoverflow)
IL (1) IL236625B (enrdf_load_stackoverflow)
IN (1) IN2015KN00265A (enrdf_load_stackoverflow)
MX (1) MX350922B (enrdf_load_stackoverflow)
MY (1) MY171483A (enrdf_load_stackoverflow)
NZ (1) NZ704660A (enrdf_load_stackoverflow)
PL (1) PL2872487T3 (enrdf_load_stackoverflow)
PT (1) PT2872487T (enrdf_load_stackoverflow)
SG (1) SG11201500234YA (enrdf_load_stackoverflow)
WO (1) WO2014014834A1 (enrdf_load_stackoverflow)
ZA (1) ZA201500664B (enrdf_load_stackoverflow)

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ES2362032T3 (es) 2003-06-06 2011-06-27 Fibrogen, Inc. Compuestos de heteroarilo que contienen nitrógeno y su uso en el aumento de eritropoyetina endógena.
EP2370422B1 (en) 2008-11-14 2019-06-05 Fibrogen, Inc. Thiochromene derivatives as hif hydroxylase inhibitors
BR112015001106B1 (pt) 2012-07-16 2021-11-09 Fibrogen, Inc Métodos para a produção de compostos de isoquinolina
LT3470397T (lt) 2012-07-16 2022-02-25 Fibrogen, Inc. Prolilo hidroksilazės inhibitoriaus kristalinės formos
US8883823B2 (en) 2012-07-16 2014-11-11 Fibrogen, Inc. Crystalline forms of a prolyl hydroxylase inhibitor
US20160120859A1 (en) 2013-06-06 2016-05-05 Fibrogen, Inc. Pharmaceutical formulations of a hif hydroxylase inhibitor
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JP6506390B2 (ja) 2014-09-02 2019-04-24 サンシャイン・レイク・ファーマ・カンパニー・リミテッドＳｕｎｓｈｉｎｅ Ｌａｋｅ Ｐｈａｒｍａ Ｃｏ．，Ｌｔｄ． キノリノン系化合物及びその薬物への使用
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CN104447547B (zh) * 2014-11-10 2017-04-19 苏州康润医药有限公司 4‑氨基异喹啉‑8‑甲酸甲酯的合成方法
CN106146490B (zh) * 2015-03-27 2018-10-23 沈阳三生制药有限责任公司 被芳氧基或杂芳氧基取代的5-羟基-1,7-萘啶化合物、其制备方法及其制药用途
CN104892509B (zh) * 2015-06-04 2018-03-09 苏州明锐医药科技有限公司 诺得司他的制备方法
CN106187888A (zh) * 2016-07-18 2016-12-07 江苏德源药业股份有限公司 Fg‑4592单晶及其制备方法
CN106478503A (zh) * 2016-09-29 2017-03-08 上海勋和医药科技有限公司 Roxadustat中间体的制备方法
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CN107954931B (zh) * 2016-10-17 2021-06-22 上海医药集团青岛国风药业股份有限公司 一种诺得司他的制备方法
CN110225753B (zh) * 2017-01-28 2022-12-09 金凯(辽宁)生命科技股份有限公司 用于制备5-苯氧基-1(3h)异苯并呋喃酮的方法
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CN110218184B (zh) * 2018-03-01 2022-09-27 广东东阳光药业有限公司 诺德司他共晶及其制备方法
CN115246789B (zh) * 2018-03-16 2023-10-17 上海医药集团青岛国风药业股份有限公司 一种诺得司他的制备方法
CN110526813B (zh) * 2018-05-24 2022-06-28 杭州科巢生物科技有限公司 异喹啉化合物的制备方法及其中间体
WO2019233321A1 (zh) 2018-06-05 2019-12-12 沈阳化工大学 一种三氟乙基硫醚(亚砜)取代苯类化合物及其用途
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CN112441975B (zh) * 2019-09-03 2023-10-31 西藏嘉信景天药业有限公司 一种罗沙司他重要中间体的制备方法
CN112679431B (zh) * 2019-10-18 2023-05-05 上海迪赛诺化学制药有限公司 一种制备异喹啉酮类化合物的方法
CN112679430B (zh) * 2019-10-18 2023-05-05 上海迪赛诺化学制药有限公司 一种制备异喹啉酮类化合物的方法
WO2021073623A1 (zh) * 2019-10-18 2021-04-22 上海迪赛诺化学制药有限公司 一种制备异喹啉酮类化合物的方法
CN113444042A (zh) * 2020-03-27 2021-09-28 南京海润医药有限公司 一种罗沙司他的制备方法
WO2021214785A1 (en) * 2020-04-21 2021-10-28 Mylan Laboratories Limited Improved process for the preparation of roxadustat
CN111533691A (zh) * 2020-06-08 2020-08-14 重庆三圣实业股份有限公司 一种罗沙司他的制备方法
CN113801060B (zh) * 2020-06-13 2025-06-27 苏州鹏旭医药科技有限公司 一种多取代异喹啉化合物的制备方法
CN114933563B (zh) * 2020-06-19 2023-04-07 济川(上海)医学科技有限公司 一种罗沙司他及其中间体的合成方法和其中间体
CN112409258A (zh) * 2020-11-20 2021-02-26 杭州科巢生物科技有限公司 一种罗沙司他的制备方法
CN114644589A (zh) * 2020-12-17 2022-06-21 鲁南制药集团股份有限公司 一种化合物n-[（4-羟基--1-甲基-3-异喹啉基）羰基]-甘氨酸的制备方法
US20230101768A1 (en) * 2021-08-13 2023-03-30 The Board Of Regents Of The University Of Texas System Method to treat manganese toxicity and manganese-induced parkinsonism in humans
CN116178260A (zh) * 2021-11-26 2023-05-30 四川国康药业有限公司 一种治疗肾性贫血的化合物及其制备方法
CN115124467A (zh) * 2022-07-11 2022-09-30 天津力生制药股份有限公司 一种罗沙司他关键中间体的制备方法
CN117486797A (zh) * 2023-11-23 2024-02-02 传健生物医药(厦门)有限公司 一种罗沙司他关键中间体及罗沙司他的制备方法

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Also Published As

Publication number Publication date
JP6196671B2 (ja) 2017-09-13
CA2879238A1 (en) 2014-01-23
HUE034409T2 (en) 2018-02-28
MY171483A (en) 2019-10-15
NZ704660A (en) 2017-10-27
KR102145272B1 (ko) 2020-08-18
ZA201500664B (en) 2017-08-30
MX2015000505A (es) 2015-07-17
US20160194285A1 (en) 2016-07-07
EP3219706A1 (en) 2017-09-20
IL236625A0 (en) 2015-02-26
AU2013290437B2 (en) 2017-11-02
IN2015KN00265A (enrdf_load_stackoverflow) 2015-06-12
HUS2200030I1 (hu) 2022-07-28
EP2872487B1 (en) 2017-04-26
BR112015001106A2 (pt) 2017-06-27
MX350922B (es) 2017-09-25
CN103435546B (zh) 2016-08-10
KR20150058147A (ko) 2015-05-28
BR112015001106B1 (pt) 2021-11-09
CN106083719A (zh) 2016-11-09
WO2014014834A1 (en) 2014-01-23
PL2872487T3 (pl) 2017-09-29
US9340511B2 (en) 2016-05-17
CN106083719B (zh) 2019-10-18
PT2872487T (pt) 2017-05-15
EP2872487A1 (en) 2015-05-20
US20150175550A1 (en) 2015-06-25
CA2879238C (en) 2021-08-10
CY2022018I2 (el) 2023-01-05
DK2872487T3 (en) 2017-06-06
US9708269B2 (en) 2017-07-18
CN103435546A (zh) 2013-12-11
ES2631655T3 (es) 2017-09-01
AU2013290437A1 (en) 2015-02-19
JP2015524409A (ja) 2015-08-24
CY2022018I1 (el) 2023-01-05
IL236625B (en) 2019-01-31

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