SG11201500234YA - Process for making isoquinoline compounds - Google Patents

Process for making isoquinoline compounds

Info

Publication number
SG11201500234YA
SG11201500234YA SG11201500234YA SG11201500234YA SG11201500234YA SG 11201500234Y A SG11201500234Y A SG 11201500234YA SG 11201500234Y A SG11201500234Y A SG 11201500234YA SG 11201500234Y A SG11201500234Y A SG 11201500234YA SG 11201500234Y A SG11201500234Y A SG 11201500234YA
Authority
SG
Singapore
Prior art keywords
isoquinoline compounds
making
making isoquinoline
compounds
isoquinoline
Prior art date
Application number
SG11201500234YA
Inventor
Michael D Thompson
Jung Min Park
Michael P Arend
Original Assignee
Fibrogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fibrogen Inc filed Critical Fibrogen Inc
Publication of SG11201500234YA publication Critical patent/SG11201500234YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epidemiology (AREA)
SG11201500234YA 2012-07-16 2013-07-15 Process for making isoquinoline compounds SG11201500234YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261672191P 2012-07-16 2012-07-16
PCT/US2013/050538 WO2014014834A1 (en) 2012-07-16 2013-07-15 Process for making isoquinoline compounds

Publications (1)

Publication Number Publication Date
SG11201500234YA true SG11201500234YA (en) 2015-02-27

Family

ID=48857024

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201500234YA SG11201500234YA (en) 2012-07-16 2013-07-15 Process for making isoquinoline compounds

Country Status (21)

Country Link
US (2) US9340511B2 (en)
EP (2) EP3219706A1 (en)
JP (1) JP6196671B2 (en)
KR (1) KR102145272B1 (en)
CN (2) CN103435546B (en)
AU (1) AU2013290437B2 (en)
BR (1) BR112015001106B1 (en)
CA (1) CA2879238C (en)
DK (1) DK2872487T3 (en)
ES (1) ES2631655T3 (en)
HU (2) HUE034409T2 (en)
IL (1) IL236625B (en)
IN (1) IN2015KN00265A (en)
MX (1) MX350922B (en)
MY (1) MY171483A (en)
NZ (1) NZ704660A (en)
PL (1) PL2872487T3 (en)
PT (1) PT2872487T (en)
SG (1) SG11201500234YA (en)
WO (1) WO2014014834A1 (en)
ZA (1) ZA201500664B (en)

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MY171483A (en) 2012-07-16 2019-10-15 Fibrogen Inc Process for making isoquinoline compounds
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CN111566090A (en) * 2017-12-01 2020-08-21 雷迪博士实验室有限公司 Preparation method of roxasistat and intermediate thereof
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CN112441975B (en) * 2019-09-03 2023-10-31 西藏嘉信景天药业有限公司 Preparation method of important intermediate of roflumilast
US20230112619A1 (en) * 2019-10-18 2023-04-13 Shanghai Desano Chemical Pharmaceutical Co., Ltd. Method for preparing isoquinolinone compounds
CN112679431B (en) * 2019-10-18 2023-05-05 上海迪赛诺化学制药有限公司 Method for preparing isoquinolinones compound
CN112679430B (en) * 2019-10-18 2023-05-05 上海迪赛诺化学制药有限公司 Method for preparing isoquinolinones compound
CN113444042A (en) * 2020-03-27 2021-09-28 南京海润医药有限公司 Preparation method of Rosxastat
CN115867537A (en) 2020-04-21 2023-03-28 迈兰实验室有限公司 Improved process for the preparation of a rasagiline base
CN111533691A (en) * 2020-06-08 2020-08-14 重庆三圣实业股份有限公司 Preparation method of Rosxastat
CN114539149A (en) * 2020-06-19 2022-05-27 济川(上海)医学科技有限公司 Compound containing isoquinoline ring, preparation method and application thereof
CN112409258A (en) * 2020-11-20 2021-02-26 杭州科巢生物科技有限公司 Preparation method of Rosxastat
CN114644589A (en) * 2020-12-17 2022-06-21 鲁南制药集团股份有限公司 Preparation method of compound N- [ (4-hydroxy-1-methyl-3-isoquinolyl) carbonyl ] -glycine
US20230101768A1 (en) * 2021-08-13 2023-03-30 The Board Of Regents Of The University Of Texas System Method to treat manganese toxicity and manganese-induced parkinsonism in humans
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Also Published As

Publication number Publication date
EP3219706A1 (en) 2017-09-20
US9340511B2 (en) 2016-05-17
CA2879238A1 (en) 2014-01-23
CN106083719A (en) 2016-11-09
ZA201500664B (en) 2017-08-30
IL236625B (en) 2019-01-31
MY171483A (en) 2019-10-15
CN103435546B (en) 2016-08-10
KR102145272B1 (en) 2020-08-18
DK2872487T3 (en) 2017-06-06
CN103435546A (en) 2013-12-11
EP2872487B1 (en) 2017-04-26
EP2872487A1 (en) 2015-05-20
MX2015000505A (en) 2015-07-17
IN2015KN00265A (en) 2015-06-12
BR112015001106B1 (en) 2021-11-09
US9708269B2 (en) 2017-07-18
BR112015001106A2 (en) 2017-06-27
CN106083719B (en) 2019-10-18
IL236625A0 (en) 2015-02-26
JP2015524409A (en) 2015-08-24
JP6196671B2 (en) 2017-09-13
AU2013290437A1 (en) 2015-02-19
ES2631655T3 (en) 2017-09-01
WO2014014834A1 (en) 2014-01-23
US20150175550A1 (en) 2015-06-25
KR20150058147A (en) 2015-05-28
AU2013290437B2 (en) 2017-11-02
MX350922B (en) 2017-09-25
HUE034409T2 (en) 2018-02-28
HUS2200030I1 (en) 2022-07-28
PL2872487T3 (en) 2017-09-29
CA2879238C (en) 2021-08-10
US20160194285A1 (en) 2016-07-07
PT2872487T (en) 2017-05-15
NZ704660A (en) 2017-10-27

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