SG11201407051XA - Substituted 3, 4 - dihydro - 2h - pyrido [1, 2 -a] pyrazine - 1, 6 - dione derivatives useful for the treatment of (inter alia) alzheimer's disease - Google Patents

Substituted 3, 4 - dihydro - 2h - pyrido [1, 2 -a] pyrazine - 1, 6 - dione derivatives useful for the treatment of (inter alia) alzheimer's disease

Info

Publication number
SG11201407051XA
SG11201407051XA SG11201407051XA SG11201407051XA SG11201407051XA SG 11201407051X A SG11201407051X A SG 11201407051XA SG 11201407051X A SG11201407051X A SG 11201407051XA SG 11201407051X A SG11201407051X A SG 11201407051XA SG 11201407051X A SG11201407051X A SG 11201407051XA
Authority
SG
Singapore
Prior art keywords
pyrido
pyrazine
alzheimer
dihydro
disease
Prior art date
Application number
SG11201407051XA
Other languages
English (en)
Inventor
Henricus Jacobus Maria Gijsen
Gregor James Macdonald
François Paul Bischoff
Frederik Jan Rita Rombouts
Adriana Ingrid Velter
Roosbroeck Yves Emiel Maria Van
Andrés Avelino Trabanco-Suárez
Diego Sergio-Alvar Alonso-De
Original Assignee
Janssen Pharmaceuticals Inc
Cellzome Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceuticals Inc, Cellzome Ltd filed Critical Janssen Pharmaceuticals Inc
Publication of SG11201407051XA publication Critical patent/SG11201407051XA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
SG11201407051XA 2012-05-16 2013-05-16 Substituted 3, 4 - dihydro - 2h - pyrido [1, 2 -a] pyrazine - 1, 6 - dione derivatives useful for the treatment of (inter alia) alzheimer's disease SG11201407051XA (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12168186 2012-05-16
EP12195875 2012-12-06
EP12197010 2012-12-13
EP13159178 2013-03-14
PCT/IB2013/054014 WO2013171712A1 (en) 2012-05-16 2013-05-16 Substituted 3, 4 - dihydro - 2h - pyrido [1, 2 -a] pyrazine - 1, 6 - dione derivatives useful for the treatment of (inter alia) alzheimer's disease

Publications (1)

Publication Number Publication Date
SG11201407051XA true SG11201407051XA (en) 2014-11-27

Family

ID=48670031

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201407051XA SG11201407051XA (en) 2012-05-16 2013-05-16 Substituted 3, 4 - dihydro - 2h - pyrido [1, 2 -a] pyrazine - 1, 6 - dione derivatives useful for the treatment of (inter alia) alzheimer's disease

Country Status (16)

Country Link
US (1) US9181245B2 (pt)
EP (1) EP2850083B1 (pt)
JP (1) JP6106745B2 (pt)
KR (1) KR102096625B1 (pt)
CN (1) CN104583208B (pt)
AU (1) AU2013261023B2 (pt)
BR (1) BR112014028395B1 (pt)
CA (1) CA2870347C (pt)
EA (1) EA027242B1 (pt)
ES (1) ES2585009T3 (pt)
HK (1) HK1207645A1 (pt)
IL (1) IL235659A (pt)
MX (1) MX355164B (pt)
NZ (1) NZ702611A (pt)
SG (1) SG11201407051XA (pt)
WO (1) WO2013171712A1 (pt)

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Also Published As

Publication number Publication date
WO2013171712A1 (en) 2013-11-21
AU2013261023B2 (en) 2016-11-24
CA2870347C (en) 2020-08-04
AU2013261023A1 (en) 2014-10-30
CA2870347A1 (en) 2013-11-21
EA201492112A1 (ru) 2015-04-30
MX355164B (es) 2018-04-06
US9181245B2 (en) 2015-11-10
JP6106745B2 (ja) 2017-04-05
CN104583208B (zh) 2016-09-28
ES2585009T3 (es) 2016-10-03
KR20150009548A (ko) 2015-01-26
EP2850083A1 (en) 2015-03-25
IL235659A (en) 2017-02-28
IL235659A0 (en) 2015-02-01
JP2015517517A (ja) 2015-06-22
MX2014013957A (es) 2015-02-12
KR102096625B1 (ko) 2020-04-03
EP2850083B1 (en) 2016-04-27
NZ702611A (en) 2016-10-28
CN104583208A (zh) 2015-04-29
HK1207645A1 (en) 2016-02-05
EA027242B1 (ru) 2017-07-31
BR112014028395B1 (pt) 2022-02-01
BR112014028395A2 (pt) 2017-06-27
US20150141411A1 (en) 2015-05-21

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