SG11201402390PA - Polymyxin derivatives - Google Patents
Polymyxin derivativesInfo
- Publication number
- SG11201402390PA SG11201402390PA SG11201402390PA SG11201402390PA SG11201402390PA SG 11201402390P A SG11201402390P A SG 11201402390PA SG 11201402390P A SG11201402390P A SG 11201402390PA SG 11201402390P A SG11201402390P A SG 11201402390PA SG 11201402390P A SG11201402390P A SG 11201402390PA
- Authority
- SG
- Singapore
- Prior art keywords
- polymyxin derivatives
- polymyxin
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161561361P | 2011-11-18 | 2011-11-18 | |
| PCT/GB2012/052844 WO2013072695A1 (en) | 2011-11-18 | 2012-11-16 | Polymyxin derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201402390PA true SG11201402390PA (en) | 2014-06-27 |
Family
ID=47297320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201402390PA SG11201402390PA (en) | 2011-11-18 | 2012-11-16 | Polymyxin derivatives |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9234006B2 (enExample) |
| EP (1) | EP2780357A1 (enExample) |
| JP (1) | JP6185920B2 (enExample) |
| KR (1) | KR20140091724A (enExample) |
| CN (1) | CN103946233A (enExample) |
| AU (1) | AU2012338571B2 (enExample) |
| BR (1) | BR112014012016A2 (enExample) |
| CA (1) | CA2855916A1 (enExample) |
| CO (1) | CO7061068A2 (enExample) |
| EA (1) | EA024792B1 (enExample) |
| IL (1) | IL232278A0 (enExample) |
| MX (1) | MX355217B (enExample) |
| SG (1) | SG11201402390PA (enExample) |
| TW (1) | TWI608019B (enExample) |
| WO (1) | WO2013072695A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2855916A1 (en) | 2011-11-18 | 2013-05-23 | Novacta Biosystems Limited | Polymyxin derivatives |
| HRP20220898T1 (hr) * | 2013-05-22 | 2022-10-14 | Spero Therapeutics, Inc. | Derivati polimiksina i njihova upotreba u kombinacijskoj terapiji zajedno s različitim antibioticima |
| TWI709575B (zh) * | 2014-03-11 | 2020-11-11 | 美商斯佩羅治療學股份有限公司 | 多黏菌素衍生物以及其與不同抗生素一起之組合療法的用途 |
| PL3126376T3 (pl) | 2014-04-01 | 2024-10-28 | Monash University | Pochodne polimyksyn jako związki przeciwdrobnoustrojowe |
| JP7349773B2 (ja) * | 2014-11-26 | 2023-09-25 | スペロ・セラピューティクス・インコーポレーテッド | 化合物 |
| WO2016100578A2 (en) | 2014-12-16 | 2016-06-23 | Micurx Pharmaceuticals, Inc. | Antimicrobial polymyxins for treatment of bacterial infections |
| FI126143B (en) | 2015-01-15 | 2016-07-15 | Northern Antibiotics Oy | Polymyxine derivative and its uses |
| US9763996B2 (en) | 2015-01-16 | 2017-09-19 | Northern Antibiotics, Ltd. | Polymyxin derivative and uses thereof |
| US10322187B2 (en) | 2015-08-10 | 2019-06-18 | Lehigh University | Reduced toxicity molecular conjugates of anti-fungal agents |
| AU2016331658B2 (en) * | 2015-09-29 | 2021-04-01 | Monash University | Antimicrobial polymyxin derivative compounds |
| EP3512544B1 (en) * | 2016-09-13 | 2020-10-28 | Centauri Therapeutics Limited | Peptide compounds and therapeutic uses thereof |
| CN108226315B (zh) * | 2016-12-15 | 2022-04-12 | 上海医药工业研究院 | 一种检测多黏菌素e残留量的分析方法 |
| WO2019084628A1 (en) * | 2017-11-02 | 2019-05-09 | The University Of Queensland | Peptide antibiotics |
| UA128162C2 (uk) | 2018-06-25 | 2024-04-24 | Сперо Терапьютікс, Інк. | Поліміксинові сполуки |
| CN111690040A (zh) * | 2019-03-12 | 2020-09-22 | 上海来益生物药物研究开发中心有限责任公司 | 多粘菌素衍生物、其制备方法和应用 |
| JP7045520B2 (ja) * | 2020-01-02 | 2022-03-31 | 上海上薬第一生化薬業有限公司 | ポリミキシンｂ成分又はその塩、その製造方法及び使用 |
| CN115298198A (zh) | 2020-01-21 | 2022-11-04 | 上海盟科药业股份有限公司 | 用于肾相关癌症靶向治疗的新型化合物和组合物 |
| TW202233649A (zh) | 2020-11-06 | 2022-09-01 | 美商斯佩羅治療學股份有限公司 | 化合物 |
| CN112755174B (zh) * | 2021-02-26 | 2022-11-18 | 沈阳药科大学 | 多粘菌素衍生物及其制备方法和应用 |
| CN115490757B (zh) * | 2021-06-18 | 2025-10-14 | 华南理工大学 | 活性氧自由基响应的多粘菌素前药化合物及其应用 |
| NL2030897B1 (en) * | 2022-02-11 | 2023-08-18 | Univ Leiden | Antibiotic compounds, formulations and methods of use |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2128617A (en) | 1982-10-06 | 1984-05-02 | Martti Vaara | Polypeptides for use in antibacterial therapy |
| WO1988000950A2 (fr) | 1986-08-06 | 1988-02-11 | Fauchere Jean Luc | Fabrication de conjugues a liaisons de covalence a partir d'un antibiotique et d'un derive non toxique de la polymyxine b |
| US20010021697A1 (en) | 1987-09-14 | 2001-09-13 | Henning Lowenstein | Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components |
| TW274552B (enExample) | 1992-05-26 | 1996-04-21 | Hoechst Ag | |
| US5767068A (en) | 1997-02-13 | 1998-06-16 | Pathogenesis Corporation | Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections |
| CN1886128A (zh) | 2003-09-30 | 2006-12-27 | 柯西有限公司 | 用于治疗灼伤的组合物及方法 |
| US20060004185A1 (en) | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| CN103059106B (zh) * | 2006-08-11 | 2015-01-14 | 北方抗生素有限公司 | 多粘菌素衍生物及其用途 |
| US8193148B2 (en) | 2008-02-08 | 2012-06-05 | Northern Antibiotics Ltd. | Short fatty acid tail polymyxin derivatives and uses thereof |
| US8329645B2 (en) * | 2008-02-08 | 2012-12-11 | Northern Antibiotics Ltd. | Polymyxin derivatives and uses thereof |
| FI20085469A0 (fi) * | 2008-02-08 | 2008-05-16 | Northern Antibiotics Oy | Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä |
| ES2334547B1 (es) | 2008-09-10 | 2010-12-03 | Universidad De Barcelona | Compuestos peptidicos antibacterianos. |
| TW201035111A (en) | 2008-12-23 | 2010-10-01 | Biosource Pharm Inc | Antibiotic compositions for the treatment of gram negative infections |
| CN101851270A (zh) | 2009-04-03 | 2010-10-06 | 梁浩 | 一种多粘菌素衍生物及其制备方法 |
| WO2010130007A1 (en) | 2009-05-14 | 2010-11-18 | Monash University | Antimicrobial compounds |
| US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| WO2012051663A1 (en) | 2010-10-21 | 2012-04-26 | Monash University | Antimicrobial compounds |
| WO2012168820A1 (en) * | 2011-06-08 | 2012-12-13 | Pfizer Inc. | Polymyxin derivatives useful as antibacterial agents |
| CA2855916A1 (en) | 2011-11-18 | 2013-05-23 | Novacta Biosystems Limited | Polymyxin derivatives |
| HRP20220898T1 (hr) | 2013-05-22 | 2022-10-14 | Spero Therapeutics, Inc. | Derivati polimiksina i njihova upotreba u kombinacijskoj terapiji zajedno s različitim antibioticima |
| TWI709575B (zh) * | 2014-03-11 | 2020-11-11 | 美商斯佩羅治療學股份有限公司 | 多黏菌素衍生物以及其與不同抗生素一起之組合療法的用途 |
-
2012
- 2012-11-16 CA CA2855916A patent/CA2855916A1/en not_active Abandoned
- 2012-11-16 EA EA201490634A patent/EA024792B1/ru not_active IP Right Cessation
- 2012-11-16 BR BR112014012016A patent/BR112014012016A2/pt not_active Application Discontinuation
- 2012-11-16 EP EP12797961.5A patent/EP2780357A1/en not_active Withdrawn
- 2012-11-16 KR KR1020147014427A patent/KR20140091724A/ko not_active Withdrawn
- 2012-11-16 TW TW101142961A patent/TWI608019B/zh not_active IP Right Cessation
- 2012-11-16 SG SG11201402390PA patent/SG11201402390PA/en unknown
- 2012-11-16 WO PCT/GB2012/052844 patent/WO2013072695A1/en not_active Ceased
- 2012-11-16 US US14/356,868 patent/US9234006B2/en active Active
- 2012-11-16 JP JP2014541753A patent/JP6185920B2/ja not_active Expired - Fee Related
- 2012-11-16 CN CN201280055987.6A patent/CN103946233A/zh active Pending
- 2012-11-16 MX MX2014005542A patent/MX355217B/es active IP Right Grant
- 2012-11-16 AU AU2012338571A patent/AU2012338571B2/en not_active Ceased
-
2014
- 2014-04-28 IL IL232278A patent/IL232278A0/en unknown
- 2014-06-13 CO CO14128978A patent/CO7061068A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20150031602A1 (en) | 2015-01-29 |
| WO2013072695A1 (en) | 2013-05-23 |
| EA024792B1 (ru) | 2016-10-31 |
| CO7061068A2 (es) | 2014-09-19 |
| CA2855916A1 (en) | 2013-05-23 |
| CN103946233A (zh) | 2014-07-23 |
| EA201490634A1 (ru) | 2014-12-30 |
| JP6185920B2 (ja) | 2017-08-23 |
| TWI608019B (zh) | 2017-12-11 |
| BR112014012016A2 (pt) | 2017-05-16 |
| US9234006B2 (en) | 2016-01-12 |
| JP2014533678A (ja) | 2014-12-15 |
| IL232278A0 (en) | 2014-06-30 |
| KR20140091724A (ko) | 2014-07-22 |
| TW201326215A (zh) | 2013-07-01 |
| AU2012338571A1 (en) | 2014-05-22 |
| MX355217B (es) | 2018-04-10 |
| EP2780357A1 (en) | 2014-09-24 |
| AU2012338571B2 (en) | 2016-06-16 |
| MX2014005542A (es) | 2014-10-24 |
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