PL3126376T3 - Pochodne polimyksyn jako związki przeciwdrobnoustrojowe - Google Patents

Pochodne polimyksyn jako związki przeciwdrobnoustrojowe

Info

Publication number
PL3126376T3
PL3126376T3 PL15772554.0T PL15772554T PL3126376T3 PL 3126376 T3 PL3126376 T3 PL 3126376T3 PL 15772554 T PL15772554 T PL 15772554T PL 3126376 T3 PL3126376 T3 PL 3126376T3
Authority
PL
Poland
Prior art keywords
antimicrobial compounds
polymyxin derivatives
polymyxin
derivatives
antimicrobial
Prior art date
Application number
PL15772554.0T
Other languages
English (en)
Inventor
Jian Li
Roger Nation
Tony Velkov
Philip Thompson
Kade D. Roberts
Original Assignee
Monash University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2014901182A external-priority patent/AU2014901182A0/en
Application filed by Monash University filed Critical Monash University
Publication of PL3126376T3 publication Critical patent/PL3126376T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62Polymyxins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL15772554.0T 2014-04-01 2015-04-01 Pochodne polimyksyn jako związki przeciwdrobnoustrojowe PL3126376T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2014901182A AU2014901182A0 (en) 2014-04-01 Antimicrobial compounds
PCT/AU2015/050149 WO2015149131A1 (en) 2014-04-01 2015-04-01 Polymyxin derivatives as antimicrobial compounds

Publications (1)

Publication Number Publication Date
PL3126376T3 true PL3126376T3 (pl) 2024-10-28

Family

ID=54239144

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15772554.0T PL3126376T3 (pl) 2014-04-01 2015-04-01 Pochodne polimyksyn jako związki przeciwdrobnoustrojowe

Country Status (11)

Country Link
US (2) US10047126B2 (pl)
EP (2) EP4477272A3 (pl)
JP (3) JP2017512818A (pl)
CN (1) CN106414480B (pl)
AU (1) AU2015240435B2 (pl)
CA (1) CA2944550C (pl)
ES (1) ES2999407T3 (pl)
HU (1) HUE068512T2 (pl)
NZ (1) NZ724798A (pl)
PL (1) PL3126376T3 (pl)
WO (1) WO2015149131A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2730012C2 (ru) 2013-05-22 2020-08-14 Сперо Терапьютикс, Инк. Производные полимиксина и их применение в комбинированной терапии совместно с различными антибиотиками
EP3224273A1 (en) 2014-11-26 2017-10-04 New Pharma Licence Holdings Limited Compounds
CN107257803B (zh) 2014-12-16 2021-02-05 上海盟科药业股份有限公司 用于治疗细菌感染的多粘菌素类抗菌剂
JP7367950B2 (ja) * 2015-09-29 2023-10-24 モナッシュ ユニバーシティ 抗菌性ポリミキシン誘導体化合物
US20190315806A1 (en) * 2016-12-16 2019-10-17 Institute Of Medicinal Biotechnology, Chinese Academy Of Medical Sciences Polymyxin derivative, preparation method and application thereof
GB201703898D0 (en) * 2017-03-10 2017-04-26 Helperby Therapeautics Ltd Method
EP3704135A4 (en) * 2017-11-02 2022-04-27 The University of Queensland PEPTIDE ANTIBIOTICS
TWI851584B (zh) 2018-06-25 2024-08-11 新加坡商雲頂新耀股份有限公司 化合物
AU2019343188A1 (en) 2018-09-21 2021-05-20 Aufbau Medical Innovations Limited Compositions and methods for glaucoma
CN110845579B (zh) * 2019-08-08 2022-04-19 上海市食品药品检验研究院 一种多黏菌素e组分及其光化学产物和液相色谱-质谱分析方法
CN115298198A (zh) 2020-01-21 2022-11-04 上海盟科药业股份有限公司 用于肾相关癌症靶向治疗的新型化合物和组合物
AU2021241476A1 (en) * 2020-03-25 2022-11-03 Aufbau Medical Innovations Limited Processes and agents for glaucoma
WO2022098950A1 (en) * 2020-11-06 2022-05-12 Spero Therapeutics, Inc. Compounds
CN117083288A (zh) * 2021-03-31 2023-11-17 江苏奥赛康药业有限公司 一种多粘菌素衍生物的硫酸盐及其药物组合物
KR20250037611A (ko) * 2023-09-07 2025-03-18 웰펩 주식회사 그람 음성균 및 다제내성 그람 음성균에 우수한 항균 활성을 갖는 신규 폴리믹신 유사체, 이를 포함하는 항균용 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
WO2006045156A1 (en) * 2004-10-29 2006-05-04 Monash University Therapy for multi-drug resistant microorganisms
KR100750658B1 (ko) * 2005-12-09 2007-08-20 한국생명공학연구원 폴리믹신 생합성 효소 및 이를 코딩하는 유전자 군
US8329645B2 (en) * 2008-02-08 2012-12-11 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
NZ593892A (en) * 2008-12-23 2013-11-29 Biosource Pharm Inc Antibiotic compositions for the treatment of gram negative infections
WO2010130007A1 (en) 2009-05-14 2010-11-18 Monash University Antimicrobial compounds
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
WO2012051663A1 (en) 2010-10-21 2012-04-26 Monash University Antimicrobial compounds
WO2012168820A1 (en) 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
MX355217B (es) 2011-11-18 2018-04-10 New Pharma Licence Holdings Ltd Derivados de polimixina.
SI3116897T1 (sl) 2014-03-11 2022-06-30 Spero Therapeutics, Inc. Derivati polimiksina in njihova uporaba v kombinacijskem zdravljenju skupaj z različnimi antibiotiki
JP7367950B2 (ja) 2015-09-29 2023-10-24 モナッシュ ユニバーシティ 抗菌性ポリミキシン誘導体化合物

Also Published As

Publication number Publication date
US10047126B2 (en) 2018-08-14
WO2015149131A1 (en) 2015-10-08
AU2015240435A1 (en) 2016-10-20
US20170137469A1 (en) 2017-05-18
CA2944550C (en) 2021-05-25
JP7117021B2 (ja) 2022-08-12
AU2015240435B2 (en) 2019-09-19
USRE48335E1 (en) 2020-12-01
JP2020169184A (ja) 2020-10-15
JP2017512818A (ja) 2017-05-25
HUE068512T2 (hu) 2024-12-28
NZ724798A (en) 2020-05-29
CN106414480A (zh) 2017-02-15
EP3126376C0 (en) 2024-08-21
CA2944550A1 (en) 2015-10-08
CN106414480B (zh) 2020-08-04
EP3126376A4 (en) 2017-10-25
EP4477272A2 (en) 2024-12-18
JP2019108396A (ja) 2019-07-04
EP4477272A3 (en) 2025-03-12
EP3126376B1 (en) 2024-08-21
EP3126376A1 (en) 2017-02-08
ES2999407T3 (en) 2025-02-25

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