TW274552B - - Google Patents
Info
- Publication number
- TW274552B TW274552B TW081108642A TW81108642A TW274552B TW 274552 B TW274552 B TW 274552B TW 081108642 A TW081108642 A TW 081108642A TW 81108642 A TW81108642 A TW 81108642A TW 274552 B TW274552 B TW 274552B
- Authority
- TW
- Taiwan
- Prior art keywords
- formula
- basic
- amino acid
- physiologically tolerated
- tolerated salts
- Prior art date
Links
- 150000008574 D-amino acids Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 230000007935 neutral effect Effects 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- -1 amino, carboxyl Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 210000004400 mucous membrane Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4217350 | 1992-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW274552B true TW274552B (enExample) | 1996-04-21 |
Family
ID=6459729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW081108642A TW274552B (enExample) | 1992-05-26 | 1992-10-30 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5565423A (enExample) |
| EP (1) | EP0571921B1 (enExample) |
| JP (1) | JPH0672899A (enExample) |
| KR (1) | KR940005669A (enExample) |
| AT (1) | ATE144991T1 (enExample) |
| AU (1) | AU665676B2 (enExample) |
| CA (1) | CA2096889A1 (enExample) |
| DE (1) | DE59304389D1 (enExample) |
| DK (1) | DK0571921T3 (enExample) |
| ES (1) | ES2096140T3 (enExample) |
| FI (1) | FI932351A7 (enExample) |
| GR (1) | GR3021570T3 (enExample) |
| HU (1) | HUT64776A (enExample) |
| IL (1) | IL105795A (enExample) |
| NO (1) | NO931888L (enExample) |
| NZ (1) | NZ247680A (enExample) |
| TW (1) | TW274552B (enExample) |
| ZA (1) | ZA933629B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8765177B2 (en) * | 1997-09-12 | 2014-07-01 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| US7153845B2 (en) * | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| EP1487474A4 (en) * | 2002-02-25 | 2006-11-29 | Chiron Corp | INTRANASAL ADMINISTRATION OF MC4-R AGONISTS |
| US6803046B2 (en) * | 2002-08-16 | 2004-10-12 | Bracco International B.V. | Sincalide formulations |
| US7812120B2 (en) | 2003-03-21 | 2010-10-12 | Par Pharmaceutical, Inc. | Nasal calcitonin formulations containing chlorobutanol |
| US20060004185A1 (en) * | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| WO2008128786A1 (en) * | 2007-04-23 | 2008-10-30 | Bayer Schering Pharma Aktiengesellschaft | Combination of progesterone-receptor antagonist together with a lutein-hormone-releasing hormone agonist and antagonist for use in brca mediated diseases |
| TW201035111A (en) | 2008-12-23 | 2010-10-01 | Biosource Pharm Inc | Antibiotic compositions for the treatment of gram negative infections |
| US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| SG11201402390PA (en) | 2011-11-18 | 2014-06-27 | Novacta Biosystems Ltd | Polymyxin derivatives |
| JP6643758B2 (ja) | 2013-05-22 | 2020-02-12 | スペロ・セラピューティクス・インコーポレーテッド | 異なった抗生物質と一緒の組合せ療法におけるポリミキシン誘導体及びその使用 |
| EP3224273A1 (en) | 2014-11-26 | 2017-10-04 | New Pharma Licence Holdings Limited | Compounds |
| FI126143B (en) * | 2015-01-15 | 2016-07-15 | Northern Antibiotics Oy | Polymyxine derivative and its uses |
| US11110063B2 (en) | 2017-08-25 | 2021-09-07 | MAIA Pharmaceuticals, Inc. | Storage stable sincalide formulations |
| FI3810633T3 (fi) | 2018-06-25 | 2024-02-09 | Spero Therapeutics Inc | Yhdisteitä |
| US20220226479A1 (en) * | 2019-03-25 | 2022-07-21 | University Of Tsukuba | Cell layer permeation promoter. composition for facilitating drug absorption. and pharmaceutical composition |
| CN117649950B (zh) * | 2024-01-29 | 2024-05-17 | 北京大学第三医院（北京大学第三临床医学院） | 一种催产素药物作用动力学模型及其构建方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2124060B1 (enExample) * | 1971-02-02 | 1974-04-12 | Rhone Poulenc Sa | |
| AU7753787A (en) * | 1986-08-06 | 1988-02-24 | Jean-Luc Fauchere | Production of covalent-linked conjugates from an antibiotic and a non-toxic derivative of polymyxine b |
| DE3726324A1 (de) * | 1987-08-07 | 1989-02-16 | Hoechst Ag | Cyclopeptide als resorptionsfoerderer bei applikation auf die schleimhaeute |
| US5177059A (en) * | 1989-11-15 | 1993-01-05 | Sandoz Ltd. | Polymyxin B conjugates |
-
1992
- 1992-10-30 TW TW081108642A patent/TW274552B/zh active
-
1993
- 1993-05-24 HU HU9301520A patent/HUT64776A/hu unknown
- 1993-05-24 ES ES93108353T patent/ES2096140T3/es not_active Expired - Lifetime
- 1993-05-24 FI FI932351A patent/FI932351A7/fi unknown
- 1993-05-24 DE DE59304389T patent/DE59304389D1/de not_active Expired - Lifetime
- 1993-05-24 KR KR1019930008937A patent/KR940005669A/ko active Pending
- 1993-05-24 IL IL105795A patent/IL105795A/en not_active IP Right Cessation
- 1993-05-24 NZ NZ247680A patent/NZ247680A/en unknown
- 1993-05-24 EP EP93108353A patent/EP0571921B1/de not_active Expired - Lifetime
- 1993-05-24 DK DK93108353.9T patent/DK0571921T3/da active
- 1993-05-24 AT AT93108353T patent/ATE144991T1/de not_active IP Right Cessation
- 1993-05-25 NO NO931888A patent/NO931888L/no not_active Application Discontinuation
- 1993-05-25 JP JP5122478A patent/JPH0672899A/ja active Pending
- 1993-05-25 AU AU38766/93A patent/AU665676B2/en not_active Ceased
- 1993-05-25 CA CA002096889A patent/CA2096889A1/en not_active Abandoned
- 1993-05-25 ZA ZA933629A patent/ZA933629B/xx unknown
-
1995
- 1995-04-07 US US08/418,882 patent/US5565423A/en not_active Expired - Fee Related
-
1996
- 1996-11-07 GR GR960402904T patent/GR3021570T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0571921A3 (enExample) | 1994-01-12 |
| ATE144991T1 (de) | 1996-11-15 |
| EP0571921A2 (de) | 1993-12-01 |
| US5565423A (en) | 1996-10-15 |
| DE59304389D1 (de) | 1996-12-12 |
| ZA933629B (en) | 1993-12-20 |
| HU9301520D0 (en) | 1993-09-28 |
| KR940005669A (ko) | 1994-03-22 |
| NO931888L (no) | 1993-11-29 |
| ES2096140T3 (es) | 1997-03-01 |
| FI932351A0 (fi) | 1993-05-24 |
| AU3876693A (en) | 1993-12-02 |
| IL105795A (en) | 1998-03-10 |
| GR3021570T3 (en) | 1997-02-28 |
| DK0571921T3 (da) | 1997-04-01 |
| HUT64776A (en) | 1994-02-28 |
| NO931888D0 (no) | 1993-05-25 |
| EP0571921B1 (de) | 1996-11-06 |
| FI932351A7 (fi) | 1993-11-27 |
| NZ247680A (en) | 1995-07-26 |
| JPH0672899A (ja) | 1994-03-15 |
| IL105795A0 (en) | 1993-09-22 |
| AU665676B2 (en) | 1996-01-11 |
| CA2096889A1 (en) | 1993-11-27 |
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