DK0571921T3 - Cyclopeptider og deres anvendelse som resorptionsfremmende midler ved påføring på slimhinder - Google Patents
Cyclopeptider og deres anvendelse som resorptionsfremmende midler ved påføring på slimhinderInfo
- Publication number
- DK0571921T3 DK0571921T3 DK93108353.9T DK93108353T DK0571921T3 DK 0571921 T3 DK0571921 T3 DK 0571921T3 DK 93108353 T DK93108353 T DK 93108353T DK 0571921 T3 DK0571921 T3 DK 0571921T3
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- basic
- amino acid
- physiologically tolerated
- tolerated salts
- Prior art date
Links
- 210000004400 mucous membrane Anatomy 0.000 title abstract 2
- 102000001189 Cyclic Peptides Human genes 0.000 title 1
- 108010069514 Cyclic Peptides Proteins 0.000 title 1
- 150000008574 D-amino acids Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 230000007935 neutral effect Effects 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- -1 amino, carboxyl Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4217350 | 1992-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0571921T3 true DK0571921T3 (da) | 1997-04-01 |
Family
ID=6459729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93108353.9T DK0571921T3 (da) | 1992-05-26 | 1993-05-24 | Cyclopeptider og deres anvendelse som resorptionsfremmende midler ved påføring på slimhinder |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5565423A (enExample) |
| EP (1) | EP0571921B1 (enExample) |
| JP (1) | JPH0672899A (enExample) |
| KR (1) | KR940005669A (enExample) |
| AT (1) | ATE144991T1 (enExample) |
| AU (1) | AU665676B2 (enExample) |
| CA (1) | CA2096889A1 (enExample) |
| DE (1) | DE59304389D1 (enExample) |
| DK (1) | DK0571921T3 (enExample) |
| ES (1) | ES2096140T3 (enExample) |
| FI (1) | FI932351A7 (enExample) |
| GR (1) | GR3021570T3 (enExample) |
| HU (1) | HUT64776A (enExample) |
| IL (1) | IL105795A (enExample) |
| NO (1) | NO931888L (enExample) |
| NZ (1) | NZ247680A (enExample) |
| TW (1) | TW274552B (enExample) |
| ZA (1) | ZA933629B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8765177B2 (en) * | 1997-09-12 | 2014-07-01 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| US7153845B2 (en) * | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| US20030229025A1 (en) * | 2002-02-25 | 2003-12-11 | Chiron Corporation | Intranasal administration of MC4-R agonists |
| US6803046B2 (en) * | 2002-08-16 | 2004-10-12 | Bracco International B.V. | Sincalide formulations |
| US7812120B2 (en) | 2003-03-21 | 2010-10-12 | Par Pharmaceutical, Inc. | Nasal calcitonin formulations containing chlorobutanol |
| US20060004185A1 (en) * | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| JP2010524996A (ja) * | 2007-04-23 | 2010-07-22 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | Ｂｒｃａ媒介性疾患における使用のための、プロゲステロン受容体拮抗薬と、ルテインホルモン放出ホルモン作動薬および拮抗薬との組み合わせ |
| TW201035111A (en) | 2008-12-23 | 2010-10-01 | Biosource Pharm Inc | Antibiotic compositions for the treatment of gram negative infections |
| US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| CA2855916A1 (en) | 2011-11-18 | 2013-05-23 | Novacta Biosystems Limited | Polymyxin derivatives |
| HRP20220898T1 (hr) | 2013-05-22 | 2022-10-14 | Spero Therapeutics, Inc. | Derivati polimiksina i njihova upotreba u kombinacijskoj terapiji zajedno s različitim antibioticima |
| JP7349773B2 (ja) | 2014-11-26 | 2023-09-25 | スペロ・セラピューティクス・インコーポレーテッド | 化合物 |
| FI126143B (en) * | 2015-01-15 | 2016-07-15 | Northern Antibiotics Oy | Polymyxine derivative and its uses |
| US11110063B2 (en) | 2017-08-25 | 2021-09-07 | MAIA Pharmaceuticals, Inc. | Storage stable sincalide formulations |
| UA128162C2 (uk) | 2018-06-25 | 2024-04-24 | Сперо Терапьютікс, Інк. | Поліміксинові сполуки |
| CN113874045B (zh) * | 2019-03-25 | 2023-11-24 | 国立大学法人筑波大学 | 细胞层渗透促进剂、药剂吸收辅助用组合物及药物组合物 |
| CN116332993A (zh) * | 2023-03-13 | 2023-06-27 | 遵义医科大学 | 一种氨基噻唑肟酰胺类化合物及其制备方法和应用 |
| CN117649950B (zh) * | 2024-01-29 | 2024-05-17 | 北京大学第三医院（北京大学第三临床医学院） | 一种催产素药物作用动力学模型及其构建方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2124060B1 (enExample) * | 1971-02-02 | 1974-04-12 | Rhone Poulenc Sa | |
| WO1988000950A2 (fr) * | 1986-08-06 | 1988-02-11 | Fauchere Jean Luc | Fabrication de conjugues a liaisons de covalence a partir d'un antibiotique et d'un derive non toxique de la polymyxine b |
| DE3726324A1 (de) * | 1987-08-07 | 1989-02-16 | Hoechst Ag | Cyclopeptide als resorptionsfoerderer bei applikation auf die schleimhaeute |
| US5177059A (en) * | 1989-11-15 | 1993-01-05 | Sandoz Ltd. | Polymyxin B conjugates |
-
1992
- 1992-10-30 TW TW081108642A patent/TW274552B/zh active
-
1993
- 1993-05-24 EP EP93108353A patent/EP0571921B1/de not_active Expired - Lifetime
- 1993-05-24 IL IL105795A patent/IL105795A/en not_active IP Right Cessation
- 1993-05-24 HU HU9301520A patent/HUT64776A/hu unknown
- 1993-05-24 AT AT93108353T patent/ATE144991T1/de not_active IP Right Cessation
- 1993-05-24 DK DK93108353.9T patent/DK0571921T3/da active
- 1993-05-24 DE DE59304389T patent/DE59304389D1/de not_active Expired - Lifetime
- 1993-05-24 KR KR1019930008937A patent/KR940005669A/ko active Pending
- 1993-05-24 NZ NZ247680A patent/NZ247680A/en unknown
- 1993-05-24 FI FI932351A patent/FI932351A7/fi unknown
- 1993-05-24 ES ES93108353T patent/ES2096140T3/es not_active Expired - Lifetime
- 1993-05-25 NO NO931888A patent/NO931888L/no not_active Application Discontinuation
- 1993-05-25 CA CA002096889A patent/CA2096889A1/en not_active Abandoned
- 1993-05-25 AU AU38766/93A patent/AU665676B2/en not_active Ceased
- 1993-05-25 ZA ZA933629A patent/ZA933629B/xx unknown
- 1993-05-25 JP JP5122478A patent/JPH0672899A/ja active Pending
-
1995
- 1995-04-07 US US08/418,882 patent/US5565423A/en not_active Expired - Fee Related
-
1996
- 1996-11-07 GR GR960402904T patent/GR3021570T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0571921B1 (de) | 1996-11-06 |
| ZA933629B (en) | 1993-12-20 |
| KR940005669A (ko) | 1994-03-22 |
| US5565423A (en) | 1996-10-15 |
| NO931888D0 (no) | 1993-05-25 |
| GR3021570T3 (en) | 1997-02-28 |
| EP0571921A3 (enExample) | 1994-01-12 |
| NO931888L (no) | 1993-11-29 |
| IL105795A (en) | 1998-03-10 |
| ES2096140T3 (es) | 1997-03-01 |
| HUT64776A (en) | 1994-02-28 |
| AU665676B2 (en) | 1996-01-11 |
| JPH0672899A (ja) | 1994-03-15 |
| NZ247680A (en) | 1995-07-26 |
| HU9301520D0 (en) | 1993-09-28 |
| DE59304389D1 (de) | 1996-12-12 |
| AU3876693A (en) | 1993-12-02 |
| TW274552B (enExample) | 1996-04-21 |
| ATE144991T1 (de) | 1996-11-15 |
| EP0571921A2 (de) | 1993-12-01 |
| IL105795A0 (en) | 1993-09-22 |
| CA2096889A1 (en) | 1993-11-27 |
| FI932351A7 (fi) | 1993-11-27 |
| FI932351A0 (fi) | 1993-05-24 |
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