DK0948527T3 - Cylosporinderivater, fremstilling af disse og farmaceutiske præparater indeholdende disse - Google Patents

Cylosporinderivater, fremstilling af disse og farmaceutiske præparater indeholdende disse

Info

Publication number
DK0948527T3
DK0948527T3 DK97952998T DK97952998T DK0948527T3 DK 0948527 T3 DK0948527 T3 DK 0948527T3 DK 97952998 T DK97952998 T DK 97952998T DK 97952998 T DK97952998 T DK 97952998T DK 0948527 T3 DK0948527 T3 DK 0948527T3
Authority
DK
Denmark
Prior art keywords
derivatives
cylosporin
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
DK97952998T
Other languages
English (en)
Inventor
Jean-Claude Barriere
Georges Bashiardes
Jean-Christophe Carry
Michel Evers
Bruno Filoche
Jean-Pierre Leconte
Serge Mignani
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of DK0948527T3 publication Critical patent/DK0948527T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK97952998T 1996-12-24 1997-12-23 Cylosporinderivater, fremstilling af disse og farmaceutiske præparater indeholdende disse DK0948527T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9615956A FR2757522B1 (fr) 1996-12-24 1996-12-24 Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR1997/002405 WO1998028329A1 (fr) 1996-12-24 1997-12-23 Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
DK0948527T3 true DK0948527T3 (da) 2002-09-16

Family

ID=9499089

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97952998T DK0948527T3 (da) 1996-12-24 1997-12-23 Cylosporinderivater, fremstilling af disse og farmaceutiske præparater indeholdende disse

Country Status (14)

Country Link
US (1) US5965527A (da)
EP (1) EP0948527B1 (da)
JP (1) JP4172822B2 (da)
AT (1) ATE218580T1 (da)
AU (1) AU5669298A (da)
DE (1) DE69713148D1 (da)
DK (1) DK0948527T3 (da)
ES (1) ES2178037T3 (da)
FR (1) FR2757522B1 (da)
MA (1) MA26459A1 (da)
PT (1) PT948527E (da)
TN (1) TNSN97211A1 (da)
WO (1) WO1998028329A1 (da)
ZA (1) ZA9711606B (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1205220C (zh) * 1998-06-12 2005-06-08 斯－凯穆公司 新颖的环孢菌素
ES2255275T3 (es) 1998-07-01 2006-06-16 Debiopharm S.A. Nueva ciclosporina con perfil de actividad mejorado.
US6254860B1 (en) 1999-04-13 2001-07-03 Allergan Sales, Inc. Ocular treatment using cyclosporin-A derivatives
KR100982466B1 (ko) 2001-10-19 2010-09-16 이소테크니카 인코포레이티드 시클로스포린 유사체의 합성
ES2330625T3 (es) * 2001-10-19 2009-12-14 Isotechnika Inc. Preconcentrados de microemulsion de analogos de ciclosporina novedosos.
US6987090B2 (en) * 2002-05-09 2006-01-17 Lg Household & Health Care Ltd. Use of 3-position cyclosporin derivatives for hair growth
KR20040039622A (ko) * 2002-11-04 2004-05-12 주식회사 엘지생활건강 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
NZ554514A (en) * 2004-10-01 2010-10-29 Scynexis Inc 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
US7196161B2 (en) * 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
UA88484C2 (ru) * 2004-10-01 2009-10-26 Дебиофарм Са ПРИМЕНЕНИЕ [D-MeAla]3-[EtVal]4-ЦИКЛОСПОРИНА ДЛЯ ЛЕЧЕНИЯ ИНФЕКЦИИ ГЕПАТИТА С И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, КОТОРАЯ ВКЛЮЧАЕТ [D-MeAla]3-[EtVal]4-ЦИКЛОСПОРИН
NZ555143A (en) * 2004-12-23 2009-12-24 Novartis Ag Compositions for HCV treatment
US20090214464A1 (en) * 2004-12-23 2009-08-27 Beat Weidmann Compounds for flaviviridae treatment
WO2007041631A1 (en) 2005-09-30 2007-04-12 Scynexis, Inc. ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION
US7754685B2 (en) 2005-09-30 2010-07-13 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis C infection
US7696165B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
JP5377293B2 (ja) 2006-05-19 2013-12-25 スシネキス インク 眼疾患の治療及び予防方法
US20100194497A1 (en) * 2006-06-02 2010-08-05 Claude Annie Perrichon Management of active electrons
MX2009003743A (es) * 2006-10-12 2009-06-18 Novartis Ag Uso de ciclosporinas modificadas.
US7576057B2 (en) 2006-11-20 2009-08-18 Scynexis, Inc. Cyclic peptides
WO2008127613A1 (en) * 2007-04-11 2008-10-23 Scynexis, Inc. New pharmaceutical compositions
NZ584356A (en) 2007-09-26 2011-10-28 Univ Oregon Health & Science Cyclic undecapeptides and derivatives as multiple sclerosis therapies
US20090306033A1 (en) * 2008-06-06 2009-12-10 Keqiang Li Novel cyclic peptides
EP2280989B1 (en) 2008-06-06 2016-02-10 Scynexis, Inc. Cyclosporin analogs and their use in the treatment of hcv infections
WO2010006117A2 (en) * 2008-07-10 2010-01-14 Allergan, Inc. Cyclosporin derivatives for treating ocular and dermal diseases and conditions
DE102008060549A1 (de) 2008-12-04 2010-06-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung
CA2748389A1 (en) * 2008-12-31 2010-07-08 Scynexis, Inc. Derivatives of cyclosporin a
US8524671B2 (en) 2009-05-27 2013-09-03 Allergan, Inc Cyclosporin derivatives for treating inflammatory diseases and conditions
GB0912584D0 (en) * 2009-07-20 2009-08-26 Ucl Business Plc Cyclosporin conjugates
US9217015B2 (en) * 2010-07-16 2015-12-22 S&T Global Inc. Cyclosporin derivatives for the treatment and prevention of a viral infection
CN103153330B (zh) * 2010-08-12 2017-08-18 美国科技环球有限公司 新的环孢霉素衍生物在病毒感染的治疗和预防中的应用
RU2013120927A (ru) * 2010-10-12 2014-11-20 Аллерган, Инк. Аналоги циклоспорина
US20120088734A1 (en) 2010-10-12 2012-04-12 Allergan, Inc. Cyclosporin Analogs
US9890198B2 (en) 2010-12-03 2018-02-13 S&T Global Inc. Cyclosporin derivatives and uses thereof
DK2651965T3 (da) 2010-12-15 2019-02-18 Contravir Pharmaceuticals Inc Cyclosporinanalogmolekyler modificeret ved aminosyre 1 og 3
EP2705856A1 (en) 2012-09-07 2014-03-12 Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. Compounds for the treatment of neurodegenerative disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0194972B1 (en) * 1985-03-11 1992-07-29 Sandoz Ag Novel cyclosporins
US4814323A (en) * 1986-03-25 1989-03-21 Andrieu J M Process for the treatment and the prevention of AIDS and other disorders induced by the LAV/HTLV III virus
CZ280909B6 (cs) * 1990-11-02 1996-05-15 Novartis Ag Nové cyklosporiny
AU722858B2 (en) * 1995-07-17 2000-08-10 Scynexis, Inc. Cyclosporin derivatives having an anti-HIV effect

Also Published As

Publication number Publication date
DE69713148D1 (de) 2002-07-11
US5965527A (en) 1999-10-12
EP0948527B1 (fr) 2002-06-05
ZA9711606B (en) 1998-06-25
JP4172822B2 (ja) 2008-10-29
MA26459A1 (fr) 2004-12-20
TNSN97211A1 (fr) 2005-03-15
ATE218580T1 (de) 2002-06-15
WO1998028329A1 (fr) 1998-07-02
FR2757522B1 (fr) 1999-01-29
EP0948527A1 (fr) 1999-10-13
FR2757522A1 (fr) 1998-06-26
ES2178037T3 (es) 2002-12-16
JP2001507346A (ja) 2001-06-05
PT948527E (pt) 2002-11-29
AU5669298A (en) 1998-07-17

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