NO931888L - Cyclopeptider og anvendelser derav p} slimhinner - Google Patents
Cyclopeptider og anvendelser derav p} slimhinnerInfo
- Publication number
- NO931888L NO931888L NO931888A NO931888A NO931888L NO 931888 L NO931888 L NO 931888L NO 931888 A NO931888 A NO 931888A NO 931888 A NO931888 A NO 931888A NO 931888 L NO931888 L NO 931888L
- Authority
- NO
- Norway
- Prior art keywords
- formula
- basic
- amino acid
- physiologically tolerated
- tolerated salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Detergent Compositions (AREA)
Abstract
Forbindelser med generell formel I samt fysiologisk tålbare salter, hvor X er en basisk L- eller D-aminosyre, Y er en nøytral eller basisk L- eller D-aminosyre, Z er en nøytral eller basisk L- eller D-aminosyre, som kan være lik eller forskjellig fra Y, K1 er en N-buntiet ac.ylrest med formel II ; c H .; ¿ ¿ c - co- \ H \ \ '' ° C H 3 / hvor Ar står for er. fenylrest. som eventuelt er substituert med 1. 2 .i l l e r 3 like eller forskjellige fester fra rekken hydroksy, (C1-C4)-alkoksy, amino, karboks.v, (C}-C^ )-alkylamino og halogen, eller er en 2- am i no T i az o l - 4 -y J - r e s t , p er et helt tall fra null t i l 4 og q , n , m og l er uavhengig av .hverandre null eller 1. Anvendelse av forbindelsene med formel I samt fysio- logisk tålbare salter for å oppnå resorpsjon av peptider og proteiner ved anvendelse på slimhinner samt farmasøytiske tilberedninger, som inneholder en farmakologisk virksom mengde av et eller flere peptider eller proteiner samt en forbindelse med formel I eller fysiologisk tålbare salter derav er også beskrevet.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4217350 | 1992-05-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
NO931888D0 NO931888D0 (no) | 1993-05-25 |
NO931888L true NO931888L (no) | 1993-11-29 |
Family
ID=6459729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO931888A NO931888L (no) | 1992-05-26 | 1993-05-25 | Cyclopeptider og anvendelser derav p} slimhinner |
Country Status (18)
Country | Link |
---|---|
US (1) | US5565423A (no) |
EP (1) | EP0571921B1 (no) |
JP (1) | JPH0672899A (no) |
KR (1) | KR940005669A (no) |
AT (1) | ATE144991T1 (no) |
AU (1) | AU665676B2 (no) |
CA (1) | CA2096889A1 (no) |
DE (1) | DE59304389D1 (no) |
DK (1) | DK0571921T3 (no) |
ES (1) | ES2096140T3 (no) |
FI (1) | FI932351A (no) |
GR (1) | GR3021570T3 (no) |
HU (1) | HUT64776A (no) |
IL (1) | IL105795A (no) |
NO (1) | NO931888L (no) |
NZ (1) | NZ247680A (no) |
TW (1) | TW274552B (no) |
ZA (1) | ZA933629B (no) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7153845B2 (en) * | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
US8765177B2 (en) * | 1997-09-12 | 2014-07-01 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
US20070004743A1 (en) * | 2002-02-25 | 2007-01-04 | Xiao Linda L | Intranasal administration of mc4-r agonists |
US6803046B2 (en) * | 2002-08-16 | 2004-10-12 | Bracco International B.V. | Sincalide formulations |
WO2004084859A2 (en) * | 2003-03-21 | 2004-10-07 | Nastech Pharmaceutical Company Inc. | Nasal calcitonin formulations containing chlorobutanol |
US20060004185A1 (en) * | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
US20080261933A1 (en) * | 2007-04-23 | 2008-10-23 | Jens Hoffmann | Combination of progesterone-receptor antagonist together with a lutein-hormone-releasing hormone agonist and antagonist for use in brca mediated diseases |
WO2010075416A1 (en) | 2008-12-23 | 2010-07-01 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
WO2013072695A1 (en) | 2011-11-18 | 2013-05-23 | Novacta Biosystems Limited | Polymyxin derivatives |
KR102354902B1 (ko) | 2013-05-22 | 2022-01-24 | 에버레스트 메디신즈 (싱가포르) 피티이. 리미티드 | 폴리믹신 유도체 및 상이한 항생제와의 조합 요법에 있어서의 이들의 용도 |
FI126143B (en) * | 2015-01-15 | 2016-07-15 | Northern Antibiotics Oy | Polymyxine derivative and its uses |
US11110063B2 (en) | 2017-08-25 | 2021-09-07 | MAIA Pharmaceuticals, Inc. | Storage stable sincalide formulations |
LT3810633T (lt) | 2018-06-25 | 2024-01-10 | Spero Therapeutics, Inc. | Junginiai |
JP6975437B2 (ja) * | 2019-03-25 | 2021-12-01 | 国立大学法人 筑波大学 | 細胞層透過促進剤、薬剤吸収補助用組成物、及び医薬組成物 |
CN117649950B (zh) * | 2024-01-29 | 2024-05-17 | 北京大学第三医院(北京大学第三临床医学院) | 一种催产素药物作用动力学模型及其构建方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2124060B1 (no) * | 1971-02-02 | 1974-04-12 | Rhone Poulenc Sa | |
AU7753787A (en) * | 1986-08-06 | 1988-02-24 | Jean-Luc Fauchere | Production of covalent-linked conjugates from an antibiotic and a non-toxic derivative of polymyxine b |
DE3726324A1 (de) * | 1987-08-07 | 1989-02-16 | Hoechst Ag | Cyclopeptide als resorptionsfoerderer bei applikation auf die schleimhaeute |
US5177059A (en) * | 1989-11-15 | 1993-01-05 | Sandoz Ltd. | Polymyxin B conjugates |
-
1992
- 1992-10-30 TW TW081108642A patent/TW274552B/zh active
-
1993
- 1993-05-24 AT AT93108353T patent/ATE144991T1/de not_active IP Right Cessation
- 1993-05-24 DE DE59304389T patent/DE59304389D1/de not_active Expired - Lifetime
- 1993-05-24 EP EP93108353A patent/EP0571921B1/de not_active Expired - Lifetime
- 1993-05-24 FI FI932351A patent/FI932351A/fi unknown
- 1993-05-24 IL IL105795A patent/IL105795A/en not_active IP Right Cessation
- 1993-05-24 HU HU9301520A patent/HUT64776A/hu unknown
- 1993-05-24 NZ NZ247680A patent/NZ247680A/en unknown
- 1993-05-24 KR KR1019930008937A patent/KR940005669A/ko active IP Right Grant
- 1993-05-24 ES ES93108353T patent/ES2096140T3/es not_active Expired - Lifetime
- 1993-05-24 DK DK93108353.9T patent/DK0571921T3/da active
- 1993-05-25 JP JP5122478A patent/JPH0672899A/ja active Pending
- 1993-05-25 CA CA002096889A patent/CA2096889A1/en not_active Abandoned
- 1993-05-25 AU AU38766/93A patent/AU665676B2/en not_active Ceased
- 1993-05-25 ZA ZA933629A patent/ZA933629B/xx unknown
- 1993-05-25 NO NO931888A patent/NO931888L/no not_active Application Discontinuation
-
1995
- 1995-04-07 US US08/418,882 patent/US5565423A/en not_active Expired - Fee Related
-
1996
- 1996-11-07 GR GR960402904T patent/GR3021570T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US5565423A (en) | 1996-10-15 |
KR940005669A (ko) | 1994-03-22 |
FI932351A0 (fi) | 1993-05-24 |
DK0571921T3 (da) | 1997-04-01 |
ATE144991T1 (de) | 1996-11-15 |
EP0571921A2 (de) | 1993-12-01 |
HUT64776A (en) | 1994-02-28 |
ZA933629B (en) | 1993-12-20 |
ES2096140T3 (es) | 1997-03-01 |
JPH0672899A (ja) | 1994-03-15 |
EP0571921B1 (de) | 1996-11-06 |
CA2096889A1 (en) | 1993-11-27 |
IL105795A (en) | 1998-03-10 |
AU3876693A (en) | 1993-12-02 |
GR3021570T3 (en) | 1997-02-28 |
TW274552B (no) | 1996-04-21 |
DE59304389D1 (de) | 1996-12-12 |
EP0571921A3 (no) | 1994-01-12 |
HU9301520D0 (en) | 1993-09-28 |
NO931888D0 (no) | 1993-05-25 |
AU665676B2 (en) | 1996-01-11 |
IL105795A0 (en) | 1993-09-22 |
NZ247680A (en) | 1995-07-26 |
FI932351A (fi) | 1993-11-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO931888L (no) | Cyclopeptider og anvendelser derav p} slimhinner | |
ATE147756T1 (de) | Neue oral wirksame elastase-inhibitoren | |
DK0948527T3 (da) | Cylosporinderivater, fremstilling af disse og farmaceutiske præparater indeholdende disse | |
GR3023719T3 (en) | Trifluoromethylketone tripeptide derivatives | |
DE69213546T2 (de) | Neue Peptid-Verbindungen und Verfahren zur Herstellung davon | |
FI945975A0 (fi) | Haarautuneella aminoryhmällä substituoituja tiatsoleja, menetelmiä niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia | |
FI883643A0 (fi) | Cyklopeptider som befraemjar absorption under anvaendning pao slemhinnorna. | |
DE3883055D1 (de) | Enkastine: neue glycopeptide mit enkephalinase-hemmender wirkung, verfahren zu ihrer herstellung und ihre verwendung als pharmazeutische praeparate. | |
ATE65086T1 (de) | Peptidderivate von cck8, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |