BR112014012016A2 - compostos - Google Patents

compostos

Info

Publication number
BR112014012016A2
BR112014012016A2 BR112014012016A BR112014012016A BR112014012016A2 BR 112014012016 A2 BR112014012016 A2 BR 112014012016A2 BR 112014012016 A BR112014012016 A BR 112014012016A BR 112014012016 A BR112014012016 A BR 112014012016A BR 112014012016 A2 BR112014012016 A2 BR 112014012016A2
Authority
BR
Brazil
Prior art keywords
compounds
Prior art date
Application number
BR112014012016A
Other languages
English (en)
Inventor
Duperchy Esther
John Dawson Michael
Saadi Mona
Brown Pamela
Nicolaas Wadman Sjoerd
Original Assignee
Cantab Anti-Infectives Ltd
Novacta Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cantab Anti-Infectives Ltd, Novacta Biosystems Ltd filed Critical Cantab Anti-Infectives Ltd
Publication of BR112014012016A2 publication Critical patent/BR112014012016A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
BR112014012016A 2011-11-18 2012-11-16 compostos BR112014012016A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161561361P 2011-11-18 2011-11-18
PCT/GB2012/052844 WO2013072695A1 (en) 2011-11-18 2012-11-16 Polymyxin derivatives

Publications (1)

Publication Number Publication Date
BR112014012016A2 true BR112014012016A2 (pt) 2017-05-16

Family

ID=47297320

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014012016A BR112014012016A2 (pt) 2011-11-18 2012-11-16 compostos

Country Status (15)

Country Link
US (1) US9234006B2 (pt)
EP (1) EP2780357A1 (pt)
JP (1) JP6185920B2 (pt)
KR (1) KR20140091724A (pt)
CN (1) CN103946233A (pt)
AU (1) AU2012338571B2 (pt)
BR (1) BR112014012016A2 (pt)
CA (1) CA2855916A1 (pt)
CO (1) CO7061068A2 (pt)
EA (1) EA024792B1 (pt)
IL (1) IL232278A0 (pt)
MX (1) MX355217B (pt)
SG (1) SG11201402390PA (pt)
TW (1) TWI608019B (pt)
WO (1) WO2013072695A1 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140091724A (ko) 2011-11-18 2014-07-22 노박타 바이오시스템스 리미티드 폴리믹신 유도체
CA2939061C (en) * 2013-05-22 2023-10-24 New Pharma Licence Holdings Limited Polymyxin derivatives and their use in combination therapy together with different antibiotics
LT3116897T (lt) * 2014-03-11 2022-05-10 Spero Therapeutics, Inc. Polimiksino dariniai ir jų panaudojimas kompleksinėje terapijoje kartu su skirtingais antibiotikais
AU2015240435B2 (en) 2014-04-01 2019-09-19 Monash University Polymyxin derivatives as antimicrobial compounds
US20180030092A1 (en) * 2014-11-26 2018-02-01 New Pharma Licence Holdings Limited Compounds
ES2924058T3 (es) 2014-12-16 2022-10-04 Shanghai Micurx Pharmaceutical Co Ltd Polimixinas antimicrobianas para el tratamiento de infecciones bacterianas
FI126143B (en) 2015-01-15 2016-07-15 Northern Antibiotics Oy Polymyxine derivative and its uses
US9763996B2 (en) 2015-01-16 2017-09-19 Northern Antibiotics, Ltd. Polymyxin derivative and uses thereof
US10322187B2 (en) 2015-08-10 2019-06-18 Lehigh University Reduced toxicity molecular conjugates of anti-fungal agents
CA3000032A1 (en) 2015-09-29 2017-04-06 Monash University Antimicrobial polymyxin derivative compounds
KR102544465B1 (ko) * 2016-09-13 2023-06-19 센타우리 테라퓨틱스 리미티드 신규 화합물 및 그의 치료 용도
CN108226315B (zh) * 2016-12-15 2022-04-12 上海医药工业研究院 一种检测多黏菌素e残留量的分析方法
CN111527100A (zh) * 2017-11-02 2020-08-11 昆士兰大学 肽类抗生素
JP2021528449A (ja) 2018-06-25 2021-10-21 スペロ・セラピューティクス・インコーポレーテッド 化合物
CN111690040A (zh) * 2019-03-12 2020-09-22 上海来益生物药物研究开发中心有限责任公司 多粘菌素衍生物、其制备方法和应用
JP7045520B2 (ja) * 2020-01-02 2022-03-31 上海上薬第一生化薬業有限公司 ポリミキシンｂ成分又はその塩、その製造方法及び使用
US20230141981A1 (en) 2020-01-21 2023-05-11 Shanghai Micurx Pharmaceuticals Co., Ltd Novel compounds and composition for targeted therapy of kidney-associated cancers
WO2022098950A1 (en) 2020-11-06 2022-05-12 Spero Therapeutics, Inc. Compounds
CN112755174B (zh) * 2021-02-26 2022-11-18 沈阳药科大学 多粘菌素衍生物及其制备方法和应用
CN115490757A (zh) * 2021-06-18 2022-12-20 华南理工大学 活性氧自由基响应的多粘菌素前药化合物及其应用
NL2030897B1 (en) * 2022-02-11 2023-08-18 Univ Leiden Antibiotic compounds, formulations and methods of use

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2128617A (en) 1982-10-06 1984-05-02 Martti Vaara Polypeptides for use in antibacterial therapy
WO1988000950A2 (en) 1986-08-06 1988-02-11 Fauchere Jean Luc Production of covalent-linked conjugates from an antibiotic and a non-toxic derivative of polymyxine b
US20010021697A1 (en) 1987-09-14 2001-09-13 Henning Lowenstein Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components
TW274552B (pt) 1992-05-26 1996-04-21 Hoechst Ag
US5767068A (en) 1997-02-13 1998-06-16 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
JP2007507512A (ja) 2003-09-30 2007-03-29 コーヒ コーポレーション 熱傷を治療するための組成物および方法
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
CA2694289C (en) * 2006-08-11 2015-04-07 Northern Antibiotics Oy Polymyxin derivatives and uses thereof
US8193148B2 (en) 2008-02-08 2012-06-05 Northern Antibiotics Ltd. Short fatty acid tail polymyxin derivatives and uses thereof
FI20085469A0 (fi) * 2008-02-08 2008-05-16 Northern Antibiotics Oy Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä
US8329645B2 (en) * 2008-02-08 2012-12-11 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
ES2334547B1 (es) 2008-09-10 2010-12-03 Universidad De Barcelona Compuestos peptidicos antibacterianos.
AR074874A1 (es) 2008-12-23 2011-02-16 Biosource Pharm Inc Composiciones antibioticas para el tratamiento de infecciones gram negativas. metodo. uso. compuesto.
CN101851270A (zh) 2009-04-03 2010-10-06 梁浩 一种多粘菌素衍生物及其制备方法
WO2010130007A1 (en) 2009-05-14 2010-11-18 Monash University Antimicrobial compounds
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
WO2012051663A1 (en) 2010-10-21 2012-04-26 Monash University Antimicrobial compounds
WO2012168820A1 (en) * 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
KR20140091724A (ko) 2011-11-18 2014-07-22 노박타 바이오시스템스 리미티드 폴리믹신 유도체
CA2939061C (en) * 2013-05-22 2023-10-24 New Pharma Licence Holdings Limited Polymyxin derivatives and their use in combination therapy together with different antibiotics
LT3116897T (lt) * 2014-03-11 2022-05-10 Spero Therapeutics, Inc. Polimiksino dariniai ir jų panaudojimas kompleksinėje terapijoje kartu su skirtingais antibiotikais

Also Published As

Publication number Publication date
US9234006B2 (en) 2016-01-12
KR20140091724A (ko) 2014-07-22
EP2780357A1 (en) 2014-09-24
JP6185920B2 (ja) 2017-08-23
AU2012338571B2 (en) 2016-06-16
CO7061068A2 (es) 2014-09-19
CN103946233A (zh) 2014-07-23
CA2855916A1 (en) 2013-05-23
WO2013072695A1 (en) 2013-05-23
EA201490634A1 (ru) 2014-12-30
IL232278A0 (en) 2014-06-30
SG11201402390PA (en) 2014-06-27
MX355217B (es) 2018-04-10
MX2014005542A (es) 2014-10-24
JP2014533678A (ja) 2014-12-15
AU2012338571A1 (en) 2014-05-22
EA024792B1 (ru) 2016-10-31
TWI608019B (zh) 2017-12-11
TW201326215A (zh) 2013-07-01
US20150031602A1 (en) 2015-01-29

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Legal Events

Date Code Title Description
B15I Others concerning applications: loss of priority
B12F Other appeals [chapter 12.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: NOVACTA BIOSYSTEMS LIMITED (GB) , NEW PHARMA LICEN

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE

B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B350 Update of information on the portal [chapter 15.35 patent gazette]