IL232278A0 - History of polymyxin - Google Patents

History of polymyxin

Info

Publication number
IL232278A0
IL232278A0 IL232278A IL23227814A IL232278A0 IL 232278 A0 IL232278 A0 IL 232278A0 IL 232278 A IL232278 A IL 232278A IL 23227814 A IL23227814 A IL 23227814A IL 232278 A0 IL232278 A0 IL 232278A0
Authority
IL
Israel
Prior art keywords
polymyxin derivatives
polymyxin
derivatives
Prior art date
Application number
IL232278A
Other languages
English (en)
Hebrew (he)
Original Assignee
Novacta Biosystems Ltd
Cantab Anti Infectives Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novacta Biosystems Ltd, Cantab Anti Infectives Ltd filed Critical Novacta Biosystems Ltd
Publication of IL232278A0 publication Critical patent/IL232278A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL232278A 2011-11-18 2014-04-28 History of polymyxin IL232278A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161561361P 2011-11-18 2011-11-18
PCT/GB2012/052844 WO2013072695A1 (en) 2011-11-18 2012-11-16 Polymyxin derivatives

Publications (1)

Publication Number Publication Date
IL232278A0 true IL232278A0 (en) 2014-06-30

Family

ID=47297320

Family Applications (1)

Application Number Title Priority Date Filing Date
IL232278A IL232278A0 (en) 2011-11-18 2014-04-28 History of polymyxin

Country Status (15)

Country Link
US (1) US9234006B2 (enExample)
EP (1) EP2780357A1 (enExample)
JP (1) JP6185920B2 (enExample)
KR (1) KR20140091724A (enExample)
CN (1) CN103946233A (enExample)
AU (1) AU2012338571B2 (enExample)
BR (1) BR112014012016A2 (enExample)
CA (1) CA2855916A1 (enExample)
CO (1) CO7061068A2 (enExample)
EA (1) EA024792B1 (enExample)
IL (1) IL232278A0 (enExample)
MX (1) MX355217B (enExample)
SG (1) SG11201402390PA (enExample)
TW (1) TWI608019B (enExample)
WO (1) WO2013072695A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013072695A1 (en) 2011-11-18 2013-05-23 Novacta Biosystems Limited Polymyxin derivatives
SI2999711T1 (sl) * 2013-05-22 2022-10-28 Spero Therapeutics, Inc. Derivati polimiksina in njihova uporaba v kombinacijskem zdravljenju skupaj z različnimi antibiotiki
US20170073373A1 (en) * 2014-03-11 2017-03-16 New Pharma Licence Holdings Limited Polymyxin derivatives and their use in combination therapy together with different antibiotics
EP3126376B1 (en) 2014-04-01 2024-08-21 Monash University Polymyxin derivatives as antimicrobial compounds
WO2016083531A1 (en) * 2014-11-26 2016-06-02 New Pharma Licence Holdings Limited Compounds
JP6896628B2 (ja) * 2014-12-16 2021-06-30 シャンハイ ミクウルク ファーマシューティカル シーオー．エルティーディー 細菌感染症の治療のための抗微生物性ポリミキシン
FI126143B (en) 2015-01-15 2016-07-15 Northern Antibiotics Oy Polymyxine derivative and its uses
US9763996B2 (en) 2015-01-16 2017-09-19 Northern Antibiotics, Ltd. Polymyxin derivative and uses thereof
US10322187B2 (en) 2015-08-10 2019-06-18 Lehigh University Reduced toxicity molecular conjugates of anti-fungal agents
AU2016331658B2 (en) * 2015-09-29 2021-04-01 Monash University Antimicrobial polymyxin derivative compounds
WO2018051085A1 (en) * 2016-09-13 2018-03-22 Centauri Therapeutics Limited Novel compounds and therapeutic uses thereof
CN108226315B (zh) * 2016-12-15 2022-04-12 上海医药工业研究院 一种检测多黏菌素e残留量的分析方法
CN111527100A (zh) * 2017-11-02 2020-08-11 昆士兰大学 肽类抗生素
CA3103158A1 (en) 2018-06-25 2020-01-02 Spero Therapeutics, Inc. Compounds
CN111690040A (zh) * 2019-03-12 2020-09-22 上海来益生物药物研究开发中心有限责任公司 多粘菌素衍生物、其制备方法和应用
JP7045520B2 (ja) * 2020-01-02 2022-03-31 上海上薬第一生化薬業有限公司 ポリミキシンｂ成分又はその塩、その製造方法及び使用
WO2021150792A1 (en) 2020-01-21 2021-07-29 Micurx Pharmaceuticals, Inc. Novel compounds and composition for targeted therapy of kidney-associated cancers
TW202233649A (zh) 2020-11-06 2022-09-01 美商斯佩羅治療學股份有限公司 化合物
CN112755174B (zh) * 2021-02-26 2022-11-18 沈阳药科大学 多粘菌素衍生物及其制备方法和应用
WO2022262823A1 (zh) * 2021-06-18 2022-12-22 华南理工大学 活性氧自由基响应的多粘菌素前药化合物及其应用
NL2030897B1 (en) * 2022-02-11 2023-08-18 Univ Leiden Antibiotic compounds, formulations and methods of use

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2128617A (en) 1982-10-06 1984-05-02 Martti Vaara Polypeptides for use in antibacterial therapy
AU7753787A (en) 1986-08-06 1988-02-24 Jean-Luc Fauchere Production of covalent-linked conjugates from an antibiotic and a non-toxic derivative of polymyxine b
US20010021697A1 (en) 1987-09-14 2001-09-13 Henning Lowenstein Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components
TW274552B (enExample) 1992-05-26 1996-04-21 Hoechst Ag
US5767068A (en) 1997-02-13 1998-06-16 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
CA2540742A1 (en) 2003-09-30 2005-04-14 Terry Hicks Compositions and methods for treating burns
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
PT2057185E (pt) * 2006-08-11 2016-06-17 Northern Antibiotics Oy Derivados de polimixina e suas utilizações
US8329645B2 (en) * 2008-02-08 2012-12-11 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
US8193148B2 (en) 2008-02-08 2012-06-05 Northern Antibiotics Ltd. Short fatty acid tail polymyxin derivatives and uses thereof
FI20085469A0 (fi) 2008-02-08 2008-05-16 Northern Antibiotics Oy Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä
ES2334547B1 (es) 2008-09-10 2010-12-03 Universidad De Barcelona Compuestos peptidicos antibacterianos.
AR074874A1 (es) 2008-12-23 2011-02-16 Biosource Pharm Inc Composiciones antibioticas para el tratamiento de infecciones gram negativas. metodo. uso. compuesto.
CN101851270A (zh) 2009-04-03 2010-10-06 梁浩 一种多粘菌素衍生物及其制备方法
WO2010130007A1 (en) 2009-05-14 2010-11-18 Monash University Antimicrobial compounds
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
WO2012051663A1 (en) 2010-10-21 2012-04-26 Monash University Antimicrobial compounds
WO2012168820A1 (en) * 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
WO2013072695A1 (en) 2011-11-18 2013-05-23 Novacta Biosystems Limited Polymyxin derivatives
SI2999711T1 (sl) * 2013-05-22 2022-10-28 Spero Therapeutics, Inc. Derivati polimiksina in njihova uporaba v kombinacijskem zdravljenju skupaj z različnimi antibiotiki
US20170073373A1 (en) * 2014-03-11 2017-03-16 New Pharma Licence Holdings Limited Polymyxin derivatives and their use in combination therapy together with different antibiotics

Also Published As

Publication number Publication date
JP6185920B2 (ja) 2017-08-23
CN103946233A (zh) 2014-07-23
WO2013072695A1 (en) 2013-05-23
US9234006B2 (en) 2016-01-12
MX355217B (es) 2018-04-10
SG11201402390PA (en) 2014-06-27
CA2855916A1 (en) 2013-05-23
TWI608019B (zh) 2017-12-11
CO7061068A2 (es) 2014-09-19
AU2012338571A1 (en) 2014-05-22
AU2012338571B2 (en) 2016-06-16
EA201490634A1 (ru) 2014-12-30
KR20140091724A (ko) 2014-07-22
JP2014533678A (ja) 2014-12-15
EP2780357A1 (en) 2014-09-24
US20150031602A1 (en) 2015-01-29
TW201326215A (zh) 2013-07-01
BR112014012016A2 (pt) 2017-05-16
EA024792B1 (ru) 2016-10-31
MX2014005542A (es) 2014-10-24

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