SG10201913978RA - Anti-mutated kras t cell receptors - Google Patents

Anti-mutated kras t cell receptors

Info

Publication number
SG10201913978RA
SG10201913978RA SG10201913978RA SG10201913978RA SG10201913978RA SG 10201913978R A SG10201913978R A SG 10201913978RA SG 10201913978R A SG10201913978R A SG 10201913978RA SG 10201913978R A SG10201913978R A SG 10201913978RA SG 10201913978R A SG10201913978R A SG 10201913978RA
Authority
SG
Singapore
Prior art keywords
cell receptors
mutated kras
kras
mutated
receptors
Prior art date
Application number
SG10201913978RA
Other languages
English (en)
Inventor
Qiong J Wang
Zhiya Yu
James C Yang
Original Assignee
The United States Of America As Represented By The Secretary
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The United States Of America As Represented By The Secretary filed Critical The United States Of America As Represented By The Secretary
Publication of SG10201913978RA publication Critical patent/SG10201913978RA/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
    • A61K2239/54—Pancreas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001154—Enzymes
    • A61K39/001164—GTPases, e.g. Ras or Rho
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/463—Cellular immunotherapy characterised by recombinant expression
    • A61K39/4632—T-cell receptors [TCR]; antibody T-cell receptor constructs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464454—Enzymes
    • A61K39/464464—GTPases, e.g. Ras or Rho
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
SG10201913978RA 2014-11-26 2015-11-24 Anti-mutated kras t cell receptors SG10201913978RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462084654P 2014-11-26 2014-11-26
US201562171321P 2015-06-05 2015-06-05

Publications (1)

Publication Number Publication Date
SG10201913978RA true SG10201913978RA (en) 2020-03-30

Family

ID=54838442

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201704155UA SG11201704155UA (en) 2014-11-26 2015-11-24 Anti-mutated kras t cell receptors
SG10201913978RA SG10201913978RA (en) 2014-11-26 2015-11-24 Anti-mutated kras t cell receptors

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201704155UA SG11201704155UA (en) 2014-11-26 2015-11-24 Anti-mutated kras t cell receptors

Country Status (18)

Country Link
US (2) US11207394B2 (zh)
EP (3) EP4286407A3 (zh)
JP (2) JP6863893B2 (zh)
KR (1) KR102622784B1 (zh)
CN (2) CN113956349B (zh)
AU (3) AU2015353720B2 (zh)
CA (1) CA2968399A1 (zh)
ES (2) ES2965689T3 (zh)
HK (1) HK1243642A1 (zh)
HU (1) HUE065689T2 (zh)
IL (1) IL252258B (zh)
MX (1) MX2017006865A (zh)
PL (1) PL3223850T3 (zh)
PT (1) PT3223850T (zh)
SA (1) SA517381608B1 (zh)
SG (2) SG11201704155UA (zh)
SI (1) SI3223850T1 (zh)
WO (1) WO2016085904A1 (zh)

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CN114835800A (zh) * 2022-05-27 2022-08-02 重庆医科大学 Tcr或其抗原结合片段及其应用

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EP4286407A3 (en) * 2014-11-26 2024-03-06 The United States of America, as represented by The Secretary, Department of Health and Human Services Anti-mutated kras t cell receptors
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HUE060121T2 (hu) * 2016-08-02 2023-01-28 The U S A As Represented By The Secretary Anti-KRAS-G12D T-sejt receptorok
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CN116063511B (zh) * 2021-09-30 2023-10-03 北京可瑞生物科技有限公司 抗原结合蛋白及其应用
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CN114835800A (zh) * 2022-05-27 2022-08-02 重庆医科大学 Tcr或其抗原结合片段及其应用

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EP3666288A1 (en) 2020-06-17
US11207394B2 (en) 2021-12-28
ES2784261T3 (es) 2020-09-23
ES2965689T3 (es) 2024-04-16
US20220088164A1 (en) 2022-03-24
HUE065689T2 (hu) 2024-06-28
EP4286407A2 (en) 2023-12-06
WO2016085904A1 (en) 2016-06-02
NZ732045A (en) 2024-04-26
EP3223850A1 (en) 2017-10-04
CN113956349A (zh) 2022-01-21
SG11201704155UA (en) 2017-06-29
PT3223850T (pt) 2020-04-13
JP2017536825A (ja) 2017-12-14
EP4286407A3 (en) 2024-03-06
AU2020203465A1 (en) 2020-06-18
MX2017006865A (es) 2018-01-11
KR102622784B1 (ko) 2024-01-09
CN113956349B (zh) 2024-09-06
CN107223134B (zh) 2021-11-16
IL252258B (en) 2021-12-01
EP3223850B1 (en) 2020-01-08
CN107223134A (zh) 2017-09-29
SI3223850T1 (sl) 2020-09-30
CA2968399A1 (en) 2016-06-02
HK1243642A1 (zh) 2018-07-20
AU2020203465B2 (en) 2022-11-17
JP6863893B2 (ja) 2021-04-21
EP3666288B1 (en) 2023-09-27
KR20170099905A (ko) 2017-09-01
US20170304421A1 (en) 2017-10-26
JP7297807B2 (ja) 2023-06-26
IL252258A0 (en) 2017-07-31
PL3223850T3 (pl) 2020-08-24
SA517381608B1 (ar) 2021-03-11
AU2015353720B2 (en) 2020-02-27
AU2015353720A1 (en) 2017-06-08
JP2021104044A (ja) 2021-07-26
AU2023200614A1 (en) 2023-03-09

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