SG10201909629PA - Bioconjugates and uses thereof - Google Patents
Bioconjugates and uses thereofInfo
- Publication number
- SG10201909629PA SG10201909629PA SG10201909629PA SG10201909629PA SG 10201909629P A SG10201909629P A SG 10201909629PA SG 10201909629P A SG10201909629P A SG 10201909629PA SG 10201909629P A SG10201909629P A SG 10201909629PA
- Authority
- SG
- Singapore
- Prior art keywords
- binding unit
- bioconjugates
- peptide
- bioconjugatesand
- vcam
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
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- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562149428P | 2015-04-17 | 2015-04-17 | |
US201562241057P | 2015-10-13 | 2015-10-13 | |
US201562244665P | 2015-10-21 | 2015-10-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201909629PA true SG10201909629PA (en) | 2019-11-28 |
Family
ID=55809257
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201708357QA SG11201708357QA (en) | 2015-04-17 | 2016-04-15 | Bioconjugates and uses thereof |
SG10201909629P SG10201909629PA (en) | 2015-04-17 | 2016-04-15 | Bioconjugates and uses thereof |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201708357QA SG11201708357QA (en) | 2015-04-17 | 2016-04-15 | Bioconjugates and uses thereof |
Country Status (17)
Country | Link |
---|---|
US (3) | US20160331841A1 (zh) |
EP (1) | EP3283124B1 (zh) |
JP (2) | JP2018513879A (zh) |
KR (1) | KR102709827B1 (zh) |
CN (1) | CN107771085B (zh) |
AU (1) | AU2016248341B2 (zh) |
BR (1) | BR112017021970A2 (zh) |
CA (1) | CA2982680A1 (zh) |
EA (1) | EA201792245A1 (zh) |
HK (1) | HK1251183A1 (zh) |
IL (1) | IL254977B (zh) |
MA (1) | MA44262A (zh) |
MX (1) | MX2017013196A (zh) |
PH (1) | PH12017501863A1 (zh) |
SG (2) | SG11201708357QA (zh) |
TW (1) | TW201718019A (zh) |
WO (1) | WO2016168743A1 (zh) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2009228140B2 (en) | 2008-03-27 | 2015-07-02 | Purdue Research Foundation | Collagen-binding synthetic peptidoglycans, preparation, and methods of use |
CA2903450A1 (en) | 2013-03-15 | 2014-09-18 | Symic Biomedical, Inc. | Extracellular matrix-binding synthetic peptidoglycans |
US10426588B2 (en) | 2013-12-10 | 2019-10-01 | Nova Plasma Ltd. | Container, apparatus and method for handling an implant |
US10772931B2 (en) | 2014-04-25 | 2020-09-15 | Purdue Research Foundation | Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction |
AU2015259298A1 (en) | 2014-05-12 | 2017-01-05 | Purdue Research Foundation | Selectin and ICAM/VCAM peptide ligand conjugates |
JP6807601B2 (ja) | 2015-05-11 | 2021-01-06 | ノバ プラズマ リミテッド | インプラントを操作するための装置および方法 |
JP6876217B2 (ja) * | 2017-05-19 | 2021-05-26 | 二村 芳弘 | 抗炎症作用を呈するペプチドグリカン誘導体 |
CN110809478A (zh) * | 2017-07-07 | 2020-02-18 | 斯米克Ip有限公司 | 合成的生物缀合物 |
KR20200026918A (ko) | 2017-07-07 | 2020-03-11 | 시믹 아이피, 엘엘씨 | 화학적으로 변형된 백본을 갖는 생체접합체 |
WO2019035135A1 (en) | 2017-08-16 | 2019-02-21 | Nova Plasma Ltd. | PLASMA PROCESSING OF AN IMPLANT |
WO2019075213A1 (en) * | 2017-10-11 | 2019-04-18 | Northwestern University | HEPARIN CONJUGATED TO PEPTIDES BINDING TO COLLAGEN FOR TARGETING BIOLOGICAL AND SYNTHETIC FABRICS |
JP7457300B2 (ja) * | 2018-08-29 | 2024-03-28 | 国立大学法人 岡山大学 | 神経変性疾患の診断用ペプチドマーカー |
CN109106940B (zh) * | 2018-09-17 | 2021-08-27 | 大连医科大学附属第一医院 | Iellqar作为预防和治疗动脉粥样硬化疾病药物中的应用 |
CN110755597B (zh) * | 2019-10-24 | 2023-07-07 | 广州市希丽生物科技服务有限公司 | 用于预防和治疗类风湿性关节炎的外用药物组合物 |
CN111701073A (zh) * | 2020-06-01 | 2020-09-25 | 天津大学 | 一种基于胶原蛋白模拟肽改性透明质酸的关节注射制剂及其制备方法和应用 |
WO2024124189A1 (en) * | 2022-12-08 | 2024-06-13 | The General Hospital Corporation | Corneal filler |
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AU628910B2 (en) * | 1988-12-20 | 1992-09-24 | La Jolla Cancer Research Foundation | Polypeptide-polymer conjugates active in wound healing |
WO2004045542A2 (en) * | 2002-11-15 | 2004-06-03 | Arizona Board Of Regents Arizona State University | Therapeutic bioconjugates |
KR20080022588A (ko) * | 2005-06-30 | 2008-03-11 | 브리스톨-마이어스 스퀴브 파마 컴퍼니 | 영상화제로서의 히드라지드 컨쥬게이트 |
EP2207810A4 (en) * | 2007-10-12 | 2011-12-07 | London Health Sciences Ct Res Inc | COMPOSITIONS HAVING AN IMPACT ON HYALURONIC ACID MEDIATION ACTIVITY |
US20120100106A1 (en) * | 2009-05-04 | 2012-04-26 | Purdue Research Foundation | Collagen-binding synthetic peptidoglycans for wound healing |
ES2742218T3 (es) * | 2010-06-23 | 2020-02-13 | Purdue Research Foundation | Peptidoglicanos sintéticos que se enlazan al colágeno destinados a ser utilizados en operaciones vasculares |
US9173919B2 (en) * | 2011-02-16 | 2015-11-03 | Purdue Research Foundation | Collagen-targeted nanoparticles |
KR102006036B1 (ko) * | 2011-05-24 | 2019-07-31 | 시믹 아이피, 엘엘씨 | 히알루론산-결합 합성 펩티도글리칸 및 이의 제조 및 이용 방법 |
US10494402B2 (en) * | 2012-11-25 | 2019-12-03 | The Regents Of The University Of California | Peptides that stimulate subcutaneous adipogenesis |
CA2903450A1 (en) * | 2013-03-15 | 2014-09-18 | Symic Biomedical, Inc. | Extracellular matrix-binding synthetic peptidoglycans |
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EP3283124B1 (en) | 2024-04-24 |
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AU2016248341B2 (en) | 2021-08-19 |
IL254977B (en) | 2021-03-25 |
JP7289036B2 (ja) | 2023-06-09 |
CN107771085A (zh) | 2018-03-06 |
KR102709827B1 (ko) | 2024-09-24 |
CN107771085B (zh) | 2024-09-03 |
IL254977A (en) | 2019-08-29 |
JP2018513879A (ja) | 2018-05-31 |
AU2016248341A1 (en) | 2017-11-30 |
JP2021042238A (ja) | 2021-03-18 |
US20220313830A1 (en) | 2022-10-06 |
EA201792245A1 (ru) | 2018-07-31 |
TW201718019A (zh) | 2017-06-01 |
MA44262A (fr) | 2021-03-24 |
KR20180016988A (ko) | 2018-02-20 |
HK1251183A1 (zh) | 2019-01-25 |
EP3283124A1 (en) | 2018-02-21 |
SG11201708357QA (en) | 2017-11-29 |
PH12017501863A1 (en) | 2018-03-05 |
US20200078469A1 (en) | 2020-03-12 |
CA2982680A1 (en) | 2016-10-20 |
WO2016168743A1 (en) | 2016-10-20 |
BR112017021970A2 (pt) | 2018-07-10 |
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