SE9700937D0 - Powder inhaler I - Google Patents

Powder inhaler I

Info

Publication number
SE9700937D0
SE9700937D0 SE9700937A SE9700937A SE9700937D0 SE 9700937 D0 SE9700937 D0 SE 9700937D0 SE 9700937 A SE9700937 A SE 9700937A SE 9700937 A SE9700937 A SE 9700937A SE 9700937 D0 SE9700937 D0 SE 9700937D0
Authority
SE
Sweden
Prior art keywords
flow path
powder
dosing means
inhalation
stream
Prior art date
Application number
SE9700937A
Other languages
English (en)
Swedish (sv)
Inventor
Jan Andersson
John Conway
Allan Dagsland
Stefan Friess
Harald Heckenmueller
Uwe Rollwage
Hans Strid
Volker Tiedemann
Jan Trofast
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9700937A priority Critical patent/SE9700937D0/xx
Publication of SE9700937D0 publication Critical patent/SE9700937D0/xx
Priority to TW090206705U priority patent/TW469832U/zh
Priority to ZA9802021A priority patent/ZA982021B/xx
Priority to SK1234-99A priority patent/SK285517B6/sk
Priority to NZ523896A priority patent/NZ523896A/en
Priority to PCT/SE1998/000457 priority patent/WO1998041256A2/en
Priority to CZ0324299A priority patent/CZ298388B6/cs
Priority to ARP980101157A priority patent/AR008957A1/es
Priority to BR9811456-5A priority patent/BR9811456A/pt
Priority to EP98909954A priority patent/EP0979115B1/en
Priority to PT98909954T priority patent/PT979115E/pt
Priority to PCT/SE1998/000465 priority patent/WO1998041264A1/en
Priority to PT04008146T priority patent/PT1454647E/pt
Priority to DE69811655T priority patent/DE69811655T2/de
Priority to PT98909946T priority patent/PT1017438E/pt
Priority to NZ337479A priority patent/NZ337479A/en
Priority to AU64303/98A priority patent/AU741505B2/en
Priority to ES98909946T priority patent/ES2227812T3/es
Priority to ES98909954T priority patent/ES2191928T3/es
Priority to PL98335799A priority patent/PL188765B1/pl
Priority to NZ337478A priority patent/NZ337478A/en
Priority to EP04008146A priority patent/EP1454647B1/en
Priority to HK00105086.4A priority patent/HK1029291B/en
Priority to IL16540098A priority patent/IL165400A0/xx
Priority to DE69826299T priority patent/DE69826299T2/de
Priority to DE69833286T priority patent/DE69833286T2/de
Priority to CNB988050803A priority patent/CN1247275C/zh
Priority to AU64311/98A priority patent/AU6431198A/en
Priority to ES04008146T priority patent/ES2256807T3/es
Priority to US09/066,319 priority patent/US6655380B1/en
Priority to TR1999/02240T priority patent/TR199902240T2/xx
Priority to RU99121399/14A priority patent/RU2201768C2/ru
Priority to CA002283258A priority patent/CA2283258C/en
Priority to DK98909954T priority patent/DK0979115T3/da
Priority to CNB2006100059833A priority patent/CN100500238C/zh
Priority to IL13154798A priority patent/IL131547A0/xx
Priority to MYPI98001119A priority patent/MY124177A/en
Priority to HU0000840A priority patent/HU223792B1/hu
Priority to UA20040604989A priority patent/UA89608C2/uk
Priority to JP54042398A priority patent/JP4138019B2/ja
Priority to DK04008146T priority patent/DK1454647T3/da
Priority to PL98369035A priority patent/PL190261B1/pl
Priority to EP98909946A priority patent/EP1017438B1/en
Priority to AT98909954T priority patent/ATE233113T1/de
Priority to US09/068,474 priority patent/US6257232B1/en
Priority to SI9830700T priority patent/SI1017438T1/xx
Priority to AT04008146T priority patent/ATE316398T1/de
Priority to AT98909946T priority patent/ATE275998T1/de
Priority to CA002283199A priority patent/CA2283199C/en
Priority to JP54043198A priority patent/JP4057066B2/ja
Priority to KR10-1999-7008292A priority patent/KR100466998B1/ko
Priority to TR2000/01837T priority patent/TR200001837T2/xx
Priority to EEP199900403A priority patent/EE04420B1/xx
Priority to IDW990988A priority patent/ID23498A/id
Priority to BR9808312-0A priority patent/BR9808312A/pt
Priority to NZ513357A priority patent/NZ513357A/xx
Priority to UA99095001A priority patent/UA68344C2/uk
Priority to PL98335690A priority patent/PL188855B1/pl
Priority to EEP200400122A priority patent/EE04707B1/xx
Priority to KR10-1999-7008296A priority patent/KR100492839B1/ko
Priority to SA98190222A priority patent/SA98190222B1/ar
Priority to ARP990104216A priority patent/AR020247A2/es
Priority to NO19994432A priority patent/NO321728B1/no
Priority to NO19994434A priority patent/NO322447B1/no
Priority to IS5178A priority patent/IS2780B/is
Priority to HK04109639.4A priority patent/HK1066745B/en
Priority to US10/673,689 priority patent/US7841340B2/en
Priority to US11/125,615 priority patent/US7228860B2/en
Priority to JP2007162777A priority patent/JP2007229523A/ja
Priority to US11/940,346 priority patent/US7779836B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0076—Mechanical counters having a display or indicator on a drum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Nozzles (AREA)
  • Manipulator (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
SE9700937A 1997-03-14 1997-03-14 Powder inhaler I SE9700937D0 (sv)

Priority Applications (70)

Application Number Priority Date Filing Date Title
SE9700937A SE9700937D0 (sv) 1997-03-14 1997-03-14 Powder inhaler I
TW090206705U TW469832U (en) 1997-03-14 1998-03-02 Inhalation device
ZA9802021A ZA982021B (en) 1997-03-14 1998-03-10 Inhalation device.
SK1234-99A SK285517B6 (sk) 1997-03-14 1998-03-13 Inhalačné zariadenie
NZ523896A NZ523896A (en) 1997-03-14 1998-03-13 Inhalation device with dislodging means operative on relative rotation of opposed surfaces
PCT/SE1998/000457 WO1998041256A2 (en) 1997-03-14 1998-03-13 Inhalation device
CZ0324299A CZ298388B6 (cs) 1997-03-14 1998-03-13 Práškový inhalátor
ARP980101157A AR008957A1 (es) 1997-03-14 1998-03-13 Inhalador de polvo para administrar polvo por inhalacion
BR9811456-5A BR9811456A (pt) 1997-03-14 1998-03-13 Dispositivo de inalação
EP98909954A EP0979115B1 (en) 1997-03-14 1998-03-13 Inhalation device
PT98909954T PT979115E (pt) 1997-03-14 1998-03-13 Dispositivo de inalacao
PCT/SE1998/000465 WO1998041264A1 (en) 1997-03-14 1998-03-13 Inhalation device
PT04008146T PT1454647E (pt) 1997-03-14 1998-03-13 Dispositivo de inalacao
DE69811655T DE69811655T2 (de) 1997-03-14 1998-03-13 Inhalationsvorrichtung
PT98909946T PT1017438E (pt) 1997-03-14 1998-03-13 Dispositivo de inalacao
NZ337479A NZ337479A (en) 1997-03-14 1998-03-13 Inhaler including a dose mechanism for providing a dose of powder and a rotatable member
AU64303/98A AU741505B2 (en) 1997-03-14 1998-03-13 Inhalation device
ES98909946T ES2227812T3 (es) 1997-03-14 1998-03-13 Dispositivo de inhalacion.
ES98909954T ES2191928T3 (es) 1997-03-14 1998-03-13 Dispositivo de inhalacion.
PL98335799A PL188765B1 (pl) 1997-03-14 1998-03-13 Inhalator proszkowy do podawania proszku przez inhalacj�
NZ337478A NZ337478A (en) 1997-03-14 1998-03-13 Inhalation device with accumulated powder on surface of flow path dislodged by vibration
EP04008146A EP1454647B1 (en) 1997-03-14 1998-03-13 Inhalation device
HK00105086.4A HK1029291B (en) 1997-03-14 1998-03-13 Inhalation device
IL16540098A IL165400A0 (en) 1997-03-14 1998-03-13 Inhalation device
DE69826299T DE69826299T2 (de) 1997-03-14 1998-03-13 Inhalationsgerät
DE69833286T DE69833286T2 (de) 1997-03-14 1998-03-13 Inhalationsgerät
CNB988050803A CN1247275C (zh) 1997-03-14 1998-03-13 吸入器具
AU64311/98A AU6431198A (en) 1997-03-14 1998-03-13 Inhalation device
ES04008146T ES2256807T3 (es) 1997-03-14 1998-03-13 Dispositivo de inhalacion.
US09/066,319 US6655380B1 (en) 1997-03-14 1998-03-13 Inhalation device
TR1999/02240T TR199902240T2 (xx) 1997-03-14 1998-03-13 �nhalasyon cihaz�.
RU99121399/14A RU2201768C2 (ru) 1997-03-14 1998-03-13 Устройство для ингаляции
CA002283258A CA2283258C (en) 1997-03-14 1998-03-13 Inhalation device
DK98909954T DK0979115T3 (da) 1997-03-14 1998-03-13 Inhalationsanordning
CNB2006100059833A CN100500238C (zh) 1997-03-14 1998-03-13 吸入器具
IL13154798A IL131547A0 (en) 1997-03-14 1998-03-13 Inhalation device
MYPI98001119A MY124177A (en) 1997-03-14 1998-03-13 Inhalation device
HU0000840A HU223792B1 (hu) 1997-03-14 1998-03-13 Porinhalátor
UA20040604989A UA89608C2 (uk) 1997-03-14 1998-03-13 Порошковий інгалятор
JP54042398A JP4138019B2 (ja) 1997-03-14 1998-03-13 吸入器
DK04008146T DK1454647T3 (da) 1997-03-14 1998-03-13 Inhalationsanordning
PL98369035A PL190261B1 (pl) 1997-03-14 1998-03-13 Inhalator proszkowy do podawania proszku przez inhalacj�
EP98909946A EP1017438B1 (en) 1997-03-14 1998-03-13 Inhalation device
AT98909954T ATE233113T1 (de) 1997-03-14 1998-03-13 Inhalationsvorrichtung
US09/068,474 US6257232B1 (en) 1997-03-14 1998-03-13 Inhalation device
SI9830700T SI1017438T1 (en) 1997-03-14 1998-03-13 Inhalation device
AT04008146T ATE316398T1 (de) 1997-03-14 1998-03-13 Inhalationsgerät
AT98909946T ATE275998T1 (de) 1997-03-14 1998-03-13 Inhalationsgerät
CA002283199A CA2283199C (en) 1997-03-14 1998-03-13 Inhalation device
JP54043198A JP4057066B2 (ja) 1997-03-14 1998-03-13 吸入装置
KR10-1999-7008292A KR100466998B1 (ko) 1997-03-14 1998-03-13 흡입 장치
TR2000/01837T TR200001837T2 (tr) 1997-03-14 1998-03-13 İnhilasyon cihazı
EEP199900403A EE04420B1 (et) 1997-03-14 1998-03-13 Pulberinhalaator
IDW990988A ID23498A (id) 1997-03-14 1998-03-13 Peranti inhalasi
BR9808312-0A BR9808312A (pt) 1997-03-14 1998-03-13 Dispositivo de inalação
NZ513357A NZ513357A (en) 1997-03-14 1998-03-13 Inhalation device with powder dislodging member for accumulated powder on surfaces of flow path, with cap covering mouthpiece
UA99095001A UA68344C2 (uk) 1997-03-14 1998-03-13 Порошковий інгалятор (варіанти)
PL98335690A PL188855B1 (pl) 1997-03-14 1998-03-13 Inhalator proszkowy
EEP200400122A EE04707B1 (et) 1997-03-14 1998-03-13 Pulberinhalaator
KR10-1999-7008296A KR100492839B1 (ko) 1997-03-14 1998-03-13 흡입 장치
SA98190222A SA98190222B1 (ar) 1997-03-14 1998-06-29 جهاز استنشاق
ARP990104216A AR020247A2 (es) 1997-03-14 1999-08-23 INHALADOR DE POLVO PARA ADMINISTRAR POLVO MEDIANTE INHALACIoN.
NO19994432A NO321728B1 (no) 1997-03-14 1999-09-13 Innandingsanordning
NO19994434A NO322447B1 (no) 1997-03-14 1999-09-13 Pulverinnhalator
IS5178A IS2780B (is) 1997-03-14 1999-09-13 Innöndunartæki
HK04109639.4A HK1066745B (en) 1997-03-14 2001-01-08 Inhalation device
US10/673,689 US7841340B2 (en) 1997-03-14 2003-09-29 Inhaler with powder dislodging member
US11/125,615 US7228860B2 (en) 1997-03-14 2005-05-09 Inhaler with vibrational powder dislodgement
JP2007162777A JP2007229523A (ja) 1997-03-14 2007-06-20 吸入装置
US11/940,346 US7779836B2 (en) 1997-03-14 2007-11-15 Inhalation device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9700937A SE9700937D0 (sv) 1997-03-14 1997-03-14 Powder inhaler I

Publications (1)

Publication Number Publication Date
SE9700937D0 true SE9700937D0 (sv) 1997-03-14

Family

ID=20406164

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9700937A SE9700937D0 (sv) 1997-03-14 1997-03-14 Powder inhaler I

Country Status (20)

Country Link
US (1) US6257232B1 (enExample)
EP (1) EP0979115B1 (enExample)
JP (2) JP4057066B2 (enExample)
KR (1) KR100466998B1 (enExample)
CN (1) CN100500238C (enExample)
AR (1) AR020247A2 (enExample)
AT (1) ATE233113T1 (enExample)
AU (1) AU6431198A (enExample)
BR (1) BR9808312A (enExample)
CA (1) CA2283199C (enExample)
DE (1) DE69811655T2 (enExample)
DK (1) DK0979115T3 (enExample)
ES (1) ES2191928T3 (enExample)
NO (1) NO322447B1 (enExample)
NZ (1) NZ337479A (enExample)
PL (1) PL188855B1 (enExample)
PT (1) PT979115E (enExample)
SE (1) SE9700937D0 (enExample)
WO (1) WO1998041264A1 (enExample)
ZA (1) ZA982021B (enExample)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU761307B2 (en) * 1997-03-14 2003-06-05 Astra Aktiebolag Inhalation device
SE9700938D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler II and a method of construction thereof
TW469832U (en) * 1997-03-14 2001-12-21 Astra Ab Inhalation device
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
PE20010819A1 (es) * 2000-01-10 2001-09-05 Procter & Gamble Dispositivo para la inhalacion de polvo seco
PT1142601E (pt) * 2000-04-07 2006-05-31 Andi Ventis Ltd Bocal para inalador de particulas
EP1163920B1 (en) 2000-06-13 2004-09-01 Andi-Ventis Limited Mouthpiece for a particulate inhaler
TWI224511B (en) * 2000-06-23 2004-12-01 Norton Healthcare Ltd De-agglomerator for breath-actuated dry powder inhaler
DE10040528A1 (de) * 2000-08-18 2002-02-28 Pari Gmbh Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke
US6681768B2 (en) * 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
JP3619176B2 (ja) * 2001-09-14 2005-02-09 オムロンヘルスケア株式会社 エアロゾル粒子分別装置及び吸入器
US6923175B2 (en) 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
GR1004350B (el) * 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
CN101010305B (zh) 2004-08-20 2010-08-11 曼金德公司 二酮哌嗪合成的催化反应
BR122019022692B1 (pt) 2004-08-23 2023-01-10 Mannkind Corporation Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
CA2586886C (en) * 2004-11-10 2013-09-10 Cipla Limited Inhaler device
KR101384456B1 (ko) 2005-09-14 2014-04-10 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
US8025051B2 (en) * 2005-12-23 2011-09-27 Astrazeneca Ab Delivery device
DE102006007495A1 (de) * 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit
ES2647080T3 (es) 2006-02-22 2017-12-19 Mannkind Corporation Un método para mejorar las propiedades farmacéuticas de micropartículas que comprenden dicetopiperazina y un agente activo
WO2007103152A2 (en) * 2006-03-03 2007-09-13 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
KR100638340B1 (ko) * 2006-03-15 2006-10-27 송인호 낙곡 회수용 흡입기
DE102006047667B3 (de) * 2006-09-28 2008-04-24 Ing. Erich Pfeiffer Gmbh Inhalationsvorrichtung
NZ576637A (en) * 2006-10-25 2012-05-25 Novartis Ag Powder dispersion apparatus with and mediciment receptacles that are cut open using an elliptical arc shaped knife blade oriented to yaw between 4 and 12 degrees
EP2086618A2 (en) * 2006-11-19 2009-08-12 Aespira Ltd. Dry-powder inhaler
WO2011163272A1 (en) 2010-06-21 2011-12-29 Mannkind Corporation Dry powder drug delivery system and methods
EP2279772B1 (en) * 2008-05-23 2016-12-14 Otsuka Pharmaceutical Co., Ltd. Powder inhaler
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
DK2293833T3 (en) 2008-06-13 2016-05-23 Mannkind Corp DRY POWDER INHALER AND MEDICINAL ADMINISTRATION SYSTEM
CA2728523C (en) 2008-06-20 2020-03-10 Mannkind Corporation An interactive apparatus and method for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8551528B2 (en) 2009-06-12 2013-10-08 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
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NZ337479A (en) 2001-05-25
AU6431198A (en) 1998-10-12
CA2283199A1 (en) 1998-09-24
CA2283199C (en) 2007-05-29
CN1810312A (zh) 2006-08-02
DE69811655T2 (de) 2003-12-18
NO994434D0 (no) 1999-09-13
HK1029291A1 (en) 2001-03-30
JP2001517984A (ja) 2001-10-09
JP4057066B2 (ja) 2008-03-05
DE69811655D1 (de) 2003-04-03
PL335690A1 (en) 2000-05-08
WO1998041264A1 (en) 1998-09-24
US6257232B1 (en) 2001-07-10
KR100466998B1 (ko) 2005-01-24
BR9808312A (pt) 2000-05-16
EP0979115A1 (en) 2000-02-16
KR20000076198A (ko) 2000-12-26
NO322447B1 (no) 2006-10-09
NO994434L (no) 1999-11-03
CN100500238C (zh) 2009-06-17
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DK0979115T3 (da) 2003-05-19
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