ES2191928T3 - Dispositivo de inhalacion. - Google Patents

Dispositivo de inhalacion.

Info

Publication number
ES2191928T3
ES2191928T3 ES98909954T ES98909954T ES2191928T3 ES 2191928 T3 ES2191928 T3 ES 2191928T3 ES 98909954 T ES98909954 T ES 98909954T ES 98909954 T ES98909954 T ES 98909954T ES 2191928 T3 ES2191928 T3 ES 2191928T3
Authority
ES
Spain
Prior art keywords
flow path
dust
dosing
inhaler
inhalation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98909954T
Other languages
English (en)
Inventor
Jan Andersson
Allan Dagsland
Kjell Wetterlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of ES2191928T3 publication Critical patent/ES2191928T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0076—Mechanical counters having a display or indicator on a drum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Nozzles (AREA)
  • Manipulator (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

Un inhalador para administrar polvo por inhalación que comprende: un desplazamiento de flujo definido por una pluralidad de superficies a través de las cuales una corriente de aire es aspirada por un usuario durante la inhalación, incluyendo el recorrido del flujo una pieza bucal (2); y medios de dosificación (18) para proporcionar una dosis de polvo al recorrido del flujo en la corriente de aire; caracterizado porque el inhalador comprende además un órgano amovible aguas abajo del medio de dosificación (18) para inhibir la acumulación de polvo en una superficie de la trayectoria del flujo aguas abajo del medio de dosificación (18).
ES98909954T 1997-03-14 1998-03-13 Dispositivo de inhalacion. Expired - Lifetime ES2191928T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9700937A SE9700937D0 (sv) 1997-03-14 1997-03-14 Powder inhaler I

Publications (1)

Publication Number Publication Date
ES2191928T3 true ES2191928T3 (es) 2003-09-16

Family

ID=20406164

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98909954T Expired - Lifetime ES2191928T3 (es) 1997-03-14 1998-03-13 Dispositivo de inhalacion.

Country Status (21)

Country Link
US (1) US6257232B1 (es)
EP (1) EP0979115B1 (es)
JP (2) JP4057066B2 (es)
KR (1) KR100466998B1 (es)
CN (1) CN100500238C (es)
AR (1) AR020247A2 (es)
AT (1) ATE233113T1 (es)
AU (1) AU6431198A (es)
BR (1) BR9808312A (es)
CA (1) CA2283199C (es)
DE (1) DE69811655T2 (es)
DK (1) DK0979115T3 (es)
ES (1) ES2191928T3 (es)
HK (1) HK1029291A1 (es)
NO (1) NO322447B1 (es)
NZ (1) NZ337479A (es)
PL (1) PL188855B1 (es)
PT (1) PT979115E (es)
SE (1) SE9700937D0 (es)
WO (1) WO1998041264A1 (es)
ZA (1) ZA982021B (es)

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US6681768B2 (en) * 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
JP3619176B2 (ja) * 2001-09-14 2005-02-09 オムロンヘルスケア株式会社 エアロゾル粒子分別装置及び吸入器
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
GR1004350B (el) * 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
BR122019022692B1 (pt) 2004-08-23 2023-01-10 Mannkind Corporation Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
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IN2015DN00888A (es) 2006-02-22 2015-07-10 Mannkind Corp
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KR100638340B1 (ko) * 2006-03-15 2006-10-27 송인호 낙곡 회수용 흡입기
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KR101933816B1 (ko) 2008-06-13 2019-03-29 맨카인드 코포레이션 건조 분말 흡입기 및 약물 투여 시스템
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
JP6133270B2 (ja) 2011-04-01 2017-05-24 マンカインド コーポレイション 薬剤カートリッジのためのブリスター包装
CN102218182B (zh) * 2011-06-13 2015-02-18 上海秀新臣邦医药科技有限公司 一种干粉给药装置的振动给药装置
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
ES2624294T3 (es) 2012-07-12 2017-07-13 Mannkind Corporation Sistemas de suministro de fármacos en polvo seco
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP2970149B1 (en) 2013-03-15 2019-08-21 MannKind Corporation Microcrystalline diketopiperazine compositions and methods
BR112016000937A8 (pt) 2013-07-18 2021-06-22 Mannkind Corp formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
US10149951B2 (en) * 2013-10-15 2018-12-11 Mystic Pharmaceuticals, Inc. Controllable rate turbulating nozzle
GB201401154D0 (en) * 2014-01-23 2014-03-12 Team Holdings Uk Ltd Medical apparatus and method
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US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN104971411B (zh) * 2015-06-30 2023-08-29 上海臣邦医药科技股份有限公司 一种粉雾剂给药装置
CN104971415B (zh) * 2015-06-30 2020-06-26 上海臣邦医药科技股份有限公司 一种粉雾剂给药装置的双振动储药单元
CN104971412B (zh) * 2015-06-30 2020-06-26 上海臣邦医药科技股份有限公司 一种粉雾剂给药装置的振动储药单元
CN105031782B (zh) * 2015-06-30 2020-06-26 上海臣邦医药科技股份有限公司 一种提高粉雾剂给药装置加药量计量准确性的方法
CN104971413B (zh) * 2015-06-30 2023-04-14 上海臣邦医药科技股份有限公司 一种粉雾剂给药装置的防误操作单元及防误操作方法
CN111437473B (zh) * 2020-04-16 2023-03-24 宁波诺丁汉大学 一种粉雾剂吸入装置
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Also Published As

Publication number Publication date
NO322447B1 (no) 2006-10-09
JP2007229523A (ja) 2007-09-13
BR9808312A (pt) 2000-05-16
EP0979115A1 (en) 2000-02-16
JP2001517984A (ja) 2001-10-09
US6257232B1 (en) 2001-07-10
HK1029291A1 (en) 2001-03-30
KR20000076198A (ko) 2000-12-26
CN100500238C (zh) 2009-06-17
KR100466998B1 (ko) 2005-01-24
ATE233113T1 (de) 2003-03-15
PT979115E (pt) 2003-07-31
CA2283199A1 (en) 1998-09-24
PL335690A1 (en) 2000-05-08
NO994434L (no) 1999-11-03
AU6431198A (en) 1998-10-12
JP4057066B2 (ja) 2008-03-05
NZ337479A (en) 2001-05-25
NO994434D0 (no) 1999-09-13
EP0979115B1 (en) 2003-02-26
DE69811655D1 (de) 2003-04-03
WO1998041264A1 (en) 1998-09-24
ZA982021B (en) 1999-12-10
SE9700937D0 (sv) 1997-03-14
DK0979115T3 (da) 2003-05-19
CA2283199C (en) 2007-05-29
PL188855B1 (pl) 2005-05-31
CN1810312A (zh) 2006-08-02
DE69811655T2 (de) 2003-12-18
AR020247A2 (es) 2002-05-02

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