ES2191928T3 - Dispositivo de inhalacion. - Google Patents
Dispositivo de inhalacion.Info
- Publication number
- ES2191928T3 ES2191928T3 ES98909954T ES98909954T ES2191928T3 ES 2191928 T3 ES2191928 T3 ES 2191928T3 ES 98909954 T ES98909954 T ES 98909954T ES 98909954 T ES98909954 T ES 98909954T ES 2191928 T3 ES2191928 T3 ES 2191928T3
- Authority
- ES
- Spain
- Prior art keywords
- flow path
- dust
- dosing
- inhaler
- inhalation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000428 dust Substances 0.000 abstract 2
- 238000009825 accumulation Methods 0.000 abstract 1
- 238000006073 displacement reaction Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
- A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
- A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
- A61M15/0071—Mechanical counters having a display or indicator
- A61M15/0076—Mechanical counters having a display or indicator on a drum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Nozzles (AREA)
- Manipulator (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Abstract
Un inhalador para administrar polvo por inhalación que comprende: un desplazamiento de flujo definido por una pluralidad de superficies a través de las cuales una corriente de aire es aspirada por un usuario durante la inhalación, incluyendo el recorrido del flujo una pieza bucal (2); y medios de dosificación (18) para proporcionar una dosis de polvo al recorrido del flujo en la corriente de aire; caracterizado porque el inhalador comprende además un órgano amovible aguas abajo del medio de dosificación (18) para inhibir la acumulación de polvo en una superficie de la trayectoria del flujo aguas abajo del medio de dosificación (18).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9700937A SE9700937D0 (sv) | 1997-03-14 | 1997-03-14 | Powder inhaler I |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2191928T3 true ES2191928T3 (es) | 2003-09-16 |
Family
ID=20406164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98909954T Expired - Lifetime ES2191928T3 (es) | 1997-03-14 | 1998-03-13 | Dispositivo de inhalacion. |
Country Status (21)
Country | Link |
---|---|
US (1) | US6257232B1 (es) |
EP (1) | EP0979115B1 (es) |
JP (2) | JP4057066B2 (es) |
KR (1) | KR100466998B1 (es) |
CN (1) | CN100500238C (es) |
AR (1) | AR020247A2 (es) |
AT (1) | ATE233113T1 (es) |
AU (1) | AU6431198A (es) |
BR (1) | BR9808312A (es) |
CA (1) | CA2283199C (es) |
DE (1) | DE69811655T2 (es) |
DK (1) | DK0979115T3 (es) |
ES (1) | ES2191928T3 (es) |
HK (1) | HK1029291A1 (es) |
NO (1) | NO322447B1 (es) |
NZ (1) | NZ337479A (es) |
PL (1) | PL188855B1 (es) |
PT (1) | PT979115E (es) |
SE (1) | SE9700937D0 (es) |
WO (1) | WO1998041264A1 (es) |
ZA (1) | ZA982021B (es) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW469832U (en) * | 1997-03-14 | 2001-12-21 | Astra Ab | Inhalation device |
SE9700938D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler II and a method of construction thereof |
AU761307B2 (en) * | 1997-03-14 | 2003-06-05 | Astra Aktiebolag | Inhalation device |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
PE20010819A1 (es) * | 2000-01-10 | 2001-09-05 | Procter & Gamble | Dispositivo para la inhalacion de polvo seco |
DE60025889T2 (de) * | 2000-04-07 | 2006-08-03 | Andi-Ventis Ltd. | Mundstück für eine Vorrichtung zum Inhalieren von Partikeln |
EP1163920B1 (en) | 2000-06-13 | 2004-09-01 | Andi-Ventis Limited | Mouthpiece for a particulate inhaler |
TWI224511B (en) * | 2000-06-23 | 2004-12-01 | Norton Healthcare Ltd | De-agglomerator for breath-actuated dry powder inhaler |
DE10040528A1 (de) * | 2000-08-18 | 2002-02-28 | Pari Gmbh | Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke |
US6681768B2 (en) * | 2001-06-22 | 2004-01-27 | Sofotec Gmbh & Co. Kg | Powder formulation disintegrating system and method for dry powder inhalers |
JP3619176B2 (ja) * | 2001-09-14 | 2005-02-09 | オムロンヘルスケア株式会社 | エアロゾル粒子分別装置及び吸入器 |
DE60318938T2 (de) | 2002-03-20 | 2009-01-22 | Mannkind Corp., Valencia | Inhalationsgerät |
GR1004350B (el) * | 2002-03-29 | 2003-09-26 | Συσκευη εισπνοων ξηρης σκονης | |
DK1786784T3 (da) | 2004-08-20 | 2011-02-14 | Mannkind Corp | Katalyse af diketopiperazinsyntese |
JP4990142B2 (ja) | 2004-08-23 | 2012-08-01 | マンカインド コーポレイション | 薬物送達のためのジケトピペラジン塩、ジケトモルホリン塩、又はジケトジオキサン塩 |
WO2006051300A1 (en) * | 2004-11-10 | 2006-05-18 | Cipla Limited | Inhaler |
HUE028691T2 (en) | 2005-09-14 | 2016-12-28 | Mannkind Corp | A method for formulating a drug based on increasing the affinity of crystalline microparticle surfaces towards active ingredients |
WO2007073302A1 (en) * | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | New device |
DE102006007495A1 (de) * | 2006-02-17 | 2007-08-23 | Siegfried Generics International Ag | Dispergiereinheit |
AU2007216966C1 (en) | 2006-02-22 | 2014-03-20 | Mannkind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
AU2007224178B2 (en) * | 2006-03-03 | 2013-03-07 | Stc.Unm | Dry powder inhaler with aeroelastic dispersion mechanism |
KR100638340B1 (ko) * | 2006-03-15 | 2006-10-27 | 송인호 | 낙곡 회수용 흡입기 |
DE102006047667B3 (de) * | 2006-09-28 | 2008-04-24 | Ing. Erich Pfeiffer Gmbh | Inhalationsvorrichtung |
MY151609A (en) | 2006-10-25 | 2014-06-30 | Novartis Ag | Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices |
EP2086618A2 (en) * | 2006-11-19 | 2009-08-12 | Aespira Ltd. | Dry-powder inhaler |
MX2010012729A (es) * | 2008-05-23 | 2010-12-07 | Otsuka Pharma Co Ltd | Inhalador de polvo. |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
ES2655921T3 (es) | 2008-06-13 | 2018-02-22 | Mannkind Corporation | Un inhalador de polvo seco y sistema para administración de fármacos |
ES2904623T3 (es) | 2008-06-20 | 2022-04-05 | Mannkind Corp | Aparato interactivo para establecer un perfil en tiempo real de esfuerzos de inhalación |
TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
EP2405963B1 (en) | 2009-03-11 | 2013-11-06 | MannKind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
WO2010144789A2 (en) | 2009-06-12 | 2010-12-16 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
KR20130117755A (ko) | 2010-06-21 | 2013-10-28 | 맨카인드 코포레이션 | 건조 분말 약물 운반 시스템 및 방법 |
CN105667994B (zh) | 2011-04-01 | 2018-04-06 | 曼金德公司 | 用于药物药盒的泡罩包装 |
CN102218182B (zh) * | 2011-06-13 | 2015-02-18 | 上海秀新臣邦医药科技有限公司 | 一种干粉给药装置的振动给药装置 |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
WO2013063160A1 (en) | 2011-10-24 | 2013-05-02 | Mannkind Corporation | Methods and compositions for treating pain |
CN108057154B (zh) | 2012-07-12 | 2021-04-16 | 曼金德公司 | 干粉药物输送系统和方法 |
US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
JP6523247B2 (ja) | 2013-03-15 | 2019-05-29 | マンカインド コーポレイション | 微結晶性ジケトピペラジン粒子の製造方法および乾燥粉末組成物の製造方法 |
EP3021834A1 (en) | 2013-07-18 | 2016-05-25 | MannKind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
CA2936301C (en) * | 2013-10-15 | 2021-06-08 | Mystic Pharmaceuticals, Inc. | Controllable rate turbulating nozzle |
GB201401154D0 (en) * | 2014-01-23 | 2014-03-12 | Team Holdings Uk Ltd | Medical apparatus and method |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
CN104971415B (zh) * | 2015-06-30 | 2020-06-26 | 上海臣邦医药科技股份有限公司 | 一种粉雾剂给药装置的双振动储药单元 |
CN104971413B (zh) * | 2015-06-30 | 2023-04-14 | 上海臣邦医药科技股份有限公司 | 一种粉雾剂给药装置的防误操作单元及防误操作方法 |
CN104971411B (zh) * | 2015-06-30 | 2023-08-29 | 上海臣邦医药科技股份有限公司 | 一种粉雾剂给药装置 |
CN104971412B (zh) * | 2015-06-30 | 2020-06-26 | 上海臣邦医药科技股份有限公司 | 一种粉雾剂给药装置的振动储药单元 |
CN105031782B (zh) * | 2015-06-30 | 2020-06-26 | 上海臣邦医药科技股份有限公司 | 一种提高粉雾剂给药装置加药量计量准确性的方法 |
CN111437473B (zh) * | 2020-04-16 | 2023-03-24 | 宁波诺丁汉大学 | 一种粉雾剂吸入装置 |
US11925749B2 (en) * | 2021-03-18 | 2024-03-12 | Funai Electric Co., Ltd. | Venting of pharmaceutical drug delivery device for air flow and humidity control |
CN115814216A (zh) * | 2022-11-22 | 2023-03-21 | 东莞市中科智恒新材料有限公司 | 一种高性能电子雾化器 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2470296A (en) | 1948-04-30 | 1949-05-17 | Abbott Lab | Inhalator |
US2573918A (en) | 1949-11-05 | 1951-11-06 | Vick Chemical Company | Device for dispensing medicaments |
GB1295081A (en) * | 1969-01-08 | 1972-11-01 | Fisons Pharmaceuticals Ltd | A method and device for dispensing particulate medicament material from a container |
GB1459426A (en) * | 1973-02-26 | 1976-12-22 | Allen & Hanburys Ltd | Inhalation devices |
US3948264A (en) | 1975-05-21 | 1976-04-06 | Mead Johnson & Company | Inhalation device |
SE411705B (sv) | 1976-11-09 | 1980-02-04 | Draco Ab | Anordning for generering av en avskermad, vesentligen drivmedelsfri aerosol |
EP0069715B1 (en) | 1981-07-08 | 1986-11-05 | Aktiebolaget Draco | Powder inhalator |
AT384552B (de) | 1985-08-01 | 1987-12-10 | Hurka Wilhelm | Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft |
SE453566B (sv) | 1986-03-07 | 1988-02-15 | Draco Ab | Anordning vid pulverinhalatorer |
US4739754A (en) | 1986-05-06 | 1988-04-26 | Shaner William T | Suction resistant inhalator |
ATE138814T1 (de) | 1989-04-28 | 1996-06-15 | Riker Laboratories Inc | Inhalationsvorrichtung für trockenpulver |
IT1237118B (it) * | 1989-10-27 | 1993-05-18 | Miat Spa | Inalatore multidose per farmaci in polvere. |
IL98441A (en) | 1990-06-14 | 1995-12-31 | Rhone Poulenc Rorer Ltd | Powder inhaler |
GB9015522D0 (en) | 1990-07-13 | 1990-08-29 | Braithwaite Philip W | Inhaler |
DE4027391A1 (de) | 1990-08-30 | 1992-03-12 | Boehringer Ingelheim Kg | Treibgasfreies inhalationsgeraet |
EP0548152B1 (en) | 1990-09-12 | 1996-07-24 | BISGAARD, Hans | An inhaling device |
DK0503031T3 (da) | 1990-09-26 | 1999-01-04 | Pharmachemie Bv | Inhalator med et reservoir til flere doser af et materiale, der skal inhaleres |
AU661857B2 (en) | 1991-06-26 | 1995-08-10 | Merck Sharp & Dohme Corp. | Inhalation device for powdered medicaments |
ES2127837T3 (es) * | 1992-10-19 | 1999-05-01 | Dura Pharma Inc | Inhalador para polvo seco. |
EP0668787B1 (en) | 1992-11-12 | 2002-02-27 | Minnesota Mining And Manufacturing Company | Powder inhaler |
AT398277B (de) | 1992-12-11 | 1994-11-25 | Hurka Wilhelm | Inhalationsgerät |
CZ287848B6 (en) | 1992-12-18 | 2001-02-14 | Schering Corp | Inhalator of powder substances |
WO1994023772A2 (en) | 1993-04-06 | 1994-10-27 | Minnesota Mining And Manufacturing Company | Deagglomerators for dry powder inhalers |
US5372128A (en) | 1993-04-14 | 1994-12-13 | Habley Medical Technology Corporation | Fluidizing powder inhaler |
AU1752795A (en) | 1994-03-10 | 1995-09-25 | Franco Del Bon | Inhalator |
GB9419269D0 (en) | 1994-09-23 | 1994-11-09 | Unilever Plc | Aerosol |
-
1997
- 1997-03-14 SE SE9700937A patent/SE9700937D0/xx unknown
-
1998
- 1998-03-10 ZA ZA9802021A patent/ZA982021B/xx unknown
- 1998-03-13 DE DE69811655T patent/DE69811655T2/de not_active Expired - Lifetime
- 1998-03-13 WO PCT/SE1998/000465 patent/WO1998041264A1/en active IP Right Grant
- 1998-03-13 PL PL98335690A patent/PL188855B1/pl unknown
- 1998-03-13 CN CNB2006100059833A patent/CN100500238C/zh not_active Expired - Lifetime
- 1998-03-13 AU AU64311/98A patent/AU6431198A/en not_active Abandoned
- 1998-03-13 AT AT98909954T patent/ATE233113T1/de active
- 1998-03-13 CA CA002283199A patent/CA2283199C/en not_active Expired - Fee Related
- 1998-03-13 NZ NZ337479A patent/NZ337479A/en not_active IP Right Cessation
- 1998-03-13 US US09/068,474 patent/US6257232B1/en not_active Expired - Lifetime
- 1998-03-13 EP EP98909954A patent/EP0979115B1/en not_active Expired - Lifetime
- 1998-03-13 ES ES98909954T patent/ES2191928T3/es not_active Expired - Lifetime
- 1998-03-13 DK DK98909954T patent/DK0979115T3/da active
- 1998-03-13 JP JP54043198A patent/JP4057066B2/ja not_active Expired - Fee Related
- 1998-03-13 PT PT98909954T patent/PT979115E/pt unknown
- 1998-03-13 KR KR10-1999-7008292A patent/KR100466998B1/ko not_active IP Right Cessation
- 1998-03-13 BR BR9808312-0A patent/BR9808312A/pt not_active IP Right Cessation
-
1999
- 1999-08-23 AR ARP990104216A patent/AR020247A2/es active IP Right Grant
- 1999-09-13 NO NO19994434A patent/NO322447B1/no not_active IP Right Cessation
-
2000
- 2000-08-15 HK HK00105086A patent/HK1029291A1/xx not_active IP Right Cessation
-
2007
- 2007-06-20 JP JP2007162777A patent/JP2007229523A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0979115B1 (en) | 2003-02-26 |
CN100500238C (zh) | 2009-06-17 |
KR100466998B1 (ko) | 2005-01-24 |
JP2007229523A (ja) | 2007-09-13 |
NO994434L (no) | 1999-11-03 |
US6257232B1 (en) | 2001-07-10 |
PT979115E (pt) | 2003-07-31 |
PL188855B1 (pl) | 2005-05-31 |
NO322447B1 (no) | 2006-10-09 |
KR20000076198A (ko) | 2000-12-26 |
BR9808312A (pt) | 2000-05-16 |
AR020247A2 (es) | 2002-05-02 |
NZ337479A (en) | 2001-05-25 |
JP4057066B2 (ja) | 2008-03-05 |
JP2001517984A (ja) | 2001-10-09 |
NO994434D0 (no) | 1999-09-13 |
HK1029291A1 (en) | 2001-03-30 |
WO1998041264A1 (en) | 1998-09-24 |
AU6431198A (en) | 1998-10-12 |
PL335690A1 (en) | 2000-05-08 |
DE69811655D1 (de) | 2003-04-03 |
CN1810312A (zh) | 2006-08-02 |
DK0979115T3 (da) | 2003-05-19 |
EP0979115A1 (en) | 2000-02-16 |
CA2283199A1 (en) | 1998-09-24 |
ZA982021B (en) | 1999-12-10 |
DE69811655T2 (de) | 2003-12-18 |
SE9700937D0 (sv) | 1997-03-14 |
CA2283199C (en) | 2007-05-29 |
ATE233113T1 (de) | 2003-03-15 |
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